CN102309726B - Traditional Chinese medicine composition for treating sick sinus syndrome - Google Patents
Traditional Chinese medicine composition for treating sick sinus syndrome Download PDFInfo
- Publication number
- CN102309726B CN102309726B CN2011102777444A CN201110277744A CN102309726B CN 102309726 B CN102309726 B CN 102309726B CN 2011102777444 A CN2011102777444 A CN 2011102777444A CN 201110277744 A CN201110277744 A CN 201110277744A CN 102309726 B CN102309726 B CN 102309726B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- fructus
- chinese medicine
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 25
- 206010040639 Sick sinus syndrome Diseases 0.000 title claims abstract description 14
- 239000000203 mixture Substances 0.000 title claims abstract description 14
- 241000756943 Codonopsis Species 0.000 claims abstract description 11
- 239000009636 Huang Qi Substances 0.000 claims abstract description 10
- 241000209020 Cornus Species 0.000 claims description 10
- 241000237636 Pheretima Species 0.000 claims description 10
- 241001550206 Colla Species 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 3
- 235000014375 Curcuma Nutrition 0.000 claims description 2
- 244000164439 Curcuma angustifolia Species 0.000 claims description 2
- 241001530126 Scrophularia Species 0.000 claims description 2
- 241000173529 Aconitum napellus Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 241000759833 Cornus officinalis Species 0.000 abstract 1
- 241000893536 Epimedium Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 241000830535 Ligustrum lucidum Species 0.000 abstract 1
- 241000243684 Lumbricus Species 0.000 abstract 1
- 244000241838 Lycium barbarum Species 0.000 abstract 1
- 235000015459 Lycium barbarum Nutrition 0.000 abstract 1
- 235000015468 Lycium chinense Nutrition 0.000 abstract 1
- 240000002948 Ophiopogon intermedius Species 0.000 abstract 1
- 244000226566 Psoralea corylifolia Species 0.000 abstract 1
- 235000003373 curcuma longa Nutrition 0.000 abstract 1
- 239000001215 curcuma longa l. root Substances 0.000 abstract 1
- 235000018905 epimedium Nutrition 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 210000002216 heart Anatomy 0.000 description 19
- 210000003734 kidney Anatomy 0.000 description 19
- 230000007812 deficiency Effects 0.000 description 13
- 210000004185 liver Anatomy 0.000 description 12
- 239000008280 blood Substances 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 11
- 208000002173 dizziness Diseases 0.000 description 11
- 210000004072 lung Anatomy 0.000 description 11
- 235000009508 confectionery Nutrition 0.000 description 10
- 210000000952 spleen Anatomy 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 208000002193 Pain Diseases 0.000 description 7
- 230000001737 promoting effect Effects 0.000 description 7
- 210000001013 sinoatrial node Anatomy 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 208000011580 syndromic disease Diseases 0.000 description 5
- 208000009205 Tinnitus Diseases 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 231100000886 tinnitus Toxicity 0.000 description 4
- 206010010904 Convulsion Diseases 0.000 description 3
- 206010040736 Sinoatrial block Diseases 0.000 description 3
- 206010040741 Sinus bradycardia Diseases 0.000 description 3
- 208000001871 Tachycardia Diseases 0.000 description 3
- 208000006218 bradycardia Diseases 0.000 description 3
- 230000036471 bradycardia Effects 0.000 description 3
- 230000036461 convulsion Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000000232 gallbladder Anatomy 0.000 description 3
- 230000003014 reinforcing effect Effects 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 230000008093 supporting effect Effects 0.000 description 3
- 230000006794 tachycardia Effects 0.000 description 3
- 206010002383 Angina Pectoris Diseases 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 201000004569 Blindness Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 241000201295 Euphrasia Species 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 206010001902 amaurosis Diseases 0.000 description 2
- 206010003549 asthenia Diseases 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 230000001709 ictal effect Effects 0.000 description 2
- 201000001881 impotence Diseases 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 208000013433 lightheadedness Diseases 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 208000008203 tachypnea Diseases 0.000 description 2
- 206010043089 tachypnoea Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010003671 Atrioventricular Block Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 208000031229 Cardiomyopathies Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 208000002330 Congenital Heart Defects Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 208000003430 Mitral Valve Prolapse Diseases 0.000 description 1
- 208000009525 Myocarditis Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241001446509 Psoralea Species 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 241000545442 Radix Species 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 206010040738 Sinus arrest Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000031975 Yang Deficiency Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 210000000593 adipose tissue white Anatomy 0.000 description 1
- 206010002022 amyloidosis Diseases 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 208000028831 congenital heart disease Diseases 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 206010013023 diphtheria Diseases 0.000 description 1
- 208000017574 dry cough Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 230000010247 heart contraction Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 208000015210 hypertensive heart disease Diseases 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 206010029446 nocturia Diseases 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 208000004124 rheumatic heart disease Diseases 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000009978 visual deterioration Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating sick sinus syndrome. The traditional Chinese medicine composition is prepared from radix astragali, honey-fried herba ephedrae, radix codonopsis, cornus officinalis, deerhorn glue, psoralea corylifolia, epimedium, tuber of dwarf lilyturf, radix scrophulariae, ligustrum lucidum, wolfberry, ligusticum wallichii, bitter orange, turmeric root tuber, lumbricus, licorice and monkshood. The traditional Chinese medicine composition can be used in clinic treatment of sick sinus syndrome.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of sick sinus syndrome.
Background technology
Sick sinus syndrome is to cause hypofunction by the sinuatrial node pathological changes, produces multiple ARR general performance.Etiological has coronary heart disease, rheumatic heart disease, congenital heart disease, hypertensive heart disease, myocarditis, cardiomyopathy, mitral valve prolapse, amyloidosis, systemic lupus erythematosus (sle), malnutrition, operation wound, whole body thromboembolism, diphtheria, malignant tumor and idiopathic sinuatrial node sclerosis (degeneration) institute because rising.The symptom of the internal organs blood supply insufficiencies such as the heart relevant with bradycardia, brain appears in the patient, and such as ictal dizzy, amaurosis, weak etc., severe patient can be fainted.If any episode of tachycardia, then the symptoms such as cardiopalmus, angina pectoris can appear.The Sick Sinus Syndrome heart rate can be sometimes fast and sometimes slow, as select all kinds of arrhythmia Western medicine, often attends to one thing and lose sight of another, and is difficult to grasp, and such as pacemaker, then needs certain condition, and some complication may occur.
Summary of the invention
The Chinese medicine composition of the treatment sick sinus syndrome that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt the Radix Astragali, Herba Ephedrae (processed), Radix Codonopsis, Fructus Corni, Colla cornus cervi, Fructus Psoraleae, Herba Epimedii, Radix Ophiopogonis, Radix Scrophulariae, Fructus Ligustri Lucidi, Fructus Lycii, Rhizoma Chuanxiong, Fructus Aurantii, Radix Curcumae, Pheretima, Radix Glycyrrhizae, Radix Aconiti Lateralis Preparata, according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Radix Astragali 20-40 part, Herba Ephedrae (processed) 5-15 part, Radix Codonopsis 5-15 part, Fructus Corni 5-15 part, Colla cornus cervi 10-20 part, Fructus Psoraleae 10-20 part, Herba Epimedii 10-20 part, Radix Ophiopogonis 5-15 part, Radix Scrophulariae 10-20 part, Fructus Ligustri Lucidi 10-20 part, Fructus Lycii 10-20 part, Rhizoma Chuanxiong 5-15 part, Fructus Aurantii 5-15 part, Radix Curcumae 10-20 part, Pheretima 10-30 part, Radix Glycyrrhizae 5-15 part, Radix Aconiti Lateralis Preparata 5-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 30 parts of the Radixs Astragali, 10 parts of Herba Ephedrae (processed), 10 parts of Radix Codonopsis, 10 parts of Fructus Corni, 15 parts of Colla cornus cervis, 15 parts of Fructus Psoraleaes, 15 parts of Herba Epimedii, 10 parts of Radix Ophiopogonis, 15 parts of Radix Scrophulariaes, 15 parts of Fructus Ligustri Lucidi, 15 parts of Fructus Lycii, 10 parts of Rhizoma Chuanxiongs, 10 parts of Fructus Aurantiis, 15 parts of Radix Curcumaes, 20 parts of Pheretimas, 10 parts in Radix Glycyrrhizae, 10 parts of Radix Aconiti Lateralis Preparatas.
The pharmacological action of Chinese medicine of the present invention is as follows:
The Radix Astragali: sweet, warm, return lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.Card for all Qi and blood deficiencies such as diarrhea due to hypofunction of the spleen.
Herba Ephedrae: hot, little hardship, temperature, return lung, urinary bladder channel.Relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema.Be used for chill exterior syndrome.
Radix Codonopsis: sweet, flat.Return spleen, lung meridian.QI invigorating, promote the production of body fluid, nourish blood.The empty asthenia of body that is used for deficiency of QI in middle-JIAO, the cough tachypnea of lung qi virtual loss, breathing hard that hinder in gas Tianjin two is thirsty, dizzy cardiopalmus etc.
Fructus Corni: acid, tepor, return liver, kidney channel.Liver and kidney tonifying, convergence are taken off admittedly.Cure mainly and have a dizzy spell, the cards such as deafness and tinnitus.
Colla cornus cervi: sweet, salty, warm.Return liver, kidney channel.The kidney invigorating and essence nourishing, nourishing blood and preventing abortion, hemostasis.Cure mainly asthenia thin and weak, dizziness and tinnitus, the cards such as soreness of the waist and knees.
Fructus Psoraleae: hot, bitter, warm.Return kidney, spleen channel.Reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, warm spleen antidiarrheal.Be used for the cards such as deficiency and coldness lumbago.
Herba Epimedii: hot, sweet, warm.Return kidney, Liver Channel.Reinforcing the kidney and supporting YANG, strengthening the tendons and bones, expelling wind and removing dampness.Be used for impotence and seminal emission, cold caused by deficiency is sterile, the cards such as cough with asthma of suffering from a deficiency of the kidney.
Radix Ophiopogonis: sweet, little hardship, be slightly cold.Return lung, stomach, heart channel.Nourishing YIN and moistening the lung, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.Cure mainly dryness of the lung dry cough, the deficiency of YIN, Tianjin wound is thirsty, the cards such as vexed insomnia.
Radix Scrophulariae: bitter, sweet, salty, cold, return lung, stomach, kidney channel.Clearing away heat and cooling blood, the YIN nourishing detoxifcation.Be used for the pathogenic warmth cards such as pericardium, maculae caused by violent heat pathogen, laryngopharynx swelling and pain, scrofula sucutaneous nodule of joining the army, cave in.
Fructus Ligustri Lucidi: sweet, bitter, cool.Return liver, kidney channel.Liver and kidney tonifying, clearind deficient heat makes eye bright.Be used for Light-headedness, soreness of the waist and knees, the cards such as tinnitus.
Fructus Lycii: sweet, flat.Return liver, kidney channel.Invigorating the liver and kidney makes eye bright.Be used for deficiency of the liver and kindey, soreness of waist seminal emission is had a dizzy spell, and visual deterioration is quenched one's thirst etc.
Rhizoma Chuanxiong: hot, warm, return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for stagnation of QI and blood, rheumatic arthralgia.
Fructus Aurantii: bitter, acid, be slightly cold.Return lung, spleen, stomach, large intestine channel.The chest stuffiness relieving of regulating the flow of vital energy, the row removing food stagnancy that stagnates.Be used for the chest and diaphragm feeling of fullness, distending pain over the hypochondrium, the cards such as distension and fullness in the abdomen.
Radix Curcumae: bitter, hot, cold, return liver, gallbladder, heart channel.The blood-activating and qi-promoting pain relieving, resolving depression clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood.The card that is used for calentura coma, epilepsy unconsciousness due to blockage of phlegm.
Pheretima: salty, cold.Return lung, liver, kidney channel.Relieving convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and collateral dredging is relievingd asthma.Cure mainly the calentura heating manic, infantile convulsion is twitched, rheumatism hemiplegia, the cards such as cough due to lung-heat.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.The QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine.Be used for abundant expectoration cough, pathopyretic ulcer.
Radix Aconiti Lateralis Preparata: hot, sweet, hot.Poisonous.GUIXIN, kidney, spleen channel.Recuperating depleted YANG and rescuing the patient from collapse, supporing yang benefit fire, dispersing cold for relieving pain.Be used for yang depletion syndrome, the arthralgia due to cold card, the sexual impotence cold womb of deficiency and coldness, abdominal distention is had loose bowels etc.
Motherland's medical science is thought deficiency of heart-QI, and the kidney yang decline is the basic pathogenesis of primary disease.Kidney yang is basis of all sun, and deficiency of heart-YANG and kidney-YANG then directly have influence on the speed of heart beating, and yang deficiency is given birth to endogenous cold, and cold coagulation is stasis then, therefore control with benefiting qi and raising yang blood circulation promoting and blood stasis dispelling.The Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae reinforce functional activities of the heart in the side; Herba Epimedii, Colla cornus cervi, Fructus Psoraleae, Fructus Lycii kidney invigorating and YANG supporting; Herba Ephedrae, Radix Aconiti Lateralis Preparata, Fructus Aurantii have excited sinuatrial node, raising sinuatrial node frequency, improve the function of sinuatrial node surrounding tissue; Rhizoma Chuanxiong, Radix Curcumae, Pheretima blood circulation promoting and blood stasis dispelling improve myocardium dirty function and blood circulation; Radix Ophiopogonis, Radix Scrophulariae, Fructus Corni, Fructus Ligustri Lucidi are made scorching impairment of YIN first, and second the same usefulness of YIN nourishing and warming YANG makes interdependence between yin and yang, then YANG promoting growth while YIN promoting generation.All medicines share benefiting qi and raising yang, blood circulation promoting and blood stasis dispelling, have the obvious function of improving the sinuatrial node heart rate.
Chinese medicine composition of the present invention was in 2008 to 2011 clinical observation sick sinus syndrome 38 routine patients, and clinical report is as follows:
1, physical data
Among the 38 routine patients, women's 15 examples, male's 23 examples, at minimum 26 years old of age, maximum 69 years old, disease time was many at 1-4,40.3 years old mean age.
2, diagnostic criteria
2.1 the symptom of the internal organs blood supply insufficiencies such as the heart relevant with bradycardia, brain appears in the patient, such as ictal dizzy, amaurosis, weak etc., severe patient can be fainted.If any episode of tachycardia, then the symptoms such as cardiopalmus, angina pectoris can appear.
2.2 the electrocardiogram main manifestations comprises: 1. continue and significant sinus bradycardia (50 times/min is following), and cause not due to medicine; 2. sinus arrest and sinoatrial block; 3. sinoatrial block and atrioventricular block exist simultaneously; 4. bradycardia, tachycardia syndrome.
3, Therapeutic Method
3.1 prescription: Radix Astragali 30g, Herba Ephedrae (processed) 10g, Radix Codonopsis 10g, Fructus Corni 10g, Colla cornus cervi 15g, Fructus Psoraleae 15g, Herba Epimedii 15g, Radix Ophiopogonis 10g, Radix Scrophulariae 15g, Fructus Ligustri Lucidi 15g, Fructus Lycii 15g, Rhizoma Chuanxiong 10g, Fructus Aurantii 10g, Radix Curcumae 15g, Pheretima 20g, Radix Glycyrrhizae 10g, Radix Aconiti Lateralis Preparata 10g.
3.2 preparation method: said medicine routinely technique is made decoction.
3.3 instructions of taking: each 1 dose, every day 1 time, 15 days is 1 course for the treatment of.
4, therapeutic outcome:
4.1 criterion of cure
Produce effects: transference cure, average heart rate〉60 times/min, or average sinus rhythm increases〉10 times/min.Take a turn for the better: sx↓, average heart rate increases to some extent, but＜10 times/min.Invalid: symptom does not subtract, and average heart rate is without increase.
4.2 result: among the sick sinus syndrome 38 routine patients, clinical cure (heart rate〉60 times/min, subjective symptoms disappears, the speed syndrome does not occur and faint, sinoatrial block) 20 examples; Effectively (heart rate〉50 times/min, subjective symptoms disappears) 10 examples; Invalid (treat continuously 3 courses for the treatment of, heart rate improves not obvious, and the permanent cardiac pacemaker treatment is installed) 8 examples.
5, model case
5.1 Liu, the woman, 52 years old, December in 2009 7 days was because of the first visit of fainting.The electrocardio diagram: sinus bradycardia, 38 times/min of heart rate, 24h dynamic electrocardiogram diagram: sinus bradycardia and the alternately appearance of overrunning, heart rate is so that type is as main at a slow speed, and the western medicine moon is remaining without obviously improving.Examine and see thready pulse, rule together, 43 times/min, dizziness, cardiopalmus, sensation of oppression over the chest with shortness of breath, light red tongue is thin white.Card belongs to deficiency of heart-YANG, and blood stasis due to qi deficiency is controlled with warming and activating heart-YANG benefiting QI for activating blood circulation.After treating for 1 week, obviously alleviate though heart rate improves not obvious all diseases, continuing takes 2 courses for the treatment of, and heart rate reaches 62 times/min, and all diseases disappear, the check normal ECG, and the 24h ambulatory electrocardiogram is normal.
5.2 the Wang, man, 40 years old.Patient's Light-headedness, dim eyesight tinnitus, the cardiopalmus tachypnea, extremity are not warm, spinal column cold type of pain, nocturia frequency.Once outbreak is fainted three times, each approximate number minute.Purplish tongue is secretly fat, white, slippery and moist fur, and stringy and thready pulse is slow, ties generation.Electrocardiogram shows: hole delays 40 times/min, and card belongs to deficiency of heart-YANG and kidney-YANG, and the blood vessels stasis of blood stagnates.After taking 2 courses for the treatment of, heart rate maintains 55-65 time/min, and remission was followed up a case by regular visits to 3 months, and the faintness symptom does not occur again.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment only is used for explanation the present invention and the present invention is not limited.
Embodiment 1, a kind of Chinese medicine composition for the treatment of sick sinus syndrome, be by Radix Astragali 20g, Herba Ephedrae (processed) 5g, Radix Codonopsis 5g, Fructus Corni 5g, Colla cornus cervi 10g, Fructus Psoraleae 10g, Herba Epimedii 10g, Radix Ophiopogonis 5g, Radix Scrophulariae 10g, Fructus Ligustri Lucidi 10g, Fructus Lycii 10g, Rhizoma Chuanxiong 5g, Fructus Aurantii 5g, Radix Curcumae 10g, Pheretima 10g, Radix Glycyrrhizae 5g, Radix Aconiti Lateralis Preparata 5g make.
Embodiment 2, a kind of Chinese medicine composition for the treatment of sick sinus syndrome, be by Radix Astragali 40g, Herba Ephedrae (processed) 15g, Radix Codonopsis 15g, Fructus Corni 15g, Colla cornus cervi 20g, Fructus Psoraleae 20g, Herba Epimedii 20g, Radix Ophiopogonis 15g, Radix Scrophulariae 20g, Fructus Ligustri Lucidi 20g, Fructus Lycii 20g, Rhizoma Chuanxiong 15g, Fructus Aurantii 15g, Radix Curcumae 20g, Pheretima 30g, Radix Glycyrrhizae 15g, Radix Aconiti Lateralis Preparata 15g make.
Embodiment 3, a kind of Chinese medicine composition for the treatment of sick sinus syndrome, be by Radix Astragali 30g, Herba Ephedrae (processed) 10g, Radix Codonopsis 10g, Fructus Corni 10g, Colla cornus cervi 15g, Fructus Psoraleae 15g, Herba Epimedii 15g, Radix Ophiopogonis 10g, Radix Scrophulariae 15g, Fructus Ligustri Lucidi 15g, Fructus Lycii 15g, Rhizoma Chuanxiong 10g, Fructus Aurantii 10g, Radix Curcumae 15g, Pheretima 20g, Radix Glycyrrhizae 10g, Radix Aconiti Lateralis Preparata 10g make.
Claims (1)
1. Chinese medicine composition for the treatment of sick sinus syndrome is characterized in that it is to be made by following raw material medicaments:
15 parts of 10 parts of Colla cornus cervis of 12 parts of Fructus Corni of 10 parts of Radix Codonopsis of 30 parts of Herba Ephedrae (processed) of the Radix Astragali
15 parts of 15 parts of Fructus Ligustri Lucidi of 15 parts of Herba Epimedii of Fructus Psoraleae, 12 portions of Radix Scrophulariaes, 15 parts of Radix Ophiopogonis
20 parts of 15 parts of Pheretimas of 10 portions of Radix Curcumaes of 10 parts of Fructus Aurantiis of 15 parts of Rhizoma Chuanxiongs of Fructus Lycii
10 parts of 9 parts of Radix Aconiti Lateralis Preparatas of Radix Glycyrrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102777444A CN102309726B (en) | 2011-09-19 | 2011-09-19 | Traditional Chinese medicine composition for treating sick sinus syndrome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102777444A CN102309726B (en) | 2011-09-19 | 2011-09-19 | Traditional Chinese medicine composition for treating sick sinus syndrome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102309726A CN102309726A (en) | 2012-01-11 |
| CN102309726B true CN102309726B (en) | 2013-02-13 |
Family
ID=45423534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102777444A Expired - Fee Related CN102309726B (en) | 2011-09-19 | 2011-09-19 | Traditional Chinese medicine composition for treating sick sinus syndrome |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102309726B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526452A (en) * | 2012-01-19 | 2012-07-04 | 唐山市中医医院 | Traditional Chinese medicine decoction for treating sick sinus syndrome |
| CN102755625B (en) * | 2012-08-08 | 2013-10-30 | 赵玉红 | Traditional Chinese medicine combination for treating myocardial blood deficiency syndrome and preparation method |
| CN102755626B (en) * | 2012-08-08 | 2013-10-09 | 张玉良 | Traditional Chinese medicine combination for treating sinus sick syndrome and preparation method |
| CN104162140A (en) * | 2014-09-10 | 2014-11-26 | 柏伟伟 | Traditional Chinese medicine for treating sick sinus syndrome and preparation method thereof |
| CN104189850A (en) * | 2014-09-22 | 2014-12-10 | 张莉 | Traditional Chinese medicine preparation for treating sick sinus syndrome |
| CN105055846A (en) * | 2015-09-20 | 2015-11-18 | 庞群 | Sick sinus syndrome and drug for treating same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101693099B (en) * | 2009-11-06 | 2011-06-01 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composite for treating tachyrhythmia and its preparation method |
-
2011
- 2011-09-19 CN CN2011102777444A patent/CN102309726B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102309726A (en) | 2012-01-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102309726B (en) | Traditional Chinese medicine composition for treating sick sinus syndrome | |
| CN103705670A (en) | Traditional Chinese medicine for dispelling wind, eliminating dampness and relieving pain and preparation method thereof | |
| CN105561214A (en) | Traditional Chinese medicine composition for treating coronary heart disease | |
| CN104399009A (en) | Traditional Chinese medicine formula for treating liver cancer and preparation method adopting traditional Chinese medicine formula | |
| CN102755626B (en) | Traditional Chinese medicine combination for treating sinus sick syndrome and preparation method | |
| CN103585609B (en) | Traditional Chinese medicine composition for treating dysmenorrhea and preparation method thereof | |
| CN102552753B (en) | Chinese medicinal composition for treating uterine fibroid | |
| CN103083616B (en) | Traditional Chinese medicine for treating ovarian cyst | |
| CN102961561B (en) | Chinese medicinal composition for treating coronary heart disease | |
| CN102579750B (en) | Traditional Chinese medicine composition for treating primary dysmenorrhea | |
| CN102380011B (en) | Traditional Chinese medicine composition for treating polyarteritis nodosa | |
| CN104706870A (en) | Traditional Chinese medicine composition for treating ankylosing spondylitis and preparation method of traditional Chinese medicine composition | |
| CN104189786A (en) | Traditional Chinese medicine for treating rheumatic heart disease | |
| CN103830591A (en) | Traditional Chinese medicine formula for treating stroke and post-traumatic brain syndrome and preparation method of traditional Chinese medicine | |
| CN102949689A (en) | Traditional Chinese medicine preparation for treating spontaneous perspiration and leaking sweat | |
| CN102406797B (en) | Traditional Chinese medicine composition for treating palpitation | |
| CN103110811B (en) | Traditional Chinese medicine composition for treating arrhythmia | |
| CN102755625B (en) | Traditional Chinese medicine combination for treating myocardial blood deficiency syndrome and preparation method | |
| CN102139032A (en) | Traditional Chinese medicine for treating intervertebral disc protrusion, hyperosteogeny and rheumatoid disease | |
| CN102091163B (en) | Chinese medicine composition for treating diabetic heart disease | |
| CN101700340B (en) | Oral traditional Chinese medicine composition for treating chronic nephritis | |
| CN105727163A (en) | A traditional Chinese medicine formula for treating liver cancer and a preparing method thereof | |
| CN104856524B (en) | A kind of antihypertensive health care medicated pillow | |
| CN100548336C (en) | A kind of Chinese medicine composition of orally taken for curing intercostal neuralgia | |
| CN105497823A (en) | Traditional Chinese medicine formula for treating amenorrhea |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: HAIMEN LINJIANG BIO-PARMACEUTICAL TECHNOLOGY AND I Free format text: FORMER OWNER: MA AIFEN Effective date: 20140610 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 262500 WEIFANG, SHANDONG PROVINCE TO: 226133 NANTONG, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20140610 Address after: 226133, Nantong, Jiangsu Province Linjiang New District Linjiang Industrial Park Patentee after: Haimen Linjiang biological medicine science and Technology Pioneer Park Co Ltd Address before: 262500 Shandong province Weifang City Linglong Mountain Road No. 4138 Weifang Yidu Central Hospital Patentee before: Ma Aifen |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130213 Termination date: 20180919 |