Summary of the invention:
Technical problem to be solved by this invention is, a kind of turbid pus of expectorant of removing is provided, ascending the clear and descending the turbid, and expelling wind and cold, Xin Wen is sensible, regulates vim and vigour, a kind of Chinese medicine composition for the treatment of sinusitis of the stagnant blood stasis dispelling of row and preparation method thereof.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of sinusitis, wherein, each crude drug is formulated as follows according to unit of weight: Moschus 10-20g, Flos Magnoliae 20-30g, Radix Angelicae Dahuricae 10-20g, Rhizoma Chuanxiong 10-20g, Herba Delphinii Albocoerulei 10-20g, Herba Asari 5-10g, Radix Peucedani 10-20g, Fructus Arctii 10-20g, Radix Glycyrrhizae 15-25g, Radix Scrophulariae 10-20g, Rhizoma Belamcandae 10-20g, Cortex Mori 10-20g, Radix Platycodonis 10-20g, Radix Saposhnikoviae 15-25g.
Or each crude drug is formulated as follows according to unit of weight: Moschus 10-15g, Flos Magnoliae 20-25g, Radix Angelicae Dahuricae 10-15g, Rhizoma Chuanxiong 10-15g, Herba Delphinii Albocoerulei 10-15g, Herba Asari 5-8g, Radix Peucedani 10-15g, Fructus Arctii 10-15g, Radix Glycyrrhizae 15-20g, Radix Scrophulariae 10-15g, Rhizoma Belamcandae 10-15g, Cortex Mori 10-15g, Radix Platycodonis 10-15g, Radix Saposhnikoviae 15-20g.
Or each crude drug is formulated as follows according to unit of weight: Moschus 15-20g, Flos Magnoliae 25-30g, Radix Angelicae Dahuricae 15-20g, Rhizoma Chuanxiong 15-20g, Herba Delphinii Albocoerulei 15-20g, Herba Asari 6-10g, Radix Peucedani 15-20g, Fructus Arctii 15-20g, Radix Glycyrrhizae 20-25g, Radix Scrophulariae 15-20g, Rhizoma Belamcandae 15-20g, Cortex Mori 15-20g, Radix Platycodonis 15-20g, Radix Saposhnikoviae 20-25g.
Or each crude drug is formulated as follows according to unit of weight: Moschus 12-18g, Flos Magnoliae 22-28g, Radix Angelicae Dahuricae 12-18g, Rhizoma Chuanxiong 12-18g, Herba Delphinii Albocoerulei 12-18g, Herba Asari 7-9g, Radix Peucedani 12-18g, Fructus Arctii 12-18g, Radix Glycyrrhizae 18-22g, Radix Scrophulariae 12-18g, Rhizoma Belamcandae 12-18g, Cortex Mori 12-18g, Radix Platycodonis 12-18g, Radix Saposhnikoviae 18-22g.
Object to better implement the present invention, the present invention also provides a kind of preparation method of the Chinese medicine composition for the treatment of sinusitis, and wherein, in the time that described Chinese medicine composition is honey refining pill, its preparation method is as follows:
Each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters filtrate for later use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters filtrate for later use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, cooling after drying, and mixes and is twisted into slice, pill wax seal packing with Mel;
Or when the dosage form of Chinese medicine composition is capsule, its preparation method is as follows:
Each crude drug is added to the ethanol of 10 times of amounts of gross weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is 20 ℃ 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
The present invention removes the turbid pus of expectorant, ascending the clear and descending the turbid, and expelling wind and cold, Xin Wen is sensible, regulate vim and vigour, the stagnant blood stasis dispelling of row, medicine source is extensive, and human body is had no side effect, treatment sinusitis effect is remarkable, and according to clinical case 120 number of cases, according to comparing, effective percentage reaches 83.1%, is well 92.4%.
The specific embodiment:
The present invention removes the turbid pus of expectorant, ascending the clear and descending the turbid, and expelling wind and cold, Xin Wen is sensible, regulates vim and vigour, the stagnant blood stasis dispelling of row, medicine source is extensive, and human body is had no side effect, and treatment sinusitis effect is remarkable.
In the present invention, each crude drug is as follows:
Moschus, pungent, temperature, GUIXIN, spleen channel.Be used for the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving.Wang Haogu: treat nose chamber anosmia.
Flos Magnoliae, pungent, temperature.Attach to the lung and stomach meridians.Cold-dispelling, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.Cure mainly: dispel the wind, sensible.Control headache, nasal sinusitis, has a stuffy nose obstructed, toothache." not Lu ": " stuffy nose relieving plug, tears go out for warming middle-JIAO expelling pathogenic factors from muscles, sharp nine orifices, control swelling of the face and draw toothache, dizziness, body several as on car and boat person.Raw beard and hair, removes tapeworm.
The Radix Angelicae Dahuricae, warm in nature, acrid in the mouth.Enter lung, spleen, stomach warp.The cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache." detailed outline ": control nasal sinusitis, epistaxis, toothache, supraorbital bone pain, large intestine constipation due to pathogenic wind, bleeding urine, married woman's blood dizziness due to wind pathogen fortune, regurgitation of food from the stomach is told food; Solution arsenic poison, snakebite, cutter arrow incised wound.
Rhizoma Chuanxiong, acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Herba Delphinii Albocoerulei, hardship, cold.Enter stomach, large intestine two warps.For heat-clearing and toxic substances removing, damp eliminating heat extraction.
Herba Asari, " herbal classic ": " acrid in the mouth, temperature." " Thunder God is concocted property of medicine solution ": " enters the heart, liver, gallbladder, board four warps." dispel the wind, cold expelling, row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Should lead to lung key: for rhinitis, sinusitis.
Radix Peucedani, cold nature, bitter in the mouth, pungent.Return lung; Spleen; Liver Channel.Cure mainly: affection due to external wind and heat; Lung-heat phlegm stagnancy; Cough with asthma abundant expectoration; Expectorant Huang is sticky; Contrary lack of appetite; Chest and diaphragm is full vexed." detailed outline ": clearing away lung-heat, the heat of reducing phlegm, loose ailment said due to cold or exposure.
Fructus Arctii, acrid in the mouth; Bitter; Cold in nature.Return lung; Stomach warp.Cure mainly: anemopyretic cold, epidemic febrile disease from the beginning of; Wind heat or cough due to lung-heat, cough up phlegm not smooth; Laryngopharynx swelling and pain; Macule is not saturating; At the measles initial stage, rash goes out not smooth and rubella pruritus; Sore swollen toxin and mumps etc.Raw with can loosening bowel to relieve constipation, pyretic toxicity red swelling and pain of throat." Bencao Jingshu ": disliking in fact, is the key medicine of loose wind except thermal detoxification.Pungent can eliminating stagnation, hardship can expel the heat-evil, the loose visceral-qi of accumulation of heat Clear and Bright, therefore improving eyesight and invigorating middle warmer.The institute of wind hinders, defend gas and must stop up, stop up heating, Xin Liang dismiss show gas and, wind without stay.Hide the swollen all flaccidity of device main air poison; The main lung moistening of element, eliminating stagnation gas, sore-throat relieving diaphragm, peeling skin wind, logical twelve channels and collaterals person, know this meaning ear.
Radix Glycyrrhizae, Radix Glycyrrhizae property is flat, and sweet in the mouth, returns 12 warps.Have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic be so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, emergency removing toxic substances, mediation hundred medicines." medicine justice ": Radix Glycyrrhizae, raw with cool and pathogenic fire purging, main loose pathogenic factor in the exterior, subduing inflammation, sore-throat relieving pain, separates hundred poison of drug, except stomach accumulated heat, goes urinary catheter bitterly, and the power of this sweet cool heat extraction is also.
Radix Scrophulariae, bitter in the mouth is salty.Cold nature.Nontoxic.For removing heat from blood YIN nourishing, eliminating fire and detoxication, fever excessive thirst, spontaneous sweating, constipation, haematemesis nose bleeding, pharyngolaryngitis, pulmonary tuberculosis.
Rhizoma Belamcandae, hardship, cold.Enter lung, Liver Channel.Heat-clearing and toxic substances removing, throat, expectorant saliva.Be used for experiencing wind heat, or expectorant heat is stopped up the diseases such as the laryngopharynx swelling and pain due to containing.Rhizoma Belamcandae is to control the medicine that laryngopharynx swelling and pain is conventional, can heat clearing away poison, detumescence pain, the fit applications such as normal and Fructus Arctii, Radix Platycodonis, Radix Glycyrrhizae.
Cortex Mori, sweet cold, enter lung meridian.For eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For lung-heat cough with asthma, the edema of the face, the diseases such as dysuria.Shennong's Herbal: sweet in the mouth, cold.Cure mainly damaging the spleen and stomach, five kinds of over strain, six types of severe debility disease, weakness and emaciation, metrorrhagia, pulse disappeared, tonify deficiency, QI invigorating.Leaf: main except cold and heat, perspire.
Radix Platycodonis, bitter in the mouth, pungent, slightly warm in nature.Enter lung meridian.Energy expelling phlegm for arresting cough, and have lung qi dispersing, evacuation of pus effect.Effect: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.
Radix Saposhnikoviae, acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.Cure mainly: diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Prescription of the present invention is: each crude drug is formulated as follows according to unit of weight:
Moschus 10-20g, Flos Magnoliae 20-30g, Radix Angelicae Dahuricae 10-20g, Rhizoma Chuanxiong 10-20g, Herba Delphinii Albocoerulei 10-20g, Herba Asari 5-10g, Radix Peucedani 10-20g, Fructus Arctii 10-20g, Radix Glycyrrhizae 15-25g, Radix Scrophulariae 10-20g, Rhizoma Belamcandae 10-20g, Cortex Mori 10-20g, Radix Platycodonis 10-20g, Radix Saposhnikoviae 15-25g.
Or each crude drug is formulated as follows according to unit of weight: Moschus 10-15g, Flos Magnoliae 20-25g, Radix Angelicae Dahuricae 10-15g, Rhizoma Chuanxiong 10-15g, Herba Delphinii Albocoerulei 10-15g, Herba Asari 5-8g, Radix Peucedani 10-15g, Fructus Arctii 10-15g, Radix Glycyrrhizae 15-20g, Radix Scrophulariae 10-15g, Rhizoma Belamcandae 10-15g, Cortex Mori 10-15g, Radix Platycodonis 10-15g, Radix Saposhnikoviae 15-20g.
Or each crude drug is formulated as follows according to unit of weight: Moschus 15-20g, Flos Magnoliae 25-30g, Radix Angelicae Dahuricae 15-20g, Rhizoma Chuanxiong 15-20g, Herba Delphinii Albocoerulei 15-20g, Herba Asari 6-10g, Radix Peucedani 15-20g, Fructus Arctii 15-20g, Radix Glycyrrhizae 20-25g, Radix Scrophulariae 15-20g, Rhizoma Belamcandae 15-20g, Cortex Mori 15-20g, Radix Platycodonis 15-20g, Radix Saposhnikoviae 20-25g.
Or each crude drug is formulated as follows according to unit of weight: Moschus 12-18g, Flos Magnoliae 22-28g, Radix Angelicae Dahuricae 12-18g, Rhizoma Chuanxiong 12-18g, Herba Delphinii Albocoerulei 12-18g, Herba Asari 7-9g, Radix Peucedani 12-18g, Fructus Arctii 12-18g, Radix Glycyrrhizae 18-22g, Radix Scrophulariae 12-18g, Rhizoma Belamcandae 12-18g, Cortex Mori 12-18g, Radix Platycodonis 12-18g, Radix Saposhnikoviae 18-22g.
Chinese medicine composition of the present invention is prepared as honey refining pill or capsule:
In the time that Chinese medicine composition is honey refining pill, its preparation method is as follows: each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters filtrate for later use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters filtrate for later use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, cooling after drying, and mixes and is twisted into slice, pill wax seal packing with Mel;
Or when the dosage form of Chinese medicine composition is capsule, its preparation method is as follows:
Each crude drug is added to the ethanol of 10 times of amounts of gross weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is 20 ℃ 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
Concrete example is as follows:
Embodiment 1
Zhang, 27 years old, man, pus tears are many: nasal mucus mostly is purulence or sticky purulence, yellow or yellow green, how much indefinite measure, and multithread is to bottleneck throat, one-sided frowziness.Nasal obstruction, rhinorrhea, hyposmia, hypopnea, companion's feeling of fullness in the head, eyebrow rib is done acid, dry pharynx pain, sticky the coughing up of expectorant told, red tongue, yellow and greasy fur, slippery and rapid pulse.Its expectorant deep love lung, should eliminating phlegm and clearing away heat, and lung qi dispersing is sensible.Take following prescription: Moschus 20g, Flos Magnoliae 30g, Radix Angelicae Dahuricae 20g, Rhizoma Chuanxiong 20g, Herba Delphinii Albocoerulei 20g, Herba Asari 10g, Radix Peucedani 20g, Fructus Arctii 20g, Radix Glycyrrhizae 25g, Radix Scrophulariae 20g, Rhizoma Belamcandae 20g, Cortex Mori 20g, Radix Platycodonis 20g, Radix Saposhnikoviae 25g.Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 20 doses, and nasal obstruction symptom obviously alleviates, and continues to take 15 doses, giddy, and headache transference cure, smooth breathing, continues to take 10 doses of drug withdrawals, cures.After half a year, visit, not recurrence.
Embodiment 2
Mrs Huang, 36 years old, heavy when light when nasal obstruction, nasal mucus was rare clearly, met cold increasing the weight of, hyposmia, headache, dizziness.Inspection is shown in that intranasal swelling color is light.Pale tongue, Tai Bai or thick, relaxed and soft pulse.On its lung-heat, steam, nose key Yong Sai, should heat-clearing and fire-dispersing, and lung qi dispersing is sensible.Use following prescription: Moschus 10g, Flos Magnoliae 20g, Radix Angelicae Dahuricae 10g, Rhizoma Chuanxiong 10g, Herba Delphinii Albocoerulei 10g, Herba Asari 5g, Radix Peucedani 10g, Fructus Arctii 10g, Radix Glycyrrhizae 15g, Radix Scrophulariae 10g, Rhizoma Belamcandae 10g, Cortex Mori 10g, Radix Platycodonis 10g, Radix Saposhnikoviae 15g.Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 20 doses, and nasal obstruction symptom obviously alleviates, and continues to take 12 doses, giddy, and headache transference cure, smooth breathing, continues to take 10 doses of drug withdrawals, cures.After three months, visit, not recurrence.
Embodiment 3
Section certain, man.35 years old, the nasal obstruction time was long, and nasal mucus is many, glued Huang or sticky white, and baryo,dmia, has a stuffy nose, and rhinorrhea is had a headache and often had regularly, or the cheek that coexists, or the forehead that coexists, and often also bitterly, olfactory sensation is poor for top, top and temple simultaneously, and gas leads to known taste, light red tongue, white and thin fur, deep-slow pulse.Should dispel cold by warming the interior, clear the nasal passage, the stagnant blood stasis dispelling of row.Take following prescription: Moschus 15g, Flos Magnoliae 25g, Radix Angelicae Dahuricae 15g, Rhizoma Chuanxiong 15g, Herba Delphinii Albocoerulei 15g, Herba Asari 8g, Radix Peucedani 15g, Fructus Arctii 15g, Radix Glycyrrhizae 20g, Radix Scrophulariae 15g, Rhizoma Belamcandae 15g, Cortex Mori 15g, Radix Platycodonis 15g, Radix Saposhnikoviae 20g.Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 16 doses, and nasal obstruction symptom obviously alleviates, and continues to take 12 doses, giddy, and headache transference cure, smooth breathing, continues to take 12 doses of drug withdrawals, cures.After three months, visit, not recurrence.
Embodiment 4, Mr. Ma, 29 years old, nasal obstruction, rhinorrhea, hypopnea, outside hyposmia, and by dry pharynx pain, the sticky difficulty of expectorant is coughed up, rolling pulse, red tongue etc., dialectical is expectorant deep love lung, should eliminating phlegm and clearing away heat, lung qi dispersing is sensible, adjusting vim and vigour.Take following prescription: Moschus 18g, Flos Magnoliae 28g, Radix Angelicae Dahuricae 18g, Rhizoma Chuanxiong 18g, Herba Delphinii Albocoerulei 18g, Herba Asari 9g, Radix Peucedani 18g, Fructus Arctii 18g, Radix Glycyrrhizae 22g, Radix Scrophulariae 18g, Rhizoma Belamcandae 18g, Cortex Mori 18g, Radix Platycodonis 18g, Radix Saposhnikoviae 22g.Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 16 doses, and nasal obstruction symptom obviously alleviates, and continues to take 12 doses, giddy, and headache transference cure, smooth breathing, continues to take 12 doses of drug withdrawals, cures.After three months, visit, not recurrence.
Expelling wind and cold of the present invention, Xin Wen is sensible, regulates vim and vigour, the stagnant blood stasis dispelling of row, warming the lung and benefiting QI, expelling pathogenic wind and restoring the functions of orifices in face, and medicine source is extensive, and harmless, treatment chronic rhinitis effect is remarkable.According to clinical case 120 number of cases, according to comparing, effective percentage reaches 83.1%, is well 92.4%.