CN102631445A - Traditional Chinese medicine (TCM) for treating chronic hepatitis - Google Patents
Traditional Chinese medicine (TCM) for treating chronic hepatitis Download PDFInfo
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- CN102631445A CN102631445A CN2012100957714A CN201210095771A CN102631445A CN 102631445 A CN102631445 A CN 102631445A CN 2012100957714 A CN2012100957714 A CN 2012100957714A CN 201210095771 A CN201210095771 A CN 201210095771A CN 102631445 A CN102631445 A CN 102631445A
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- 239000003814 drug Substances 0.000 title claims abstract description 24
- 208000006454 hepatitis Diseases 0.000 title claims abstract description 14
- 206010008909 Chronic Hepatitis Diseases 0.000 title claims abstract description 13
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 12
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 12
- 241000222336 Ganoderma Species 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 22
- 239000000843 powder Substances 0.000 claims description 17
- 239000002775 capsule Substances 0.000 claims description 16
- 230000008569 process Effects 0.000 claims description 16
- 239000000284 extract Substances 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- 241000222640 Polyporus Species 0.000 claims description 11
- 238000007560 sedimentation technique Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 238000003809 water extraction Methods 0.000 claims description 3
- 230000006837 decompression Effects 0.000 claims description 2
- 230000008021 deposition Effects 0.000 claims description 2
- 150000004676 glycans Chemical class 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 229920001282 polysaccharide Polymers 0.000 claims description 2
- 239000005017 polysaccharide Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 16
- 239000008280 blood Substances 0.000 abstract description 13
- 210000004369 blood Anatomy 0.000 abstract description 13
- 230000017531 blood circulation Effects 0.000 abstract description 5
- 238000005728 strengthening Methods 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 3
- 230000003213 activating effect Effects 0.000 abstract description 2
- 208000010643 digestive system disease Diseases 0.000 abstract description 2
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 244000171085 Polyporus umbellatus Species 0.000 abstract 1
- 235000004837 Polyporus umbellatus Nutrition 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 description 10
- 230000002440 hepatic effect Effects 0.000 description 5
- 230000036039 immunity Effects 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 206010019668 Hepatic fibrosis Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241000207961 Sesamum Species 0.000 description 3
- 235000003434 Sesamum indicum Nutrition 0.000 description 3
- 208000019790 abdominal distention Diseases 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- AXONCVPTTFHNOI-UHFFFAOYSA-N kairine Chemical compound C1=CC(O)=C2N(C)CCCC2=C1 AXONCVPTTFHNOI-UHFFFAOYSA-N 0.000 description 3
- 230000003908 liver function Effects 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 102000007562 Serum Albumin Human genes 0.000 description 2
- 108010071390 Serum Albumin Proteins 0.000 description 2
- 102000003929 Transaminases Human genes 0.000 description 2
- 108090000340 Transaminases Proteins 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 229940126678 chinese medicines Drugs 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
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- 238000002474 experimental method Methods 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000000419 Chronic Hepatitis B Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 241000700721 Hepatitis B virus Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
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- 231100000283 hepatitis Toxicity 0.000 description 1
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- 230000002443 hepatoprotective effect Effects 0.000 description 1
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- 238000001727 in vivo Methods 0.000 description 1
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- 210000003734 kidney Anatomy 0.000 description 1
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- 208000019423 liver disease Diseases 0.000 description 1
- 238000007449 liver function test Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
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Abstract
The invention provides a traditional Chinese medicine (TCM) for treating chronic hepatitis, belonging to the field of TCMs for treating digestive system diseases. The TCM has good effect and quick effect. The TCM is prepared from the following raw materials: radix sophorae tonkinensis, largehead atractylodes rhizome, lucid ganoderma, radix notoginseng, salvia miltiorrhiza, polyporus umbellatus, immature tangerine peel and the like, has the functions of strengthening the body resistance, invigorating qi and nourishing blood, clearing away heat and removing toxicity, activating blood circulation to dissipate blood stasis and relieving pain and has the advantages of obvious effect, confirmed efficacy and quicker effect.
Description
Technical field
The invention belongs to the field of Chinese medicines of treatment digestive system disease.
Background technology
The present field of Chinese medicines that is intended to treat chronic hepatitis, the deficiency of two aspects of existence: the one, effect is obvious inadequately, and the 2nd, it is slower to take effect.So that large quantities of chronic hepatitis patients are because of can not get the treatment of active drug; Liver disease constantly develops, and clinical symptoms can not get alleviating, and the patient is seriously weak for a long time, dull pain in liver, liver function decline, hepatic fibrosis etc.; Life quality descends greatly, and I and family members are dissatisfied to this.
To problem set forth above, the present invention provides a kind of Chinese medicine of treating chronic hepatitis, and it is obvious inadequately that it can solve in this type of treatment by Chinese herbs in the past effect; The slower problem that takes effect, effective, instant effect, it is remarkable to have effect; Drug effect is definite, the advantage of quick result.
Summary of the invention
The present invention realizes through following technical scheme:
1, a kind of Chinese medicine of treating chronic hepatitis adopts the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:
Radix Sophorae Tonkinensis 3---18 parts of 9 parts of Rhizoma Atractylodis Macrocephalaes 3---9 portions of Ganodermas 6---
Radix Notoginseng 1---18 parts of 3 parts of Radix Salviae Miltiorrhizaes 6---18 portions of Polyporus 6---
Pericarpium Citri Reticulatae Viride 3---9 parts
The Chinese medicine of this treatment chronic hepatitis is processed by following method:
(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is following: Ganoderma is broken into graininess, crosses 40 mesh sieves
→Hot water (95 ℃) lixiviate with 1:20
→Lixiviating solution decompression, concentrated
→95% ethanol with 3 times of volumes mixes, left standstill 10-12 hours, centrifugal
→Add 75% ethanol, the deposition polysaccharide
→Dry the ganoderan extract fine powder;
(2) by above-mentioned weight ratio, Radix Sophorae Tonkinensis, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Polyporus, Pericarpium Citri Reticulatae Viride are extracted through conventional water extraction process, process extractum, oven dry is pulverized, and gets the extract fine powder;
(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, process Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.
The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that the main diseases of chronic hepatitis B is because of being the heresy of epidemic disease poison at research, and promptly patient's hypoimmunity causes viral infection, outbreak inflammation, state of an illness delay, obstinate.Though under present technical conditions, still can't virus be driven away fully externally, remove totally, we can suppress it through enhancing human body immunity power, and the control virus replication reduces viral load, and this is the key of treatment primary disease.So we attach most importance to Fuzheng Jiedu, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling is taken good care of the liver spleen, Qinghua hot and humid ecchymosis.The maximum value of the present invention just is: it has captured difficult two " difficult problems " that heal of delay in the chronic hepatitis treatment---and the one, " dull pain in liver " that is difficult to overcome significantly alleviated even disappeared, and the 2nd, insoluble " hepatic fibrosis reverse " realizes basically or fully.This is that doctor and patient call expectation hope for many years again and again.Ganoderma, Rhizoma Atractylodis Macrocephalae the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, the pivotal role of outstanding immunity, the easing the affected liver nourishing the liver, the spleen invigorating activating the spleen, enhancing human body immunity power, " opposing " interaction energy of immunity effectively resists hepatitis B virus duplicating in vivo, reduces its quantity; Radix Salviae Miltiorrhizae, Radix Notoginseng passage, nourishing blood, promoting blood circulation, removing blood stasis and relieving pain is enriched blood with nourishing the liver and kidney, removes the stagnant heat of blood part, and " reparation " effect of immunity can be repaired impaired hepatic tissue and liver function; Be aided with the soothing the liver dispelling the stagnated QI of Pericarpium Citri Reticulatae Viride, rush down pain relieving clearly, to separate dull pain in liver; The Radix Sophorae Tonkinensis clearing heat, releasing toxin, removing swelling; The Polyporus promoting diuresis to eliminate damp pathogen, the diuretic hepatoprotective, the kind wet edema, the dysuria that hold of stopping of harnessing the river, modern pharmacological research, polyporusum bellatus have the hepatitis virus resisting effect.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and heat-clearing and toxic substances removing, the merit of promoting blood circulation, removing blood stasis and relieving pain, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.
The specific embodiment
Through following embodiment the present invention is done and to specify:
1, get following prescription (weight is unit by gram):
The Radix Sophorae Tonkinensis 300 gram Rhizoma Atractylodis Macrocephalaes 300 kairine sesames 600 grams
Radix Notoginseng 100 gram Radix Salviae Miltiorrhizaes 600 gram Polyporus 600 grams
Pericarpium Citri Reticulatae Viride 300 grams
Press predetermined weight, Ganoderma is extracted with decoction and alcohol sedimentation technique; With conventional water extraction process Radix Sophorae Tonkinensis, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Polyporus, Pericarpium Citri Reticulatae Viride are extracted, process extract fine powder 270 grams altogether, Radix Notoginseng is ground into fine powder; Mix with said extracted thing fine powder; Stir, process fine particle, the capsule of packing into No. 0; Process 1233 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.3 gram.
2, get following prescription (weight in grams is a unit):
The Radix Sophorae Tonkinensis 600 gram Rhizoma Atractylodis Macrocephalaes 600 kairine sesames 1100 grams
Radix Notoginseng 180 gram Radix Salviae Miltiorrhizaes 1100 gram Polyporus 1100 grams
Pericarpium Citri Reticulatae Viride 600 grams
By above-mentioned same method, process 2300 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.3 gram.
3, get following prescription (weight is unit by gram):
The Radix Sophorae Tonkinensis 900 gram Rhizoma Atractylodis Macrocephalaes 900 kairine sesames 1800 grams
Radix Notoginseng 270 gram Radix Salviae Miltiorrhizaes 1800 gram Polyporus 1800 grams
Pericarpium Citri Reticulatae Viride 900 grams
By above-mentioned same method, process 3600 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.3 gram.
4, get following prescription (by weight):
8 parts of 4 portions of Ganodermas of 4 parts of Rhizoma Atractylodis Macrocephalaes of Radix Sophorae Tonkinensis
8 parts of 8 portions of Polyporus of 1 part of Radix Salviae Miltiorrhizae of Radix Notoginseng
4 parts on Pericarpium Citri Reticulatae Viride
By above-mentioned same method, process Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.3 gram.
5, get following prescription (by weight):
15 parts of 7 portions of Ganodermas of 7 parts of Rhizoma Atractylodis Macrocephalaes of Radix Sophorae Tonkinensis
15 parts of 15 portions of Polyporus of 2 parts of Radix Salviae Miltiorrhizaes of Radix Notoginseng
7 parts on Pericarpium Citri Reticulatae Viride
By above-mentioned same method, process Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.3 gram.
Clinical data:
The present invention is an example with traditional Chinese medical science chronic hepatitis, through 19 routine clinical observations.Selecting the tcm diagnosis chronic hepatitis is standard: limb is soft weak, and is weak from head to foot; Poor appetite, abdominal distention, dyspepsia; Face is pitch-dark, hepatic face is arranged; Dull pain in liver; Hepatic fibrosis is serious; It is undesired that liver function transaminase continues, and other index such as plasma albumin, blood STB etc. are unusual.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 11 examples, women's 8 examples do not have other serious disease, and the age is 47 years old-79 years old, 61.1 years old mean age.
Efficacy determination:
1, produce effects: weak alleviation, on one's body energetically; Poor appetite, abdominal distention, dull pain in liver are obviously alleviated, and the hepatic region is comfortable; Hepatic face is taken on a new look to some extent, and it is pale that face becomes; The hepatic fibrosis inspection is obviously alleviated; Indexs such as liver function test transaminase, plasma albumin are obviously improved.
2, effective: weak solution, on one's body energetically, abdominal distention, poor appetite, hepatic face are alleviated to some extent.
3, invalid: the disease no change.
During clinical experiment, withdraw other medicines and health nutrient.Taking the Chinese medicinal capsule that the specific embodiment of the invention 2 is made, observed 6 months, is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.3 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 6 months after, symptom is obviously improved.19 philtrums of clinical experiment, produce effects 9 people, effective 8 people, invalid 2 people, total effective rate 89.4%.
Claims (1)
1. Chinese medicine of treating chronic hepatitis is characterized in that: said Chinese medicine is to adopt the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:
Radix Sophorae Tonkinensis 3---18 parts of 9 parts of Rhizoma Atractylodis Macrocephalaes 3---9 portions of Ganodermas 6---
Radix Notoginseng 1---18 parts of 3 parts of Radix Salviae Miltiorrhizaes 6---18 portions of Polyporus 6---
Pericarpium Citri Reticulatae Viride 3---9 parts
The Chinese medicine of this treatment chronic hepatitis is processed by following method:
(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is following: Ganoderma is broken into graininess, crosses 40 mesh sieves
→Hot water (95 ℃) lixiviate with 1:20
→Lixiviating solution decompression, concentrated
→95% ethanol with 3 times of volumes mixes, left standstill 10-12 hours, centrifugal
→Add 75% ethanol, the deposition polysaccharide
→Dry the ganoderan extract fine powder;
(2) by above-mentioned weight ratio, Radix Sophorae Tonkinensis, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Polyporus, Pericarpium Citri Reticulatae Viride are extracted through conventional water extraction process, process extractum, oven dry is pulverized, and gets the extract fine powder;
(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, process Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100957714A CN102631445A (en) | 2012-04-04 | 2012-04-04 | Traditional Chinese medicine (TCM) for treating chronic hepatitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100957714A CN102631445A (en) | 2012-04-04 | 2012-04-04 | Traditional Chinese medicine (TCM) for treating chronic hepatitis |
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| Publication Number | Publication Date |
|---|---|
| CN102631445A true CN102631445A (en) | 2012-08-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012100957714A Pending CN102631445A (en) | 2012-04-04 | 2012-04-04 | Traditional Chinese medicine (TCM) for treating chronic hepatitis |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102327358A (en) * | 2011-10-10 | 2012-01-25 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102379989A (en) * | 2011-08-14 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102379994A (en) * | 2011-09-27 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102379947A (en) * | 2011-07-29 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102389479A (en) * | 2011-09-03 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102389480A (en) * | 2011-09-16 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating hepatitis |
-
2012
- 2012-04-04 CN CN2012100957714A patent/CN102631445A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379947A (en) * | 2011-07-29 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102379989A (en) * | 2011-08-14 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102389479A (en) * | 2011-09-03 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102389480A (en) * | 2011-09-16 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating hepatitis |
| CN102379994A (en) * | 2011-09-27 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
| CN102327358A (en) * | 2011-10-10 | 2012-01-25 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating chronic hepatitis |
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Application publication date: 20120815 |