CN102524891A - Dangshen health-care beverage and preparation method thereof - Google Patents

Abstract

The invention discloses a Codonopsis health drink. The formula is that every 1000ml of the Codonopsis health drink contains: 20-100g of fresh Codonopsis or 5-30g of Codonopsis medicinal materials, 20-100g of fresh hawthorn fruit or 5-30g of dried hawthorn fruit, 5-15g of sweet-scented osmanthus, and 0g of fresh wolfberry fruit. -100g or dried wolfberry fruit 0-25g, inositol 100-800mg, taurine 0.1-0.8g, citric acid 0-20g, sucrose 0-25g, honey 0-30g, the balance is purified water. The beneficial effects of the present invention are as follows: 1) The extraction is carried out by microwave combined with water boiling, and the microwave extraction time and material-liquid ratio are optimized, the extraction efficiency and production speed are greatly improved, and the processing process reduces the impact on the product. The destruction of nutritional components greatly retains the nutritional and functional components of raw materials; 2) Using fresh raw materials to process and prepare beverages prolongs the shelf life of raw materials. This method can realize industrial production and improve the resource utilization of Codonopsis pilosula; 3) Preparation The process is simple, the production cost is low, the prepared health beverage has good taste, and long-term drinking has strong nutrition and health effects. Mainly manifested as invigorating qi, nourishing blood, lowering blood pressure, lowering blood fat, relieving fatigue, refreshing and beautifying and other effects.

Description

Codonopsis health beverage and preparation method thereof

technical field

The invention relates to a preparation method of a functional health drink, in particular to a Codonopsis health drink and a preparation method thereof.

Background technique

With the continuous improvement of people's living standards and consumer demand, the functionalization and diversification of beverage products has become the general trend. The percentage of China's functional drinks in the soft drink market has risen to about 20% in 2008. The huge market potential has led many companies to rush to play the "functional" brand in recent years. After Red Bull, the domestic functional beverage market can be described as a constant stream of new products, not only the involvement of beverage giants, but also the involvement of non-industry capital. However, it seems that compared with the mineral water, fruit juice and other beverage markets, the overall domestic functional beverage market is not large, and its development is relatively lagging behind. The annual consumption of functional beverages per capita in the world has reached 7 kg, while that in my country is only 0.5 kg. It can be seen that there is still considerable room for market growth in functional drinks.

Also do not have the health beverage with multiple health care functions and auxiliary therapeutic effect prepared with codonopsis hawthorn as the main raw material on the market at present.

Codonopsis pilosula, sweet in taste; flat in nature, belongs to the spleen and lung meridians, and is used to treat weakness of the spleen and stomach, lack of food and loose stools, weakness of limbs, dyspnea and cough due to lung deficiency, shortness of breath and spontaneous sweating, thirst, and slight deficiency of both qi. Its main function is to invigorate qi and nourish blood at the same time, which is a major feature of it. Codonopsis pilosula has an excitatory effect on the nervous system and can enhance the body's resistance; it can increase red blood cells and hemoglobin in rabbits; it can expand peripheral blood vessels and lower blood pressure, and can inhibit the boosting effect of adrenaline; it has the functions of regulating gastrointestinal motility, anti-ulcer, Inhibit the secretion of gastric acid, reduce the activity of pepsin, etc.; it can also improve the leukopenia caused by chemotherapy and radiation.

Hawthorn, every 100 grams of fresh hawthorn pulp contains: vitamin C 89 mg, ranking third in fruits after fresh jujubes and kiwis; vitamin B2 content is 5 times higher than apples, comparable to bananas, and ranks first among fruits; 0.82 grams of carotene, 10 times that of apples; 85 mg of calcium, second only to olives among the fruits. The content of vitamin E in fresh hawthorn fruit is also the crown of fruit. It is also rich in protein, amino acid and minerals such as sodium, potassium and manganese. In addition, the pectin content in hawthorn ranks first among all fruits. Pectin has the effect of lowering cholesterol and blood sugar and preventing gallstones. According to the latest research, pectin also has the effect of radiation protection, which can take away half of the radioactive elements-strontium, cobalt, palladium, etc. from the body. A large amount of dietary fiber in hawthorn can be regarded as a "scavenger" in the intestines. Hawthorn not only has high nutritional value, but also has high medicinal value. Because hawthorn contains a variety of active substances, such as triterpenoids, organic acids, dietary fiber, flavonoids, and vitexin, it can dilate blood vessels, increase coronary blood flow, improve heart function, soften blood vessels, lower blood pressure, help Digestion, increase appetite, eliminate accumulated food, anti-cancer and anti-cancer effects. Hawthorn also has bactericidal and astringent effects, so doctors also use hawthorn to treat diseases such as bacillary dysentery and enteritis. Drinking hawthorn tea every day, it will take a long time to achieve the effect of lowering blood fat and softening blood vessels.

Lycium barbarum is sweet and flat in nature, and belongs to the liver and kidney meridians. It can nourish the kidney and essence, nourish the liver and improve eyesight, nourish blood and calm the nerves, promote body fluid and quench thirst, moisten the lungs and relieve cough. Control liver and kidney yin deficiency, soreness of the waist and knees, dizziness, dizziness, blurred vision and tears, consumptive cough, thirst, nocturnal emission. Contains carotene, betaine, vitamin A, vitamin B1, vitamin B2, vitamin C, calcium, phosphorus, iron, etc. It has the pharmacological effects of increasing white blood cell activity and promoting liver cell regeneration, and can also lower blood pressure, blood sugar, and blood lipids. The content of vitamin C in wolfberry is higher than that of orange, the content of β-carotene is higher than that of carrot, and the content of iron is higher than that of steak. Lycium barbarum also has the function of aphrodisiac. Lycium barbarum, as a good tonic for both medicine and food, can be taken all year round, which can improve physical fitness and help sleep. For women, eating wolfberry often can also play a role in whitening and beautifying.

Osmanthus fragrans is warm in nature and pungent in taste. It can relieve tension, drink it regularly, it can purify the body and mind, balance the nervous system, and achieve a refreshing effect. In addition, it also has the effects of anti-cancer, clearing heat and detoxification, expelling wind and cold, moistening spleen and stomach, increasing appetite and losing weight. It is effective for waking up the stomach, promoting body fluid and relieving cough, reducing phlegm, analgesic, and smoothing Qi. It can strengthen the stomach and intestines, relieve duodenal ulcer, gastroptosis, flatulence and other gastrointestinal diseases. It can also treat dry mouth and flatulence, so as to nourish the body and moisten the lungs, and eliminate gastrointestinal discomfort; it can also treat frightened children, stomach pain, toothache, bad breath and other symptoms. Drinking osmanthus tea often can whiten the skin, remove toxins from the body and relieve constipation.

Contents of the invention

The object of the present invention is exactly to aim at the defect in the above-mentioned prior art, and provides a kind of health beverage with multiple health care functions and auxiliary therapeutic effects prepared with codonopsis pilosula and hawthorn as main raw materials, supplemented with wolfberry and osmanthus fragrans.

In order to achieve the above object, the technical solution provided by the invention is:

Codonopsis health drink, the formula is that every 1000ml of Codonopsis health drink contains:

20-100g fresh Codonopsis or 5-30g Codonopsis herb, 20-100g fresh hawthorn fruit or 5-30g dried hawthorn fruit, 5-15g sweet-scented osmanthus, 0-100g wolfberry fresh fruit or 0-25g wolfberry dried fruit, inositol 100-800mg, taurine 0.1-0.8g, citric acid 0-20g, sucrose 0-25g, honey 0-30g, the balance is pure water.

The above formula can also contain:

Fresh Codonopsis 50-100g, Hawthorn fresh fruit 50-100g, Osmanthus fragrans 5g, Lycium barbarum fresh fruit 5-25g, Inositol 300-600mg, Taurine 0.2-0.6g, Citric acid 5-10g, Sucrose 10-20g, Honey 10-25g , and the balance is pure water.

The above formula can also contain:

Codonopsis 20-30g, hawthorn dried fruit 20-50g, osmanthus 5-10g, wolfberry dried fruit 0-25g, inositol 400-600mg, taurine 0.5-0.6g, citric acid 8-10g, sucrose 15-20g, honey 15g -25g, the balance is purified water.

Another object of the present invention is to provide the preparation method of above-mentioned Codonopsis Codonopsis health drink, comprising the following steps:

1) Weighing fresh Codonopsis pilosula, dried hawthorn and dried wolfberry according to the recipe, steaming at 90-130°C for 5-30 minutes, and then adding sweet-scented osmanthus in the prescribed amount to obtain mixed raw materials; or

The medicinal material Codonopsis pilosula, fresh hawthorn fruit and fresh wolfberry fruit are directly mixed with sweet-scented osmanthus in the formula to obtain mixed raw materials;

2) Add pure water equivalent to 1-3 times the mass of the mixed raw material to the mixed raw material obtained in step 1), and carry out microwave extraction. The extraction condition is a 200-800W microwave oven microwave extraction for 5-15 minutes to obtain a preliminary treatment mixed material ;

3) Put the preliminary treatment mixture obtained in step 2) into a cooking tank for cooking, and add pure water to 5-10 times the mass of the mixed raw material, decoct for 40-120 minutes and filter through an 80-100 mesh sieve to obtain Filtrate one and material residue;

4) Put the slag obtained in step 3) into a cooking tank, add pure water equivalent to 5-8 times of the mixed raw materials, decoct for 30-60 minutes, filter to obtain filtrate 2, and the filter mesh number is 80-100 mesh;

5) mixing the filtrate 1 obtained in step 3) with the filtrate 2 obtained in step 4) to obtain the total extract;

6) Weigh taurine and inositol according to the formula, add a small amount of pure water to dissolve and add to the total extract obtained in step 5), stir evenly, then add the formula amount of sucrose, citric acid and honey, and then filter , 80-100 mesh; then the filtrate is fixed to 1000ml with purified water to obtain the secondary treatment mixture;

7) After the secondary treatment mixture obtained in step 6) is subjected to high-pressure homogenization treatment for 1-2 times at a pressure of 40-50MPa and a temperature of 40-80°C, it is placed in an ultrasonic instrument with a power of 100-1500W and a frequency of 40-100KHz Perform ultrasonic degassing for 30-120 seconds, high-temperature sterilization for 5-20 seconds, and the sterilization temperature is 138-150°C to obtain a semi-finished health beverage;

8) Filling, inspecting and packaging the semi-finished health drink obtained in step 7) to obtain the finished product of Codonopsis health drink.

The preparation method of the above-mentioned Codonopsis health drink includes the following steps:

1) Wash the fresh hawthorn fruit and slice it, with a thickness of 1-5 mm, wash the medicinal material of Codonopsis pilosula and cut it into sections with a length of 1-3 cm, mix the medicinal material of Codonopsis pilosula, fresh hawthorn fruit and sweet-scented osmanthus in the prescribed amount to obtain a mixed raw material;

2) Adding purified water equivalent to 2 times the total weight of raw materials, and performing microwave extraction, the extraction condition is 500W microwave oven microwave extraction for 10 minutes, to obtain the preliminary treatment mixture;

3) Put the preliminary treatment mixture obtained in step 2) into a cooking tank for cooking, and add purified water to 5 times the mass of the mixed raw material, decoct for 60 minutes and filter through an 80-100 mesh sieve to obtain the filtrate and material slag;

4) Put the slag obtained in step 3) into a cooking tank, add pure water equivalent to 5 times of the mixed raw materials, decoct for 40 minutes, filter to obtain filtrate 2, and the filter mesh number is 80-100 mesh;

5) mixing the filtrate 1 obtained in step 3) with the filtrate 2 obtained in step 4) to obtain the total extract;

6) Weigh taurine and inositol according to the formula, add a small amount of pure water to dissolve and add to the total extract obtained in step 5), stir evenly, then add the formula amount of sucrose, citric acid and honey, and then filter , the filter mesh number is 80-100 mesh, and then the filtrate is fixed to 1000ml with purified water to obtain the secondary treatment mixture;

7) After the secondary treatment mixture obtained in step 6) is subjected to high-pressure homogenization treatment twice at a pressure of 45 MPa and a temperature of 80° C., ultrasonic degassing is performed for 60 seconds in an ultrasonic instrument with a power of 100 W and a frequency of 40 KHz, and then high-temperature sterilization 5s, the sterilization temperature is 140-150°C, and the semi-finished health drink is obtained;

8) Filling, inspecting and packaging the semi-finished health drink obtained in step 7) to obtain the finished product of Codonopsis health drink.

The preparation method of the above-mentioned Codonopsis health drink includes the following steps:

1) Weighing fresh Codonopsis pilosula, dried hawthorn and dried wolfberry according to the recipe, and steaming at 100°C for 25 minutes, then adding sweet-scented osmanthus in the prescribed amount to obtain mixed raw materials; or

The medicinal material Codonopsis pilosula, fresh hawthorn fruit and fresh wolfberry fruit are directly mixed with sweet-scented osmanthus in the formula to obtain mixed raw materials;

2) Adding purified water equivalent to 2 times the total weight of raw materials, and performing microwave extraction, the extraction condition is 500W microwave oven microwave extraction for 5-15 minutes, to obtain the preliminary treatment mixture;

3) Put the preliminary treatment mixture obtained in step 2) into a cooking tank for cooking, and add pure water to 5-8 times the mass of the mixed raw material, decoct for 40-120 minutes and filter through an 80-100 mesh sieve to obtain Filtrate one and material residue;

4) Put the slag obtained in step 3) into a cooking tank, add pure water equivalent to 5-6 times of the mixed raw materials, decoct for 30-60 minutes, filter to obtain filtrate 2, and the filter mesh number is 80-100 mesh;

5) mixing the filtrate 1 obtained in step 3) with the filtrate 2 obtained in step 4) to obtain the total extract;

6) Weigh taurine and inositol according to the formula, add a small amount of pure water to dissolve and add to the total extract obtained in step 5), stir evenly, then add the formula amount of sucrose, citric acid and honey, and then filter , the filter mesh number is 80-100 mesh, and then the filtrate is fixed to 1000ml with purified water to obtain the secondary treatment mixture;

7) After the secondary treatment mixture obtained in step 6) is subjected to high-pressure homogenization treatment twice at a pressure of 40-50 MPa and a temperature of 65° C., ultrasonic degassing is carried out in an ultrasonic instrument with a power of 500 W and a frequency of 60 KHz for 60 seconds. Sterilize for 20-30 minutes at a temperature of 121°C to obtain a semi-finished health drink;

8) Filling, inspecting and packaging the semi-finished health drink obtained in step 7) to obtain the finished product of Codonopsis health drink.

The preparation method of the above-mentioned Codonopsis health drink includes the following steps:

1) Weighing fresh Codonopsis pilosula, dried hawthorn and dried wolfberry according to the recipe, and steaming at 92°C for 25 minutes, then adding sweet-scented osmanthus in the prescribed amount to obtain mixed raw materials; or

The medicinal material Codonopsis pilosula, fresh hawthorn fruit and fresh wolfberry fruit are directly mixed with sweet-scented osmanthus in the formula to obtain mixed raw materials;

2) adding pure water equivalent to 3 times the total weight of raw materials, and performing microwave extraction, the extraction condition is 600-800W microwave oven microwave extraction for 8 minutes, to obtain the preliminary treatment mixture;

3) Put the preliminary treatment mixture obtained in step 2) into a cooking tank for cooking, and add pure water to 8 times the mass of the mixed raw material, decoct for 120 minutes and then filter through an 80-100 mesh sieve to obtain the filtrate one and the material slag;

4) Put the slag obtained in step 3) into a cooking tank, add pure water equivalent to 6 times the amount of mixed raw materials, decoct for 60 minutes, and filter to obtain filtrate 2, the filter mesh number is 80-100 mesh sieve;

5) mixing the filtrate 1 obtained in step 3) with the filtrate 2 obtained in step 4) to obtain the total extract;

6) Weigh taurine and inositol according to the formula, add a small amount of pure water to dissolve and add to the total extract obtained in step 5), stir evenly, then add the formula amount of sucrose, citric acid and honey, and then filter , the filter mesh number is 80-100 mesh sieve; then the filtrate is fixed to 1000ml with purified water to obtain the secondary treatment mixture;

7) After the secondary treatment mixture obtained in step 6) is subjected to high-pressure homogenization treatment twice at a pressure of 40-50 MPa and a temperature of 55° C., ultrasonic degassing is carried out in an ultrasonic instrument with a power of 1000 W and a frequency of 60 KHz for 45 seconds. Sterilize for 10s at a temperature of 140°C to obtain a semi-finished health beverage;

8) Filling, inspecting and packaging the semi-finished health drink obtained in step 7) to obtain the finished product of Codonopsis health drink. .

The beneficial effects of the present invention are:

The present invention combines traditional Chinese medicine theory and modern scientific theory, and is prepared from Codonopsis pilosula and hawthorn as main raw materials. Compared with the prior art, the present invention has the following advantages:

1) The present invention adopts the process of microwave combined with water boiling for extraction, and optimizes the time and solid-liquid ratio of microwave extraction, the extraction efficiency and production speed are greatly improved, and the damage to the nutritional components contained in the product is reduced during the processing process, Greatly retain the nutritional and functional ingredients of raw materials.

2) Another advantage of the present invention is that fresh raw materials can be used to process and prepare beverages, which prolongs the shelf life of raw materials. This method can realize industrial production and improve the resource utilization rate of Codonopsis pilosula.

3) The preparation process of the present invention is simple, the production cost is low, and the prepared health drink tastes good, and long-term drinking has a strong nutritional and health effect. Mainly manifested as invigorating qi, nourishing blood, lowering blood pressure, lowering blood fat, relieving fatigue, refreshing and beautifying and other effects.

Detailed ways

Example 1:

The prescription of present embodiment Codonopsis health beverage is that every 1000ml beverage contains:

50g of fresh Codonopsis, 50g of hawthorn, 5g of osmanthus, 25g of wolfberry, 400mg of inositol, 0.3g of taurine, 10g of citric acid, 10g of sucrose, 15g of honey, and the rest is pure water.

The present embodiment Codonopsis pilosula health drink production technology is as follows:

Wash the ripe hawthorn fresh fruit, cut into 1-5mm thin slices for later use, wash the fresh Codonopsis pilosula, and cut into 1-3cm small pieces for later use. According to the formula, we weigh the cleaned Codonopsis fresh medicinal materials, hawthorn fresh fruit, and sweet-scented osmanthus, add 2 times the amount of pure water equivalent to the total raw materials, microwave 500W ultrasonic extraction for 10 minutes, and then put them in a cooking tank, and add pure water to the equivalent of 5 times the raw materials. Double the amount, decoct for 60 minutes, filter to obtain the filtrate. The medicinal dregs were added with purified water equivalent to 5 times the amount of the raw material, decocted for 40 minutes, filtered to obtain a filtrate, and the two filtrates were combined to obtain a total extract.

Weigh taurine (Wuhan Yuancheng Science and Technology Development Co., Ltd., 694195) and inositol (Hebei Yuwei Food Preparation Co., Ltd., 102713531116) according to the formula, dissolve with a small amount of pure water, add to the above total extract, and stir well , then weigh the sucrose, citric acid, and honey of the formula and add them to the extract to adjust the flavor. After adjusting to the best flavor, filter and dilute the filtrate to 1000ml with purified water. The filtrate after constant volume was subjected to high-pressure homogenization treatment twice at a pressure of 45MPa and a temperature of 80°C, then ultrasonically degassed in a 100W, 40KHz ultrasonic instrument for 1min, and then sterilized at high temperature for 5s at a temperature of 140-150°C. Filling, inspection, and packaging are finished products.

Example 2:

The prescription of present embodiment Codonopsis health beverage is that every 1000ml beverage contains:

50g fresh Codonopsis pilosula or 20g Codonopsis pilosula, 50g fresh hawthorn fruit or 20g dried hawthorn fruit, 5-15g sweet-scented osmanthus, 25g fresh wolfberry fruit or 10g dried wolfberry fruit, 500mg inositol, 0.5g taurine, 8g citric acid, 15g sucrose, 20g honey, The amount is purified water. Weigh Codonopsis pilosula, hawthorn, and wolfberry according to the formula, wash them, and steam them at 100°C for 25 minutes. If they are fresh medicinal materials of Codonopsis pilosula, fresh hawthorn fruit, and fresh wolfberry fruit, steam treatment is not required. Add 2 times the amount of pure water to the total raw material, extract with 500W microwave for 5-15 minutes, then put it in a cooking tank, add pure water to 5-8 times the amount of raw material, decoct for 40-120 minutes, filter to obtain the filtrate. The dregs are added with purified water equivalent to 5-6 times the amount of raw materials, decocted for 30-60 minutes, filtered to obtain a filtrate, and the two filtrates are combined to obtain a total extract.

Weigh taurine and inositol according to the formula, dissolve them with a small amount of pure water, add them to the above-mentioned total extract, stir evenly, then weigh the sucrose, citric acid, and honey in the formula and add them to the extract to adjust the flavor. After the best flavor, filter, and dilute the filtrate to 1000ml with purified water. The filtrate after constant volume is subjected to high-pressure homogenization treatment twice at a pressure of 40-50MPa and a temperature of 65°C, then ultrasonically degassed for 60 seconds in an ultrasonic instrument with a power of 500W and a frequency of 60KHz, and then sterilized at high temperature for 20-30min. The temperature was 121°C. Filling, inspection, and packaging are finished products.

Example 3:

The prescription of present embodiment Codonopsis health beverage is that every 1000ml beverage contains:

Codonopsis 20g, dried hawthorn fruit 20g, osmanthus 5g, wolfberry dried fruit 10g, inositol 600mg, taurine 0.5g, citric acid 10g, sucrose 20g, honey 25g, the rest is purified water. Weigh Codonopsis pilosula, hawthorn, and wolfberry according to the formula, wash them, and steam them at 92°C for 25 minutes, then weigh the osmanthus fragrans and mix them with the above raw materials, add 3 times the amount of pure water equivalent to the total raw materials, and extract with 600-800W microwave for 8 minutes. Then put it in a cooking pot, add pure water to 8 times the amount of the raw material, decoct for 120 minutes, and filter to obtain the filtrate. The medicinal dregs were added with purified water equivalent to 6 times the amount of raw materials, decocted for 60 minutes, filtered to obtain a filtrate, and the two filtrates were combined to obtain a total extract.

Weigh taurine and inositol according to the formula, dissolve them with a small amount of pure water, add them to the above-mentioned total extract, stir evenly, then weigh the sucrose, citric acid, and honey in the formula and add them to the extract to adjust the flavor. After the best flavor, filter, and dilute the filtrate to 1000ml with purified water. The filtrate after constant volume was subjected to high-pressure homogenization treatment twice at a pressure of 40-50MPa and a temperature of 55°C, then ultrasonically degassed for 45 seconds in an ultrasonic instrument with a power of 1000W and a frequency of 60KHz, and then sterilized at high temperature for 10s at a temperature of 140°C. Filling, inspection, and packaging are finished products.

Example 4:

1. Codonopsis pilosula health drink of the present invention relieves physical fatigue test

1.1 Materials and methods

1.1.1 Sample Codonopsis Codonopsis Health Beverage The original sample is a brown liquid with a density of about 1g/ml. After taking out the ineffective sucrose and citric acid from the sample, it was evaporated and concentrated 20 times under normal pressure, and the concentrated solution (with a density of about 1.2g/ml) was used as the test substance.

1.1.2 40 Kunming mice, male, weighing 18-22g, normal grade. purchased from the Experimental Animal Center of Lanzhou University. Immediately divided into 4 groups, respectively, weight-bearing swimming test, blood lactate measurement.

1.1.3 The dosages are 5 times, 10 times and 20 times of the recommended human dose, namely 30g/kg, 60g/kg and 120g/kg. A blank control group is also given the same volume of normal saline. The corresponding indicators were measured after continuous intragastric administration of the above four groups for 30 days.

1.1.4 Main instruments and reagents: ADVIA1200 automatic biochemical analyzer, lactic acid analyzer, swimming box.

1.1.5 Experimental method

1.1.5.1 Weight-bearing swimming test: 1 hour after the last administration of the test substance and normal saline, the mice were placed in a self-made swimming box with a water depth of not less than 30cm and a water temperature of 25±5°C with a lead sheet bearing 5% of their body weight on their tails. Swim, and record the time from the start of swimming to death of the mice.

1.1.2.2 Determination of blood lactic acid: 1 hour after the last administration of the test substance, 20 ul of blood was taken from the posterior orbital veins of the mice in the diluent, and the blood lactic acid content was measured with a lactate analyzer, and then placed in a water depth of 30 cm. Swim in a swimming tank with a water temperature of 25°C for 10 minutes. After swimming for 0 and 20 minutes, take 20ul of blood from the posterior orbital plexus and put it in the diluent to measure the blood lactic acid content.

1.1.6 Statistical software SPSSll.0 was used for data analysis, and the data were expressed as x±s. The measurement data were first tested by normal distribution and homogeneity of variance, and then analyzed by variance and t test.

1.2 Experimental results

1.2.1 The effect of Codonopsis health drink on the weight-bearing swimming time of mice is shown in Table 1:

Table 1

Dose g/kg Number of animals (only) Weight-bearing swimming time (min) P value Blank control group 10 30.1±11.3 30 10 46.2±9.7 0.412 60 10 50.3±14.7 0.015 120 10 59.6±10.1 0.001

It can be seen from Table 1 that the weight-bearing swimming time of the mice in the medium-dose and high-dose groups was significantly longer than that of the control group, and the difference was significant compared with the blank control group (p<0.05), suggesting that under the experimental conditions, Codonopsis Codonopsis Health Beverage can prolong the weight-bearing swimming time of mice .

1.2.3 The effect of Codonopsis Codonopsis Health Beverage on the blood lactic acid level of mice after exercise, as shown in Table 2:

Area under the blood lactic acid curve=1/2×(blood lactic acid value before swimming + blood lactic acid value 0 min after swimming)×10+1/2×(blood lactic acid value 0 min after swimming+blood lactic acid value 20 min after swimming)×20.

Table 2

Dose g/kg Number of animals (only) Area under the blood lactate curve P value Blank control group 10 148.4±19.1 30 10 137.7±12.8 0.512 60 10 132.9±19.1 0.031 120 10 110.5±16.7 0.001

It can be seen from Table 2 that the area under the curve of blood lactic acid in the middle dose and high dose groups was significantly smaller than that of the control group, and the difference was significant compared with the control group (p<0.05), suggesting that under the conditions of this experiment, Codonopsis Codonopsis Health Beverage can reduce blood lactic acid in mice. area under the curve.

2. Codonopsis Codonopsis Health Beverage Lowering Blood Fat Test of the present invention

2.1 Materials and methods

2.1.1 Animals Male SD rats, clean grade, weighing (150±10) g, were purchased from the Experimental Animal Center of Lanzhou University.

2.1.2 Drugs and reagents: Sample The original sample of Codonopsis Codonopsis Health Drink is a brown liquid with a density of about 1g/ml. After taking out the ineffective sucrose and citric acid from the sample, it was evaporated and concentrated 20 times under normal pressure, and the concentrated solution (with a density of about 1.2g/ml) was used as the test substance. Administration by intragastric administration, freshly prepared before use. Serum total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) assay kits were provided by Nanjing Jiancheng Reagent Company. Preparation of high-fat feed: 0.2% of bile salt, 8% of lard, 0.2% of propylthiouracil, 2% of cholesterol, and 89.6% of basic feed.

2.1.3 Animal model establishment and grouping After the rats were adapted to feeding for 1W, they were randomly divided into 6 groups, 10 in each group, respectively blank control group, high-fat model group, high, middle and low dose groups (15, 30, 60g) /kg). The blank control group was fed with standard feed, and the rest of the groups were fed with high-fat feed to create animal models of hyperlipidemia. They were fed continuously for 4 weeks, and blood lipid indexes were measured to confirm whether the model was successful or not. After the modeling was successful, intragastric administration was started, with a volume of 10ml/kg. The low, medium and high dose groups of the test substance were administered with 15, 30, and 60g/kg concentrations of the test substance solution respectively. The blank control group and the high-fat The model group was gavaged with equal volume of distilled water, once a day, and the rats in each group were free to eat and drink during the gavage period.

2.1.4 Determination of Experimental Indexes Before and after 4W animal modeling, the rats were fasted overnight, anesthetized with ether, and blood was collected from the retro-orbital venous plexus to measure TC and TG for model testing. After intragastric administration for a certain period of time, the rats were fasted overnight, blood was collected from the retro-orbital venous plexus, serum was separated, and serum TC, TG, HDL, and LDL were measured. All indicators were carried out according to the instructions of the kit. Blood was collected once at 2W, and all indicators were tested.

2.1.5 Statistical methods SPSSll.0 statistical software was used for data analysis, and the data were expressed as i±s. The measurement data were first tested by normal distribution and homogeneity of variance, and then analyzed by variance and t test.

2.2 Experimental results

2.2.1 The effects of Codonopsis health drink on serum TC and TG in hyperlipidemia rats are shown in Table 3:

table 3

Compared with the blank control group: * means P<0.01; compared with the model group: ^a means P<0.01.

2.2.2 The effect of Codonopsis health drink on serum LDL-C and HDL-C of hyperlipidemia rats, as shown in Table 4:

Table 4

Compared with the blank control group: * means P<0.01; compared with the model group: a means P<0.01.

It is suggested from Table 3 and Table 4 that under the conditions of this experiment, Codonopsis Codonopsis Health Beverage has inhibitory effect on hyperlipidemia in rats.

3. Experiments on dyspepsia in the general population:

Choose 25 dyspepsia crowds as the number of subjects, apply the health drink of Example 3 for 30 days, drink about 250-500ml per day, observe for 30 days, 20 people are markedly effective, 3 people are basically ineffective, and the total effective rate reaches 80%. Carry out the same experiment with embodiment 1 and 2, effect is identical with embodiment 3.

4. Blood pressure lowering experiments on the general population:

The subjects were people with a history of hypertension. The number of subjects was 30. They usually took antihypertensive drugs. Example 3 was quoted as a health drink for 30 days, and the drinking volume was about 250-500ml per day. After 30 days of observation, 25 people showed marked effects. , 3 people were basically invalid, and the total effective rate was 83%. Carry out the same experiment with embodiment 1 and 2, effect is identical with embodiment 3.

Finally, it should be noted that: the above is only a preferred embodiment of the present invention, and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still The technical solutions recorded in the foregoing embodiments may be modified, or some technical features thereof may be equivalently replaced. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the protection scope of the present invention.

Claims (7)

1. the dangshen health-care beverage is characterized in that, said prescription is to contain in every 1000ml dangshen health-care beverage:

Bright Radix Codonopsis 20-100g or codonopsis pilosula 5-30g, hawthorn fresh fruit 20-100g or hawthorn dry fruit 5-30g, sweet osmanthus 5-15g, medlar fresh fruit 0-100g or dried fruit of lycium barbarum 0-25g; Inositol 100-800mg, taurine 0.1-0.8g, citric acid 0-20g; Sucrose 0-25g, honey 0-30g, surplus is a pure water.

2. dangshen health-care beverage according to claim 1 is characterized in that, said prescription is to contain in every 1000ml dangshen health-care beverage:

Bright Radix Codonopsis 50-100g, hawthorn fresh fruit 50-100g, sweet osmanthus 5g, medlar fresh fruit 5-25g, inositol 300-600mg, taurine 0.2-0.6g, citric acid 5-10g, sucrose 10-20g, honey 10-25g, surplus is a pure water.

3. dangshen health-care beverage according to claim 1, its special this is that said prescription is to contain in every 1000ml dangshen health-care beverage:

Codonopsis pilosula 20-30g, hawthorn dry fruit 20-50g, sweet osmanthus 5-10g, dried fruit of lycium barbarum 0-25g, inositol 400-600mg, taurine 0.5-0.6g, citric acid 8-10g, sucrose 15-20g, honey 15-25g, surplus is a pure water.

4. according to the preparation method of the arbitrary described dangshen health-care beverage of claim 1-3, it is characterized in that, include following steps:

1) bright Radix Codonopsis, hawthorn dry fruit and dried fruit of lycium barbarum are taken by weighing according to prescription, and after 90-130 ℃ of steam treatment 5-30 minute, add the formula ratio sweet osmanthus, obtain mixed material; Or

Codonopsis pilosula, hawthorn fresh fruit and medlar fresh fruit are directly mixed with the formula ratio sweet osmanthus, obtain mixed material;

2) add in the mixed material that step 1) is obtained and be equivalent to the pure water of mixed material 1-3 times quality, and carry out Microwave Extraction, extraction conditions is micro-wave oven Microwave Extraction 5-15 minute of 200-800W, obtains the preliminary treatment compound;

3) with step 2) the preliminary treatment compound that obtains places cooker to decoct, and mends pure water to being equivalent to mixed material 5-10 times quality, decocts after 40-120 minute the 80-100 mesh sieve filter obtain filtrating one with expect slag;

4) the material slag that step 3) is obtained decocted 30-60 minute after placing cooker to add the pure water that is equivalent to mixed material 5-8 times, and the 80-100 mesh sieve filters and obtains filtrating two;

5) with step 3) filtrating one that obtains and filtrating two mixing that step 4) obtains, obtain total extract;

6) taurine and inositol are taken by weighing according to prescription; Add and join after a small amount of dissolved in purified water in total extract that step 5) obtains; The sucrose, citric acid and the honey that add formula ratio after stirring again, then the 80-100 mesh sieve filters; To filtrate again and be settled to 1000ml, obtain the two stage treatment compound with pure water;

7) the two stage treatment compound that step 6) is obtained is at pressure 40-50MPa; Temperature 40-80 ℃ is carried out after high pressure homogenizing handles 1-2 time; In power 100-1500W, carry out ultrasonic degas 30-120 second in the Ultrasound Instrument of frequency 40-100KHz, high-temperature sterilization 5-20s; Sterilising temp is 138-150 ℃, obtains the health drink semi-finished product;

8) step 7) is obtained the health drink semi-finished product and carry out can, check and packing, obtain the finished product of dangshen health-care beverage.

5. according to the preparation method of the arbitrary described dangshen health-care beverage of claim 1-3, it is characterized in that, include following steps:

1) the hawthorn fresh fruit is cleaned the back section, thickness is 1-5mm, and codonopsis pilosula is cleaned the back segment, and length is 1-3cm, obtains mixed material after codonopsis pilosula, hawthorn fresh fruit and sweet osmanthus are mixed with formula ratio;

2) add when in the pure water of 2 times of amounts of raw material gross weight, and carry out Microwave Extraction, extraction conditions is the micro-wave oven Microwave Extraction 10 minutes of 500W, obtains the preliminary treatment compound;

3) with step 2) the preliminary treatment compound that obtains places cooker to carry out boiling, and mends pure water to being equivalent to 5 times of quality of mixed material, decocts after 60 minutes the 80-100 mesh sieve filter obtain filtrating one with expect slag;

4) the material slag that step 3) is obtained decocted 40 minutes after placing cooker to add the pure water that is equivalent to 5 times of mixed materials, filtered and obtained filtrating two, and filtering the order number is the 80-100 order;

5) with step 3) filtrating one that obtains and filtrating two mixing that step 4) obtains, obtain total extract;

6) taurine and inositol are taken by weighing according to prescription; Add and join after a small amount of dissolved in purified water in total extract that step 5) obtains; Add sucrose, citric acid and the honey of formula ratio after stirring again, then filter, filtering the order number is the 80-100 order; To filtrate again and be settled to 1000ml, obtain the two stage treatment compound with pure water;

7) the two stage treatment compound that step 6) is obtained is at pressure 45MPa, and 80 ℃ of temperature are carried out after high pressure homogenizing handles 2 times, in power 100W; Carried out ultrasonic degas in the Ultrasound Instrument of frequency 40KHz 60 seconds; High-temperature sterilization 5s, sterilising temp is 140-150 ℃, obtains the health drink semi-finished product;

8) step 7) is obtained the health drink semi-finished product and carry out can, check and packing, obtain the finished product of dangshen health-care beverage.

6. according to the preparation method of the arbitrary described dangshen health-care beverage of claim 1-3, it is characterized in that, include following steps:

1) bright Radix Codonopsis, hawthorn dry fruit and dried fruit of lycium barbarum are taken by weighing according to prescription, and add the formula ratio sweet osmanthus after 25 minutes, obtain mixed material in 100 ℃ of steam treatment; Or

Codonopsis pilosula, hawthorn fresh fruit and medlar fresh fruit are directly mixed with the formula ratio sweet osmanthus, obtain mixed material;

2) add when in the pure water of 2 times of amounts of raw material gross weight, and carry out Microwave Extraction, extraction conditions is micro-wave oven Microwave Extraction 5-15 minute of 500W, obtains the preliminary treatment compound;

3) with step 2) the preliminary treatment compound that obtains places cooker to carry out boiling, and mends pure water to being equivalent to mixed material 5-8 times quality, decocts after 40-120 minute the 80-120 mesh sieve filter obtain filtrating one with expect slag;

4) the material slag that step 3) is obtained decocted 30-60 minute after placing cooker to add the pure water that is equivalent to mixed material 5-6 times, filtered and obtained filtrating two, and filtering the order number is the 80-120 order;

5) with step 3) filtrating one that obtains and filtrating two mixing that step 4) obtains, obtain total extract;

6) taurine and inositol are taken by weighing according to prescription; Add and join after a small amount of dissolved in purified water in total extract that step 5) obtains; Add sucrose, citric acid and the honey of formula ratio after stirring again, then filter, filtering the order number is the 80-120 order; To filtrate again and be settled to 1000ml, obtain the two stage treatment compound with pure water;

7) the two stage treatment compound that step 6) is obtained is at pressure 40-50MPa, and 65 ℃ of temperature are carried out after high pressure homogenizing handles 2 times, in power 500W; Carried out ultrasonic degas in the Ultrasound Instrument of frequency 60KHz 60 seconds; High-temperature sterilization 20-30min, sterilising temp is 121 ℃, obtains the health drink semi-finished product;

8) step 7) is obtained the health drink semi-finished product and carry out can, check and packing, obtain the finished product of dangshen health-care beverage.

7. according to the preparation method of the arbitrary described dangshen health-care beverage of claim 1-3, it is characterized in that, include following steps:

1) bright Radix Codonopsis, hawthorn dry fruit and dried fruit of lycium barbarum are taken by weighing according to prescription, and add the formula ratio sweet osmanthus after 25 minutes, obtain mixed material in 92 ℃ of steam treatment; Or

Codonopsis pilosula, hawthorn fresh fruit and medlar fresh fruit are directly mixed with the formula ratio sweet osmanthus, obtain mixed material;

2) add when in the pure water of 3 times of amounts of raw material gross weight, and carry out Microwave Extraction, extraction conditions is the micro-wave oven Microwave Extraction 8 minutes of 600-800W, obtains the preliminary treatment compound;

3) with step 2) the preliminary treatment compound that obtains places cooker to carry out boiling, and mends pure water to being equivalent to 8 times of quality of mixed material, decocts after 120 minutes the 80-100 mesh sieve filter obtain filtrating one with expect slag;

4) the material slag that step 3) is obtained decocted 60 minutes after placing cooker to add the pure water that is equivalent to 6 times of mixed materials, filtered and obtained filtrating two, and filtering the order number is the 80-100 order;

5) with step 3) filtrating one that obtains and filtrating two mixing that step 4) obtains, obtain total extract;

6) taurine and inositol are taken by weighing according to prescription; Add and join after a small amount of dissolved in purified water in total extract that step 5) obtains; Add sucrose, citric acid and the honey of formula ratio after stirring again, then filter, filtering the order number is the 80-120 order; To filtrate again and be settled to 1000ml, obtain the two stage treatment compound with pure water;

7) the two stage treatment compound that step 6) is obtained is at pressure 40-50MPa, and 55 ℃ of temperature are carried out after high pressure homogenizing handles 2 times, in power 1000W; Carried out ultrasonic degas in the Ultrasound Instrument of frequency 60KHz 45 seconds; High-temperature sterilization 10s, sterilising temp is 140 ℃, obtains the health drink semi-finished product;

8) step 7) is obtained the health drink semi-finished product and carry out can, check and packing, obtain the finished product of dangshen health-care beverage.