CN102836274A - Traditional Chinese medicine composition for treating dysfunction caused by injury of spinal cords and peripheral nerves - Google Patents

Traditional Chinese medicine composition for treating dysfunction caused by injury of spinal cords and peripheral nerves Download PDF

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Publication number
CN102836274A
CN102836274A CN201210348639XA CN201210348639A CN102836274A CN 102836274 A CN102836274 A CN 102836274A CN 201210348639X A CN201210348639X A CN 201210348639XA CN 201210348639 A CN201210348639 A CN 201210348639A CN 102836274 A CN102836274 A CN 102836274A
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radix
chinese medicine
medicine composition
pheretima
achyranthis bidentatae
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CN201210348639XA
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CN102836274B (en
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董晓光
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Qingdao Yisheng Jian Integrated Traditional Chinese And Western Medicine Bone Injury Hospital Ltd
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Abstract

The invention relates to a medicine for treating dysfunctional diseases, in particular to a traditional Chinese medicine composition for treating dysfunction caused by the injury of spinal cords and peripheral nerves, which comprises the following components: 50 to 150g of astragalus root, 10 to 50g of radix angelica sinensis, 5 to 20g of red peony root, 10 to 30g of earthworm, 10 to 20g of ligusticum wallichii, 5 to 30g of safflower, 5 to 20g of prepared rehmannia root, 5 to 20g of rhizoma atractylodis, 10 to 20g of rehmannia root, 10 to 40g of radix achyranthis bidentatae, 10 to 20g of eucommia bark and 5 to 30g of radix codonopsis pilosulae. The traditional Chinese medicine composition disclosed by the invention is reasonable in matching and is used for promoting the restoration of nerves by tonifying the kidney, invigorating qi, dredging the tendons and activating the collaterals. By clinical verification, the effect is obvious.

Description

The handicapped Chinese medicine composition that treatment spinal cord and peripheral nerve injury cause
Technical field
The present invention relates to treat the medicine of functional disorder disease, is the handicapped Chinese medicine composition that treatment spinal cord and peripheral nerve injury cause specifically.Especially refer to a kind of Chinese medicine composition of treating the functional disorder disease that spinal cord that a variety of causes causes and peripheral nerve injury cause.
Background technology
Modern medicine does not still have long-term feasible medicine to the treatment of nerve injury at present, and the clinical middle hormone of using impacts, and side effect is huge, and Chinese medicine is taken on heavy responsibilities in this field always.
Summary of the invention
To the defective that exists in the prior art, the handicapped Chinese medicine composition that the object of the present invention is to provide treatment spinal cord and peripheral nerve injury to cause, compatibility is reasonable, and through tonifying Qi of the kidney, tendons relaxing and meridians dredging promotes neural the reparation, and the clinical verification effect is remarkable.
For reaching above purpose, the technical scheme that the present invention takes is:
The handicapped Chinese medicine composition that treatment spinal cord and peripheral nerve injury cause is characterized in that, comprises following component:
The Radix Astragali 50~150g, Radix Angelicae Sinensis 10~50g, Radix Paeoniae Rubra 5~20g, Pheretima 10~30g, Rhizoma Chuanxiong 10~20g, Flos Carthami 5~30g, Radix Rehmanniae Preparata 5~20g, Rhizoma Atractylodis 5~20g Radix Rehmanniae 10~20g, Radix Achyranthis Bidentatae 10~40g, the Cortex Eucommiae 10~20g, Radix Codonopsis 5~30g.
On the basis of technique scheme, comprise following component:
The Radix Astragali 100~140g, Radix Angelicae Sinensis 20~40g, Radix Paeoniae Rubra 5~20g, Pheretima 15~25g, Rhizoma Chuanxiong 10~20g, Flos Carthami 5~15g, Radix Rehmanniae Preparata 5~20g, Rhizoma Atractylodis 5~15g, the Radix Rehmanniae 10~20g, Radix Achyranthis Bidentatae 20~40g, the Cortex Eucommiae 10~20g, Radix Codonopsis 5~15g.
On the basis of technique scheme, comprise following component:
Radix Astragali 120g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 15g, Pheretima 20g, Rhizoma Chuanxiong 15g, Flos Carthami 10g, Radix Rehmanniae Preparata 15g, Rhizoma Atractylodis 10g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 30g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
On the basis of technique scheme, comprise following component:
Radix Astragali 100g, Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 5g, Pheretima 15g, Rhizoma Chuanxiong 10g, Flos Carthami 8g, Radix Rehmanniae Preparata 8g, Rhizoma Atractylodis 8g, Radix Rehmanniae 10g, Radix Achyranthis Bidentatae 20g, Cortex Eucommiae 10g, Radix Codonopsis 5g.
On the basis of technique scheme, comprise following component:
Radix Astragali 110g, Radix Angelicae Sinensis 25g, Radix Paeoniae Rubra 10g, Pheretima 15g, Rhizoma Chuanxiong 15g, Flos Carthami 5g, Radix Rehmanniae Preparata 5g, Rhizoma Atractylodis 5g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 25g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
On the basis of technique scheme, comprise following component:
Radix Astragali 120g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 15g, Pheretima 20g, Rhizoma Chuanxiong 10g, Flos Carthami 10g, Radix Rehmanniae Preparata 10g, Rhizoma Atractylodis 10g, Radix Rehmanniae 10g, Radix Achyranthis Bidentatae 35g, Cortex Eucommiae 20g, Radix Codonopsis 15g.
On the basis of technique scheme, comprise following component:
Radix Astragali 140g, Radix Angelicae Sinensis 40g, Radix Paeoniae Rubra 20g, Pheretima 25g, Rhizoma Chuanxiong 20g, Flos Carthami 15g, Radix Rehmanniae Preparata 20g, Rhizoma Atractylodis 15g, Radix Rehmanniae 20g, Radix Achyranthis Bidentatae 40g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
The handicapped Chinese medicine composition that treatment spinal cord of the present invention and peripheral nerve injury cause, compatibility is reasonable, and through tonifying Qi of the kidney, tendons relaxing and meridians dredging promotes neural the reparation, and the clinical verification effect is remarkable.
The specific embodiment
The functional disorder disease that the traditional Chinese medical science causes spinal cord and peripheral nerve injury is classified as the arthralgia due to stagnation of blood card.Arthralgia due to stagnation of blood card is by element this " weak bone skin Shengs ", labor and sweating, and opening of sweat pores receives mild wind, evilly satisfies the visitor in blood vessels, and it is meciless to cause numbness of the skin, and shape such as migratory arthralgia, but painless are the differences with migratory arthralgia, and that faint and hesitant pulse is held concurrently is tight, explain and coagulates by the stagnant blood vessels of heresy puckery obstructed." element is asked the numbness opinion " said: " ying-qi is empty, and is then meciless.”。
The handicapped Chinese medicine composition that treatment spinal cord of the present invention and peripheral nerve injury cause comprises following component:
The Radix Astragali 50~150g, Radix Angelicae Sinensis 10~50g, Radix Paeoniae Rubra 5~20g, Pheretima 10~30g, Rhizoma Chuanxiong 10~20g, Flos Carthami 5~30g, Radix Rehmanniae Preparata 5~20g, Rhizoma Atractylodis 5~20g Radix Rehmanniae 10~20g, Radix Achyranthis Bidentatae 10~40g, the Cortex Eucommiae 10~20g, Radix Codonopsis 5~30g.
On the basis of technique scheme, comprise following component:
The Radix Astragali 100~140g, Radix Angelicae Sinensis 20~40g, Radix Paeoniae Rubra 5~20g, Pheretima 15~25g, Rhizoma Chuanxiong 10~20g, Flos Carthami 5~15g, Radix Rehmanniae Preparata 5~20g, Rhizoma Atractylodis 5~15g, the Radix Rehmanniae 10~20g, Radix Achyranthis Bidentatae 20~40g, the Cortex Eucommiae 10~20g, Radix Codonopsis 5~15g.
On the basis of technique scheme, comprise following component:
Radix Astragali 120g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 15g, Pheretima 20g, Rhizoma Chuanxiong 15g, Flos Carthami 10g, Radix Rehmanniae Preparata 15g, Rhizoma Atractylodis 10g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 30g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
On the basis of technique scheme, comprise following component:
Radix Astragali 100g, Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 5g, Pheretima 15g, Rhizoma Chuanxiong 10g, Flos Carthami 8g, Radix Rehmanniae Preparata 8g, Rhizoma Atractylodis 8g, Radix Rehmanniae 10g, Radix Achyranthis Bidentatae 20g, Cortex Eucommiae 10g, Radix Codonopsis 5g.
On the basis of technique scheme, comprise following component:
Radix Astragali 110g, Radix Angelicae Sinensis 25g, Radix Paeoniae Rubra 10g, Pheretima 15g, Rhizoma Chuanxiong 15g, Flos Carthami 5g, Radix Rehmanniae Preparata 5g, Rhizoma Atractylodis 5g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 25g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
On the basis of technique scheme, comprise following component:
Radix Astragali 120g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 15g, Pheretima 20g, Rhizoma Chuanxiong 10g, Flos Carthami 10g, Radix Rehmanniae Preparata 10g, Rhizoma Atractylodis 10g, Radix Rehmanniae 10g, Radix Achyranthis Bidentatae 35g, Cortex Eucommiae 20g, Radix Codonopsis 15g.
On the basis of technique scheme, comprise following component:
Radix Astragali 140g, Radix Angelicae Sinensis 40g, Radix Paeoniae Rubra 20g, Pheretima 25g, Rhizoma Chuanxiong 20g, Flos Carthami 15g, Radix Rehmanniae Preparata 20g, Rhizoma Atractylodis 15g, Radix Rehmanniae 20g, Radix Achyranthis Bidentatae 40g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
On the basis of technique scheme, comprise following component:
Radix Astragali 50g, Radix Angelicae Sinensis 10g, Radix Paeoniae Rubra 15g, Pheretima 10g, Rhizoma Chuanxiong 15g, Flos Carthami 30g, Radix Rehmanniae Preparata 15g, Rhizoma Atractylodis 10g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 10g, Cortex Eucommiae 15g, Radix Codonopsis 30g.
On the basis of technique scheme, comprise following component:
Radix Astragali 150g, Radix Angelicae Sinensis 50g, Radix Paeoniae Rubra 15g, Pheretima 30g, Rhizoma Chuanxiong 15g, Flos Carthami 30g, Radix Rehmanniae Preparata 15g, Rhizoma Atractylodis 20g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 10g, Cortex Eucommiae 15g, Radix Codonopsis 30g.
Chinese medicine composition of the present invention is reused Radix Astragali strongly invigorating primordial QI among its side, the prosperous then blood of gas is capable, and all row whole bodies have stronger motive force; Medicine blood circulation promoting and blood stasis dispelling such as Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, open meridians; Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening; Radix Rehmanniae Preparata, the same usefulness of the Radix Rehmanniae, the yin nourishing of enriching blood, life essence-filling, marrow-benefitting, clearing away heat and cooling blood; The Radix Codonopsis invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting.Pheretima, Radix Achyranthis Bidentatae have stronger collateral dredging effect; Take a broad view of full side: invigorating middle warmer has has benefit in logical, logical, mend logical the combination, then QI and blood is sufficient, the stasis of blood is dispelled and network from logical, muscles and bones must be supported so disease is removed.
The Radix Astragali: sweet temperature compensation gas, mend the gas of defending at table;
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving;
Radix Paeoniae Rubra: clots absorbing, pain relieving, removing heat from blood, detumescence;
Pheretima: heat clearing away arresting convulsion, collateral dredging, relieving asthma diuresis;
Rhizoma Chuanxiong: hot loose, resolving depression, sensible, pain relieving;
Flos Carthami: promoting blood circulation to restore menstrual flow, the silt pain relieving of loosing;
Radix Rehmanniae Preparata: the yin nourishing of enriching blood, life essence-filling, marrow-benefitting;
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold;
The Radix Rehmanniae: clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid;
Radix Achyranthis Bidentatae: promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing;
The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening;
Radix Codonopsis: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting;
Play altogether and tonify Qi of the kidney full side, and tendons relaxing and meridians dredging promotes nerve repair function.Be used to treat the functional disorder disease that spinal cord that a variety of causes causes and peripheral nerve injury cause.
Modern pharmacology also confirms to have the blood circulation of improvement more than the Chinese medicine, diminishes inflammation, regulatory enzyme tissue (phospholipase) changes, reduce NO generates, reduces Endothelin, reduce neurocyte necrosis and apoptosis, raising neurotrophic factor content, suppress effects such as excitatory amino acid cytotoxicity; The microcirculatory blood flow at pathological changes spinal cord position is increased; The open number of blood capillary increases; Improve the ischemia anaerobic condition; Reduce blood ET value, thereby blocked ischemia of spinal cord anoxia → edema → increase the weight of anoxybiotic vicious cycle of compressing → ischemia of spinal cord.Wherein effects such as antiinflammatory, anti-stress, raise immunity then can suppress the partial inflammatory change of spinal cord, alleviate edema, alleviate the pressurized situation of spinal cord, and improve the pathological change of spinal cord, promote neurological functional recovery.
Make a general survey of western medical treatment, uncertain therapeutic efficacy is cut, and side effect is high.Main dehydrant, hormone, the neuroprotective etc. used, in prolonged application hormone therapy process, immunity of organisms descends, and the hepatic and renal function damage is serious, influences its prolonged application to a certain extent.We contrast in the treatment to Chinese medicine, Western medicine in the clinical practice of 10 years the pasts.Each has selected the patient of 20 cervical spondylotic myelopathies and spinal cord injury, contrast therapy, and the clinical comparison total effective rate is respectively 85.7%, 66.7%.And Chinese medicine has taking convenience in the therapeutic process, and is cheap, and advantage such as have no adverse reaction is worth clinical expansion.
Chinese medicine composition usage of the present invention is following: before boiling medicine, above prescription was inserted cold water soak 30 minutes, after above prescription is inserted in the container of boiling medicine; Promptly change slow fire after boiling into, fried in shallow oil again 15-30 minute, prevent excessive and too fast the boiling dry of medicine juice when boiling medicine; Should not open pot cover again and again when boiling medicine,, fry in shallow oil and once pour out medicinal liquid to reduce losing of volatile component as far as possible; Fry in shallow oil once with quadrat method again, mix twice medicinal liquid.Get 1 dose of decoction every day of this prescription, every day early, evening 2 times is oral.Avoid irritable foods such as vinegar-pepper, greasy, 7 days each courses of treatment, serve on 2 courses of treatment.
Model case and curative effect:
Lee, the man, 60 years old, it was surplus to suffer from numb limbs and tense tendons 1 year, and night is more so.With vitamin B12 and vitamin B1, surplus the intramuscular injection 60 day, curative effect is not obvious.After change acupuncture and moxibustion therapy into, first pin has little effect, that continues is invalid.Card is seen the lazy speech of the deficiency of vital energy, and more very, buttocks is sent out cold with upper limb for fatigue and weak, numb limbs and tense tendons.Arteries and veins is two heavy thin, pale and tender tongue, white and thin fur.Get Chinese medicine composition of the present invention and control it.Obey 15 doses, all cards are all exempted from.
Qiu, the man, 45 years old, suffer from two upper limb numbness, walk unstable 5 years surplus, row have a medical check-up and imaging examination after be diagnosed as cervical spondylotic myelopathy.Row expectant treatment after being admitted to hospital, the medicines such as dehydration, ganglioside that instil, cooperation acupuncture are treated, and treat and leave hospital after 15 days, the back symptomatic recurrence of leaving hospital, outpatient service is gone to a doctor once more, gets Chinese medicine composition of the present invention and controls it.Obey 25 doses, pain and numbness disappears, and sb.'s illness took a favorable turn, follows up a case by regular visits to not recurrence in a year.
Lee, the man, 45 years old, the builder, traumatic injury causes the damage of neck marrow, the back row cervical vertebra forward and backward road operation of being admitted to hospital, postoperative is used hormone and is impacted, dehydration, neurotrophy medicine impact, course of therapy finishes.Sensation, muscular strength improve not obvious, after give Chinese medicine composition of the present invention and control it, day potion serve on three months, sensation, muscular strength all obtain improvement in various degree.
The content of not doing in this description to describe in detail belongs to this area professional and technical personnel's known prior art.

Claims (7)

1. treat the handicapped Chinese medicine composition that spinal cord and peripheral nerve injury cause, it is characterized in that, comprise following component:
The Radix Astragali 50~150g, Radix Angelicae Sinensis 10~50g, Radix Paeoniae Rubra 5~20g, Pheretima 10~30g, Rhizoma Chuanxiong 10~20g, Flos Carthami 5~30g, Radix Rehmanniae Preparata 5~20g, Rhizoma Atractylodis 5~20g Radix Rehmanniae 10~20g, Radix Achyranthis Bidentatae 10~40g, the Cortex Eucommiae 10~20g, Radix Codonopsis 5~30g.
2. the handicapped Chinese medicine composition that treatment spinal cord as claimed in claim 1 and peripheral nerve injury cause is characterized in that, comprises following component:
The Radix Astragali 100~140g, Radix Angelicae Sinensis 20~40g, Radix Paeoniae Rubra 5~20g, Pheretima 15~25g, Rhizoma Chuanxiong 10~20g, Flos Carthami 5~15g, Radix Rehmanniae Preparata 5~20g, Rhizoma Atractylodis 5~15g, the Radix Rehmanniae 10~20g, Radix Achyranthis Bidentatae 20~40g, the Cortex Eucommiae 10~20g, Radix Codonopsis 5~15g.
3. the handicapped Chinese medicine composition that treatment spinal cord as claimed in claim 2 and peripheral nerve injury cause is characterized in that, comprises following component:
Radix Astragali 120g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 15g, Pheretima 20g, Rhizoma Chuanxiong 15g, Flos Carthami 10g, Radix Rehmanniae Preparata 15g, Rhizoma Atractylodis 10g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 30g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
4. the handicapped Chinese medicine composition that treatment spinal cord as claimed in claim 2 and peripheral nerve injury cause is characterized in that, comprises following component:
Radix Astragali 100g, Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 5g, Pheretima 15g, Rhizoma Chuanxiong 10g, Flos Carthami 8g, Radix Rehmanniae Preparata 8g, Rhizoma Atractylodis 8g, Radix Rehmanniae 10g, Radix Achyranthis Bidentatae 20g, Cortex Eucommiae 10g, Radix Codonopsis 5g.
5. the handicapped Chinese medicine composition that treatment spinal cord as claimed in claim 2 and peripheral nerve injury cause is characterized in that, comprises following component:
Radix Astragali 110g, Radix Angelicae Sinensis 25g, Radix Paeoniae Rubra 10g, Pheretima 15g, Rhizoma Chuanxiong 15g, Flos Carthami 5g, Radix Rehmanniae Preparata 5g, Rhizoma Atractylodis 5g, Radix Rehmanniae 15g, Radix Achyranthis Bidentatae 25g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
6. the handicapped Chinese medicine composition that treatment spinal cord as claimed in claim 2 and peripheral nerve injury cause is characterized in that, comprises following component:
Radix Astragali 120g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 15g, Pheretima 20g, Rhizoma Chuanxiong 10g, Flos Carthami 10g, Radix Rehmanniae Preparata 10g, Rhizoma Atractylodis 10g, Radix Rehmanniae 10g, Radix Achyranthis Bidentatae 35g, Cortex Eucommiae 20g, Radix Codonopsis 15g.
7. the handicapped Chinese medicine composition that treatment spinal cord as claimed in claim 2 and peripheral nerve injury cause is characterized in that, comprises following component:
Radix Astragali 140g, Radix Angelicae Sinensis 40g, Radix Paeoniae Rubra 20g, Pheretima 25g, Rhizoma Chuanxiong 20g, Flos Carthami 15g, Radix Rehmanniae Preparata 20g, Rhizoma Atractylodis 15g, Radix Rehmanniae 20g, Radix Achyranthis Bidentatae 40g, Cortex Eucommiae 15g, Radix Codonopsis 10g.
CN201210348639.XA 2012-09-19 2012-09-19 Traditional Chinese medicine composition for treating dysfunction caused by injury of spinal cords and peripheral nerves Expired - Fee Related CN102836274B (en)

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CN103961555A (en) * 2014-06-02 2014-08-06 刘惠平 Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof
CN104771681A (en) * 2015-04-23 2015-07-15 宋霞 Traditional Chinese medicine preparation for treating urinary incontinence caused by marrow central canal injury
CN105055523A (en) * 2015-08-31 2015-11-18 周晓东 Chinese herb composition for treating acute spinal cord injury and application thereof
CN105169267A (en) * 2015-09-30 2015-12-23 山东大学齐鲁医院 Medicine composition for treating spinal cord injury
US20230043437A1 (en) * 2020-07-20 2023-02-09 Nantong University Compound preparation for neuranagenesis, and preparation method therefor and use thereof
CN116898941A (en) * 2023-07-21 2023-10-20 首都医科大学附属北京中医医院 A traditional Chinese medicine composition and its application, a traditional Chinese medicine preparation and its preparation method and application

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961555A (en) * 2014-06-02 2014-08-06 刘惠平 Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof
CN104771681A (en) * 2015-04-23 2015-07-15 宋霞 Traditional Chinese medicine preparation for treating urinary incontinence caused by marrow central canal injury
CN105055523A (en) * 2015-08-31 2015-11-18 周晓东 Chinese herb composition for treating acute spinal cord injury and application thereof
CN105169267A (en) * 2015-09-30 2015-12-23 山东大学齐鲁医院 Medicine composition for treating spinal cord injury
US20230043437A1 (en) * 2020-07-20 2023-02-09 Nantong University Compound preparation for neuranagenesis, and preparation method therefor and use thereof
US12115204B2 (en) * 2020-07-20 2024-10-15 Nantong University Compound preparation for neuranagenesis, and preparation method therefor and use thereof
CN116898941A (en) * 2023-07-21 2023-10-20 首都医科大学附属北京中医医院 A traditional Chinese medicine composition and its application, a traditional Chinese medicine preparation and its preparation method and application
CN116898941B (en) * 2023-07-21 2024-04-30 首都医科大学附属北京中医医院 Traditional Chinese medicine composition and application thereof, traditional Chinese medicine preparation and preparation method and application thereof

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