CN102293969A - 一种治疗脂肪肝的中药 - Google Patents
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Abstract
本发明公开了一种治疗脂肪肝的中药。它的有效成分是由下述重量份的原料药制成：白芍5-8、石决明8-12、夏枯草6-10、瓦楞子4-6、珍珠母4-6、皂角刺5-8、山楂10-15、茯苓4-6、胆南星4-6、牡丹皮6-10、丹参6-10、三棱5-8、何首乌8-12、桃仁6-10。本发明以天然的中药为原料，各味中药药效间具有协同作用，疗程短，疗效确切，能有效治愈脂肪肝患者。
Description
技术领域
本发明涉及一种治疗脂肪肝的中药，属于中药技术领域。
背景技术
脂肪肝，是指由于各种原因引起的肝细胞内脂肪堆积过多的病变。脂肪性肝病正严重威胁国人的健康，成为仅次于病毒性肝炎的第二大肝病，已被公认为隐蔽性肝硬化的常见原因。脂肪肝的临床表现多样，轻度脂肪肝的症状：有的仅有疲乏感，而多数脂肪肝患者较胖，故更难发现轻微的自觉症状。中重度脂肪肝有类似慢性肝炎的表现，可有食欲不振、疲倦乏力、恶心、呕吐、体重减轻、肝区或右上腹隐痛等。脂肪肝的类型主要有肥胖性脂肪肝、酒精性脂肪肝、营养不良性脂肪肝、糖尿病脂肪肝和其他疾病引起的脂肪肝。
到目前为止，西药尚无防治脂肪肝的有效药物，而中药需要长期调理性的治疗，虽然效果显著，但治疗时间过长，给患者的生活带来一定困扰。
发明内容
为了克服上述现有技术存在的缺点，本发明提供了一种能够治疗脂肪肝的中药，该中药具有疗程短、疗效显著的优点。
本发明的技术方案是：一种治疗脂肪肝的中药，其特征是，其有效成分是由下述重量份的原料药制成：白芍5-8、石决明8-12、夏枯草6-10、瓦楞子4-6、珍珠母4-6、皂角刺5-8、山楂10-15、茯苓4-6、胆南星4-6、牡丹皮6-10、丹参6-10、三棱5-8、何首乌8-12、桃仁6-10。
单剂原料药为(单位：克)：白芍5-8、石决明8-12、夏枯草6-10、瓦楞子4-6、珍珠母4-6、皂角刺5-8、山楂10-15、茯苓4-6、胆南星4-6、牡丹皮6-10、丹参6-10、三棱5-8、何首乌8-12、桃仁6-10。
本发明的进一步技术方案是：一种治疗脂肪肝的中药，其特征是，其有效成分是由下述重量份的原料药制成：白芍6、石决明10、夏枯草8、瓦楞子5、珍珠母5、皂角刺6、山楂12、茯苓5、胆南星5、牡丹皮8、丹参8、三棱6、何首乌10、桃仁8。
制备及服用方法：按上述重量份称取原料药，水煎服，每天1剂，分两次早晚服用。
各味中药的药理作用：
白芍：苦、酸，微寒。归肝、脾经。功能主治：平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
石决明：咸，寒。归肝经。功能主治：平肝潜阳，清肝明目。用于头痛眩晕，目赤翳障，视物昏花，青盲雀目。
夏枯草：辛、苦，寒。归肝、胆经。功能主治：清火，明目，散结，消肿。用于目赤肿痛，目珠夜痛，头痛眩晕，瘰疬，瘿瘤，乳痈肿痛；甲状腺肿大，淋巴结结核，乳腺增生，高血压。
瓦楞子：咸，平。归肺、胃、肝经。功能主治：消痰化瘀，软坚散结，制酸止痛。用于顽痰积结，黏稠难咯，瘿瘤，瘰疬，癥瘕痞块，胃痛泛酸。
珍珠母：咸，寒。归肝、心经。功能主治：平肝潜阳，定惊明目。用于头痛眩晕.烦躁失眠，肝热目赤，肝虚目昏。
皂角刺：辛，温。归肝、胃经。功能主治：消肿托毒，排脓，杀虫。用于痈疽初起或脓成不溃；外治疥癣麻风。
山楂：味酸，性平。归肝经。功能主治：活血化瘀，理气通脉。用于气滞血瘀.胸闷憋气，心悸健忘，眩晕耳鸣。
茯苓：甘、淡，平。归心、肺、脾、肾经。功能主治：利水渗湿，健脾宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
胆南星：苦、微辛，凉。归肺、肝、脾经。功能主治：清热化痰，息风定惊。用于痰热咳嗽，咯痰黄稠，中风痰迷，癫狂惊痫。
牡丹皮：苦、辛，微寒。归心、肝、肾经。功能主治：清热凉血，活血化瘀。用于温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，痈肿疮毒，跌扑伤痛。
丹参：苦，微寒。归心、肝经。功能主治：祛瘀止痛，活血通经，清心除烦。用于月经不调，经闭痛经，癥瘕积聚，胸腹刺痛，热痹疼痛，疮疡肿痛，心烦不眠，肝脾肿大，心绞痛。
三棱：辛、苦，平。归肝、脾经。功能主治：破血行气，消积止痛。用于癥痕痞块，瘀血经闭，食积胀痛。
何首乌：苦、甘、涩.温。归肝、心、肾经。功能主治：解毒，消脱，润肠通便。用于瘰疬疮痈，风疹瘙痒，肠燥便秘，高血脂。
桃仁：苦、甘，平。归心、肝、大肠经。功能主治：活血祛瘀，润肠通便。用于经闭，痛经，癥瘕痞块，跌扑损伤，肠燥便秘。
本发明的有益效果是：本发明以天然的中药为原料，各味中药药效间具有协同作用，疗程短，疗效确切，能有效治愈脂肪肝患者。
临床观察资料：
1.临床资料：选自2009年6月至2010年6月具有完整资料的住院病人共120例。随机分为治疗组60例，对照组60例。治疗组年龄为20-65岁，平均43.6岁，病程1-12年，对照组年龄在19-64岁，平均42.9岁，病程1.5-12.5年，年龄及病程经卡方检验，无统计学显著差异(p＞0.05)。
2.诊断标准：
临床表现无症状，或有疲乏无力、肝区不适、胀满，甚至隐痛、胃纳不佳，颜面痤疮等。B超检查肝脏B型超声波检查，可见脂肪肝图像，即：肝区强回声，肝肾辉区对比下降，肝内脉管硬化，胆囊壁消失。
3.治疗方法：
治疗组服用本发明药物(具体配方见实施例1)，每天1剂，分两次早晚服用，10天为一疗程，对照组用肝得健胶囊，每次2粒，每日2次口服。两组患者均控制饮食，停用其它药物，3个月后统计疗效。
4.疗效评定标准：
治愈：症状消失，血脂、肝功能正常，B超示脂肪肝波型消失，肝脏回缩至正常；
显效：症状基本消失，血脂、肝功能近于正常，B超示脂肪肝波型基本消失，肝脏明显回缩近于正常；
有效：症状大部分消失，血脂、肝功能好转，B超示脂肪肝波型减少，肝脏轻度回缩；
无效：症状及各项检查未见改善。
5.治疗结果：两组治疗结果如表1所示：
表1两组治愈率对照表
经卡方检验，两组有效率比较，差异有非常显著性(P＜0.001)。
典型病例：
病例1：刘某，男，55岁，具有常年喝酒的习惯，自2009年右上腹不适，乏力伴两肋胀痛，经当地医院B超检查诊断为酒精性性脂肪肝，先后在几家医院经中西医治疗1年，效果不佳，自2009年6月开始服用本发明药物，服用2个月后，上述症状全部消失。B超示肝脏恢复正常，一年后随访，病情无复发。
病例2：于某，女，40岁。患者自2006年来身体逐渐肥胖，腹胀，自2009年来右胁隐痛，上腹胀满，肠鸣，便溏，四肢酸困无力。经B超示检查诊断为肥胖性脂肪肝。经朋友介绍服用本发明药物，服用2个月后，上述症状全部消失。B超示肝脏恢复正常，一年后随访，病情无复发。
具体实施方式
实施例1：
配比(单位：克)：白芍6、石决明10、夏枯草8、瓦楞子5、珍珠母5、皂角刺6、山楂12、茯苓5、胆南星5、牡丹皮8、丹参8、三棱6、何首乌10、桃仁8。
制备及服用方法：按上述重量称取原料药，水煎服，每天1剂，分两次早晚服用。
实施例2：
配比(单位：克)：白芍5、石决明8、夏枯草10、瓦楞子4、珍珠母6、皂角刺5、山楂15、茯苓4、胆南星6、牡丹皮10、丹参10、三棱5、何首乌12、桃仁6。
制备方法及服用方法同实施例1。
实施例3：
配比(单位：克)：白芍8、石决明12、夏枯草6、瓦楞子6、珍珠母4、皂角刺8、山楂10、茯苓6、胆南星4、牡丹皮6、丹参6、三棱8、何首乌8、桃仁10。
制备方法及服用方法同实施例1。
Claims (2)
1.一种治疗脂肪肝的中药，其特征是，其有效成分是由下述重量份的原料药制成：白芍5-8、石决明8-12、夏枯草6-10、瓦楞子4-6、珍珠母4-6、皂角刺5-8、山楂10-15、茯苓4-6、胆南星4-6、牡丹皮6-10、丹参6-10、三棱5-8、何首乌8-12、桃仁6-10。
2.根据权利要求1所述的一种治疗脂肪肝的中药，其特征是，其有效成分是由下述重量份的原料药制成：白芍6、石决明10、夏枯草8、瓦楞子5、珍珠母5、皂角刺6、山楂12、茯苓5、胆南星5、牡丹皮8、丹参8、三棱6、何首乌10、桃仁8。
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| CN105497509A (zh) * | 2014-11-07 | 2016-04-20 | 苏珉 | 一种治疗脂肪肝的中药 |
| CN105687615A (zh) * | 2016-04-15 | 2016-06-22 | 魏旭東 | 一种治疗脂肪肝的中药复方 |
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