CN102579041B - Arrayed flexible electroencephalogram dry electrode capable of overcoming obstacle of hair and preparation method thereof - Google Patents
Arrayed flexible electroencephalogram dry electrode capable of overcoming obstacle of hair and preparation method thereof Download PDFInfo
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- CN102579041B CN102579041B CN201210028938.5A CN201210028938A CN102579041B CN 102579041 B CN102579041 B CN 102579041B CN 201210028938 A CN201210028938 A CN 201210028938A CN 102579041 B CN102579041 B CN 102579041B
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Abstract
An arrayed flexible electroencephalogram dry electrode capable of overcoming obstacle of hair and a preparation method thereof belong to the technical field of medicine and are used for acquiring electroencephalogram signals. The flexible electroencephalogram dry electrode comprises a base and a contactor array extending from the base, a conductive metal film layer is arranged on the surface of the flexible electroencephalogram dry electrode, the contactors can be plugged into hair to reach the germinative layer so as to acquire the electroencephalogram signals. The dry electrode with excellent flexibility can contact with scalp well and can acquire the electroencephalogram signals well by existing processes and mechanical structures of MEMS (micro-electromechanical systems). Compared with the conventional wet electrode, the dry electrode can be used for long-term detection of the electroencephalogram signals without the preparation step of skin. Besides dry electrode which is small and flexible has high comfortableness and safety, is convenient and quick in use, low in noise to the external, and capable of completing high-quantity recording of microvolt-electroencephalogram signals.
Description
Technical field
What the present invention relates to is a kind of device of biomedical sector, specifically a kind ofly can overcome arrayed flexible electroencephalogramdry dry electrode of obstacle of hair and preparation method thereof.
Background technology
Human tissue cell is always spontaneously constantly producing very faint bioelectric.The electrode that utilization is laid on scalp extracts the electrical activity of brain cell and is recorded on special paper after electroencephalograph amplifies, and draws figure, the curve of certain waveform, wave amplitude, frequency and position phase, is electroencephalogram.When cerebral tissue generation pathology or changing function, there is corresponding change in this curve, thereby for clinical diagnosis, curing the disease provides foundation.
In recent years, along with development and the maturation of MEMS (MEMS:Micro-Electro-Mechanical Systems) technology, the microsystem ranges of application such as microelectronic device and microsensor are constantly expanded, be widely used in the fields such as civilian, medical science, military affairs.Research in conjunction with MEMS technology brain electrode has obtained developing rapidly.
Traditional eeg signal acquisition equipment is based on wet electrode.User is being used before eeg signal acquisition equipment, must coating conductive paste, and to reduce the impact of horny layer on the EEG signals collecting.But smear conductive paste, need under stranger is auxiliary, carry out, need to take a long time, and wet conductive paste can not effectively gather brain electricity after dry, be unfavorable for gathering for a long time brain electricity.In the last few years, along with the development of Technology of Microelectrodes, there is dry electrode eeg signal acquisition equipment.This mode not only can overcome cuticular resistive, can also avoid smearing the inconvenience of conductive paste, and because the signal collecting is directly to extract from stratum germinativum, the signal effect that its signal collecting even collects than wet electrode eeg signal acquisition equipment is good.
For the dry electrode that gathers EEG signals, mainly there are two problems at present: the one, when gathering brain electricity, people's self hair is laid formation obstacle to brain electrode, be difficult to collect the EEG signals of hair zones, obstacle how to break through hair is a key issue.The 2nd, for gathering the dry electrode of brain electricity, be all rigidity, this is very uncomfortable concerning user, also user is existed to potential danger.
Find by prior art documents, Chin-Teng Lin, the people such as Lun-De Liao write articles " Novel Dry Polymer Foam Electrodes for Long-Term EEG Measurement " (" being applied to the dry electrode of the electrometric innovation foam of polymers of long term brain " < < IEEE biomedical engineering proceedings > >) at < < IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING > > 58 (2011) 1200-1207, this article is mentioned and is adopted the conductive foam that is square shape to make the dry electrode that can measure for a long time brain electricity, conductive foam softness, can be close to skin, use comfortable, eliminate the potential danger to human body of the electrode of hard material making.But for the brain wave acquisition of hair zones, the structure of electrode is difficult to overcome the obstacle of hair in this article, cannot effectively gather the EEG signals of hair zones.
Summary of the invention
For above-mentioned the deficiencies in the prior art and defect, the present invention proposes a kind ofly can overcome arrayed flexible electroencephalogramdry dry electrode of obstacle of hair and preparation method thereof, can be flexible and be the eeg signal acquisition for there being hair zones.This electrode can obtain reliable and stable EEG signals fast, solves and when gathering brain electricity, is subject to the problem that hair disturbs, the comfortableness and the safety that also improve brain electrode all the time simultaneously.
The present invention is achieved through the following technical solutions:
A kind of arrayed flexible electroencephalogramdry dry electrode that can overcome obstacle of hair, for the collection of EEG signals, the dry electrode of described flexible brain electricity comprises the feeler that is array stretching out on base and base, its surface has one deck conductive metal film, described feeler can insert hair, and the stratum germinativum that reaches skin carries out the collection of EEG signals.
The described dry electrode employing of flexible brain electricity has biocompatible polymeric material polydimethylsiloxane and makes.
The conductive metal film of the described dry electrode surface of flexible brain electricity is to obtain by MEMS (MEMS) PROCESS FOR TREATMENT.
A method of preparing the dry electrode of above-mentioned flexible brain electricity, comprises that step is as follows:
1) utilize the method for machining to make flexible dry electrode die;
2) polymeric material is cast in flexible dry electrode die after by pretreatment, after baking oven heat treatment, form pretreatment flexible dry electrode;
3), at pretreatment flexible dry electrode surface sputter one deck conductive metal film, can obtain having the dry electrode of flexible brain electricity of electric conductivity.
Described flexible dry electrode die comprises upper bolster, middle die holder and die shoe.
In above-mentioned preparation method, described flexible dry electrode die upper bolster is ring-type, and annular inner circle is utilized boring cutter processing.Interior diameter of a circle has determined the size of flexible dry electrodes base, and the height of mold determines the thickness of flexible dry electrodes base.
In above-mentioned preparation method, in described flexible dry electrode die, die holder is the through hole of array shape.Through hole utilizes drilling machine processing.The diameter in hole determines the size of the feeler of flexible dry electrode, and the height of middle die holder has determined the length of flexible dry electrode feeler.In design, during mould, in can increasing arbitrarily as required, the quantity of die holder is to change the length of feeler.
In above-mentioned preparation method, described flexible dry electrode die shoe has the circular hole with middle die holder identical array shape and quantity, and the circular hole of die shoe is blind hole.The design of die shoe is in order to be beneficial to the demoulding.
In above-mentioned preparation method, described polymeric material polydimethylsiloxane pretreatment is to pump bubble after prepolymerized polydimethylsiloxane and firming agent mass ratio are uniformly mixed at 10: 1.
In above-mentioned preparation method, described baking oven heat treatment refers in baking oven 70 ℃ of heat treatments 2 hours.
Described flexible dry electrode die can adopt nylon, rustless steel, aluminium.
Described flexible dry electrode is to do on the basis of pretreatment flexible dry electrode to utilize MEMS technique to make pretreatment flexible dry electrode possess electric conductivity.Pretreatment flexible dry electrode is wrapped up to the metallic film (as platinum, gold etc.) of one deck densification at polymer surfaces by the method for physical vapour deposition (PVD).
The present invention adopts the method for polymer casting, and the flexible dry electrode of making in conjunction with MEMS processing technology, not only has the array feeler structure of innovation, and have flexible feature.According to research, show, overhead position to the rear of the main region of EEG signals, the collection obstacle that but cause due to hair this position, all the time, adopting dry electrode technology to gather EEG signals is all electrode to be positioned over to forehead near the line of gaining fame and fortune, sentence the interference of avoiding hair.The present invention can insert feeler on the obstacle that overcomes hair in hair, and electrode is positioned over to the position that EEG signals is abundant, and the EEG signals of collection is more accurate, the comfortableness and the safety that also improve brain electrode simultaneously.
Accompanying drawing explanation
Fig. 1 (1)～Fig. 1 (3) is flexible dry electrode die schematic diagram of the present invention;
Fig. 2 is pretreatment flexible dry electrode moulding process schematic diagram of the present invention;
Fig. 3 is pretreatment flexible dry electrode pictorial diagram of the present invention;
Fig. 4 is the dry electrode pictorial diagram of the flexible brain electricity of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing, embodiments of the invention are elaborated: the present embodiment is implemented under take technical solution of the present invention as prerequisite, provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment.
As shown in Fig. 1 (1)～Fig. 1 (3), the present embodiment flexible dry electrode die comprises: upper bolster 1, and middle die holder 2, die shoe 3. wherein mold materials is aluminum.Upper bolster 1 is loop configuration, and interior radius of circle is 8mm, and exradius is 12mm.Upper bolster 1 is highly 5mm.Middle die holder 2 is the through hole of array shape.Die shoe 3 has the circular hole with middle die holder 2 identical array shapes and quantity, and the circular hole of die shoe 3 is blind hole.Upper bolster 1, middle die holder 2 and die shoe 3 use pins are fixed.
As shown in Figure 2, this figure is pretreatment flexible dry electrode 4 moulding process figure.First by polymer poly dimethyl siloxane according to certain proportioning stir, evacuation, then the polydimethylsiloxane of taking out vacuum is poured in flexible dry electrode die, flexible dry electrode die is put into baking oven, after within two hours under 70 ℃ of conditions, solidifying, take out, finally pretreatment flexible dry electrode is taken out in flexible dry electrode die.
As shown in Figure 3, obtained pretreatment flexible dry electrode is put into vacuum sputtering machine, just can form on pretreatment flexible dry electrode 4 surfaces the metallic film of one deck densification, obtain having the dry electrode 5 of flexible brain electricity of electric conductivity, as shown in Figure 4.
In the present embodiment, microneedle electrodes passes through MEMS technique: pretreatment flexible dry electrode is placed in sputtering chamber, be evacuated to about 2X10 in sputtering chamber
-6t, setting radio-frequency power is 150W, after 20～30 minutes, just can form metallic film at polymer surfaces.
The operation principle of the present embodiment is: EEG signals is that electroencephalogram is by brain electrode, the electrical activity that is present in cerebral tissue to be extracted on scalp by several hundred million neuronic movable generations in cerebral tissue, and EEG signals has reflected brain functional status at any time.The collection of normal conditions EEG signals is to adopt traditional wet electrode method, and wet electrode need to be through the processing of the auxiliary and skin of conductive paste when gathering, and this causes great inconvenience and discomfort to user.The dry electrode of flexible brain electricity is without the auxiliary of conductive paste and just can obtain EEG signals to the processing of skin, than the wet electrode of preoperative preparation of skin, this electrode is assisted eeg signal acquisition without conductive paste etc., greatly reduces the complexity gathering, and is beneficial to the long term monitoring collection of EEG signals.
In the present embodiment: when this application of installation is during in eeg signal acquisition, by head hoop or electrode cap, flexible dry electrode is fixed on to head upper, utilizes the feeler on electrode can be through hair contact hair.Because the present invention has flexibility function, can well follow the curved surface of human brain, increase the contact area of electrode and skin, reduce the contact impedance between electrode scalp and electrode.By the selection of the design to dry electrode structure and material, the not only collection to EEG signals for a long time, and avoid the interference of hair and outside noise.
As shown in table 1, the application request size used of the present embodiment:
Table 1
The present invention adds and designs structure cleverly in conjunction with existing MEMS technology for the dry electrode structure of flexible brain electricity of eeg signal acquisition, can be good at gathering EEG signals, compared with traditional wet electrode, do not need skin preparation process, can be for the detection of the long term brain signal of telecommunication.Its structure is small and exquisite, easy to use quick, can complete the high-quality record of microvolt level EEG signals.
Claims (8)
1. a preparation method for the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair, comprises that step is as follows:
1) utilize the method for machining to make flexible dry electrode die;
2) polymeric material is cast in flexible dry electrode die after by pretreatment, after baking oven heat treatment, form pretreatment flexible dry electrode;
3), at pretreatment flexible dry electrode surface sputter one deck conductive metal film, can obtain having the dry electrode of flexible brain electricity of electric conductivity;
Described flexible dry electrode die comprises upper bolster, middle die holder and die shoe;
The dry electrode of described flexible brain electricity comprises the feeler that is array stretching out on base and base, and its surface has one deck conductive metal film, and described feeler can insert hair, and the stratum germinativum that reaches skin carries out the collection of EEG signals.
2. the preparation method of the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair according to claim 1, is characterized in that, the described dry electrode employing of flexible brain electricity has biocompatible polymeric material polydimethylsiloxane and makes.
3. the preparation method of the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair according to claim 1, is characterized in that, the conductive metal film of the described dry electrode surface of flexible brain electricity is to obtain by MEMS PROCESS FOR TREATMENT.
4. the preparation method of the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair according to claim 1, it is characterized in that, described upper bolster in the form of a ring, annular inner circle is utilized boring cutter processing, interior circular diameter determines the size of the dry electrodes base of flexible brain electricity, highly determines the thickness of flexible dry electrodes base.
5. the preparation method of the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair according to claim 1, it is characterized in that, described middle die holder is the through hole of array shape, through hole utilizes drilling machine processing, the diameter in hole determines the size of the feeler of flexible dry electrode, highly determines the length of flexible dry electrode feeler.
6. the preparation method of the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair according to claim 1, is characterized in that, described die shoe has the circular hole with middle die holder identical array shape and quantity, and the circular hole of die shoe is blind hole.
7. the preparation method of the arrayed flexible electroencephalogramdry dry electrode of energy customer service obstacle of hair according to claim 1, it is characterized in that, described polymeric material pretreatment is to pump bubble after prepolymerized polydimethylsiloxane and firming agent mass ratio 10:1 are uniformly mixed.
According to claim 1 can customer service the preparation method of arrayed flexible electroencephalogramdry dry electrode of obstacle of hair, it is characterized in that, described baking oven heat treatment refers in baking oven 70 ° of C heat treatments 2 hours.
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Families Citing this family (11)
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| CN103932704A (en) * | 2013-01-23 | 2014-07-23 | 上海帝仪科技有限公司 | Skin contact device for wet electrode, wet electrode liquid storage box and brain wave collecting electrode with wet electrode liquid storage box |
| CN103767704B (en) * | 2014-01-20 | 2015-08-26 | 上海交通大学 | Dry electrode of a kind of standard for EEG measuring and preparation method thereof |
| CN103767703A (en) * | 2014-03-04 | 2014-05-07 | 上海海事大学 | Portable wireless electroencephalogram data real-time acquisition system and running method thereof |
| CN103876737B (en) * | 2014-04-08 | 2016-03-02 | 青岛柏恩鸿泰电子科技有限公司 | Based on dry type soft electrode and the preparation technology thereof of magnetically controlled DC sputtering technology |
| CN104510466B (en) * | 2014-12-15 | 2017-09-08 | 上海交通大学 | Dry electrode of flexible compound type and preparation method thereof |
| CN104799853A (en) * | 2015-04-09 | 2015-07-29 | 中国科学院半导体研究所 | Tough claw type dry electrode used for recording electroencephalogram and preparation method |
| CN108309291B (en) * | 2018-03-12 | 2023-11-24 | 复旦大学 | Flexible contact brain electrode and preparation method thereof |
| CN109124626B (en) * | 2018-07-26 | 2021-11-23 | 天津大学 | Novel passive flexible optical electrode |
| CN109875555B (en) * | 2019-03-05 | 2022-10-14 | 浙江中医药大学 | Non-invasive electroencephalogram recording electrode and manufacturing method thereof |
| CN110811611A (en) * | 2019-11-14 | 2020-02-21 | 深圳先进技术研究院 | Headband type biological signal acquisition device and preparation method thereof |
| CN112967832B (en) * | 2021-02-01 | 2023-02-28 | 天津理工大学 | Flexible comb-shaped semi-dry electrode and preparation method thereof |
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