CN102631736B - Dry powder suction device - Google Patents

Dry powder suction device Download PDF

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Publication number
CN102631736B
CN102631736B CN201110440225.5A CN201110440225A CN102631736B CN 102631736 B CN102631736 B CN 102631736B CN 201110440225 A CN201110440225 A CN 201110440225A CN 102631736 B CN102631736 B CN 102631736B
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CN
China
Prior art keywords
capsule
medicament
access unit
powder inhaler
collection unit
Prior art date
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Active
Application number
CN201110440225.5A
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Chinese (zh)
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CN102631736A (en
Inventor
梅兴国
孙思平
李志平
龚伟
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Institute of Pharmacology and Toxicology of AMMS
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Institute of Pharmacology and Toxicology of AMMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority to CN201110440225.5A priority Critical patent/CN102631736B/en
Publication of CN102631736A publication Critical patent/CN102631736A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0038Cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/004Details of the piercing or cutting means with fixed piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows

Abstract

The invention provides a dry powder suction device. The dry powder suction device (10) comprises a medicament suction part (20), a medicament dispersion part (50), a capsule gather and preservation part (30), a drawer-type capsule in-and-out part (40), a medicament capture and collection part (32), a capsule air supply part (60), an air circulation path (31) and cutters (70A and 70B), wherein the medicament dispersion part (50) is connected with the lower part of the medicament suction part (20); the capsule intake and preservation part (30) is arranged below the medicament dispersion part (50) and is used for gathering a capsule (K); the drawer-type capsule in-and-out part (40) can be pulled out of and pushed into the capsule gather and preservation part (30); the medicament capture and collection part (32) is used for capturing and collecting powdery medicaments; the medicament capture and collection part (32) is communicated with a hole (61) by virtue of the air circulation path (31); and the cutters (70A and 70B) are used for opening at capsule end parts (KA and KB) on two axial sides of the capsule (K). The dry powder suction device is easy to carry and simple and convenient to operate, can be reused and has the advantages of being simple in structure, convenient to process and low in cost; and by virtue of the dry powder suction device, the capsule evacuation rate is high.

Description

Powder inhaler
Technical field
The present invention relates to a kind of powder inhaler, more particularly, relate to the active suction apparatus of a kind of applicable direct oral cavity to pulmonary delivery mealy medicine.
Background technology
The feature of powder inhaler is: with Foradil Aerolizer formoterol fumarate (DPI) form administration, the capillary absorbance that medicine is abundant under pulmonary and respiratory mucosa, and onset quickly; People's lung surface is long-pending large, and alveolar surface is made up of adhesion, and medicine is through air. and the distance that blood exchanges is short, and speed is fast; Administration without gastrointestinal tract zymolysis, without first pass effect of hepar.Because enzymatic activity is lower, thin and the membrane permeability advantages of higher of epithelial barrier, thus the small-molecule drugs such as protein and peptide drugs administration, beta-adrenaline antagonist, cholilytic drug, 17-hydroxy-11-dehydrocorticosterone, potent narcotic, migraine are particularly useful for, and the macromolecular drugs such as insulin, growth hormone, vaccine and new biological technology products also can be made into formulation for pulmonary delivery, play local or whole body therapeutic effect.
The same MDI of DPI (quantitative atomized inhalation) compares has obvious advantage: patient initiatively sucks medicated powder, there is not administration coordinated problem; Non-freon propellant, avoids, to the pollution of atmospheric environment, not stimulating respiratory tract; Not containing the solvent such as ethanol and antiseptic, to pathological changes mucosa nonirritant; As solid dosage forms, be particularly suitable for Peptides and proteins; Not by the restriction of drug solubility, drug loading can be very high.
Clinical therapeutic effect directly depends on the difference of the internal combination mode of delivery device, the size, form, molecular weight, electric charge, moisture absorption etc. of drug particles.With regard to granular size, the drug particles that diameter is 1 ~ 5 μm is the most suitable, be referred to as inhalable particles, the granule the being greater than 5 μm then overwhelming majority is trapped within pars oralis pharyngis, finally enter in body through swallowing, and though the granule being less than 0.5 μm can reach lower respiratory tract, when tidal breath, the microgranule of 90% excretes with expiration again.
In recent ten years, due to the rise of the micronization technology such as spraying dry, supercritical fluid, multiple dose, gettering rate is required that low Novel medicine feeding device continues to bring out, DPI type and quantity increase rapidly, applicable types of drugs extends to the active drug of each link for the treatment of asthma by sodium cromoglicate originally, develop into compound preparation by single preparations of ephedrine, at present just by single treatment asthma drug to antibiotic, protein and peptide drugs, genomic medicine and Vaccine Development.
Powder inhaler huge number, according to dosage can be divided into: single dose, depot multiple dose, multiple units dosage; Can be divided into by the storing mode of medicine: capsule-type, vesicle type, depot; Can be divided into by the power resources of device: suction air-flow is driving, compressed air-driven type, cell motor are driving.
The shortcoming that now conventional powder inhaler exists is: volume is comparatively large, carries inconvenience; Use operation comparatively to bother, often need repairing; In device, drug residue is higher; Except single-dose type (as rotated inhaler etc.), all not reproducible use of all the other powder inhalers, causes patient's repeat buying suction apparatus, has increased the weight of patient treatment expense, brings unnecessary financial burden to patient.China is a large agricultural country, and the high medical apparatus and instruments of price is difficult to the approval obtaining peasant and low-income group, and this is not suitable for improving Medicare environment, wide popularization and application to popular current demand.Dosage form (all protecting) powder inhaler also also exists complex structure, cost is high for the multiple dose type of current use (standard receive device etc.) and storage, and raw material used is many, pollute the problems such as large.
Summary of the invention
The invention provides a kind of powder inhaler, its goal of the invention is to solve above problems of the prior art.
Powder inhaler of the present invention comprises: upper end open forms the medicament sucting of medical agent inhalation port; Medicament through part, it is connected to the below of medicament sucting; Capsule storage maintaining part, it is located at the below of medicament through part, for receiving the capsule keeping being filled with mealy medicine; Capsule access unit, it is arranged to the drawer type that can pull out, push capsule storage maintaining part; Collection unit caught by medicament, and it is positioned at the below of the capsule access unit being pushed into capsule storage maintaining part, for catching, collecting mealy medicine; Capsule gas supply part, itself and medicament are caught collection unit and are connected and are provided with one or more hole, for suck time from the external world to air supply in capsule; Air flow path, medicament is caught collection unit and is communicated with hole by it, thus forms the circulation path that collection unit caught by outside air arrival medicament; Cutter, it is arranged on the both sides up and down of capsule storage maintaining part, and utilize capsule access unit push action, open-ended at the capsule of the axial both sides of capsule.
Preferably, in powder inhaler of the present invention, described capsule access unit is provided with the capsule removable recess for removable capsule.
Preferably, in powder inhaler of the present invention, the drawer end of described capsule access unit contacts with the protuberance being arranged at described capsule and receiving maintaining part, spacing described capsule access unit when forming the described capsule access unit of pull-out and the structure of not deviating from.
Preferably, in powder inhaler of the present invention, the contact surface that maintaining part received by the protruding end of described capsule access unit and described capsule abuts against, and forms the spacing structure blocking described capsule access unit when pushing described capsule access unit.
Preferably, in powder inhaler of the present invention, described medicament through part is provided with one or more tangential admission mouth.
Preferably, in powder inhaler of the present invention, collection unit caught by described medicament is concavity pallet.
Preferably, in powder inhaler of the present invention, the inner chamber of described medicament sucting and outer wall shape are circular or oval.
Preferably, in powder inhaler of the present invention, described capsule gas supply part is caught collection unit around described medicament and is provided with 4 circular holes.
According to powder inhaler of the present invention, it is easy to carry about with one, easy and simple to handle, and capsule Emptying Rate is high, reusable, has structure simple, easy to process, cheap advantage.
Accompanying drawing explanation
With reference to accompanying drawing, feature of the present invention and advantage thereof will become clearer, wherein:
Fig. 1 is the side view of the embodiment representing powder inhaler of the present invention.
Fig. 2 is the profile of the embodiment representing powder inhaler of the present invention.
Fig. 3 represents in fig. 2, pulls out capsule access unit, placed the profile of encapsulated state.
Fig. 4 represents in fig. 2, and in the process capsule access unit that placed capsule being pushed capsule storage maintaining part, cutter is cutting off the profile of the state of capsule end.
Fig. 5 represents in fig. 2, and capsule end is cut off by cutter, completes perforate, and the medicament in capsule catches to medicament that collection unit falls, the profile of reverse flow state.
Fig. 6 represents that medicament is sent capsule, carries out the profile of the state sucked by after initiatively sucking air-flow.
Detailed description of the invention
With reference to the accompanying drawings the specific embodiment of the present invention is described in detail.These detailed description of the invention are preferred version of the present invention, are not construed as limiting the invention.
One embodiment of the present of invention are described in detail based on Fig. 1 ~ Fig. 6.Fig. 1 is the side view of the embodiment of powder inhaler of the present invention, and Fig. 2 is the side cut away view of the powder inhaler representing the present embodiment.
As can be seen from Fig. 1 ~ 2, powder inhaler 10 comprises substantially: receive for mouth and suck the medicament sucting 20 of medicament, its upper end open forms medical agent inhalation port 21; Medicament through part 50, it is connected with medicament sucting 20, can arrange one or more tangential admission mouth 51 at this medicament through part 50 place; Capsule storage maintaining part 30, it is positioned at below medicament through part 50, for receiving the capsule K keeping being filled with mealy medicine; Capsule access unit 40, it is arranged to pull out the drawer type pushing capsule storage maintaining part 30, is provided with the capsule removable recess 41 of the capsule K for blocking loading in this capsule access unit 40; Collection unit 32 caught by medicament, and it is positioned at the below of the capsule access unit 40 be pushed into, for catching collection mealy medicine; Capsule gas supply part 60, itself and medicament are caught collection unit 32 and are connected, and are provided with one or more hole 61, for capsule K air supply; Air flow path 31, it is positioned at medicament and catches the top of collection unit 32 and catch collection unit 32 with this medicament and hole 61 is communicated with, and enters for the formation of outside air the air circulation path that collection unit 32 caught by medicament; Cutter 70A, 70B, it is positioned at the both sides up and down of capsule storage maintaining part 30, and what utilize capsule access unit 40 pushes action, at capsule end KA, KB opening of the axial both sides of capsule K.
Specifically, as shown in Figure 2, the inner chamber of medicament sucting 20 and outer wall shape can be circular or oval.The axially downside (air inflow side) that collection unit 32 is positioned at capsule K caught by medicament, and is constructed to concavity pallet, falls, the mealy medicine of adverse current for catching, collecting from capsule K.Capsule gas supply part 60 is caught collection unit 32 around medicament and is provided with 4 circular holes 61, the entrance that supply in capsule, air flows into.Air flow path 31 is positioned at medicament and catches above collection unit 32, and its one end is stretched into medicament a little and caught in collection unit 32, and this air flow path 31 and medicament are caught between collection unit 32 and also maintained certain gap.
As shown in Figure 3, capsule access unit 40 has capsule removable recess 41 in the position of removable capsule K, when capsule access unit 40 is drawn out, blocks capsule K by capsule removable recess 41, thus installs capsule K.Capsule end KA, KB of the axial both sides of capsule K are outstanding from these capsule removable recess 41 both sides respectively.This capsule access unit 40 can receive maintaining part 30 at the capsule that is transversely drawn out and pushes of the axis of opposed capsule K (above-below direction namely in figure).
Contacted with the protuberance 34 being arranged on capsule and receiving maintaining part 30 by the drawer end 43 of capsule access unit 40, when forming pull-out capsule access unit 40, capsule access unit 40 is carried out spacing and structure that is that do not deviate from.In addition, when capsule access unit 40 being pushed capsule storage maintaining part 30, because protruding end 42A, 42B of capsule access unit 40 contact with the contact surface 33 that maintaining part 30 received by capsule, form this capsule access unit 40 when pushing capsule access unit 40 and be blocked and spacing structure.
The powder inhaler of the present embodiment is as above-mentioned formation.Below, based on Fig. 3 ~ Fig. 5, illustrate that capsule K is by action during perforate.
First, as shown in Figure 3, capsule K is placed in the capsule removable recess 41 of capsule access unit 40, promotes the capsule access unit end face 44 of capsule access unit 40, capsule access unit 40 is pushed in capsule storage maintaining part 30.
And then, as shown in Figure 4, along with the capsule K be placed in the capsule removable recess 41 of capsule access unit 40 enters capsule storage maintaining part 30, utilize be positioned at capsule storage maintaining part 30, at cutter 70A, 70B of being transversely located at the axial both sides of capsule K respectively of opposed capsule K axis, cut off capsule end KA, KB of the axial both sides of capsule K, like this, capsule K axially two STHs.
Continue the capsule access unit end face 44 promoting capsule access unit 40, contacted with the contact surface 33 that maintaining part received by capsule by protruding end 42A, 42B, the capsule K having completed perforate in axial both sides is done feeding, now this capsule K is communicated with capsule storage maintaining part 30, capsule gas supply part 60, medicament through part 50 and medicament sucting 20, thus formation path, complete the preparation before suction.
Now, as shown in Figure 5, although make the medicament in the capsule K of axial both sides by perforate fall due to the existence of air flow path 31, these medicaments are caught collection unit 32 by the medicament of lower end and are caught collection.
Below, illustrate after carrying out perforate to capsule K based on Fig. 6, user sucks action during medicament.Arrow in Fig. 6 indicates air-flow direction.
First, user was breathed out as possible and emptying pulmonary air before use powder inhaler 10, and stretch in user mouth by the medicament sucting 20 of powder inhaler 10, user mouth is received and contained this medicament sucting 20.Secondly, as shown in Figure 6, user FI, thus, medicament sucting 20, medicament through part 50, capsule K are inner, collection unit 32 caught by medicament and capsule gas supply part 60 forms negative pressure, and portion of air is entered by capsule gas supply part 60, arrive medicament through air flow path 31 and catch collection unit 32, now kicked up by mealy medicine, mealy medicine flows to into capsule K with inhaling air, enters medicament through part 50 further.
In addition, portion of air enters medicament through part 50 internal cavities by two tangential admission mouths 51 of medicament through part 50.Because medicament through part 50 is shorter to the distance of medical agent inhalation port 21 than capsule gas supply part 60 to the distance of medical agent inhalation port 21, therefore before mealy medicine enters medicament through part 50, in its internal cavities, more first form vortex shape turbulent flow.When mealy medicine enters medicament through part 50, mealy medicine disperses along with vortex shape ascending air, be able to better atomization, enter into medicament sucting 20 (if mealy medicine carrier model, along with vortex shape air-flow, under centrifugal action, medicine and carrier are owing to being subject to different centrifugal force, and the less medicine of quality separates from the carrier surface that quality is larger; If mealy medicine no-load build, under the effect of turbulent flow, the medicine of gathering is able to depolymerization again, thus aerosol dispersion).
Under suction airflow function, mealy medicine is inhaled in oral cavity along medicament sucting 20, and peroral delivery is to pulmonary.
In the powder inhaler of the present embodiment, owing to capsule K being placed in the capsule removable recess 41 of capsule access unit 40, along with capsule access unit being pushed in capsule storage maintaining part 30, utilize in capsule storage maintaining part 30, be located at the axial both sides of capsule K in the horizontal cutter 70A, 70B, cut off capsule end KA, KB of the axial both sides of capsule K, thus, at axially two STHs of capsule K, therefore, only need with less action capsule K being housed in powder inhaler 10, just can complete collecting and the perforate of capsule K.Need not worry to be separated into monomer as prior art and cause perforate lid and point lose, in addition, also can not cause owing to forgetting perforate action inhalation failure, can really complete while capsule K perforate inhalation preparation.
In addition, due in capsule storage maintaining part 30, arrange in air flow path 31 lower end catch collect fall from capsule K, the medicament of the mealy medicine of adverse current catches collection unit 32, thus, when perforate, mealy medicine is caught collection unit 32 by medicament and is caught, collects.Be stored in the medicament that medicament catches collection unit 32 and air flow path 31, transport by initiatively sucking air-flow, can be admitted to the oral cavity of user together with the mealy medicine in capsule K, peroral delivery is to pulmonary.Thus the medicament of filling in capsule K can be realized to carry out administration by ormal weight.
Although describe in detail by reference to the accompanying drawings above according to powder inhaler of the present invention; but foregoing description is also nonrestrictive; those skilled in the art can carry out suitable change to this powder inhaler on the basis of above-mentioned disclosure; such as change use material, change some detailed structure etc., but this also all drops within protection scope of the present invention.

Claims (6)

1. a powder inhaler, is characterized in that, this powder inhaler comprises:
Upper end open forms the medicament sucting (20) of medical agent inhalation port (21);
Medicament through part (50), it is connected to the below of medicament sucting (20);
Capsule storage maintaining part (30), it is located at the below of medicament through part (50), keeps capsule (K) for receiving;
Capsule access unit (40), it is arranged to the drawer type that can pull out, push capsule storage maintaining part (30);
Collection unit (32) caught by medicament, it is positioned at the below of the capsule access unit (40) being pushed into capsule storage maintaining part (30), for catching, collecting mealy medicine, described medicament catches collection unit (32) for concavity pallet;
Capsule gas supply part (60), itself and medicament are caught collection unit (32) and are connected and are provided with one or more hole (61), for suck time from the external world to air supply in capsule (K);
Air flow path (31), medicament is caught collection unit (32) and is communicated with hole (61) by it, thus forms the circulation path that collection unit (32) caught by outside air arrival medicament; With
Cutter (70A, 70B), it is arranged on the both sides up and down of capsule storage maintaining part (30), and what utilize capsule access unit (40) pushes action, carry out opening in the capsule end (KA, KB) of the axial both sides of capsule (K)
To be pushed into and described capsule (K) by opening is communicated with described capsule storage maintaining part (30), described capsule gas supply part (60), described medicament through part (50) and described medicament sucting (20), thus form the path sucked for medicament
Described medicament through part (50) is provided with one or more tangential admission mouth (51),
Described air flow path (31) is positioned at described medicament and catches collection unit (32) top, one end of described air flow path (31) is stretched into described medicament and is caught in collection unit (32), and described air flow path (31) and described medicament are caught between collection unit (32) and maintained certain gap.
2. powder inhaler as claimed in claim 1, it is characterized in that, described capsule access unit (40) is provided with the capsule removable recess (41) for removable capsule (K).
3. powder inhaler as claimed in claim 1 or 2, it is characterized in that, the drawer end (43) of described capsule access unit (40) contacts with the protuberance (34) being arranged at described capsule and receiving maintaining part (30), spacing described capsule access unit (40) when forming pull-out described capsule access unit (40) and the structure of not deviating from.
4. powder inhaler as claimed in claim 1 or 2, it is characterized in that, the contact surface (33) that maintaining part (30) received by the protruding end (42A, 42B) of described capsule access unit (40) and described capsule abuts against, and forms the spacing structure blocking described capsule access unit (40) when pushing described capsule access unit (40).
5. powder inhaler as claimed in claim 1, is characterized in that, the inner chamber of described medicament sucting (20) and outer wall shape are circular or oval.
6. powder inhaler as claimed in claim 1, is characterized in that, described capsule gas supply part (60) is caught collection unit (32) around described medicament and is provided with 4 circular holes (61).
CN201110440225.5A 2011-02-14 2011-12-26 Dry powder suction device Active CN102631736B (en)

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CN201110038610.7 2011-02-14
CN2011100386107 2011-02-14
CN201110038610 2011-02-14
CN201110440225.5A CN102631736B (en) 2011-02-14 2011-12-26 Dry powder suction device

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CN102631736B true CN102631736B (en) 2015-03-11

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105107070B (en) * 2015-09-23 2016-05-18 石家庄鑫富达医药包装有限公司 A kind of capsule type dry powder inhaler
CN113117193B (en) * 2021-04-20 2024-02-06 苏州新劢德医疗器械科技有限公司 Inhalation device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5752505A (en) * 1996-03-21 1998-05-19 Unisia Jecs Corporation Inhalation-type medicine delivery device
CN1215999A (en) * 1997-01-30 1999-05-05 尤尼夏·杰克斯株式会社 Suction type medicator
CN100515511C (en) * 2003-10-09 2009-07-22 株式会社;生命科学活效 Powdery medicine dispensing device for nasal cavity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000217917A (en) * 1999-01-27 2000-08-08 Unisia Jecs Corp Inhaler type medicine administration tool
CN2865724Y (en) * 2006-01-26 2007-02-07 上海华拓医药科技发展有限公司 Powder vapor inhalator
US7806117B2 (en) * 2006-06-07 2010-10-05 Shin Nippon Biomedical Laboratories, Ltd. Peroral powder delivery device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5752505A (en) * 1996-03-21 1998-05-19 Unisia Jecs Corporation Inhalation-type medicine delivery device
CN1215999A (en) * 1997-01-30 1999-05-05 尤尼夏·杰克斯株式会社 Suction type medicator
CN100515511C (en) * 2003-10-09 2009-07-22 株式会社;生命科学活效 Powdery medicine dispensing device for nasal cavity

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Inventor after: Mei Xingguo

Inventor after: Xie Xiangyang

Inventor after: Sun Siping

Inventor after: Li Zhiping

Inventor after: Gong Wei

Inventor after: Yang Yang

Inventor after: Yu Fanglin

Inventor after: Zhang Hui

Inventor after: Li Ying

Inventor after: Wang Zhiyuan

Inventor before: Mei Xingguo

Inventor before: Sun Siping

Inventor before: Li Zhiping

Inventor before: Gong Wei

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: MEI XINGGUO SUN SIPING LI ZHIPING GONG WEI TO: MEI XINGGUO SUN SIPING LI ZHIPING GONG WEI YANG YANG YU FANGLIN ZHANG HUI LI YING WANG ZHIYUAN XIE XIANGYANG