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Slidable elastic valve bank for prefilling disposable syringe

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CN102861369A CN 201210280897 CN201210280897A CN102861369A CN 102861369 A CN102861369 A CN 102861369A CN 201210280897 CN201210280897 CN 201210280897 CN 201210280897 A CN201210280897 A CN 201210280897A CN 102861369 A CN102861369 A CN 102861369A
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CN 201210280897
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CN102861369B (en )
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A valve bank suitable for prefilling disposable syringes is provided with an inner cavity for storing products for injection, or two independent inner cavities (2) and (3) for storing products (9) and (10) which are separated from each other and are to be mixed before injection, wherein the valve bank is used as a temporary blocking mechanism for blocking the communication between the two inner cavities or between the inner cavities and a pipe communicated with a syringe needle, and the valve bank comprises two cooperated discoid elements (4) and (5) located in a main body (1) of the syringe. The discoid elements has an outer edge leaned against a cylindrical surface of the main body, wherein one of the elements is a slidable elastic discoid plug (4) acting on the second element, and the second element is a receiving slidable discoid seat (5). Edges (19) and (20) which are thicker and smaller in elasticity then other parts of the main body of each element are defined at the bottoms of the two discoid elements. The valve bank is characterized in that the slidable elastic discoid plug (4) comprises an elastic bottom with several holes (14). A hollow blocking plunger (13) with an open bottom extends through the inside of the elastic bottom; and the slidable discoid seat (5) comprises a middle channel pipe (15) relative to the blocking plunger (13); the blocking plunger (13) comprises an inside inlet surrounding an outer cavity to maintain communication with the pipe; The valve bank is also characterized in that the the blocking plunger (13) extending through elastic bottom of the valve plug (4) has a round part with an external diameter slightly larger than the diameter of the channel pipe (15) of the receiving discoid seat (5).


用于预填充一次性注射器的可滑动式弹性阀组 A resilient valve slidably disposable pre-filled syringes

技术领域 FIELD

[0001] 本发明涉及为了保持各组件完全分离和消毒,防止它们在注射前接触针头的用于预填充一次性注射器的弹性可滑动式阀组。 [0001] The present invention relates to various components in order to maintain complete separation and sterilization, to prevent them from contacting the needle prior to injection of a pre-filled disposable syringe elastically sliding valve.

[0002] 该阀组由于在采用相同部件组成的弹性机构集成了新颖的结构改型而脱颖而出,其明显地提高了内部组分的混合和所获溶液的有效且完全的释放。 [0002] Since the same valve member consisting of the elastic means integrated modifications novel structure stands out, which significantly improves the effective release and complete mixing of the components inside and the resultant solution.

[0003] 更具体地,本发明涉及新的阀组类型,其由两个协配的盘状元件组成,盘状元件之一是用作接收盘状阀座的可滑动式弹性盘状阀塞,该盘状阀座也是可滑动的。 [0003] More particularly, the present invention relates to a new type of valve, which is a disk-shaped element composed of two co-operating, one of the disk-shaped element is used as a disk-shaped valve seat slidably receiving resilient disc-like valve plug the disk-shaped valve seat is slidable.

[0004] 已经考虑到组合的修改以确保由组分的内部混合所获得的溶液能够由注射器的单独注射完全排出。 [0004] The modified composition has been considered to ensure that mixing of the components by the internal solution obtained by separate injection syringes can be discharged completely. [0005] 为了获得以上段落中描述的结果,提到的合并在两个协配的阀中的结构改型消除了不期望的移位的所有可能性,所述不期望的移位可以完全地或部分地阻塞在腔室之间的内部连通,并由此影响流体朝向注射针头的流动。 [0005] In order to obtain the results described in the preceding paragraphs, the combined structure modifications mentioned two co-operating valve eliminates all possibility of undesired displacement of the undesired shift may be fully or partially blocked communication between the internal chamber and thereby influence the fluid flow towards the injection needle.

[0006] 本发明是改进型机构的新颖组合以获得预料不到的并且甚至对专家来说都惊讶的更好结果。 [0006] The present invention is a novel combination of an improved mechanism to achieve better results unexpected and even specialists are surprised. 因此,除了其新颖的特性外,为了被认为是发明专利,其结构和功能的构想以遵照法律确定的要求的方式表明了清晰的发明功能。 Thus, in addition to its novel features, it is considered to be patented invention, its structure and function contemplated to comply with legal requirements determine the manner of the present invention show a clear function.

现有技术 current technology

[0007] 预填充的注射器通常包括具有外部和内部的中空圆筒形主体,该外部限定与注射针头连通的轴环,该内部包括轴向定位和可手动滑动的柱塞,其相对于轴环从敞开的基端部向外延伸。 [0007] The pre-filled syringe comprises a generally cylindrical body having a hollow interior and the exterior of the collar and the outer needle defines a communication, including the inner plunger axially positioned and manually slidable with respect to the collar extending outwardly from the base end portion is open. 在上述情况下,限定可变容量的内部腔室,作为用于待注射制品的中转站。 In the above case, the variable volume defined inside the chamber, products to be injected as a relay station. 所述腔室包括主体的圆筒形壁、配合注射针头的所述外轴环,以及可手动滑动并紧密配合在主体的圆筒形壁中的柱塞头部。 The chamber comprises a cylindrical wall body, the outer shaft of the needle fitting ring and can be manually slid and fit tightly in the cylindrical wall of the plunger head in the body.

[0008] 盖子围绕并接合到针头,保持其密封和分离,并且其还接合到注射器导致短暂的密封闭合。 [0008] The needle cover surrounding and bonded to the holding sealing and separation, and which is bonded to the syringe further cause a brief closing of the seal.

[0009] 基于先前提到的基部结构,可以有许多产品,其中所述主体的内部还分隔成两个相邻且共轴的可变容量的腔室。 [0009] Based on the previously mentioned base structure, there may be many products, wherein the inner body further divided into two adjacent and coaxial chambers of variable capacity. 所述腔室由内部的横断隔板分隔,内部横断隔板包括用于腔室间连通的阀机构。 The chambers are separated by an internal transverse partition plate, the internal transverse partition includes a valve mechanism in communication between the chambers.

[0010] 这些注射器已知为双腔室预填充注射器,用于存储两种不同的液体组分或一种液体组分和另一种粉末组分,这些组分必须完全分离并在注射前保持分离。 [0010] The dual chamber syringe known as a pre-filled syringe, for storing two different liquid components or one liquid component and a further powder component, these components must be completely separated and maintained prior to injection separation. 实际上,在这类双腔室预填充注射器的情况中,构成腔室间的隔板的所述内阀机构设计为使用者在注射前可以混合制品而不会被外来杂质污染,也就是说,保持最初的分离。 Indeed, in the case of such a dual-chamber pre-filled syringe, the valve mechanism constituting a separator between the chamber is designed for the user can be mixed prior to injection in the article and will not be extraneous matter, i.e. , to maintain the initial separation. 只有在混合后,针头的盖子可以揭开且获得的混合物可以流入注射用的针头。 Only after mixing, the needle cover may be opened and the obtained mixture flows into the injection needle.

[0011] 为了在所述分离中获得混合物,一般使用柱塞以相反于注射的方向进行移动。 [0011] In order to obtain a mixture in the separation, is generally used to move the plunger in a direction opposite to the injection. 由于这种移动,在相邻的腔室内产生了正压和低压,并且所述的内阀机构被打开以建立允许两种制品的混合的连通,并且同时储存在单个腔室中的混合物准备注射。 Because of this movement, the adjacent chamber creates a positive pressure and a low pressure, and the valve mechanism is opened to establish communication allows two products mixed and simultaneously stored in a single chamber of the mixture ready for injection .

[0012] 一旦获得所述混合,使用者将只能不得不进行注射使得混合物流向针头。 [0012] Once the mixing is obtained, the user will only have to be such that the mixture flows to the injection needle. [0013] 限定了相邻腔室的所述内部阀隔板的各种构造的产品是已知的,其中相邻腔室容纳分离的制品。 [0013] Various configurations defining the inner valve chamber adjacent the separator product are known in which separate adjacent chambers receiving articles. 所述已知的产品由合并在它们的每一个中的阀机构精确区分。 The known products were combined in a precise distinction between them in each of the valve mechanism.

[0014] 然而,从这些内阀的分析中产生不便,即阀机构总是特别设计用于每个特定场合,也就是说,所述机构只能施加到以结构和功能方式适配于机构的一个注射器主体。 [0014] However, the valve is generated from the analysis of these inconveniences, i.e., the valve mechanism is always specifically designed for each particular application, i.e., the mechanism can only be applied to the structures and functions of the embodiment adapted to the mechanism a syringe body.

[0015] 在其它情况下,存在调整为传统注射器主体的阀元件,但是同样要求一些主体的配件或结构变型,所有的这些增加了注射器的最终成本以及使其结构和填充变得复杂。 [0015] In other cases, the presence of the valve element is adjusted to a conventional syringe body, but also requires a number of body parts or structural variants, all of which increases the final cost of the syringe and complicates its structure and fill.

[0016] 本发明的阀组属于适应任意传统的注射器主体的那些组的集合,包括具有一个腔室的那些组和具有两个腔室的那些组。 [0016] The valve of the present invention belongs to the collection of those groups to adapt any conventional syringe body, and those groups including those groups having two chambers with one chamber.

[0017] 阀组的结构和功能的设计已经考虑了适应于任何类型的传统注射器的条件;其没有改变填充制品到注射器的自动过程的事实,特别是在双腔室预填充注射器的情况下;以及混合过程和稍后的注射不需要特别任务的事实。 [0017] The design of the structure and function of the valve has been considered conditions adapted to any type of conventional syringe; the article does not change the fact that the automatic filling process syringes, especially pre-filled syringe in the case of a dual chamber; and later mixing process and the fact that the injection does not require special task. [0018] 还需要注意到为了实现阀组在预填充双腔室注射器中起到有效的作用,配合注射针头和其盖子的所述注射器轴环被塞子或替代地被保持流体与针头内部分离直到注射的合适元件阻塞是重要的,以确保接合和去接合不会产生任何不期望的泄露和溢出。 [0018] Note that in order to achieve required valve play an effective role in the two-chamber pre-filled syringe, with the needle of the syringe with its lid and collar is a plug or alternatively be held separate until the fluid inside the needle suitable injection blocking element is important in order to ensure the engagement and the engagement does not produce any unwanted leakage and spillage.

[0019]这类阀组包括名称为 “C0NJUNT0 VALVULAR EL人STICO Y DESLIZANTE APTO PARAACTUAR EL INTERIOR DE JERINGAS PRLLENADAS”(适合应用于内部预填充的注射器的可滑动式弹性阀组),阿根廷发明专利AR026823B, I (其所有人,Jaime Luis Szapiro, SaiilMoreno y Leonardo Szames,与本发明的申请人相同)的情况,其具有容纳注射用的制品的一个内腔,或容纳注射前必须混合的各自分离的制品的两个单独的内腔的类型,并且其中该阀组作为短暂密封的机构实施,该短暂密封的机构阻塞所述内腔之间或与延伸到注射针头的管之间的连通。 [0019] Such valves comprises entitled "C0NJUNT0 VALVULAR EL al STICO Y DESLIZANTE APTO PARAACTUAR EL INTERIOR DE JERINGAS PRLLENADAS" (suitable for pre-filled syringe inside the slidable resilient valve), Argentine patent AR026823B, I separated from each case the article (its owner, Jaime Luis Szapiro, SaiilMoreno y Leonardo Szames, the same applicant of the present invention) having a receiving lumen for injection of the product, have to be mixed prior to injection or containing two type separate lumen, and wherein the valve sealing means as briefly embodiment, the temporary sealing means blocking communication between said tubes extend to or between the injection needle lumen.

[0020] 该阀组包括两个协配的盘状元件,位于注射器的主体内,外缘靠在主体的圆筒形表面上;其中一个元件是可滑动式弹性盘状阀,同时另一元件是所述盘状阀作用于其上的可滑动式盘状座。 [0020] The valve comprises a disc-shaped member between two co-located within the body of the syringe, against the outer edge surface of the cylindrical body; wherein a resilient element is a disc-like valve slidably, while the other element the disc-like valve is acted upon slidable type plate holder. 该盘状阀具有包括多个孔的弹性底部,短柱从所述孔相对于限定在所述可滑动式盘状座的底部上的对应通道延伸。 The disc-like valve having an elastic bottom comprises a plurality of holes, studs extending from the aperture defined with respect to a corresponding channel on the bottom of said disc-shaped base of the sliding.

[0021] 两个协配的盘状元件的底部的外部边缘称作缘,这些缘比每个阀元件的主体的其余部分更厚和弹性更小。 [0021] The outer edge of the bottom of the disc-shaped element is referred to as two cooperating edges, these edges thicker and less elastic than the rest of the body of each valve member.

[0022] 按照该说明,定位在与注射器的轴环连通的主体内部的所述协配的盘状元件,将能够用作具有一个预填充腔室的注射器用的短暂闭合机构轴环。 [0022] According to the instructions, the disc-shaped element positioned in the interior of the syringe body and the shaft of the communication ring co-operating with the closure mechanism can be used with a short pre-filled syringe chamber collar. 一旦所述盘状元件与阻塞轴环的阀塞结合,同样能够在作为所述腔室之间的隔板的双腔预填充注射器中作为短暂闭合机构。 Once the disc-shaped blocking element and the valve plug collar binding, can likewise be as short closing mechanism in a dual chamber pre-filled syringe as a separator between the chambers.

[0023] 已经证明一旦用于注射的混合物产生并且柱塞向前移动,那么对限定在可滑动的盘状座上的通道的堵塞柱进行支承的所述可滑动式弹性盘状阀位于允许通道释放的位置,但仍然趋向于其堵塞位置。 [0023] Once the mixture has been demonstrated for injection and the plunger moved forward to produce, then the slidable resilient disc-like valve to define a channel slidable disc-shaped seat supporting column clogging in the permitted channel released position, but the trend is still in its blocking position.

[0024] 实际上,有时候当使用者进行注射时,他可以发现所述堵塞柱不正确地进入盘状座的通道孔中,作为不期望的塞子并带来重复最初的运动将塞拉回以释放通道的需要。 [0024] In fact, sometimes when a user injection, he can find the column incorrectly clogging inlet channel hole discoidal base, as the plug and brings undesired duplicate the initial movement back Sierra to release the required channel.

[0025] 这是因为所述堵塞柱对准通道孔,以及虽然杆的直径稍大于孔的直径、但是杆的末端不是杯状的事实。 [0025] This is because the blocked passage holes aligned columns, and slightly larger than the diameter of the hole while the diameter of the rod, but not the end of the rod of the fact that the cup. 因此,杆通过柱塞的压力装配就位,产生不期望的堵塞。 Thus, by press-fitting of the plunger rod in position, undesirable clogging.

[0026] 在该情况下,它足以重复填充、将柱塞拉回的运动,以使杆去耦合。 [0026] In this case, it is sufficient refilled, the movement of the plunger back to decouple the rod. 发明内容 SUMMARY

[0027] 优点 [0027] The advantages

[0028] 本文所指的用于一次性预填充注射器的可滑动式弹性阀座还包括两个协配的盘状元件,位于注射器的主体内,其外缘靠在主体的圆筒形表面上;其中一个元件是作用在另一元件上的可滑动式弹性盘状阀塞,,所述另一元件是接收可滑动式盘状阀座。 [0028] referred to herein resilient seat for slidably disposable pre-filled syringe further comprises a disk-like element co-operating with two, located on the inner cylindrical surface of the syringe body against the outer edges of the body ; wherein a member is slidably resilient action on the other disc-like valve element is a plug member,, the other type plate slidably receiving the valve seat.

[0029] 盘状元件都具有靠着注射器主体的圆筒形表面的外缘。 [0029] The disc-shaped member having a cylindrical surface against an outer edge of the syringe body. 所述缘比每个盘状元件的主体的其余部分更厚和弹性更小。 The edge of each disc-shaped body than the rest of the element is thicker and less elastic.

[0030] 本发明的阀组的阀塞包括具有多个孔的弹性底部。 [0030] The valve plug of a valve according to the present invention comprises a plurality of pores having an elastic bottom. 共轴的堵塞弹性筒体从所述底部的内侧延伸,并由于其中空结构而具有敞开底端。 Clogging flexible tubular body extending coaxially from the inner side of the bottom, and because of the hollow structure having an open bottom end.

[0031] 该弹性筒体正好相与相应的中间通道管相对并定位在所述可滑动式接收盘状座的底部。 [0031] The elastomeric phase corresponding intermediate tubular body just opposite the channel tube and positioned at the bottom of said disc-shaped holder slidably received. 管部分的直径稍小于所述筒体的直径。 Diameter tube portion is slightly smaller than the diameter of the cylindrical body.

[0032] 同样地,所述接收盘状座的特点是有两个直径相对的腔,所述腔邻近中间通道管的出口;即使在所述堵塞筒体位于其阻塞通路的所述出口的位置时也允许流体流动。 [0032] Likewise, the disc-shaped receiving seat is characterized by two diametrically opposed cavities, said cavities adjacent the intermediate outlet channel tube; position of the outlet even when the plugging cylinder is in its blocking passage while also allowing fluid flow.

[0033] 由于具有其敞开端底部的圆筒形堵塞机构的结构,其特点是在注射期间流体压力自身防止接收盘状座阻塞通道。 [0033] Since the cylindrical structure having a plugging mechanism open bottom end thereof, characterized by fluid pressure during the injection itself to prevent the disc-shaped holder receiving passage obstruction.

[0034] 然而,一旦所述堵塞筒体阻塞所述通道的释放出口,那么直径的不同将防止其在通道的中间管内配合,引起闭合作用。 [0034] However, once the obstruction blocking the release cylinder outlet channel, then different diameters which fit to prevent the passage of the intermediate tube, causing the closing action. 在该情况下,邻近所述通道管出口的入口的所述外腔在注射期间确保流体的持续循环到排出出口。 In this case, the outer chamber adjacent said outlet tube passageway to ensure continuous inlet to the discharge outlet of the circulating fluid during injection.

[0035] 一旦认为这是必须的,那么本发明考虑可以表现为邻近通道的所述中间管的入口具有多个外腔。 [0035] Once that this is necessary, then consideration of the present invention may exhibit an external cavity having a plurality of said inlet tube adjacent the intermediate channel.

[0036] 发明作用 [0036] The effect of the invention

[0037] 当前,没有用于遮蔽作用的已知的绝缘膜,从先前的段落中甚至没有暗示结构解决方案的提出。 [0037] Currently, there is an insulating film for the shielding effect is known, from the previous paragraph is not even imply architectural solution proposed solutions. 因此,本申请不仅是新颖的,而且还呈现出清楚的创新行为。 Accordingly, this application is not only innovative, but also showing a clear innovative behavior.


[0038] 除了使用者或专家可以加入本发明中的优点之外,为了详细说明简要描述的优点并帮助理解发明的弹性阀组的结构、构成和功能性的特性,以下描述并示出优选实施例,其以示意性的方式给出并不具有在附加页上的特定范围,由于是优选实施例的事实,短语的解释不限于或排除本发明专利的保护范围。 [0038] In addition to the advantage of the user or the expert can be added in the present invention, a brief description of the advantages to be described in detail and help understanding of the invention the elastic valve structure, composition and functional characteristics, and the following description of a preferred embodiment shown Examples, which are given in a schematic way a particular range on the additional page does not have, as is the fact that the preferred embodiment, interpretation or excluded phrases is not limited to the scope of the present patent disclosure. 该优选实施例旨在解释和示出本发明所基于的基本概念。 This preferred embodiment is intended to explain and illustrate the basic concept of the present invention is based.

[0039] 图I是单独示出构成本发明的弹性阀组的两个元件的横截面视图。 [0039] Figure I is a cross-sectional view of a single two elastic elements constituting the valve of the present invention.

[0040] 图2是与先前附图类似、但在所述元件被配合的情况下的横截面视图。 [0040] FIG. 2 is similar to the previous figures, but in a case where a cross-sectional view of the element of the mating.

[0041] 图3也是与先前两幅附图类似、示出位于能使流体流向注射出口的中间位置的本发明阀组的两个元件的横截面视图。 [0041] FIG. 3 is similar to the previous two drawings, there is shown a cross-sectional view of the fluid flow is located in an intermediate position of the injection outlet of the valve of the present invention enables the two elements.

[0042] 图4是示出从其外侧观察、构成本发明阀座的两个元件之一的弹性可滑动式盘状阀塞的立体图。 [0042] FIG. 4 is a graph showing observed from the outside, a perspective view of the elastic disc-like valve slidably one of the two elements constituting the valve plug of the present invention.

[0043] 图5是示出从其内侧观察、构成本发明阀座的两个元件之一的弹性可滑动式盘状阀塞的立体图。 [0043] FIG. 5 is observed from the inside, perspective view of the elastic disc-like valve slidably one of the two elements constituting the valve plug of the present invention is shown. [0044] 图6是示出从其外侧观察、构成本发明阀座的另一元件的接收可滑动式盘状座的立体图。 [0044] FIG. 6 is a graph showing observed from the outside, a perspective view of the disk-shaped base slidably receives the other element constituting the seat of the present invention.

[0045] 图7是代表从其内侧观察、构成本发明阀座的另一元件的接收可滑动式盘状座的立体图。 [0045] FIG. 7 is a representative of observed from the inside, perspective view of a disc-shaped base slidably receives the other element constituting the seat of the present invention.

[0046] 图8是示出可变容量的双腔室预填充注射器的垂直纵向视图,当其在商业上提供时,本发明的阀组在其中处于备用位置。 [0046] FIG. 8 is a diagram illustrating a dual-chamber pre-filled syringe variable capacity vertical longitudinal view, when it is commercially provided, the present invention in which the valve is in the standby position.

[0047] 图9也是与先前附图类似、示出在注射器内进行混合过程期间本发明阀座所处位置的纵向视图。 [0047] FIG. 9 is similar to the previous figures, shows a longitudinal view of the valve of the present invention, during the location process are mixed in the syringe.

[0048] 图10也是与先前附图类似、示出在注射器内完成混合过程后本发明阀座所处的位置的纵向视图。 [0048] FIG. 10 is similar to the previous figures, shows a longitudinal view of the position of the seat after the completion of the present invention is located within the syringe during mixing. [0049] 图11、12、13是与先前附图类似、示出当传送获得的混合物将用于注射时属于本发明阀组的阀元件位置的纵向视图。 [0049] FIG, 12, 13 is similar to the previous figures, shows that when the obtained mixture was transferred belonging longitudinal view of the valve element position when the valve of the present invention for injection.

[0050] 图14和15是与先前附图类似、示出在注射时本发明阀组的阀元件位置的纵向视图。 [0050] FIGS. 14 and 15 are similar to the previous figures, it shows the valve position of valve element of the present invention, when a longitudinal view of the injection.

[0051] 图16是示出具有可变容量的传统双腔室注射器的纵向视图,其中还包括本发明的阀组,但在该情况下以翻转方式定位阀元件。 [0051] FIG. 16 is a longitudinal view of a conventional dual chamber syringes having a variable capacity, wherein further comprising a valve according to the present invention, but in this case the valve element is positioned in a rollover.

[0052] 图17是与先前附图类似的纵向图,其示出当混合的制品流动以注射时阀元件的操作。 [0052] FIG. 17 is similar to the previous figures and a longitudinal view illustrating the operation when the flow of the mixed product to the injection valve element.

[0053] 值得一提的是,根据被选择以描述的本发明阀座的优选实施例,在所有附图中阀组的相同的或等价的部件或构成元件采用相同的附图标记。 [0053] It is worth mentioning that, according to the selected seat of the present invention is described in preferred embodiments, the same reference numerals in all figures of the same valve or equivalent parts or constituting elements.

具体实施方式 detailed description

[0054] 如在图I和3中所能看到的,本发明中所指的用于预填充注射器的可滑动式弹性阀座包括两个协配的元件,由附图标记4和5指代。 [0054] As FIGS. I and 3 can be seen, the present invention is referred to in the seat for slidably resilient pre-filled syringe comprises two co-operating elements, the reference numerals 4 and 5 refer to generation.

[0055] 由附图标记4指代的协配的元件是可滑动式弹性盘状阀塞,其包括具有略呈杯状的形态、圆形尺寸的弹性盘状底部,在其上限定有多个孔14。 [0055] The co-operating element 4 by the reference numerals refer to the slidable resilient disc-like valve plug, which comprises a cup-shape having a slightly elastic circular disc-shaped bottom dimension, defined thereon a plurality holes 14. 所述盘状底部由更厚和更坚硬的周缘环19包围。 The disk-shaped bottom portion of a thicker and more rigid ring 19 surrounds the periphery.

[0056] 所述塞的特别之处是同轴定位的中空阻塞筒体13从其具有完全敞开底端的内侧延伸。 [0056] The special plug is positioned coaxially from the hollow cylindrical body 13 having an inner blocking completely open bottom end extends.

[0057] 第二元件由附图标记5指代,已经设想为使得所述盘状塞4可以产生阀的关闭或打开,用作协配的接收盘状座。 [0057] The second element 5 by the reference numerals refer to, has been conceived such that the disc-shaped plug 4 can produce the closing or opening the valve, with the disc-shaped receiving seat with CWA. 该元件优选是圆的,具有中心通道管15和各自的周缘环20,该周缘环比主体的其它部分更厚。 The element is preferably a round tube having a central channel 15 and the respective peripheral edge of the ring 20, the peripheral edge of the ring is thicker than the other portion of the body.

[0058] 根据本发明,接收盘状座5的特点在于相对于阀塞的阻塞筒体13的管15的入口包括至少两个外邻近腔21和22,这些腔具有短的高度,每个腔都与所述通道管15连通。 [0058] According to the present invention, the characteristics of the receiving seat 5 is disc-like in that the inlet tube 15 with respect to the valve plug 13 blocking the cylindrical body comprises at least two adjacent outer chambers 21 and 22, which chamber has a short height, each cavity We are in communication with the tube passage 15.

[0059] 这些协配的元件根据所述阀关闭和打开动作必要地一起操作。 [0059] These elements co-operating with opening and closing actions necessary to operate together according to the valve. 为了这样做(如图2中所示),协配的元件中的一个必须放置在第二个协配的元件的顶部且两者必须对准,使得所述阻塞筒体13可以紧紧地配合在管15内,给防止制品流过管的密封闭合提供途径。 To do this (as shown in FIG. 2), a cooperating element of the element to be placed on top of the second co-operating and both must be aligned, so that the blocking cylinder 13 can fit tightly within the tube 15, to prevent product flow through the sealed tube to provide a closed pathway.

[0060] 依照本发明,一旦塞4靠着盘状座5,所述外腔21和22确保流体可以毫无困难地流向排放出口。 [0060] In accordance with the present invention, once the plug 4 against the disc-shaped base 5, the outer chamber 21 and 22 ensure that the fluid can flow without difficulty discharge outlet. [0061] 根据附图8至15,可以理解当本发明的阀应用于双腔室预填充注射器时的操作。 [0061] According to figures 8 to 15, when the valve is to be understood that the present invention is applied to a dual-chamber prefilled syringe operation.

[0062] 这些附图的纵向视图有效地示出了其在注射前提供的传统注射器,也就是说,相应的制品9和10在它们之间适当地分离和隔离并与外界适当地分离和隔离,并存储在注射器主体I内的可变容量2和3的相应腔室内。 [0062] These drawings illustrate a longitudinal view of effectively providing a conventional syringe prior to injection, that is, the corresponding article 9 and 10 appropriately separated and isolated between them and appropriately separated and isolated from the outside variable displacement, and stored in the syringe body I respective chambers 2 and 3.

[0063] 已知注射器具有包围在盖子12中的对应注射针头11。 [0063] In a known injector cap 12 which surrounds a corresponding needle 11. 该盖子接合到轴环18,该轴环位于注射器的上部中,在包括建立密封封闭和由此适当隔离的上部封闭塞16的位置建立内部连通。 The lid 18 is joined to the collar, the collar located at the upper portion of the syringe, including the establishment of the upper seal is closed and thus proper isolation closed position of the plug 16 to establish communication with the interior.

[0064] 这些附图清楚地示出了前腔室2由本发明的阀座4或5在其底部界定,由主体I的圆筒形壁的内侧在其侧部界定,并且由包含处于分离方式的制品9的所述阀塞6在其外侧界定。 [0064] These figures clearly show a front chamber 2 by the valve seat 4 or 5 of the present invention is defined in the bottom thereof, by the inner cylindrical wall of the body I defines at its side portion, and a separation system comprising at article 9 of the valve plug 6 defining on its outside.

[0065] 同样地,存储适当分离的制品10的后腔室3由阀座4或5在其上部界定,由主体I的圆筒形壁的内侧和柱塞8的头7界定。 [0065] Similarly, proper separation of storage chamber 10 after the article 3 in its upper portion defined by the valve seat 4 or 5, defined by the head 7 and the inner cylindrical wall of the plunger body I 8.

[0066] 依照上面所述的条件,如图8、9和16中所不,在所述腔室2和3中存储制品9和10是可行的,制品9和10可以是两种液体组分,或一种液体和一种粉末组分,在两种情况下存储在两个腔室的任一个中。 [0066] In accordance with the above conditions, 8, 9 and 16 are not in the chamber 2, and 3 are stored article 9 and 10 are possible, article 9 and 10 may be two liquid components or a liquid and a powder component, in both cases are stored in either of the two chambers.

[0067] 依照图8、9和10,可以看到在注射前开始制品9和10的混合时本发明阀组的操作。 [0067] In accordance with FIGS. 8, 9 and 10, can be seen prior to the injection operation starts in the article 10 and the mixing valve 9 of the present invention. 为了这样做,使用者沿方向F(相对于注射的方向)向后拉柱塞8,引起腔3内的低压以产生盘状座5的位移,释放腔2和3之间的连通,由于分离,制品9流过阀塞4的孔14和盘状元件5的中央管15。 To do so, the user in the direction F (with respect to the direction of injection) of the plunger 8 is pulled backward, causing the low pressure in the chamber 3 to produce a displacement of the disc-shaped base 5, the release of communication between the chambers 2 and 3, since the separation article 9 through the valve 14 and the plug hole 4 of the disk-shaped element of the central tube 155.

[0068] 图10示出所述元件4和5的位置和从存储在腔3中的与外界隔离并与注射针头的内连通隔离的所述制品9和10的混合所获溶液16的获得。 [0068] FIG. 10 shows the positions 4 and 5 is obtained and stored in the article communication isolated from the outside world in the cavity 3 from the injection needle, and the inner member 10 and the mixed resultant solution 9 16. 其特点是盘状阀5相对于阀塞4位移并由此保持两个腔室2和3之间的连通。 Its characteristics are disc-like valve 5 with respect to the displacement of the spool 4 and thereby keep the communication between the two chambers 2 and 3.

[0069] 图11、12和13示出当使用者沿Fl方向位移柱塞8时由建立的连通所引起的结果,所述溶液16从腔3流向腔2,准备以与任何单腔预填充注射器相同的方式进行注射。 [0069] FIGS. 12 and 13 shows that when the user Fl displaced in the direction of the plunger 8 results due to the communication established, the solution 16 to the chamber 2 from the chamber 3, to prepare a pre-filled single-chamber with any the same manner the syringe for injection.

[0070] 来自柱塞8的压力引起阀塞4的阻塞筒体13靠着通道管15的入口是可行的,在该情况下流体流动不会受到影响,因为其优选地流过外侧邻近腔21和22。 [0070] The pressure from the plunger 8 causes the valve plug 13 against the barrel 4 blocking the inlet channel tube 15 are possible, in which case the fluid flow is not affected, since it preferably flows through the outer chamber 21 adjacent the and 22.

[0071] 在这种意义上,结合在本发明中的新颖结构的解决方案包括具有敞开底端的阻塞筒体,其不能配合在管15中以阻塞连通。 Solution [0071] In this sense, in conjunction with the present invention includes a novel structure having an open bottom end of the blocking cylinder, which is not fit to occlude the tube 15 in communication. 流向排放出口的流体压力趋于膨胀圆筒形壁,以确保其圆形部分比所述管15的圆形部分更大。 Fluid flow pressure discharge outlet of the cylindrical wall tends to expand, to ensure that its circular portion 15 is larger than the circular portion of the tube.

[0072] 然而,如图13、14和15中所示,结合的新颖结构的解决方案包括邻近所述通道15管的连通入口的所述外腔21和22,使得一旦所述阻塞筒体保持靠在通道管15的入口上,流体就可以正常地流过所述腔。 [0072] However, as shown in FIG. 13, 14 and 15, the novel structure of the binding solution comprises said outer chamber of the communication passage 15 adjacent the inlet 21 and tube 22, so that once the blocking cylinder holding rests on the inlet channel tube 15, the fluid can normally flow through the chamber.

[0073] 图13至15示出当使用者沿Fl方向移动柱塞8使得由流体16产生的压力移置阀6且所述流体流过注射针头11,其中盖子12已事先移除。 [0073] Figures 13 to 15 shows that when the user moves the plunger in direction Fl 8 so that the pressure generated by the fluid displacing the valve 16 and the fluid 6 flows through the injection needle 11, wherein the cover 12 has been previously removed.

[0074] 图16和17示出当阀元件4和5处于对换位置时所获得的阀操作。 [0074] FIGS. 16 and 17 shows that when the valve element 4 and the valve 5 is in operation when changing the position obtained. 在此情况下,当使用者沿F方向移动柱塞时,阀塞4将移置以改变其弹性底部,引起阻塞筒体13从其封闭座移置并在内腔之间建立连通,使得储存在腔2中的制品可以流过管15和孔14朝向腔3流动,以组成制品9和10的混合物。 In this case, when the user moves the plunger in the F direction, the spool 4 is displaced to change its bottom spring, causing obstruction and the inner cylindrical body 13 is displaced from the closed to establish communication between the chamber housing, so that the reservoir article 2 in the cavity can flow through the tube 15 and the hole 14 toward the chamber 3 to flow to a mixture of the composition of the article 9 and 10.

[0075] 显然结合在此阀座中的新颖结构的解决方案使其应用于任何传统的预填充注射器。 Solution [0075] Obviously incorporated herein novel configuration of the valve seat so that it is applicable to any conventional pre-filled syringe.

[0076] 事实上,在这些情况下,阀组4和5以这样一种方式定位,S卩,其阻塞与内轴环18的连通,使得单独腔由阀组4或5在其前底部界定,并且由主体I的圆筒形壁和塞头7在其端底部界定。 [0076] In fact, in these cases, the valve 4 and 5 positioned in such a manner, S Jie, which communicates with the blocking ring 18 of the inner shaft, such that a separate valve chamber defined by a bottom 4 or 5 at its front and 7 defined by the cylindrical wall of the body I and the plug at the bottom end thereof. [0077] 在该情况下,使用者还向后拉产生内部低气压的柱塞,产生元件4的弹性改变,并由此阻塞筒体13的位移打开连通,使得存储的制品朝注射针头排出。 [0077] In this case, the user may also pull back the plunger to produce an internal low pressure, elastic element 4 is changed, the displacement of the cylindrical body 13 and thereby blocking the opening of the communication, so that the stored product is discharged toward the injection needle.

Claims (7)

1.用于预填充注射器的可滑动式弹性阀组,具有存储用于注射的制品的一个内腔,或具有两个单独的内腔(2)和(3),以存储在注射前混合的隔离的制品(9)和(10),其中该阀组用作暂时闭合机构,闭塞所述内腔之间或与延伸到注射针头的管之间的连通,包括位于注射器的主体(I)内的两个协配的盘状元件(4)和(5),而且其外缘靠在主体的圆筒形表面上,这些元件中的一个是作用在第二元件上的可滑动式弹性盘状塞(4),第二元件是可滑动式接收盘状座(5),所述盘状元件的底部边缘呈现为缘(19)和(20),所述缘比每个阀元件的主体的其余部分更厚和弹性更小,其特性在于,可滑动式弹性盘状塞(4)包括具有多个孔(14)的弹性底部,具有敞开底端的中空堵塞柱塞(13)从所述弹性底部的内部延伸,同时,可滑动式接收盘状座(5)的特征在于具有相对于所述 Slidably resilient valve 1. A pre-filled syringe having a lumen for injection of the stored articles, or having two separate lumens (2) and (3) to store mixed prior to injection of isolated article (9) and (10), wherein the valve is used as a temporary closure means, or closing the communication between the injection needle and the tube extending between the lumen, located within the syringe comprising a body (I), two co-operating disc-shaped element (4) and (5), and on the outer edges against the cylindrical surface of the body, these elements is a resilient disk-like effect slidably on the second plug element (4), the second member is slidably receiving the disc-shaped seat (5), the bottom edge of the disk-shaped element is rendered edge (19) and (20), the edge of the valve element than the body of each of the remaining thicker portion and less elastic, the characteristics thereof that slidably resilient disc-shaped plug (4) comprises a plurality of apertures having an elastic bottom (14), having an open bottom end of the hollow plunger blockage (13) from said elastic bottom internal extension, at the same time, wherein the disc-shaped slidably receiving seat (5) is characterized with respect to the 堵塞柱塞(13)的中间通道管(15),所述堵塞柱塞(13)具有包围在外腔之间的内部入口,以保持与管内的连通。 Clogging of the plunger (13) of the intermediate channel tube (15), said obturating plunger (13) having an interior an inlet chamber between the outer surround to maintain communication with the inner tube.
2.根据权利要求I所述的用于预填充注射器的可滑动式弹性阀组,其特征在于,其堵塞柱塞(13)从阀塞(4)的弹性底部延伸,所述阀塞(4)具有圆形部分,该圆形部分具有比接收盘状座(5)的通道管(15)直径稍大的外直径。 The resilient valve slidably prefilled syringe according to claim I, characterized in that it blocked the plunger (13) extending from the bottom of the resilient plug (4), said valve plug (4 ) has a circular portion, having an outer diameter than the disc-shaped receiving seat (5) of the channel tube (15) is slightly larger than the diameter of the circular portion.
3.根据权利要求I所述的用于预填充注射器的可滑动式弹性阀组,其特征在于,有两个外腔(21/22)邻近接收可滑动式盘状座(5)的中间通道管(15)出口的入口,这两个外腔在直径上彼此相对。 The resilient valve slidably prefilled syringe according to claim I, characterized in that the two outer chamber (21/22) adjacent to the type plate slidably receiving seat (5) of the intermediate channel inlet and outlet pipe (15), the two outer cavities diametrically opposed to each other.
4.根据权利要求I所述的用于预填充注射器的可滑动式弹性阀组,其特征在于,接收可滑动式盘状座(5)的中间通道管(15)具有被多个腔包围的出口入口,所述多个腔与管的内部连通。 The I according to slidably resilient valve for pre-filled syringe, characterized in that the disc-shaped receiving base slidably formula (5) intermediate the channel tube (15) having a plurality of cavities is surrounded by the claims an inlet, the interior of the tube communicates with the plurality of chambers.
5.根据权利要求I所述的用于预填充注射器的可滑动式弹性阀组,其特征在于,从阀塞(4)延伸的堵塞柱塞(13)包括外部环状凸片,所述凸片临时地靠着接收可滑动式盘状座(5)的通道管(15)的圆筒形表面。 The resilient valve slidably prefilled syringe according to claim I, characterized in that the clogging of the plunger extending from the valve plug (4) (13) comprises an outer annular tab, the projections temporarily against the sheet type plate slidably receiving seat (5) of the channel tube (15) of the cylindrical surface.
6.根据权利要求I所述的用于预填充注射器的可滑动式弹性阀组,其特征在于,协配的盘状元件定位在使主体与注射器的轴环连通的内部中,用作单腔预填充注射器的暂时闭合机构。 The resilient valve slidably prefilled syringe according to claim I, characterized in that the disc-shaped element co-operating with the collar is positioned in the interior of the body in communication with the syringe, used as a single chamber temporary closing means pre-filled syringes.
7.根据权利要求I所述的用于预填充注射器的可滑动式弹性阀组,其特征在于,与阻塞注射器的轴环的阀塞相结合的协配的盘状元件,作为具有同轴地定位在针筒内的双腔室的预填充注射器的暂时闭合机构,以及作为各腔室间的分隔。 The resilient valve slidably prefilled syringe according to claim I, characterized in that the valve plug and the collar of the syringe blocking combining element co-operating disc-shaped, having a coaxially positioned within the barrel of the syringe pre-filled dual chamber temporary closure mechanism, as well as the partition between the chambers.
CN 201210280897 2011-07-04 2012-06-26 Slidable elastic valve bank for prefilling disposable syringe CN102861369B (en)

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Citations (4)

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Publication number Priority date Publication date Assignee Title
DE2455631A1 (en) * 1974-11-25 1976-05-26 Sarstedt Kunststoff Connector for blood-taking syringe - has closure valve preventing flow of blood on exchanging syringe
US6149628A (en) * 1998-07-20 2000-11-21 Szapiro; Jaime Luis Syringe with two variable volume chambers for containing and administering mixtures of products provided separately
US20020068910A1 (en) * 2000-12-05 2002-06-06 Szapiro Jaime Luis Elastic and sliding valvular joint, suitable to work in pre-filled syringes
CN101559247A (en) * 2004-05-03 2009-10-21 灌注技术有限责任公司 Multi-chamber sequential dose dispensing syringe

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2455631A1 (en) * 1974-11-25 1976-05-26 Sarstedt Kunststoff Connector for blood-taking syringe - has closure valve preventing flow of blood on exchanging syringe
US6149628A (en) * 1998-07-20 2000-11-21 Szapiro; Jaime Luis Syringe with two variable volume chambers for containing and administering mixtures of products provided separately
US20020068910A1 (en) * 2000-12-05 2002-06-06 Szapiro Jaime Luis Elastic and sliding valvular joint, suitable to work in pre-filled syringes
CN101559247A (en) * 2004-05-03 2009-10-21 灌注技术有限责任公司 Multi-chamber sequential dose dispensing syringe

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