CN102319375B - Medicine for treating cervical spondylopathy and preparation method thereof - Google Patents

Medicine for treating cervical spondylopathy and preparation method thereof Download PDF

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CN102319375B
CN102319375B CN 201110232494 CN201110232494A CN102319375B CN 102319375 B CN102319375 B CN 102319375B CN 201110232494 CN201110232494 CN 201110232494 CN 201110232494 A CN201110232494 A CN 201110232494A CN 102319375 B CN102319375 B CN 102319375B
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CN102319375A (en
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俞洋
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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Abstract

The invention discloses a medicine for treating cervical spondylopathy and a preparation method thereof. The medicine comprises the following bulk drugs: 8-10g of pseudostellaria root, 5-10g of hemlock parsley, 15-30g of kudzu root, 8-10g of radix clematidis, 15-20g of white peony root, 15-30g of coix seed, 6-10g of rhizoma corydalis, 10-15g of wolfberry, 15-30g of processed radix aconite, 5-10g of notopterygium root, 8-10g of gastrodia elata, 18-30g of spatholobus stem and 8-10g of mulberry leaf. The preparation method comprises the following steps: decocting the bulk drugs twice, taking the medicinal liquid which is decocted twice out; and combining the twice medicinal liquids to obtain the medicine. The medicine of the invention has the advantages of high curative rate and wide application which is suitable for patients suffering different types of vertebral-artery-type cervical spondylopathy in different degrees; has short treatment course and obvious effect, can take effect in one week and basically relieve clinical symptoms in four weeks; has low price without toxicity or side effect, is convenient to prepare and take, and is suitable for promotion and usage.

Description

A kind of medicine for the treatment of cervical spondylosis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of medicine for the treatment of vertebral artery type of cervical spondylosis and preparation method thereof.
Background technology
Cervical spondylosis is many, and age-dependent, sickness rate are with age growth by due to cervical spine degeneration, and the state of an illness increases the weight of gradually.But in recent years, the sickness rate of teenager cervical spondylosis rises gradually.At present cervical spondylosis has Drug therapy, naturopathy and an operative treatment, and above Therapeutic Method defective: Chinese medicine preparation is innumerable and disordered, and its actual efficacy is low; Though the naturopathy such as massage, acupuncture energy relief of symptoms can not effect a permanent cure by comprehensively regulating, patient's symptom is often delayed time and is sent out; Though operative treatment can be removed the factors such as nerve compression, but many complication such as nerve injury, adhesion, spinal column unstability are arranged also, many patients can not relief of symptoms, and the cervical operation risk is high, difficulty is high, in case occur unexpected, its complication has spinal cord injury, esophageal injury, recurrent nerve injury, vertebral artery injuries, visual area massive hemorrhage, cervical vertebra shakiness, dura mater damage and hematoma etc., even paralysis and dead, more carry out sexually transmitted disease (STD) reason process because cervical spondylosis is, so operative treatment is not that each patient is fit to.
Summary of the invention
Goal of the invention: the first purpose of the present invention is in order to overcome the deficiencies in the prior art, provides that a kind of short treating period, instant effect, cure rate are high, cheap, the medicine of the treatment cervical spondylosis that has no side effect, the especially applicable treatment vertebral artery type of cervical spondylosis of this medicine.
The second purpose of the present invention is for a kind of preparation method for the treatment of the medicine of cervical spondylosis is provided.
Technical scheme: in order to solve above-mentioned the first purpose, the technical solution adopted in the present invention is: a kind of medicine for the treatment of cervical spondylosis, it is mainly made by following bulk drugs: Radix Pseudostellariae 8~10g, Rhizoma Chuanxiong 5~10g, Radix Puerariae 15~30g, Radix Clematidis 8~10g, the Radix Paeoniae Alba 15~20g, Semen Coicis 15~30g, Rhizoma Corydalis 6~10g, Fructus Lycii 10~15g, Radix Polygoni Multiflori Preparata 15~30g, Rhizoma Et Radix Notopterygii 5~10g, Rhizoma Gastrodiae 8~10g, Caulis Spatholobi 18~30g, Folium Mori 8~10g.
Preferably, the consumption of described each crude drug is: Radix Pseudostellariae 10g, Rhizoma Chuanxiong 10g, Radix Puerariae 30g, Radix Clematidis 8g, Radix Paeoniae Alba 15g, Semen Coicis 20g, Rhizoma Corydalis 10g, Fructus Lycii 10g, Radix Polygoni Multiflori Preparata 30g, Rhizoma Et Radix Notopterygii 10g, Rhizoma Gastrodiae 10g, Caulis Spatholobi 30g, Folium Mori 10g.
In order to solve above-mentioned the second purpose, the technical solution adopted in the present invention is: a kind of preparation method for the treatment of the medicine of cervical spondylosis, the method comprises the steps:
(1) take each crude drug according to consumption;
(2) head is fried in shallow oil operation: all crude drug in step (1) are soaked, and the described water yield is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 30 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue that obtains in step (2) is soaked, and this moment, the water yield was 1 times of all crude drug gross weights, and decocting time 15 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil with two the medicinal liquid that obtains in operation and fry in shallow oil with head the medicine that namely gets described treatment cervical spondylosis after the medicinal liquid that obtains in operation mixes.
Beneficial effect: compared with prior art, advantage of the present invention is:
1) cure rate is high, and is applied widely, is applicable to all kinds vertebral artery type of cervical spondylosis Disease in various degree;
2) short treating period, instant effect is generally taken and can be taken effect in a week, takes surrounding and substantially alleviates clinical symptoms;
3) said composition is pure medicine, and is cheap, has no side effect, and preparation, taking convenience are suitable for promoting the use of;
4) formula is simple, and is easy to use.
The specific embodiment
The present invention is further described below by specific embodiment; should be pointed out that for the person of ordinary skill of the art, under the prerequisite that does not break away from the principle of the invention; can also make some modification and improvement, these also should be considered as belonging to protection scope of the present invention.
Embodiment 1: a kind of medicine for the treatment of cervical spondylosis of the present invention comprises that the consumption of following crude drug and each crude drug is respectively: Radix Pseudostellariae 10g, Rhizoma Chuanxiong 10g, Radix Puerariae 30g, Radix Clematidis 8g, Radix Paeoniae Alba 15g, Semen Coicis 20g, Rhizoma Corydalis 10g, Fructus Lycii 10g, Radix Polygoni Multiflori Preparata 30g, Rhizoma Et Radix Notopterygii 10g, Rhizoma Gastrodiae 10g, Caulis Spatholobi 30g, Folium Mori 10g.
The preparation method of this medicine is as follows:
(1) consumption according to each crude drug takes each crude drug;
(2) above-mentioned all crude drug are soaked, amount of water is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 30 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: above-mentioned filtering residue is soaked, and this moment, amount of water was 1 times of all crude drug gross weights, and decocting time 15 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil with two the medicinal liquid that obtains in operation and fry in shallow oil with head the medicine that namely gets described treatment cervical spondylosis after the medicinal liquid that obtains in operation mixes.
Instructions of taking: mixed medicinal liquid is divided take for 2 times on the one.
Embodiment 2: substantially the same manner as Example 1, difference is that the consumption of described each crude drug is: Radix Pseudostellariae 8g, Rhizoma Chuanxiong 8g, Radix Puerariae 15g, Radix Clematidis 8g, Radix Paeoniae Alba 15g, Semen Coicis 15g, Rhizoma Corydalis 6g, Fructus Lycii 10g, Radix Polygoni Multiflori Preparata 15g, Rhizoma Et Radix Notopterygii 5g, Rhizoma Gastrodiae 8g, Caulis Spatholobi 18g, Folium Mori 8g.
Embodiment 3: substantially the same manner as Example 1, difference is that the consumption of described each crude drug is: Radix Pseudostellariae 10g, Rhizoma Chuanxiong 5g, Radix Puerariae 20g, Radix Clematidis 10g, Radix Paeoniae Alba 20g, Semen Coicis 15g, Rhizoma Corydalis 8g, Fructus Lycii 15g, Radix Polygoni Multiflori Preparata 20g, Rhizoma Et Radix Notopterygii 8g, Rhizoma Gastrodiae 9g, Caulis Spatholobi 25g, Folium Mori 10g.
Below further set forth the beneficial effect of Chinese medicine of the present invention by clinical case.
The routine vertebral artery type of cervical spondylosis case of clinical observation 40 with test group treatment vertebral artery type of cervical spondylosis 20 examples, compares with matched group 20 examples.Test group: the medicine described in embodiment 1 in the present invention, be decocted in water for oral dose, every day potion, sooner or later sub-service.Taking medicine continuously 7 days is 1 course for the treatment of, and further consultation in every 7 days once.Be 4 courses for the treatment of observing time.Matched group: adopt the conventional method treatment, 7 days is 1 course for the treatment of, and further consultation in every 7 days once.Be 4 courses for the treatment of observing time.
Efficacy evaluation (with reference to " new Chinese medicine guideline of clinical investigations ")
Clinical recovery: tcm clinical practice symptom, sign disappear or basic the disappearance, and symptom integral reduces 〉=95%.
Produce effects: tcm clinical practice symptom, sign are obviously improved, and symptom integral reduces 〉=70%.
Effectively: tcm clinical practice symptom, sign all take a favorable turn, and symptom integral reduces 〉=30%.
Invalid: all without obviously improving, even increase the weight of, symptom integral reduces less than 30% for tcm clinical practice symptom, sign.
Test group and matched group curative effect relatively see Table 1.
Table 1 test group and matched group curative effect are relatively
Figure BDA0000083235230000031
Test group treatment vertebral artery type of cervical spondylosis 20 examples, total effective rate reaches 95%, with the routine total effective rate 65% of matched group 20, compares, and greatly is better than matched group.Illustrate that Drug therapy vertebral artery type of cervical spondylosis of the present invention is evident in efficacy, have good promotional value.

Claims (3)

1. medicine for the treatment of cervical spondylosis, it is characterized in that, it is to be made by following bulk drugs: Radix Pseudostellariae 8~10g, Rhizoma Chuanxiong 5~10g, Radix Puerariae 15~30g, Radix Clematidis 8~10g, the Radix Paeoniae Alba 15~20g, Semen Coicis 15~30g, Rhizoma Corydalis 6~10g, Fructus Lycii 10~15g, Radix Polygoni Multiflori Preparata 15~30g, Rhizoma Et Radix Notopterygii 5~10g, Rhizoma Gastrodiae 8~10g, Caulis Spatholobi 18~30g, Folium Mori 8~10g; The preparation method of the medicine of described treatment cervical spondylosis comprises the steps:
(1) take each crude drug according to consumption;
(2) head is fried in shallow oil operation: all crude drug in step (1) are soaked, and the described water yield is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 30 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue that obtains in step (2) is soaked, and this moment, the water yield was 1 times of all crude drug gross weights, and decocting time 15 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil with two the medicinal liquid that obtains in operation and fry in shallow oil with head the medicine that namely gets described treatment cervical spondylosis after the medicinal liquid that obtains in operation mixes.
2. a kind of medicine for the treatment of cervical spondylosis according to claim 1, it is characterized in that, the consumption of described each crude drug is: Radix Pseudostellariae 10g, Rhizoma Chuanxiong 10g, Radix Puerariae 30g, Radix Clematidis 8g, Radix Paeoniae Alba 15g, Semen Coicis 20g, Rhizoma Corydalis 10g, Fructus Lycii 10g, Radix Polygoni Multiflori Preparata 30g, Rhizoma Et Radix Notopterygii 10g, Rhizoma Gastrodiae 10g, Caulis Spatholobi 30g, Folium Mori 10g.
3. a kind of preparation method for the treatment of the medicine of cervical spondylosis according to claim 1 and 2, is characterized in that, the method comprises the steps:
(1) take each crude drug according to consumption;
(2) head is fried in shallow oil operation: all crude drug in step (1) are soaked, and the described water yield is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 30 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue that obtains in step (2) is soaked, and this moment, the water yield was 1 times of all crude drug gross weights, and decocting time 15 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil with two the medicinal liquid that obtains in operation and fry in shallow oil with head the medicine that namely gets described treatment cervical spondylosis after the medicinal liquid that obtains in operation mixes.
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CN103083629B (en) * 2011-11-01 2014-01-01 焦国荣 Medicine composition for treating cervical vertebra hyperostosis and preparation method thereof
CN104524454A (en) * 2014-12-22 2015-04-22 况喜才 Tinospora sinensis pain-relieving tincture

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1483446A (en) * 2003-07-30 2004-03-24 童玉新 Traditional Chinese medicine for treating neurosism, extracting process, formation process and use thereof
CN101129973A (en) * 2006-08-25 2008-02-27 范广友 Traditional Chinese medicine for treating cervical vertebra disease
CN101129893A (en) * 2007-08-27 2008-02-27 尹克华 Traditional Chinese medicine for treating cervical vertebra disease combined with diarrhea

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1483446A (en) * 2003-07-30 2004-03-24 童玉新 Traditional Chinese medicine for treating neurosism, extracting process, formation process and use thereof
CN101129973A (en) * 2006-08-25 2008-02-27 范广友 Traditional Chinese medicine for treating cervical vertebra disease
CN101129893A (en) * 2007-08-27 2008-02-27 尹克华 Traditional Chinese medicine for treating cervical vertebra disease combined with diarrhea

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武计香.桂枝加葛根汤治疗颈椎病.《山西中医》.2011,第27卷(第7期),50.
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