CN102397294A - Effects of invigorating yang and tonifying sperm and preparation method of composition extracted from zygote - Google Patents

Effects of invigorating yang and tonifying sperm and preparation method of composition extracted from zygote Download PDF

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Publication number
CN102397294A
CN102397294A CN2010102743918A CN201010274391A CN102397294A CN 102397294 A CN102397294 A CN 102397294A CN 2010102743918 A CN2010102743918 A CN 2010102743918A CN 201010274391 A CN201010274391 A CN 201010274391A CN 102397294 A CN102397294 A CN 102397294A
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China
Prior art keywords
compositions
composition
effect
effects
sexual
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Pending
Application number
CN2010102743918A
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Chinese (zh)
Inventor
丁庆
大石一二三
吉田博雅
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Individual
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Individual
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Priority to CN2010102743918A priority Critical patent/CN102397294A/en
Publication of CN102397294A publication Critical patent/CN102397294A/en
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Abstract

The invention discloses a composition which has effects of invigorating yang and tonifying sperm. The composition comprises water extract or butanol extract of fertilized egg yolks of birds or reptile as main components and has the effect of improving sexual dysfunction. The composition extracted from the fertilized egg yolks of birds or reptile, has the effect of promoting physiological erection mechanism, and has wide effect of improving idiopathic sexual dysfunction.

Description

Extraction is from the tonifying YANG of the compositions of germ cell and strong smart effect and preparation method thereof
The invention relates to extraction and water extract or the butanol extract of smart ovum pharmaceuticals compositions or the diet article compositions as effective ingredient arranged from birds and reptiles.
From the youth to person in middle and old age's layer stage, the age level of wide scope, sexual dysfunction person's increase phenomenon has been able to confirm.Traditional theory is thought sexual dysfunction with old and feeble relevant, still from recent years sexual dysfunction person's increase situation, only explains it is comprehensive inadequately with this saying, so there is the people to propose " endogenous cause of ill ".On the other hand, the someone has proposed " organic sexual dysfunction is relevant with diabetes and atherosclerosis " this viewpoint; The former is owing to the peripheral nerve pathological changes, and the latter then is because due to the circulatory disorders.Male genital organ erect be according to sexual stimulus from the nitric oxide synthetase product (NO) that vascular endothelial cell produces, increased Saikurikkuguanoshinmono phosphagen (cGMP) and the result of blood flow increase in the level and smooth muscle of male genital organ spongy body.Therefore, as the improvement measure of sexual dysfunction,, can adjust the amount of the oxytocin (OT) and the Dobamin (DO) of mesencephalic centre from the endogenous cause of ill aspect; From organic aspect, can improve peripheral nervous and peripheral blood and flow, promote the NO of vascular endothelial cell to generate.'Xiduofeng ' is the representative drugs that is used to the sexual function improving obstacle, and the mechanism of action of 'Xiduofeng ' comes to hinder and decomposes cancellation Hosufojiesuteraze cGMP.But these medicines do not have Yang-strengthening effect, and its mechanism of action has increased the burden of causing circulatory (heart and blood pressure) on the contrary, and its safety waits research.
Since ancient times, as the thing of improvement with sexual dysfunction and yang invigorating functions, the many compositions in the animals and plants of distributed in nature and the insecticide are able to utilize.After nitric oxide synthetase product (NO) came to light, the eicosapentaenoic acid of natural prodcuts, docosahexenoic acid and arginine also were utilized time and again.Yet the effectiveness of all these things all is not able to science to be proved, so securely and effectively the compositions of sexual function improving obstacle becomes the market demand.
The present invention has safe tonifying YANG and strong smart effect, and purpose is to have the compositions of improving effect for the sexual dysfunction person provides.The inventor is in order to solve the problem of similar front, on the basis of inquiring into keen determination, in the germ cell as the birds of general food and reptiles, successfully found to have the composition that sexual dysfunction improves effect, accomplished the present invention.That is to say that the present invention is included in the metabolite that produces in the fertilized egg hatching process of birds and reptiles or biosynthesis thing interior, the compositions with tonifying YANG, strong smart effect of water or butyl alcohol extraction.
The smart ovum that has of birds used in the present invention is that the poultry that is easy to obtain has smart ovum, and the smart ovum that has of reptiles also is the smart ovum that has of the Trionyx sinensis Wiegmann that obtains easily.These egg yolk lyophilizations that smart ovum is arranged, after the defats such as reuse organic solvent, water or butanols extract.Extract as xeraphium or powdered extract powder can be formulated into compositions.
In the present composition; Can allocate those and be added to the composition in food or the pharmaceuticals usually; Like glucose, lactose, sucrose, starch, cellulose, sugar alcohol and dextrin etc.; Also can add Semen Tritici aestivi germ oil, Oleum Vitis viniferae, rice embryo oil and plant wet goods, and Cera Flava, hydrogenation wet goods wax composition, and even more soybean lecithin, Ovum Gallus domesticus Flavus lecithin and other phospholipid etc.
Compositions of the present invention can suitably be processed tablet, capsule, powder, granule, can adopt common preparation way.Composition of the present invention is the composition that contains egg yolk that has edible and added by food, comprises that the compositions of the present invention that contains these compositions is safe, can feel at ease to absorb, take.Compositions of the present invention can be absorbed 0.1~20 gram usually once a day.According to applicable object, symptom etc., intake can suitably be adjusted.
Compositions of the present invention has tonifying YANG, improves the effect of erecing, and can improve male's sexual.Compositions of the present invention is sent out the sexual function obstacle for the spy, according to optimizing endogenous maincenter OT, DO, demonstrates the effectiveness of broad range.
The specific embodiment
Modulation example 1
Hatched the 9th day, and got the egg yolk 100g that smart ovum is arranged of chicken, remove after the membrane of yolk, do not destroying in the water of particulate situation low suspension in equivalent.With its lyophilization, obtain the dry thing of 40g.After the acetone dehydration,, obtain the de-fatted egg yolk of 15g with chloroform methanol (with 1: 1) defat.Add the deionized water of 1000ml here, and stir and extracted 48 hours.Water extract pasteurization (85 ℃, 10 minutes) afterwards, lyophilization.Obtain the dry thing of 3g.
Modulation example 2
The Trionyx sinensis Wiegmann that use was hatched the 6th day smart ovum arranged, other modulator approaches with example 1 are identical.
Modulation example 3
In the de-fatted egg yolk that the method for the example of having described 1 is obtained, add the butanols of 1000ml, and stir and extracted 48 hours.The butanols of extracting solution under reduced pressure (Rotariepaboreta) is removed, and adds water in the residue, filters insoluble matter, obtains the hydrotrope.With its lyophilization, obtain the dry thing of 2g.
Modulation example 4
Utilize the same Trionyx sinensis Wiegmann of using in the example 2 that smart ovum is arranged, modulator approach and the example of having described 3 methods are with identical
Test Example 1
Object is the male (34 years old-65 years old) of all sexual dysfunctions, and continuous three days, orally ingestible was modulated each 0.5g of routine 1-4 once a day.Any one of effect usefulness " erectile ability " and " could carry out in the sexual behaviour " declared the oneself and judged.Not erecing empirical volunteer more than 1 year fully as subjects at each.In going to bed according to the testee or some factors of sexual stimulus etc. cause the situation conduct of erection+, unresponsive situation as-, declare by experimenter oneself about having or not equally of sexual behaviour then.
The result of table 1. modulation example 1
Subjects That erects has or not Having or not of sexual behaviour
A + -
B + -
C + +
D + +
E + +
The result of table 2. modulation example 2
Subjects That erects has or not Having or not of sexual behaviour
A + -
B + +
C + +
D + +
E + +
The result of table 3. modulation example 3
Subjects That erects has or not Having or not of sexual behaviour
A + -
B + +
C + +
D + +
E + +
The result of table 4. modulation example 4
Subjects That erects has or not Having or not of sexual behaviour
A + -
B + +
C + +
D + +
E + +
See that from the result of table 1-4 the powder of modulation example not only can improve erectile ability, has also shown the yang invigorating functions that promotes that actual sexual behaviour is desired to ask.The situation of subjects A, the sexual behaviour in this duration of test is not admitted.About this, subjects is described, because the companion also is the reason at advanced age, does not have behavior.
As stated, composition of the present invention is people's compositions edible usually or that in food, be added usually, can feel at ease to absorb, take.And, can see clearly that like above-mentioned Test Example compositions of the present invention has the remarkable effect of improving for sexual dysfunction, be safe tonifying YANG and strong smart compositions or food.

Claims (4)

1. tonifying YANG and the strong smart compositions of the water extract of the birds germ cell that has in the process of hatching as effective ingredient.
2. tonifying YANG and the strong smart compositions of the butanol extract of the birds germ cell that has in the process of hatching as effective ingredient.
3. tonifying YANG and the strong smart compositions of the water extract of the reptiles germ cell that has in the process of hatching as effective ingredient.
4. tonifying YANG and the strong smart compositions of the butanol extract of the reptiles germ cell that has in the process of hatching as effective ingredient.
CN2010102743918A 2010-09-07 2010-09-07 Effects of invigorating yang and tonifying sperm and preparation method of composition extracted from zygote Pending CN102397294A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010102743918A CN102397294A (en) 2010-09-07 2010-09-07 Effects of invigorating yang and tonifying sperm and preparation method of composition extracted from zygote

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010102743918A CN102397294A (en) 2010-09-07 2010-09-07 Effects of invigorating yang and tonifying sperm and preparation method of composition extracted from zygote

Publications (1)

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CN102397294A true CN102397294A (en) 2012-04-04

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1098625A (en) * 1992-07-29 1995-02-15 迈特福斯克食品研究院 The compositions of sexual function improving
CN1123557A (en) * 1994-02-21 1996-05-29 沃纳·C·诺罗基 Process for obtaining high-purity egg oil and use thereof
CN1394640A (en) * 2002-07-23 2003-02-05 深圳市汇华生命科技有限公司 Compound containing animal embryo extract with action of regulating immunologic function
CN1575801A (en) * 2003-07-28 2005-02-09 关令华 Crocodile embryo extract

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1098625A (en) * 1992-07-29 1995-02-15 迈特福斯克食品研究院 The compositions of sexual function improving
CN1123557A (en) * 1994-02-21 1996-05-29 沃纳·C·诺罗基 Process for obtaining high-purity egg oil and use thereof
CN1394640A (en) * 2002-07-23 2003-02-05 深圳市汇华生命科技有限公司 Compound containing animal embryo extract with action of regulating immunologic function
CN1575801A (en) * 2003-07-28 2005-02-09 关令华 Crocodile embryo extract

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Application publication date: 20120404