The schizoid medicament of a kind of treatment
Technical field
The present invention relates to field of medicaments, specifically, relate to the schizoid medicament of a kind of treatment.
Background technology
Schizophrenia (schizophrenia) is a kind of psychiatric department disease, it is a kind of lasting, common chronic great mental sickness, be the most serious a kind of in the psychosis, be with basic individual character, the division of thinking, emotion, behavior, the inharmonious of ergasia and environment is the modal psychosis of a class of principal character, many between twenty and fifty morbidities, and then influence behavior and emotion.The main sign of schizophrenia is considered to basic thinking structure and cognitive chipping.This phenomenon of dissociating it is believed that and can cause the thinking form disorders and cause differentiating inherent and external experience.Suffer from schizoid people and may oneself represent that hallucination is arranged, perhaps, other people can find that their performance is influenced by hallucination.The patient also may express obvious vain hope conviction.
At present, the demand for the schizoid medicine of treatment increases day by day.
Summary of the invention
The purpose of this invention is to provide the schizoid medicament of a kind of treatment.
In order to realize purpose of the present invention, the invention provides the schizoid medicament of a kind of treatment, it is to be made by weight by following bulk drugs:
1~10 part of 1~5 part of Radix Platycodonis of 1~5 part of Pericarpium Citri Reticulatae of 1~10 part of Herba Lycopodii of Herba Eupatorii
1~10 part of 1~10 part of Rhizoma Acori Graminei of 1~5 part of Semen Armeniacae Amarum of 1~10 part of Caulis Hiptages benghalensis of Folium Perillae.
Preferably, it is to be made by weight by following bulk drugs:
5 parts of 4 parts of Radix Platycodoniss of 3 parts of Pericarpium Citri Reticulataes of 5 parts of Herba Lycopodiis of Herba Eupatorii
10 parts of 5 parts of Rhizoma Acori Graminei of 5 parts of Semen Armeniacae Amarums of 6 parts of Caulis Hiptages benghalensis of Folium Perillae.
Medicament of the present invention can be made various dosage forms with pharmaceutically acceptable carrier, such as tablet, capsule, soft capsule, pill, granule, oral liquid or decoction etc.Can adopt preparation technique means well known in the art to finish medicaments preparation of the present invention.
Described pharmaceutically acceptable carrier is well known, for being used to prepare the usual excipients or the adjuvant of above-mentioned preparation.Excipient or adjuvant commonly used comprise (but being not limited to) filler, lubricant, dispersant, wetting agent, binding agent, antioxidant or the like, for example, syrup, arabic gum, sorbitol, lactose, dextrin, starch, calcium carbonate, Pulvis Talci, Polyethylene Glycol, carboxymethyl starch sodium, magnesium stearate or the like.
The reasonable recipe of medicament of the present invention, curative effect is clear and definite, can treat schizophrenia effectively.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 capsule of the present invention
Take by weighing Herba Eupatorii 500 grams, Herba Lycopodii 300 grams, Pericarpium Citri Reticulatae 400 grams, Radix Platycodonis 500 grams, Folium Perillae 600 grams, Caulis Hiptages benghalensis 500 grams, Semen Armeniacae Amarum 500 grams, Rhizoma Acori Graminei 1000 grams.Be cut into coarse grain and add 12 times of amounts of water, 100 ℃ were heated 2 hours, filtered, and collected filtrate; Medicinal residues add 8 times of amounts of water, and 100 ℃ were heated 3 hours, filtered, and collected filtrate.Merge filtrate twice, filtrate decompression is concentrated into the thick paste of relative density about 1.25 (50 ℃), once finish spray drying, adorn 1000 capsules promptly.
Experimental example
Diagnostic criteria:
Draft according to " psychiatry " schizoid diagnostic criteria: verbal auditory ballucination appears in (1) repeatedly; (2) significantly loosening of association, splitting of thought, speech are discontinuous, or poverty of content of thought; (3) thought is inserted the people, is withdrawn, is sent out, thinking interrupts, or forced thinking; (4) passive, controlled, or known clearly experience; (5) vain hope of primary delusion (comprising delusional perception, delusional mood) or other absurdities; (6) thinking logic perversion, morbid symbolic thinking, or neologism; (7) parathymia, or significantly apathy; (8) tension syndrome, strange behavior, or unwise behavior; (9) tangible hypobulia or shortage.
Exclusion standard:
Get rid of organic mental disorders, and psychoactive drug substance and non-addiction material caused by mental disorder.The Split disease patient of not alleviating suffers from aforementioned two class diseases in this if break again as yet, should diagnose side by side.
Close case 60 examples of the standard of stating of selector, male's 30 examples wherein, 45 years old mean age, women's 30 examples, 51 years old mean age.
Therapeutic scheme
The capsule that makes among the oral embodiment 1, one day twice, each 3.Treating half a year continuously is a course of treatment.
Efficacy assessment standard
According to according to " psychiatry " (the Shen fishing. psychiatry is. Beijing: the People's Health Publisher, 2006:725-726) related standards, clinical efficacy drafted be produce effects: symptom fully or basic the disappearance, insight exists; Effectively: symptom disappears substantially, and the part insight exists; Invalid: symptom has no to alleviate, and insight does not recover.
Therapeutic outcome:
Through the treatment of a course of treatment, all the patient all meets the standard of produce effects.
Untoward reaction
After taking two groups of medicines, all do not find tangible untoward reaction.