CN102406899B - 治疗乳腺增生的中药制剂 - Google Patents
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Abstract
本发明属于中药制剂领域，特别涉及一种治疗乳腺增生的中药制剂，由如下重量份数的中药原料制成：柴胡5份、郁金3份、丹参4份、山楂5份、白芍3份、元参3份和香附3份，具有疏肝理气、活血祛瘀的功效。本发明是在传统的中医辩证施治的基础上结合临床实践研制而成，治疗乳腺增生具有疗效显著、治愈率高、无毒副作用、安全方便的特点。
Description
技术领域
本发明属于中药制剂领域，特别涉及一种治疗乳腺增生的中药制剂。
背景技术
乳腺增生是妇女的常见病，属中医“乳癖”范畴，患者一侧或两侧乳腺内可触及多个大小不一的结节，多散在或融合成不规则的团块，质韧、稍硬、有压痛，与皮肤及深部组织之间无粘连，可被推动。临床表现为患侧乳腺常感坠胀不舒、疼痛，多与月经周期有关，有的患者月经来潮前症状加重，常伴有心烦易怒、失眠等。现代医学认为本病的发病原因与卵巢机能失调有关，黄体素与雌激素的比例失去平衡，黄体素分泌减少，雌激素的量相对增多；中医认为本病的发病机理是肝气郁结、冲任失调、气滞血瘀。中医采取疏肝理气、活血祛瘀的方法治疗该病，取得了较好的治疗效果，发明一种既安全又有效的中药制剂十分必要。
发明内容
本发明所要解决的技术问题是提供一种治疗乳腺增生的中药制剂，具有疗效显著、见效快、治愈率高、无毒副作用、安全方便的特点。
本发明一种治疗乳腺增生的中药制剂，其特征在于由如下重量份数的中药原料制成：柴胡5份、郁金3份、丹参4份、山楂5份、白芍3份、元参3份和香附3份。
本发明可以制成中药学上可接受的各种制剂，优选丸剂。
制备方法：将上述药物炮制合格、称量配齐，共轧为细粉、和匀、过80～100目细罗；取炼蜜26份(炼蜜时蜜温120℃，和药时蜜温90℃)与上述药粉搅拌均匀成滋润团块、分坨、搓条制丸，每丸重9克，用蜡纸包严，入盒密封。
用法及用量：口服，一次一丸，日服三次，20天为一疗程。
本发明药物机理如下：
柴胡：疏散退热、疏肝解郁、升举阳气，本品味辛苦、气微寒、芳香疏泄，能条达肝气、疏肝解郁、调经止痛，对于胸胁疼痛，不论内伤肝郁、外伤跌扑均可应用。
郁金：活血行气止痛、解郁清心、利胆退黄、凉血。本品味辛，能行能散，既能活血又能行气解郁而止痛。
丹参：活血调经、凉血消痛、安神。本品性寒，凉血又能活血，清瘀热而散结，为活血化瘀的要药。
山楂：消食化积、行气散瘀，本品性温能通行气血，有活血祛瘀止痛之功，临床中常用于瘀阻胸腹疼痛等症。
白芍：益血调经、平肝止痛、敛阴止汗。
元参：清热凉血、滋阴解毒。
香附：疏肝理气、调经止痛，本品辛能通行、苦能疏泄，微甘缓急，为疏肝解郁、行气止痛的要药，临床中常用于月经不调、乳房胀痛等病症。
疗效判断：
痊愈：自觉症状完全消失，全身无阳性体征可查。
好转：自觉症状基本消失，偶感月经来潮时乳腺略有胀痛，月经过后症状消失，乳房结节明显缩小、质软、无触痛。
无效：症状无改善。
治疗结果：治疗乳腺增生患者85例，服用实本发明丸剂，一次一丸，日服三次，20天为一个疗程。经三个疗程治疗，痊愈48例，占56％，好转26例，占31％，无效11例，占13％，总有效率87％。通过治疗所示，对病人无任何副作用，三大常规化验及肝肾功能检测未发现异常。
以下列举几个典型病例：
病例1：患者王某某，女，37岁，患乳腺增生，两侧乳房胀痛、有肿块，曾服中西药物、理疗等治疗半年无好转，后经口服本发明药物三个疗程后，症状全部消失，全身无阳性体征可查，随访一年无复发。
病例2：患者刘某某，女，40岁，患乳腺增生，乳房内有黄豆大肿块，痛如针刺，月经来潮加重，服用本发明药物三个疗程后痊愈，随访一年无复发。
病例3：患者张某某，女，42岁，患乳腺增生两年余，多方治疗无效，经服用本发明药物三个疗程后痊愈，随访一年无复发。
本发明有如下优点：
本发明是在传统的中医辩证施治的基础上结合临床实践研制而成的，诸药相合共具有疏肝理气、活血祛瘀的功效，治疗乳腺增生具有疗效显著、见效快、治愈率高、无毒副作用的特点。
具体实施方式
以下结合实施例对本发明做进一步描述。
实施例
丸剂，按重量份数称取原料：柴胡5份、郁金3份、丹参4份、山楂5份、白芍3份、元参3份和香附3份。
制备方法：将上述药物炮制合格、称量配齐，共轧为细粉、和匀、过80～100目细罗；取炼蜜26份(炼蜜时蜜温120℃，和药时蜜温90℃)与上述药粉搅拌均匀成滋润团块、分坨、搓条制丸，每丸重9克，用蜡纸包严，入盒密封。
Claims (1)
1.一种治疗乳腺增生的中药制剂，其特征在于由如下重量份数的原料制成：柴胡5份、郁金3份、丹参4份、山楂5份、白芍3份、元参3份和香附3份；
制备方法：将上述药物炮制合格、称量配齐，共轧为细粉、和匀、过80～100目细罗；取炼蜜26份与上述药粉搅拌均匀成滋润团块、分坨、搓条制丸，每丸重9克，用蜡纸包严，入盒密封；其中，炼蜜时蜜温120℃，和药时蜜温90℃。
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| CN104147152B (zh) * | 2014-07-19 | 2016-10-19 | 云南荣之健生物科技有限公司 | 石榴果精油水凝胶贴及其制作方法 |
| CN105288503A (zh) * | 2015-12-03 | 2016-02-03 | 苏州枫灵医药科技有限公司 | 一种用于治疗乳癖的药物制剂 |
| CN105381419A (zh) * | 2015-12-28 | 2016-03-09 | 范明月 | 一种治疗乳腺增生的中药膏剂 |
| CN116570698A (zh) * | 2023-06-05 | 2023-08-11 | 长春中医药大学 | 一种用于治疗肝郁气滞型乳腺增生症的中药组合物 |
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| JP2599159B2 (ja) * | 1987-12-26 | 1997-04-09 | 日清製粉株式会社 | 牛の乳房炎の予防及び治療剤 |
| CN1299736C (zh) * | 2004-07-26 | 2007-02-14 | 耿新生 | 治疗乳腺增生的中药胶囊及其生产方法 |
| WO2009062338A1 (fr) * | 2007-11-14 | 2009-05-22 | Shangxian Gao | Médicament chinois lactogène destiné au traitement et à la prévention de maladies gynécologiques, procédés de préparation et utilisations de celui-ci |
| CN102178896B (zh) * | 2011-04-28 | 2012-09-05 | 时红霞 | 一种治疗乳腺增生的中药组合物及其制备方法 |
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Effective date of registration: 20190123 Address after: No. 1 Huayangang, Gulou District, Nanjing City, Jiangsu Province, 210000 Patentee after: NANJING YIMEI BIOTECHNOLOGY Co.,Ltd. Address before: 226500 Xiayuan Community Residential Committee, Xiayuan Town, Rugao City, Jiangsu Province Patentee before: Rugao lower primary hospital |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140219 |
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| CF01 | Termination of patent right due to non-payment of annual fee |