CN102357225A - Traditional Chinese medicine composition for curing insomnia - Google Patents

Traditional Chinese medicine composition for curing insomnia Download PDF

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CN102357225A
CN102357225A CN2011103341574A CN201110334157A CN102357225A CN 102357225 A CN102357225 A CN 102357225A CN 2011103341574 A CN2011103341574 A CN 2011103341574A CN 201110334157 A CN201110334157 A CN 201110334157A CN 102357225 A CN102357225 A CN 102357225A
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chinese medicine
traditional chinese
medicine composition
insomnia
angelica
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柳晖
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Quantum Dental Technologies Inc
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Abstract

The invention relates to a traditional Chinese medicine composition for curing insomnia, which comprises the following traditional Chinese medicine raw materials in weight ratio: 10-40 g of ginseng, 10-40 g of largehead atractylodes rhizome, 10-40 g of Astragalus mongholicus, 5-25 g of Chinese angelica, 5-30 g of poria with hostwood, 5-25 g of polygala tenuifolia, 10-40 g of fried Chinese date kernel, 5-30 g of dens draconis, 5-30 g of fructus amomi, 10-40 g of cuttle bone, 5-25 g of dried tangerine or orange peel, 5-25 g of elecampane, 5-15 g of Pinellia ternate, 5-30 g of radix angelicae, and 5-20 g of radix glycyrrhizae preparata. The traditional Chinese medicine composition disclosed by the invention has effects of tonifying qi, strengthening exterior, promoting blood circulation, removing obstruction in channels, soothing the liver, repelling melancholia, calming the heart and tranquilizing the mind and has an obvious curative effect for curing insomnia; and the traditional Chinese medicine composition is wide in medicinal source, simple and convenient to prepare, low in cost and gentle in medicine property and does not have toxic and side effects.

Description

一种治疗失眠的中药组合物A kind of traditional Chinese medicine composition for treating insomnia

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技术领域 technical field

本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗失眠的中药组合物。 The invention relates to a medical preparation of undetermined structure of traditional herbal medicine, especially a traditional Chinese medicine composition for treating insomnia.

背景技术 Background technique

失眠是指无法入睡或无法保持睡眠状态,导致睡眠不足。又称入睡和维持睡眠障碍(DlMS),为各种原因引起入睡困难、睡眠深度或频度过短、早醒及睡眠时间不足或质量差等,常见导致失眠的原因主要有环境原因、个体因素、躯体原因、精神因素、情绪因素等。失眠的危害严重,轻者会直接影响第二天的工作与学习,精神萎靡,疲惫无力,情绪不稳,注意力不集中。重者会引起感知方面变化,如视野变化、幻视、免疫功能降低、消化功能和性功能减退、记忆力下降、脾气变得敏感暴躁、性格改变。同时失眠易诱发高血压、冠心病、中风、糖尿病,妇女导致皮肤干燥、月经失调等疾病。目前,对失眠的治疗有心理治疗、物理治疗和药物治疗等方法。心理治疗是通过解释、指导,使患者了解有关睡眠的基本知识,减少不必要的预期性焦虑反应。物理治疗通常都是采取用磁疗治疗方法,可起到通络活血,消炎镇痛和镇静安眠的作用。药物治疗大多采用的是安眠药物。其存在着心理治疗、物理治疗效果不理想及安眠药物副作用大,长期服用安眠药,易出现药物依赖、过度镇静后感知能力下降、脏器受损等不足。 Insomnia is the inability to fall asleep or stay asleep, resulting in a lack of sleep. Disorders of falling asleep and maintaining sleep (DlMS), also known as sleep onset and maintenance disorders (DlMS), are caused by various reasons, such as difficulty in falling asleep, too short sleep depth or frequency, early awakening, insufficient sleep time or poor quality, etc. Common causes of insomnia mainly include environmental factors and individual factors , physical factors, mental factors, emotional factors, etc. The harm of insomnia is serious, and mild person can directly affect the work and study of next day, one's spirits are drooping, exhaustion is unable, emotional instability, inattention. In severe cases, it will cause changes in perception, such as visual field changes, hallucinations, decreased immune function, decreased digestive and sexual functions, decreased memory, sensitive and irritable temper, and personality changes. At the same time, insomnia can easily induce high blood pressure, coronary heart disease, stroke, diabetes, and women can cause dry skin, menstrual disorders and other diseases. At present, there are methods such as psychotherapy, physical therapy and drug therapy to the treatment of insomnia. Psychotherapy is to enable patients to understand the basic knowledge about sleep and reduce unnecessary anticipatory anxiety reactions through explanation and guidance. Physiotherapy usually adopts magnetic therapy treatment method, which can play the role of dredging collaterals, activating blood circulation, anti-inflammatory and analgesic, and calming and sleeping. Drug treatment mostly adopts sleeping pills. It has the disadvantages of unsatisfactory effects of psychotherapy and physical therapy and large side effects of sleeping pills. Long-term use of sleeping pills is prone to drug dependence, decreased perception after excessive sedation, and organ damage.

中医认为,失眠的病因病机以七情内伤为主要病因,其涉及的脏腑不外心、脾、肝、胆、肾,其病机总属营卫失和,阴阳失调为病之本,或阴虚不能纳阳,或阳盛不得入阴。若情志不舒,思虑过度,影响肝之疏泄,出现肝郁气滞,化火扰神,而耗伤心血,损伤脾运,心肾失交,神志不宁,致使五脏俱虚。 According to traditional Chinese medicine, the etiology and pathogenesis of insomnia are mainly due to the internal injuries of the seven emotions, and the viscera involved are nothing but the heart, spleen, liver, gallbladder, and kidney. Deficiency of yin cannot accept yang, or excess of yang cannot enter yin. If the mood is not comfortable, overthinking will affect the dredging and venting of the liver, stagnation of liver qi and stagnation of qi will occur, turning fire and disturbing the mind, consuming heart blood, impairing spleen transportation, heart-kidney disconnection, restless mind, resulting in deficiency of five viscera.

根据中医理论,针对失眠的发病机理,进行辩证配伍组方,以达到标本兼治的目的。 According to the theory of traditional Chinese medicine, according to the pathogenesis of insomnia, dialectical compatibility prescriptions are carried out to achieve the purpose of treating both symptoms and root causes.

发明内容 Contents of the invention

为了克服现有的西医治疗失眠的效果不佳及副作用大的不足,本发明提供一种配制方便、药源广、疗效显著、无副作用的一种治疗失眠的中药组合物。 In order to overcome the insomnia ineffectiveness and side effects of the existing Western medicine, the present invention provides a traditional Chinese medicine composition for treating insomnia which is convenient to prepare, has a wide range of medicine sources, has significant curative effect and has no side effects.

本发明解决其技术问题所采用的技术方案是:一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参10~40g、焦白术10~40g、黄芪10~40g、当归5~25g、茯神5~30g、远志5~25g、炒枣仁10~40g、龙齿5~30g、砂仁5~30g、乌贼骨10~40g、陈皮5~25g、木香5~25g、半夏5~15g、白芷5~30g、炙甘草5~20g。 The technical solution adopted by the present invention to solve the technical problem is: a traditional Chinese medicine composition for treating insomnia, characterized in that it is composed of the following traditional Chinese medicine raw materials in the following weight ratio: ginseng 10-40g, Jiaobaizhu 10-40g, Radix Astragalus 10-40g, Angelica 5-25g, Fushen 5-30g, Polygala 5-25g, Fried jujube kernel 10-40g, Dragon teeth 5-30g, Amomum 5-30g, Cuttlefish bone 10-40g, Tangerine peel 5-25g, Woody 5-25g, Pinellia 5-15g, Angelica dahurica 5-30g, Zhigancao 5-20g.

本发明的优先技术方案是:一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参30g、焦白术30 g、黄芪30g、当归15g、茯神20g、远志15g、炒枣仁30g、龙齿20g、砂仁20g、乌贼骨30g、陈皮15g、木香12g、半夏10g、白芷20g、炙甘草10g。 The preferred technical solution of the present invention is: a traditional Chinese medicine composition for treating insomnia, which is characterized in that it is composed of the following traditional Chinese medicine raw materials in the following weight ratio: ginseng 30g, Jiaobaizhu 30g, astragalus 30g, angelica 15g, Fushen 20g , Polygala 15g, Fried Jujube Kernel 30g, Dragon Tooth 20g, Amomum 20g, Cuttlefish Bone 30g, Tangerine Peel 15g, Woody Fragrance 12g, Pinellia 10g, Angelica dahurica 20g, Zhigancao 10g.

本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:人参具有大补元气、复脉固脱、补脾益肺的功效;焦白术具有健脾益气、燥湿止汗的功效;黄芪具有补肺健脾、益气固表、利水消肿的功效;当归具有补血活血、调经止痛的功效;茯神具有宁心安神、健脾利温的功效;远志具有安神益智、祛痰镇惊、行气散郁的功效;炒枣仁具有养肝敛汗、宁心安神的功效;龙齿具有镇惊安神、清热除烦的功效;砂仁具有化湿开胃、温脾理气的功效;乌贼骨具有去寒通经、收敛固精的功效;陈皮具有健脾开胃、行气宽中、燥湿化痰的功效;木香具有理气疏肝、散郁开结、健脾消滞的功效;半夏具有燥湿化痰、消痞散结的功效;白芷具有解表散寒、祛风通窍、活血燥湿的功效;炙甘草具有通阳和胃、滋阴补脾、益气复脉的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏益气固表、活血通络、疏肝散郁、宁心安神之功,促使腠理疏松、经脉调和、气血流畅,从而达到治疗失眠的目的。 The traditional Chinese medicine composition of the invention is a prescription of selected medicines under the guidance of traditional Chinese medicine theory and clinical experience. In the traditional Chinese medicine composition of the present invention: ginseng has the effects of invigorating vital energy, recovering veins and strengthening the spleen, nourishing the spleen and benefiting the lungs; The effect of diuresis and water swelling; Angelica has the effect of enriching blood and promoting blood circulation, regulating menstruation and relieving pain; Fushen has the effect of calming the mind, calming the nerves, invigorating the spleen and benefiting temperature; Polygala has the effect of calming the mind, eliminating phlegm, relieving convulsions, promoting qi and dispelling depression; Stir-fried jujube kernels have the effects of nourishing the liver and suppressing sweat, calming the mind and calming the nerves; dragon teeth have the effects of calming convulsions and calming the nerves, clearing heat and eliminating troubles; The effect of solidifying essence; tangerine peel has the effect of invigorating the spleen and appetizing, promoting qi and widening the middle, drying dampness and resolving phlegm; The effect of dispelling lumps and dissipating stagnation; Angelica dahurica has the effects of relieving the exterior and dispelling cold, expelling wind and clearing the orifices, promoting blood circulation and drying dampness; roasted licorice has the effects of promoting yang and harmonizing the stomach, nourishing yin and nourishing the spleen, and replenishing qi and restoring the pulse. The medicinal components in the composition of the present invention are dialectically compatible, complement each other in action, and have a synergistic effect. Reconciliation, qi and blood flow, so as to achieve the purpose of treating insomnia.

本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。本发明遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,药性平和,安全可靠,无毒副作用,有效率达96%。 The components of the composition of the invention all adopt natural traditional Chinese medicine raw materials, and the preparation is simple, the medicine source is wide, and the cost is low. The invention follows the principle of prescription medication in traditional Chinese medicine, and the various component medicines are taken by decoction. It has been verified by clinical application that it has remarkable curative effect, mild medicinal property, safety and reliability, no toxic and side effects, and the effective rate reaches 96%.

具体实施方式 Detailed ways

下面结合实施例对本发明做进一步说明。 The present invention will be further described below in conjunction with embodiment.

实施例1 Example 1

一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参30g、焦白术30 g、黄芪30g、当归15g、茯神20g、远志15g、炒枣仁30g、龙齿20g、砂仁20g、乌贼骨30g、陈皮15g、木香12g、半夏10g、白芷20g、炙甘草10g。 A traditional Chinese medicine composition for treating insomnia, characterized in that it is composed of the following traditional Chinese medicine raw materials in the following weight ratio: ginseng 30g, Jiaobaizhu 30g, astragalus 30g, angelica 15g, Fushen 20g, polygala 15g, fried jujube kernel 30g , Dragon tooth 20g, amomum 20g, cuttlefish bone 30g, tangerine peel 15g, woody fragrance 12g, pinellia 10g, angelica dahurica 20g, roasted licorice 10g.

实施例2 Example 2

一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参20g、焦术40 g、黄芪10g、当归25g、茯神5g、远志20g、炒枣仁20g、龙齿5g、砂仁30g、乌贼骨20g、陈皮5g、木香25g、半夏12g、白芷5g、炙甘草15g。 A traditional Chinese medicine composition for treating insomnia, characterized in that it is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 20g ginseng, 40g jiaozhu, 10g astragalus, 25g angelica, 5g Fushen, 20g polygala, 20g fried jujube kernel , Dragon Tooth 5g, Amomum 30g, Cuttlefish Bone 20g, Tangerine Peel 5g, Woody Fragrance 25g, Pinellia 12g, Angelica dahurica 5g, Zhigancao 15g.

实施例3 Example 3

一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参40g、焦术10 g、黄芪15g、当归10g、茯神30g、远志5g、炒枣仁25g、龙齿10g、砂仁15g、乌贼骨40g、陈皮25g、木香5g、半夏8g、白芷30g、炙甘草5g。 A traditional Chinese medicine composition for treating insomnia, characterized in that: it is composed of the following traditional Chinese medicine raw materials in the following weight ratio: 40g ginseng, 10g jiaozhu, 15g astragalus, 10g angelica, 30g Fushen, 5g polygala, 25g fried jujube kernel , Dragon Tooth 10g, Amomum 15g, Cuttlefish Bone 40g, Tangerine Peel 25g, Woody Fragrance 5g, Pinellia 8g, Angelica dahurica 30g, Zhigancao 5g.

实施例4 Example 4

一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参10g、焦术20g、黄芪40g、当归20g、茯神10g、远志25g、炒枣仁10g、龙齿30g、砂仁5g、乌贼骨10g、陈皮10g、木香15g、半夏5g、白芷10g、炙甘草20g。 A traditional Chinese medicine composition for treating insomnia, characterized in that: it is composed of the following traditional Chinese medicine raw materials in the following weight ratio: 10g ginseng, 20g jiaoshu, 40g astragalus, 20g angelica, 10g Fushen, 25g polygala, 10g fried jujube kernel, Dragon tooth 30g, amomum 5g, cuttlefish bone 10g, tangerine peel 10g, woody fragrance 15g, pinellia 5g, angelica dahurica 10g, licorice 20g.

实施例5 Example 5

一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参25g、焦术15g、黄芪20g、当归5g、茯神15g、远志10g、炒枣仁40g、龙齿15g、砂仁10g、乌贼骨25g、陈皮20g、木香10g、半夏15g、白芷18g、炙甘草12g。 A traditional Chinese medicine composition for treating insomnia, characterized in that: it is composed of the following traditional Chinese medicine raw materials in the following weight ratio: 25g ginseng, 15g jiaozhu, 20g astragalus, 5g angelica, 15g Fushen, 10g polygala, 40g fried jujube kernel, Dragon tooth 15g, amomum 10g, cuttlefish bone 25g, orange peel 20g, woody fragrance 10g, pinellia 15g, angelica dahurica 18g, roasted licorice 12g.

本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约8厘米,进行煎煮。未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二煎煮,水沸后煎煮15~20分钟。两次煎煮取汁,合并。 The traditional Chinese medicine composition in the embodiment of the present invention is prepared according to the conventional water decoction method. The specific method is as follows: put the Chinese medicine raw materials of the prescription into a container, add cold water to cover the surface of the medicine, soak for 15 to 20 minutes, add water to cover the surface of the medicine by about 8 cm, and decoct. Before boiling, use strong fire to decoct, and after boiling, use slow fire to decoct for 20-30 minutes; for the second decoction, decoct for 15-20 minutes after the water boils. Decoct twice to extract the juice and combine.

一种治疗失眠的中药组合物,临床疗效总结: A traditional Chinese medicine composition for treating insomnia, clinical curative effect summary:

一、一般性资料:本中药组合物应用于临床观察病例100例,其中男43例,女57例,年龄20~65岁。 1. General information: This traditional Chinese medicine composition was applied to 100 cases of clinical observation, including 43 males and 57 females, aged 20-65 years.

二、用法用量:临床应用时,组合物中的组分、用量根据患者的体重、年龄及症状酌情增减。一日一剂,水煎两遍取汁约300ml,分早、晚两次服用。 2. Usage and dosage: In clinical application, the components and dosage of the composition can be increased or decreased according to the patient's weight, age and symptoms. One dose a day, decoct in water twice, take about 300ml of juice, and take it twice in the morning and evening.

三、疗效标准: 3. Efficacy standard:

(1)痊愈:症状和体征消失或基本消失; (1) Recovery: symptoms and signs disappear or basically disappear;

(2)显效:症状和体征大部分好转; (2) Significant effect: Most of the symptoms and signs improved;

(3)有效:症状和体征一部分好转; (3) Effective: part of the symptoms and signs improved;

(4)无效;症状和体征均无明显改善,症状如前。 (4) Ineffective; the symptoms and signs were not significantly improved, and the symptoms were as before.

四、治疗效果:该临床观察病例中,服药7-90天,痊愈31例,显效49例,有效16例,无效4例。治疗期间未发生毒副作用。 4. Treatment effect: Among the clinical observation cases, after taking the medicine for 7-90 days, 31 cases were cured, 49 cases were markedly effective, 16 cases were effective, and 4 cases were ineffective. No toxic side effects occurred during the treatment.

五、典型病例: 5. Typical cases:

病例1: Case 1:

时某,男,42岁,公务员,从事文字工作。工作有压力,经常头痛,头昏、头胀,失眠已一年,伴有烦躁,多愁善感,情绪低落,浑身乏力,腰膝酸软,不思饮食等症状。服用本发明的中药组合物制备的药剂1个月,精神情绪状况有所改善;续服1个月,失眠已好。 Shi Mou, male, 42 years old, civil servant, engaged in writing work. Work pressure, frequent headaches, dizziness, dizziness, insomnia for a year, accompanied by irritability, sentimentality, depression, general fatigue, sore waist and knees, not thinking about eating and other symptoms. After taking the medicament prepared by the traditional Chinese medicine composition of the present invention for 1 month, the mental and emotional conditions are improved; after taking it for 1 month, the insomnia is cured.

病例2: Case 2:

周某,女,50岁。就诊自诉:每晚睡眠少于5小时,且5小时内睡眠不深,夜里2-3点醒来不易入睡,呈朦胧状态的时间较多,白天头晕乏力,有半年多。检查:其舌淡苔薄白, 脉象细弦。服用本发明的中药组合物制备的药剂14天,睡眠之中不再醒来,质量明显好转,但难入睡;续服14天,每晚6-7小时睡眠,质量很好;巩固服用7天,痊愈。 Zhou, female, 50 years old. Self-report at the doctor: sleep less than 5 hours every night, and sleep within 5 hours is not deep, wake up at 2-3 o'clock in the night, it is difficult to fall asleep, more time in a hazy state, dizzy and weak during the day, for more than half a year. Inspection: its pale tongue with thin white fur, thready and stringy pulse condition. Take the medicament prepared by the traditional Chinese medicine composition of the present invention for 14 days, no longer wake up in sleep, the quality is obviously better, but it is difficult to fall asleep; continue to take it for 14 days, sleep for 6-7 hours every night, the quality is very good; take it for 7 days ,get well.

病例3: Case 3:

尹某,女,42岁。家人故去,哀思过度后出现头昏头沉、精力不能集中、入睡困难易醒、醒后不能再睡、心烦易怒、胸闷气短、眼颤手颤、胃胀发凉、大便不成型等症状。服用本发明的中药组合物制备的药剂1个月,病情痊愈,随访至今未复发。  Yin, female, 42 years old. After the death of a family member, after excessive mourning, dizziness, inability to concentrate, difficulty falling asleep and waking up easily, restlessness after waking up, upset and irritability, chest tightness, shortness of breath, trembling eyes and hands, stomach distension and coldness, and stools are not formed. Symptoms. Take the medicament prepared by the Chinese medicine composition of the present invention for 1 month, the state of an illness recovers from illness, follow up a case by regular visits to and do not recur so far. the

Claims (2)

1.一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参10~40g、焦白术10~40g、黄芪10~40g、当归5~25g、茯神5~30g、远志5~25g、炒枣仁10~40g、龙齿5~30g、砂仁5~30g、乌贼骨10~40g、陈皮5~25g、木香5~25g、半夏5~15g、白芷5~30g、炙甘草5~20g。 1. A Chinese medicine composition for the treatment of insomnia, characterized in that: it is made up of the following weight ratio of Chinese medicine raw materials: Ginseng 10~40g, Jiaobaizhu 10~40g, Astragalus 10~40g, Angelica 5~25g, Fushen 5-30g, polygala 5-25g, fried jujube kernel 10-40g, dragon tooth 5-30g, amomum 5-30g, cuttlefish bone 10-40g, tangerine peel 5-25g, woody fragrance 5-25g, pinellia 5-15g , Angelica dahurica 5-30g, roasted licorice 5-20g. 2.根据权利要求1所述的一种治疗失眠的中药组合物,其特征在于:其是由下列重量配比的中药原料组成:人参30g、焦白术30 g、黄芪30g、当归15g、茯神20g、远志15g、炒枣仁30g、龙齿20g、砂仁20g、乌贼骨30g、陈皮15g、木香12g、半夏10g、白芷20g、炙甘草10g。 2. a kind of Chinese medicine composition for the treatment of insomnia according to claim 1, is characterized in that: it is made up of the Chinese medicine raw material of following weight ratio: Radix Ginseng 30g, Jiaobaizhu 30g, Radix Astragali 30g, Angelica 15g, Fushen 20g, polygala 15g, fried jujube kernel 30g, dragon tooth 20g, amomum 20g, cuttlefish bone 30g, tangerine peel 15g, woody fragrance 12g, pinellia 10g, angelica dahurica 20g, roasted licorice 10g.
CN2011103341574A 2011-10-29 2011-10-29 Traditional Chinese medicine composition for curing insomnia Pending CN102357225A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142880A (en) * 2013-04-01 2013-06-12 孙福玲 Traditional Chinese medicine composition for insomnia and dreamful sleep caused by acute stress disorder and preparation method of traditional Chinese medicine composition
CN104784664A (en) * 2015-04-23 2015-07-22 樊健 Oral liquid for reducing blood pressure and refreshing

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘学文: "《心悸失眠类方纵横二》", 《中医药学刊》 *
李童: "《归脾汤方证相应研究的文献统计分析》", 《中医学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142880A (en) * 2013-04-01 2013-06-12 孙福玲 Traditional Chinese medicine composition for insomnia and dreamful sleep caused by acute stress disorder and preparation method of traditional Chinese medicine composition
CN104784664A (en) * 2015-04-23 2015-07-22 樊健 Oral liquid for reducing blood pressure and refreshing

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Application publication date: 20120222