CN102830221A - Mixing device of automatic biochemical analyzer - Google Patents
Mixing device of automatic biochemical analyzer Download PDFInfo
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- CN102830221A CN102830221A CN2012103178736A CN201210317873A CN102830221A CN 102830221 A CN102830221 A CN 102830221A CN 2012103178736 A CN2012103178736 A CN 2012103178736A CN 201210317873 A CN201210317873 A CN 201210317873A CN 102830221 A CN102830221 A CN 102830221A
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- cuvette
- stepper motor
- rotation
- connecting link
- lifting body
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Abstract
The invention relates to a mixing device of an automatic biochemical analyzer, which relates to the technical field of the automatic biochemical analyzer. The mixing device solves the technical disadvantage that in the prior art, a stirring rod is used for directly inserting in a cuvette for rotating with high speed to mix a sample and a reagent to obtain the detection results which have errors easily, the mixing device is characterized in that a cuvette holding groove used for holding the cuvette is provided below a reaction plate, corresponding to the position of a cuvette cup hole, a connecting rod is connected at the bottom of the cuvette holding groove, a driving mechanism is connected to the bottom of the connecting rod, and the driving mechanism is mainly composed of a rotation stepping motor used for driving the rotation of the connecting rod and a lifting-up mechanism used for driving the elevation of the connecting rod. According to the invention, the lifting and rotation of the cuvette holding groove can be used for holding the cuvette filled with the sample and the reagent from a fixed hole on the reaction plate, then the rotary stirring is carried out, relative to a current stirring mode, the sample and the reagent can be mixed without contact with a solution, thereby the cross contamination of the solution can be avoided, bubbles can not generate, the light scattering caused by bubble can be avoided, and the detection result has high accuracy.
Description
Technical field
The present invention relates to the automatic clinical chemistry analyzer technical field, be specifically related to sample and the well-mixed device of reagent aspect that automatic clinical chemistry analyzer inside is used for the contrast colors cup.
Background technology
Automatic clinical chemistry analyzer is one of important analysis instrument that often uses in the clinical examination, and it is through measuring various biochemical indicators to the analysis of blood or other body fluid, so that scientific basis is provided for diagnosis and definite patient's state of an illness.
In automatic clinical chemistry analyzer, mixing arrangement is essential.The effect of mixing arrangement is to make sample and reagent in the cuvette fully mix.
The mixing arrangement that adopts in the automatic clinical chemistry analyzer at present all adopts stirring apparatus, and stirring rod is directly inserted high speed rotating behind the cuvette, makes sample and reagent fully mix.This mode can make and produce bubble in the cuvette, and the liquid that adheres on the stirring rod can cause cross pollution, and these 2 shortcomings all can make testing result produce error.Common improving one's methods added non-sticking lining or added an independent Butterworth Hatch to stirring rod to stirring rod, and these methods had both increased cost, can not eliminate error fully again.
Summary of the invention
In sum; The objective of the invention is to solve and existingly adopt stirring rod directly to insert the mode of high speed rotating behind the cuvette to carry out the mode of mixing sample and reagent and exist testing result to occur the technical deficiency of error easily, and the mixing arrangement of a kind of automatic clinical chemistry analyzer of proposition.
For solving technical matters proposed by the invention; The technical scheme that adopts is: a kind of mixing arrangement of automatic clinical chemistry analyzer; It is characterized in that: comprise that being located at the reaction tray below is provided with the holder cup groove that is used to lift cuvette with position, cuvette hole correspondence position; The bottom of holder cup groove is provided with connecting link, and the connecting link bottom is connected with driving mechanism; Described driving mechanism mainly is made up of rotation stepper motor that drives the connecting link rotation and the lifting body that drives the connecting link up-down.
Described connecting link directly is fixedly connected with the rotation stepper motor; Lifting body is located at rotation stepper motor bottom.
Described lifting body includes the guiding mechanism that flexibly connects the rotation stepper motor and the cylinder or the linear electric motors that are used for jacking rotation stepper motor.
Described lifting body includes guiding mechanism and the jacking stepper motor that flexibly connects the rotation stepper motor; Described jacking stepper motor is connected with the rotation stepper motor through screw rod.
Described driving mechanism is located at the constant temperature enclosure outside, and connecting link is provided with the seal of the through hole lubrication and seal of offering with the constant temperature enclosure bottom.
The degree of depth of described holder cup groove is 1/2 to 1/5 of a cuvette height, and bore be and identical square of cuvette.
Described lifting body is located between connecting link and the rotation stepper motor; Described lifting body comprises a screw rod that is connected with connecting link and a nut that is socketed on the screw rod; Dock with the driving shaft of rotation stepper motor is movable through non-round connection-peg said screw rod bottom, and nut is connected with rotation stepper motor relative fixed.
Beneficial effect of the present invention is: the present invention adopts upward lifting of holder cup groove and rotation will be equipped with the fixed orifice of cuvette on reaction tray of sample and reagent and holds up; Be rotated stirring then; With respect to existing alr mode; When biased sample and reagent, need not contact solution, avoided the cross pollution of solution; Simultaneously can not produce bubble, avoid bubble to scattering of light, the testing result accuracy rate is high.
Description of drawings
Fig. 1 has lifted the structural representation of cuvette before the time for embodiments of the invention 1 holder cup groove;
Structural representation when Fig. 2 has lifted cuvette for embodiments of the invention 1 holder cup groove;
Fig. 3 has lifted the structural representation of cuvette before the time for embodiments of the invention 2 holder cup grooves;
Structural representation when Fig. 4 has lifted cuvette for embodiments of the invention 2 holder cup grooves.
Embodiment
Below in conjunction with accompanying drawing and the preferred two kinds of embodiment of the present invention structure of the present invention is done explanation further.
Shown in seeing figures.1.and.2; Constant temperature enclosure 1 inside of automatic clinical chemistry analyzer is provided with reaction tray 2, and reaction tray 2 is claimed traffic cycle again, and being circle distribution on the reaction tray 2 has several cuvette holes; Can place a cuvette 3 in each cuvette hole; Cuvette hole on the reaction tray 2 is circular, the cup body and the cuvette hole hole wall clearance fit of cuvette 3, and the outer that cuvette 3 turns up through opening part is suspended on the reaction tray 2.
The present invention includes holder cup groove 4, connecting link 5 and driving mechanism 6.A holder cup groove 4 is located at reaction tray 2 belows and position, cuvette hole correspondence position, and the degree of depth of holder cup groove 4 is 1/2 to 1/5 of cuvette 3 height, and bore is and identical square of cuvette; For unspecified angle is realized holder cup groove 4 and cuvette 3 sockets; The bore of holder cup groove 4 can be funnel-form, and holder cup groove 4 is used for upwards having lifted cuvette 3, after cuvette 3 is suitably lifted; Break away from the restriction in the cuvette hole on the reaction tray 2, can free rotation.Connecting link 5 tops are fixedly connected with the bottom centre of holder cup groove 4; Connecting link 5 bottoms connect driving mechanism 6 again; Driving mechanism 6 preferably is located at constant temperature enclosure 1 outside; Connecting link 5 is drawn the back from the diapire of constant temperature enclosure 1 and is connected driving mechanism 6, is full of not volatile lubricating fluid between the diapire fairlead of connecting link 5 and constant temperature enclosure 1, neither influences the impermeability that connecting link 5 rotates and moved up and down and protected constant temperature enclosure.Driving mechanism 6 mainly is made up of rotation stepper motor that drives connecting link 5 rotations 61 and the lifting body 62 that drives connecting link 5 up-downs.
Described connecting link 5 directly is fixedly connected with rotation stepper motor 61, and during 61 work of rotation stepper motor, connecting link 5 forward rotations or reverse rotation that is to say to drive 4 rotations of holder cup groove; Lifting body 62 is located at rotation stepper motor 61 bottoms, and lifting body 62 includes the guiding mechanism 621 that flexibly connects rotation stepper motor 61 and the cylinder or the linear electric motors 622 that are used for jacking rotation stepper motor 61; In the practical implementation process, lifting body 62 can certainly adopt guiding mechanism and jacking stepper motor to constitute, and the jacking stepper motor is connected with rotation stepper motor 61 through screw rod.
The course of work of the present invention is: under the driving of reaction tray 2; The cuvette that has added sample and reagent 3 is gone to position directly over the holder cup groove 4; Lifting body 62 is carried out the jackings operation then, and rotation stepper motor 61, connecting link 5 and holder cup groove 4 rise, holder cup groove 4 with cuvette 3 outers from the cuvette hole of reaction tray 2 break away from fixing after; Rotation stepper motor 61 fast rotational; Drive cuvette 3 quick rotations through connecting link 5 and holder cup groove 4, the solution in the cuvette 3 is flowed fast, thereby sample and reagent are fully mixed; After mixing finished, rotation stepper motor 61 stopped the rotation lentamente, made cuvette 3 recover rotation angle before; Then, lifting body 62 resets, and holder cup groove 4 descends, and cuvette 3 returns to the cuvette hole of reaction tray 2 and fixes, and takes cuvette 3 away by reaction tray 2 rotations, and operation is accomplished.
Shown in Fig. 3 and Fig. 4, when cuvette 3 xsects are circle, consider the cost problem of lifting body 62 ', described lifting body 62 ' is located between connecting link 6 and the rotation stepper motor 61; Described lifting body 62 ' comprises a screw rod 621 ' that is connected with connecting link 5 and a nut 622 ' that is socketed on the screw rod 621 '; Dock with the driving shaft of rotation stepper motor 61 is movable through non-round connection-peg 623 ' said screw rod 621 ' bottom, and nut 622 ' is connected with rotation stepper motor 61 relative fixed.
In the present embodiment, the principle of work of lifting body 62 ' is: when just changeing like rotation stepper motor 61, under the cooperation of screw rod 621 ' and nut 622 '; Connecting link 5 rises; After the threaded portion of screw rod 621 ' produced from nut 622 ' fully, threaded portion lost with nut and cooperates, under the situation that rotation stepper motor 61 continues just changeing; Connecting link 5 stops to rise, and holder cup groove 4 has been lifted cuvette 3 rotations; When 61 counter-rotatings of rotation stepper motor, the threaded portion of screw rod 621 ' gets in the nut 622 ' again, and connecting link 5 advances downwards, and cuvette 3 descends and resets, and screw rod 621 ' threaded portion need not from nut, to come off.
Claims (7)
1. the mixing arrangement of an automatic clinical chemistry analyzer is characterized in that: comprise that being located at the reaction tray below is provided with the holder cup groove that is used to lift cuvette with position, cuvette hole correspondence position, the bottom of holder cup groove is provided with connecting link, and the connecting link bottom is connected with driving mechanism; Described driving mechanism mainly is made up of rotation stepper motor that drives the connecting link rotation and the lifting body that drives the connecting link up-down.
2. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 1, it is characterized in that: described connecting link directly is fixedly connected with the rotation stepper motor; Lifting body is located at rotation stepper motor bottom.
3. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2 is characterized in that: described lifting body includes the guiding mechanism that flexibly connects the rotation stepper motor and the cylinder or the linear electric motors that are used for jacking rotation stepper motor.
4. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2 is characterized in that: described lifting body includes guiding mechanism and the jacking stepper motor that flexibly connects the rotation stepper motor; Described jacking stepper motor is connected with the rotation stepper motor through screw rod.
5. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2, it is characterized in that: described driving mechanism is located at the constant temperature enclosure outside, and connecting link is provided with the seal of the through hole lubrication and seal of offering with the constant temperature enclosure bottom.
6. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2 is characterized in that: the degree of depth of described holder cup groove is 1/2 to 1/5 of a cuvette height, and bore be and identical square of cuvette.
7. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 1, it is characterized in that: described lifting body is located between connecting link and the rotation stepper motor; Described lifting body comprises a screw rod that is connected with connecting link and a nut that is socketed on the screw rod; Dock with the driving shaft of rotation stepper motor is movable through non-round connection-peg said screw rod bottom, and nut is connected with rotation stepper motor relative fixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210317873.6A CN102830221B (en) | 2012-08-31 | 2012-08-31 | Mixing device of automatic biochemical analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210317873.6A CN102830221B (en) | 2012-08-31 | 2012-08-31 | Mixing device of automatic biochemical analyzer |
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| CN102830221A true CN102830221A (en) | 2012-12-19 |
| CN102830221B CN102830221B (en) | 2015-05-27 |
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| CN201210317873.6A Active CN102830221B (en) | 2012-08-31 | 2012-08-31 | Mixing device of automatic biochemical analyzer |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104076157A (en) * | 2014-07-15 | 2014-10-01 | 中国科学院苏州生物医学工程技术研究所 | Oscillation device |
| CN104555280A (en) * | 2014-12-31 | 2015-04-29 | 江苏安德信超导加速器科技有限公司 | Automatic sample changing device in radiation environment |
| CN105373763A (en) * | 2015-12-21 | 2016-03-02 | 艾康生物技术(杭州)有限公司 | Identity information reading device |
| CN105628945A (en) * | 2015-12-21 | 2016-06-01 | 利多(香港)有限公司 | Container rotating device and container rotating method |
| US10112781B2 (en) | 2017-03-01 | 2018-10-30 | Leadway (Hk) Limited | Container autorotation device and container autorotation method |
| CN110376393A (en) * | 2019-08-21 | 2019-10-25 | 东软威特曼生物科技（沈阳）有限公司 | The reaction tray and its automatic clinical chemistry analyzer of solid directly-heated structure |
| US11255846B2 (en) | 2017-03-01 | 2022-02-22 | Leadway (Hk) Limited | Reagent mixing and conveying device and reagent mixing method |
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| JPH04130248A (en) * | 1990-09-21 | 1992-05-01 | Hitachi Ltd | Biochemical automatic analyzer |
| CN1384361A (en) * | 2001-04-27 | 2002-12-11 | 刘岩 | Separate multi-channel biochemical analyzer |
| EP1544601A2 (en) * | 2003-12-19 | 2005-06-22 | Hitachi High-Technologies Corporation | Air bubbles removing system in an automatic analyzer |
| JP2005214683A (en) * | 2004-01-28 | 2005-08-11 | Hitachi High-Technologies Corp | Automatic analyzer |
| CN102419375A (en) * | 2011-08-24 | 2012-04-18 | 四川迈克生物科技股份有限公司 | Full-automatic chemoluminescence immunoassay analyzer |
| CN202837297U (en) * | 2012-08-31 | 2013-03-27 | 深圳市尚荣医疗股份有限公司 | Mixing device of fully automatic biochemical analyzer |
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2012
- 2012-08-31 CN CN201210317873.6A patent/CN102830221B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH04130248A (en) * | 1990-09-21 | 1992-05-01 | Hitachi Ltd | Biochemical automatic analyzer |
| CN1384361A (en) * | 2001-04-27 | 2002-12-11 | 刘岩 | Separate multi-channel biochemical analyzer |
| EP1544601A2 (en) * | 2003-12-19 | 2005-06-22 | Hitachi High-Technologies Corporation | Air bubbles removing system in an automatic analyzer |
| JP2005214683A (en) * | 2004-01-28 | 2005-08-11 | Hitachi High-Technologies Corp | Automatic analyzer |
| CN102419375A (en) * | 2011-08-24 | 2012-04-18 | 四川迈克生物科技股份有限公司 | Full-automatic chemoluminescence immunoassay analyzer |
| CN202837297U (en) * | 2012-08-31 | 2013-03-27 | 深圳市尚荣医疗股份有限公司 | Mixing device of fully automatic biochemical analyzer |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104076157A (en) * | 2014-07-15 | 2014-10-01 | 中国科学院苏州生物医学工程技术研究所 | Oscillation device |
| CN104555280A (en) * | 2014-12-31 | 2015-04-29 | 江苏安德信超导加速器科技有限公司 | Automatic sample changing device in radiation environment |
| CN105373763A (en) * | 2015-12-21 | 2016-03-02 | 艾康生物技术(杭州)有限公司 | Identity information reading device |
| CN105628945A (en) * | 2015-12-21 | 2016-06-01 | 利多(香港)有限公司 | Container rotating device and container rotating method |
| CN105628945B (en) * | 2015-12-21 | 2018-02-02 | 利多(香港)有限公司 | Container rotating device and container are from shifting method |
| CN105373763B (en) * | 2015-12-21 | 2018-04-24 | 艾康生物技术(杭州)有限公司 | Identity information reading device |
| US10112781B2 (en) | 2017-03-01 | 2018-10-30 | Leadway (Hk) Limited | Container autorotation device and container autorotation method |
| US11255846B2 (en) | 2017-03-01 | 2022-02-22 | Leadway (Hk) Limited | Reagent mixing and conveying device and reagent mixing method |
| CN110376393A (en) * | 2019-08-21 | 2019-10-25 | 东软威特曼生物科技（沈阳）有限公司 | The reaction tray and its automatic clinical chemistry analyzer of solid directly-heated structure |
| CN110376393B (en) * | 2019-08-21 | 2023-05-30 | 东软威特曼生物科技（沈阳）有限公司 | Reaction disc with solid direct-heating structure and full-automatic biochemical analyzer thereof |
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| Publication number | Publication date |
|---|---|
| CN102830221B (en) | 2015-05-27 |
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