CN102138800A - Piston type portable detection system for blood of human body - Google Patents

Piston type portable detection system for blood of human body Download PDF

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Publication number
CN102138800A
CN102138800A CN 201010616231 CN201010616231A CN102138800A CN 102138800 A CN102138800 A CN 102138800A CN 201010616231 CN201010616231 CN 201010616231 CN 201010616231 A CN201010616231 A CN 201010616231A CN 102138800 A CN102138800 A CN 102138800A
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blood
piston
detection system
blood sample
capillary
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CN 201010616231
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Chinese (zh)
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CN102138800B (en
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朱正伟
袁侨英
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中国人民解放军第三军医大学第一附属医院
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Abstract

The invention discloses a piston type portable detection system for blood of a human body, which comprises a sensor set, a central processor, a blood sample collection system, a blood sample detection system and a vein retention body. A retention body which can be retained in a vein is adopted; interval time of sampling blood samples is set through the central processor; the blood samples are collected through the blood sample collection system, and are delivered to the blood sample detection system; and the blood sample collection system applied to the clinical can perform painless, controllable and uninterrupted monitoring, blood sample collection and blood sample detection on the blood of the human body; therefore, relatively complete information of the blood of a patient is acquired, and the pathological and physiological states of the human body can be dynamically understood in real time in a whole. In the invention, technical difficulties of influencing subsequent continuous monitoring, wounding the patient and the like due to the blood coagulation and the deposition of substances such as proteins and the like in the blood are avoided; as the blood is sampled from a capillary, the blood sampling quantity is extremely less; the safety range of the health of the human body cannot be damaged; and the portable detection system has a significant meaning for directing clinical treatment.

Description

人体血液活塞式便携检测系统 Piston portable blood detection system

技术领域 FIELD

[0001] 本发明涉及一种医疗器械,特别涉及一种用于对人体血液进行监测、采集和检测的医疗器械。 [0001] The present invention relates to a medical instrument, particularly to a human blood for medical monitoring equipment, collection and detection.

背景技术 Background technique

[0002] 人体血液除含有细胞成分以外,在液态的血浆中,含有蛋白质、非蛋白质含氮物质、脂类、糖,其他有机物(包括维生素、酶、凝血与抗凝血因子等),还有无机物,以适应机体的需要,从人体血液中可得知大量的人体状况信息。 [0002] The blood component in addition to containing cells, the plasma liquid containing the protein, non-protein nitrogenous compounds, lipids, sugars, other organic matter (including vitamins, enzymes, coagulation and anticoagulation factors, etc.), as well as inorganic substances, in order to adapt to the needs of the body, from human blood can know a lot of information about the human condition.

[0003] 现有技术中,需要对血液进行监测和检测时,临床多采用静脉抽血和快速指尖末梢血来检测血样,通过反复针刺采血来实现检测的目的,增加患者的痛苦,并使医务工作者的工作量增加。 When [0003] the prior art, the need for detection and monitoring of blood, venipuncture clinical use and fast fingertip blood sample of peripheral blood is detected, the detected object is achieved by repeating prick, increase the suffering of the patient, and the increase in the workload of health workers. 更重要的是,间隔的单一时间采样,只能反映固定时间点的血液信息(即瞬间血液信息),存在着一定的片面性和不准确性,即使再频繁的指尖或静脉血测量也无法提供M小时连续的血样信息。 More importantly, a single sampling interval, only reflects the blood information (ie information instantly blood) fixed point in time, there is a certain one-sidedness and inaccuracy, even if more frequent fingertip or venous blood measurements can not provide M-hour continuous blood sample information. 瞬间血样信息值也受运动、饮食、药物、情绪波动等诸多因素的影响,无法反映患者全面的"血样信息谱",也很难发现无症状的血液信息异常,例如,较为常见的是高血糖和低血糖。 Blood samples instant information value is also affected by many factors, exercise, diet, medication, mood swings, does not reflect the patient comprehensive "information blood spectrum", it is difficult to find information asymptomatic blood abnormalities, for example, the more common is high blood sugar and low blood sugar. 临床中,体内激素水平的检测也是常用的检测项目,但是,体内许多激素均呈脉冲式分泌,有基础分泌状态,也会因紧张、受刺激等因素而升高,从而引起其浓度在外周血象中的波动,单纯的一次性采血样不能反映体内各种激素的真正水平, 甚至可能造成错误的检验结果,给临床诊断和治疗带来错误的信息。 Clinical detection of hormone levels is also commonly used test items, however, showed many hormones secreted in vivo pulse having a basic secretor status, also because of the tension, and other factors stimulated rises, causing its concentration in the peripheral blood fluctuations in the simple one-time blood samples do not reflect the true level of various hormones in the body, and may even cause erroneous test results, clinical diagnosis and treatment to bring the wrong message. 再有就是,在多数危重急症中,为了解患者的病理信息和指导治疗、评估预后,也需要多次抽血检测,但是很多危急重症患者反复抽取血样会损伤组织和血管,对部分凝血功能异常的患者甚至造成穿刺点出血不止,在病情突然变化加重时,甚至因患者血容量不足、血管塌陷不能成功的采集血样,而每天的抽血量,可能会导致患者在短期内出现贫血。 There is also, in the majority of critical illness, in order to understand the pathological information and guide treatment of patients, assess prognosis, also require multiple blood testing, but many critical patients with severe blood samples were taken repeatedly can damage tissue and blood vessels, on the part of coagulopathy patients and even cause bleeding puncture point, when a sudden change in the condition worsened, even due to lack of patient blood volume, vascular collapse can not be successful blood samples were collected, and the amount of blood a day, may lead to anemia patients in the short term.

[0004] 因此,需要一种能够对人体血液实现动态实时监测和检测的装置,对人体血液进行无痛而又可控不间断的监测、血样采集和血样检测,能够获取患者的血液较为全面的信息,从而从整体实时了解人体的病理生理状态,对指导临床治疗具有较为重要的意义。 [0004] Therefore, a device capable of dynamic real-time monitoring and detection of realization of human blood, human blood is painless but controllable continuous monitoring, blood sampling and blood test, the patient's blood can get more comprehensive information to the overall understanding of the pathophysiology of the real-time status of the human body, has more important implications for clinical treatment.

发明内容 SUMMARY

[0005] 有鉴于此,本发明的目的是提供一种人体血液活塞式便携检测系统,应用于临床, 能够对人体血液进行无痛而又可控不间断的监测、血样采集和血样检测,从而获取患者的血液较为全面的信息,从整体实时了解人体的病理生理状态,对指导临床治疗具有较为重要的意义。 [0005] In view of this, an object of the present invention is to provide a piston type portable blood detection system, used in clinical, human blood can be painless but controllable continuous monitoring, blood sampling and blood testing to the patient's blood get more comprehensive information, from real-time understanding the pathophysiology of the overall state of the body, it has more important implications for clinical treatment.

[0006] 本发明的人体血液活塞式便携检测系统,包括传感器组、中央处理器、血样采集系统、血样检测系统和静脉留置体; [0006] The present invention is human blood piston portable detection system includes a sensor set, a central processor, blood collection system, blood detection system and a venous catheter body;

[0007] 所述传感器组设置于留置体用于采集人体血液流体动力学和气体含量参数并输送至中央处理器储存; [0007] The sensor group provided on the indwelling member for collecting blood gas content and the hydrodynamic parameters of the storage and delivery to the central processor;

[0008] 所述血样检测系统用于接收血样采集系统的血样并进行检测分析并将分析数据传至中央处理器储存; [0008] The blood sample detection system for receiving a blood sample collection and detection system analyzes and analyze the data transmitted to the central processor storage;

[0009] 血样采集系统包括采血活塞、活塞驱动装置、采血毛细管和抽吸装置,所述留置体内设置有前端开口的活塞通道,所述采血活塞穿入活塞通道并与其可往复滑动配合,所述留置体内还设置毛细管通道,所述活塞通道的通道壁靠近前端开有过流通道,所述过流通道与活塞通道前端开口的距离大于采血活塞长度;所述毛细管通道前端通过过流通道连通于活塞通道,所述采血毛细管穿入毛细管通道;所述活塞驱动装置包括驱动电机和齿轮齿条机构,驱动电机的转子与齿轮齿条机构的齿轮传动配合,齿轮齿条机构的齿条固定设置于采血活塞的活塞杆;所述中央处理器的命令输出端连接于驱动电机的控制电路;所述抽吸装置包括缸体、设置于缸体与其往复滑动配合的活塞和用于驱动活塞往复运动的活塞驱动电机,所述缸体设置连通于采血毛细管的进液口 [0009] The blood sample collection system comprising a piston, a piston driving means, and the capillary blood suction device, said catheter body is provided with a front opening of the piston channel, said piston channel penetrating the blood piston reciprocally sliding fit therewith, said vivo indwelling capillary channel is also provided, the channel wall toward the distal end of the piston passageway is opened through the flow path through the flow path from the front end of the piston passage opening is greater than the length of the blood of the piston; the front end of the capillary channel in communication with the flow channel by over- piston channel, penetrating the capillary blood capillary channel; said piston driving means includes a drive motor and a rack and pinion mechanism, with the drive gear, the gear rack and rack mechanism with a rack and pinion mechanism of the rotor is fixed to the motor the blood of the piston rod; said central processor command output is connected to a motor drive control circuit; said suction means comprises a cylinder, a cylinder disposed in a sliding fit therewith reciprocate a piston for driving the piston reciprocates piston driving motor, disposed in communication with the cylinder liquid inlet capillary blood 和连通于血样检测系统的排液口,所述进液口设置进液单向阀,排液口设置排液单向阀。 And a detection system in communication with the blood sample discharge port, the inlet check valve inlet port is provided, the drain discharge port check valve is provided.

[0010] 进一步,还包括壳体,所述留置体位于壳体外部可拆卸式连接于壳体,所述活塞驱动装置、抽吸装置、中央处理器和血样检测系统均设置于壳体内,所述采血毛细管和活塞杆延伸出壳体; [0010] Further, further comprising a housing, said retention member is located outside the housing detachably connected to the housing, said piston drive means, suction means, a central processor and blood detection system are disposed in the housing, the said blood capillaries and the piston rod extending out of the housing;

[0011] 进一步,所述留置体为静脉留置针结构,所述毛细管通道、活塞通道和传感器组的信号输出数据线均设置于静脉留置针的外套管管壁,所述传感器组设置于静脉留置针的外套管管壁前端部; [0011] Further, the indwelling intravenous catheter body is a structure, of the capillary channel, the data signal output lines and the piston channel to a sensor group are arranged intravenous catheter outer pipe wall of the sensor group arranged in venous indwelling the outer wall of the needle distal tube portion;

[0012] 进一步,还包括连接于中央处理器的人机对话界面,所述人机对话界面的键和屏幕设置于壳体; [0012] Further, further comprising a human-machine interface connected to the central processor, the interactive interface keys and screen disposed in the housing;

[0013] 进一步,所述中央处理器设有将信息输出至外部计算机的输出端子; [0013] Further, the central processor is provided with an external computer outputs information to the output terminal;

[0014] 进一步,所述采血毛细管通过软管连通于缸体的进液口; [0014] Further, the blood collection tube by capillary liquid inlet communicating with the cylinder;

[0015] 进一步,所述活塞同轴固定设置丝杆,活塞驱动电机的转子通过齿轮啮合机构传动设置与丝杆配合的螺母;所述缸体内表面设置轴向滑槽,活塞上设置嵌于轴向滑槽的凸起的结构。 [0015] Further, the piston is fixedly arranged coaxially with the screw, rotary piston motor driven by a drive mechanism provided with a gear meshing with a nut screw; said cylinder disposed axially sliding surface provided on the piston fitted in an axial chute raised structures.

[0016] 本发明的有益效果是:本发明的人体血液活塞式便携检测系统,包括传感器组、 中央处理器、血样采集系统、血样检测系统和静脉留置体,采用能够留置于静脉的留置体, 并通过中央处理器设定采血样的间隔时间,由血样采集系统采集血样并输送至血样检测系统,血样采集系统,应用于临床,能够对人体血液进行无痛而又可控不间断的监测、血样采集和血样检测,从而获取患者的血液较为全面的信息,从整体实时动态了解人体的病理生理状态;本发明避免了血液凝固、血液中蛋白等物质沉积影响后续的持续监测、对患者造成创伤等技术难题,而且采血量极少,每次采血量在0. 05ml左右,每天可提供超过300次血样采集,提供详细的检测结果,全部只需要15毫升血液,少于一般普通病人的常规住院采血量少,不会损害人体健康的安全范围,对指导 [0016] Advantageous effects of the present invention are: human blood piston portable detection system of the present invention, includes a sensor set, a central processor, blood collection system, blood detection system and a venous catheter body, can be employed for intravenous indwelling catheter body, and the time interval set by the central processor of the blood samples, blood samples were collected from the blood sample collection and delivery system to the blood detection system, blood collection system, clinical application, painless but can be controlled continuous monitoring of human blood, blood sampling and blood testing to obtain the patient's blood more comprehensive information to understand the pathophysiological condition of the human body from the overall real time dynamic; the present invention avoids the blood coagulation proteins in the blood and other substances deposited affect subsequent continuous monitoring, causing trauma to the patient and other technical problems, and a very small amount of blood per blood volume of about 0. 05ml, available blood collection times per day over 300, detailed detection results, all only 15 ml of blood, than conventional ordinary patients hospitalized blood less, without compromising the safety range of human health, guidance 床治疗具有较为重要的意义。 Bed treatment has more important significance.

附图说明 BRIEF DESCRIPTION

[0017] 下面结合附图和实施例对本发明作进一步描述。 Drawings and embodiments of the present invention will be further described [0017] below in conjunction.

[0018] 图1为本发明的结构示意图; [0018] FIG. 1 is a schematic view of the structure of the present invention;

[0019] 图2为图IA处放大图; [0019] Figure 2 is an enlarged view of the FIG. IA;

[0020] 图3为图1沿BB处剖视图。 [0020] FIG. 3 is a cross-sectional view along BB of FIG. 具体实施方式 Detailed ways

[0021] 图1为本发明的结构示意图,图2为图IA处放大图,图3为图1沿BB处剖视图, 如图所示:本实施例的人体血液活塞式便携检测系统,包括传感器组27、中央处理器17、血样采集系统、血样检测系统和静脉留置体1 ; Schematic structural diagram of [0021] the present invention. FIG. 1, FIG. 2 is an enlarged view of the FIG. IA, FIG. 1 FIG. 3 is a cross-sectional view along the line BB, as shown: the embodiment of the present piston blood portable detection system comprising a sensor group 27, the central processor 17, blood collection system, blood detection system and a venous catheter body;

[0022] 所述传感器组27设置于留置体1用于采集人体血液流体动力学和气体含量参数并输送至中央处理器17储存;储存后的数据经过输出后为医务人员提供诊断依据;所述传感器组27可以包括压力传感器、流速传感器、温度传感器、各项气体传感器等,可以根据病人的状况采用不同的传感器; [0022] The sensor group 27 disposed in the body 1 for collecting the indwelling blood gas content and the hydrodynamic parameters of the central processor 17 and conveyed to the reservoir; data output after storage to provide diagnostic evidence for the medical staff; the the sensor group 27 may include a pressure sensor, flow sensor, temperature sensor, the gas sensor or the like, may be employed in accordance with different sensor status of the patient;

[0023] 所述血样检测系统用于接收血样采集系统的血样并进行检测分析并将分析数据传至中央处理器17储存;储存后的数据经过输出后为医务人员提供诊断依据;血液检测系统10可以采用现有技术的全自动血液检测仪结构,该检测仪包括全自动进样针、分血器、 稀释器、混勻器、定量装置和真空泵,以完成样品的吸取、稀释、传送、混勻,以及将样品移入各种参数的检测区,此外,还设置清洗检测仪管道和排除废液的功能;如图所示,废液排至非也储存罐12 ;使用时,通过中央处理器17事先设定检测的时间间隔,采血后经后续的血液检测仪集成芯片统一检测,实现多种生物信号的采集、检测,比如血糖、血脂等生化指标, 也可以检测细胞因子、血液中激素水平等数值,并输入中央处理器储存。 [0023] The blood sample detection system for receiving a blood sample collection and detection system analyzes and analyze the data transmitted to the central processor 17 is stored; data output after storage to provide diagnostic evidence for the medical personnel; a blood detection system 10 may be employed prior art automatic blood detector structure, the detector including automatic syringe, hematocrit, diluter and mixers, the dosing device and the vacuum pump to complete the suction of the sample, dilution, transfer, mixing uniform, and various parameters into the sample detection zone, in addition, provided the washing liquor was discarded and the detector duct functions; As shown, the waste storage tank 12 is discharged to Definitely; use by the central processor 17 preset detection time interval detected by subsequent uniform blood after blood detector integrated chip, a variety of collecting a biological signal detection, such as blood glucose, lipid biochemical, cytokine may be detected in blood hormone levels other values, and enter the central processor storage.

[0024] 血样采集系统包括采血活塞33、活塞驱动装置、采血毛细管2和抽吸装置,所述留置体1内设置有前端开口的活塞通道34,所述采血活塞33穿入活塞通道34并与其可往复滑动配合,采血活塞33与活塞通道34之间采用无间隙或小间隙滑动配合,避免采血时血液从间隙流出,并在采血结束时以利于活塞通道内的血液排空,为下一次采血做好准备,并保持活塞通道的洁净;所述留置体1内还设置毛细管通道3,所述活塞通道34的通道壁靠近前端开有过流通道4,所述过流通道4与活塞通道34前端开口的距离大于采血活塞33长度,所述毛细管通道3前端通过过流通道4连通于活塞通道34,所述采血毛细管4穿入毛细管通道;能够保证采血活塞33向前时使过流通道与外界和采血毛细管同时连通,空气进入毛细管通道,便于采血;所述活塞驱动装置包括驱动电机7和齿轮齿条机 [0024] Blood collection system 33 comprises a blood, a piston driving means, the capillary blood collection device 2 and the suction piston is provided with a front end opening of the inner passage 34 of the piston body indwelling, piston 33 penetrates into the blood passage 34 and its piston reciprocally sliding fit, without play or use a small blood clearance sliding fit between the piston 33 and the piston passage 34, the gap avoid blood flows from the blood, and blood in order to facilitate the emptying piston channel at the end of blood collection, blood collection for the next prepare and keep clean the piston channel; said indwelling member further disposed inside the capillary channel 13, the piston channel wall 34 near the front end of the channel is opened through the flow passage 4, the flow path through the passage 34 and the piston 4 from the front end opening 33 is greater than the length of the piston blood, the distal end of the capillary channel 3 flow channel 4 via the communication through the piston passage 34, the capillary tube 4 penetrates the blood capillary channel; ensures that the piston 33 forwardly through the blood flow channel and and simultaneously communicating outside blood capillaries, the capillary channel into the air to facilitate blood; the piston drive means includes a drive motor 7 and the rack and pinion unit ,驱动电机7的转子与齿轮齿条机构的齿轮7传动配合,齿轮齿条机构的齿条5固定设置于采血活塞33的活塞杆;所述中央处理器17的命令输出端连接于驱动电机7的控制电路18 ;所述抽吸装置包括缸体21、活塞M和用于驱动活塞M往复运动的活塞驱动电机13,所述活塞M与缸体21往复滑动配合,所述活塞M同轴固定设置丝杆9,活塞驱动电机13的转子传动设置与丝杆9配合的螺母31,如图所示,通过齿轮啮合机构11传动配合,用于驱动活塞M往复运动; 缸体21与活塞M之间沿轴向往复滑动单自由度配合,可采用缸体21内设置轴向滑槽21a 的结构,活塞M上设置嵌于轴向滑槽21a的凸起Ma的结构,以保证螺母31的驱动;所述缸体21设置连通于采血毛细管2的进液口23和连通于血样检测系统的排液口26,所述进液口23设置进液单向阀22,排液口沈设置排液单向阀25 ;如图所示,所述采 , The drive motor rotor and the rack and pinion mechanism 7 with a gear transmission 7, a gear rack and rack 5 fixed to the piston rod 33 of the blood; command output of the central processor 17 is connected to a drive motor 7 the control circuit 18; the suction means comprises a cylinder 21, a piston and a drive piston M M reciprocate the piston drive motor 13, the piston 21 and the cylinder M reciprocally sliding fit, said piston fixed coaxially M set screw 9, the rotor is provided with a drive motor 13 driving lead screw piston 9 with a nut 31, as shown, via a gear meshing with the drive mechanism 11 for driving the piston to reciprocate M; M is the cylinder 21 and the piston between the axially reciprocating slide with one degree of freedom, the chute 21a disposed axially in the cylinder structure 21 can be disposed axially embedded in the structure of the sliding projection 21a of the piston Ma M, to ensure that the drive nut 31 ; the cylinder 21 is provided in communication with the liquid discharge port of the capillary blood inlet 2 and the outlet 23 communicating with the blood sample detection system 26, the inlet port 23 is provided the inlet check valve 22, the discharge port is provided Shen the check valve 25; As shown, the mining 血毛细管2通过软管8连通于缸体21的进液口23,利于保证采血毛细管2的顺畅动作。 Blood capillaries 2 through the hose 8 communicates with the liquid inlet 21 of the cylinder 23, will help ensure smooth operation of the blood capillaries 2.

[0025] 所述中央处理器17的命令输出端连接于驱动电机7的控制电路18和活塞驱动电机13的控制电路14,中央处理器17根据设定的时间和周期控制驱动电机7和活塞驱动电机13的运转,完成自动采血过程;图中虚线为数据信号和命令信号传输原理。 Command output terminal [0025] The central processor 17 is connected to the drive motor control circuit 187 and the control circuit 13 of the piston drive motor 14, the CPU 17 controls the drive motor 7 and the piston drive set period of time and operation of the motor 13, to complete the automatic blood collection procedure; Dash lines and command signals to the data transmission principle. [0026] 本发明在使用时,将静脉留置体1植入静脉,采血毛细管2插入毛细管通道3,利用驱动电机7驱动齿轮齿条机构使采血活塞33回撤吸入血液进入活塞通道34,当采血活塞33退至过流通道4后侧,血液通过过流通道4进入采血毛细管通道3并有采血毛细管2,由抽吸装置送至血样检测系统10 ;采血结束后,采血活塞33在向前运行封住活塞通道34前端开口,抽吸装置继续运行,直至采血毛细管2内的血液全部进入血样检测系统10,血样检测系统10对血样进行检测并得出结果后将结果输入中央处理器17储存并输出;与此同时, 传感器组27采集静脉内的血液流体动力学参数,比如血压、流速等,还有气体含量比如,氧气、二氧化碳等的含量,将采集结果输送至中央处理器储存并输出,达到自动监测、采集和检测的目的。 [0026] The present invention is in use, the implant vein intravenous catheter body 1, 2 is inserted into the capillary blood capillary channel 3, by a driving motor 7 drives the rack and pinion mechanism so that the piston 33 retracement blood intake passage of blood into the piston 34, when the blood the rear piston 33 to retreat through the flow channel 4, through the blood flow channel 4 through the blood into the capillary channel 3 and two capillary blood collection, the blood sample to the detection system 10 by the suction means; after the blood, the piston 33 moves forward in blood after passage of the piston to seal the front end opening 34, a suction device continues to run until the blood in the blood into the whole blood sample capillary tube detection system 10, blood detection system 10 and draw blood samples for the detection result result input and the central processor 17 to store output; At the same time, the fluid acquisition sensor group 27 intravenous hemodynamic parameters, such as the content of blood pressure, flow rate, etc., as well as the gas content, for example, oxygen, carbon dioxide and the like, transporting the collected results to the central processor and the storage output, achieve automatic monitoring, the purpose of the acquisition and detection.

[0027] 本实施例中,还包括壳体30,所述留置体1位于壳体30外部可拆卸式连接于壳体30,长期使用时,可将其进行连接后固定,连接可以采用现有技术的卡接、插接或者螺纹连接等等,如图所示,本实施例中采用插接的方式连接;所述活塞驱动装置、抽吸装置、中央处理器17和血样检测系统10均设置于壳体30内,所述采血毛细管2和采血活塞33的活塞杆延伸出壳体30;本结构简单紧凑,使用方便,可采用较为方便的懈怠和固定结构,便于患者自行使用;壳体可制成较小的体积,可由医疗专业人员为患者随身佩带,患者在日常生活状况下检测并记录血样数据;中央处理器可装入相应的软件,患者还可自行输入"事件" 标记,包括进餐、运动、用药等情况,利于诊断治疗。 [0027] In this embodiment, further includes a housing 30, the retention member 1 is located outside the housing 30 detachably connected to the housing 30, long-term use, it can be fixed after the connection, the connection may be used prior technology snap, screw or plug connection, etc., as shown, in connection with plug embodiment according to the present embodiment; the piston drive means, suction means, a central processor 17 and the detection system 10 are set blood in the housing 30, the lancing of blood capillaries 2 and the piston rod 33 extends out of the housing 30; this configuration is simple and compact, easy to use, and can be more convenient slack fixed structure, easy to use patient self; housing may made smaller volume, the patient may be worn medical professional, patient blood samples detected and recorded in the data about daily life; central processor software may be loaded into the appropriate patient may also enter your own "event" markers including meal situation, exercise, medication, etc., which will help diagnosis and treatment.

[0028] 本实施例中,所述留置体1为静脉留置针结构,所述毛细管通道3、活塞通道34、过气通道4和传感器组27的信号输出数据线观均设置于静脉留置针的外套管管壁,所述传感器组27设置于静脉留置针的外套管管壁前端部,信号输出数据线通过插接口四连于中央处理器17 ;进行血液检测的同时,还可以进行输液等治疗措施,使本发明实现功能多样化。 [0028] In this embodiment, the body 1 indwelling venous catheter structure, of the capillary channel 3, piston channel 34, the data signal output lines 4 and the intake passage through the concept of the sensor group 27 are disposed in the intravenous catheter outer tube wall, said group of sensors 27 provided in the outer sleeve wall of the distal end portion of the intravenous catheter, a signal output through the data line sockets in the central processor 17 tetranectin; simultaneously detecting blood, infusion therapy can also be measures to enable the invention to achieve functional diversity.

[0029] 本实施例中,还包括连接于中央处理器17的人机对话界面16 ;可以将实时采集的数据送至该界面,便于实时监控。 [0029] In this embodiment, further comprising a central processing unit connected to the interactive interface 17, 16; real-time collection of data may be sent to the interface for real-time monitoring.

[0030] 本实施例中,所述中央处理器17设有将信息输出至外部计算机的输出端子32,血样采集和记录结束后,可将储存的数据信息传输至计算机,并显示或者打印,为治疗提供有效地理论依据;通过数据处理,医疗专业人员可以获知患者1〜3天内的血样变化情况,包括采集时间最高和最低血样值、血样超过或低于设定血样值的时间和所占比例、血样变化范围以及任何确定时间的血样值等等,还能绘制出精确的每日血样变化曲线,在曲线上标有运动、饮食、睡眠、服药、情绪变化等事件的标志,即绘制出完整、详细、全面的血样检测图谱。 [0030] In this embodiment, the central processor 17 has a data transmitting output information to the output terminal of the external computer 32, after blood sampling and recording, to the computer may be stored and displayed or printed for provide effective treatment of the theoretical basis; data processing, medical professionals can learn the change of ~ 3 days blood samples of patients, including the collection of blood samples the highest and lowest values ​​of time, blood samples above or below the set time and the proportion of the value of the blood sample blood samples to determine any changes in the scope and time of blood values, etc., can draw blood daily precise curve, there are exercise, diet, sleep curve superscript, mark events of medication, mood changes, that is, draw a complete , detailed and comprehensive blood test patterns. 通过血样图谱,医生可以发现许多常规血样监测方法不能发现的问题,真正认识人体的病理生理过程,从而为临床的及时诊断和合理治疗提供重要的线索。 Map by blood, doctors can find problems in many routine blood monitoring methods can not find a genuine understanding of the pathophysiology of the human body, thus providing important clues for timely diagnosis and appropriate clinical treatment.

[0031] 最后说明的是,以上实施例仅用以说明本发明的技术方案而非限制,尽管参照较佳实施例对本发明进行了详细说明,本领域的普通技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本发明技术方案的宗旨和范围,其均应涵盖在本发明的权利要求范围当中。 [0031] Finally is noted that, the above embodiments are intended to illustrate and not limit the present invention, although the present invention has been described in detail with reference to preferred embodiments, those of ordinary skill in the art should be understood that the present invention technical solution modifications or equivalent replacements without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the present invention as claimed in which the required range.

Claims (7)

1. 一种人体血液活塞式便携检测系统,其特征在于:包括传感器组、中央处理器、血样采集系统、血样检测系统和静脉留置体;所述传感器组设置于留置体用于采集人体血液流体动力学和气体含量参数并输送至中央处理器储存;所述血样检测系统用于接收血样采集系统的血样并进行检测分析并将分析数据传至中央处理器储存;血样采集系统包括采血活塞、活塞驱动装置、采血毛细管和抽吸装置,所述留置体内设置有前端开口的活塞通道,所述采血活塞穿入活塞通道并与其可往复滑动配合,所述留置体内还设置毛细管通道,所述活塞通道的通道壁靠近前端开有过流通道,所述过流通道与活塞通道前端开口的距离大于采血活塞长度;所述毛细管通道前端通过过流通道连通于活塞通道,所述采血毛细管穿入毛细管通道;所述活塞驱动装置包括驱动电机和 A piston-type portable blood detection system, characterized by: a group of sensors, central processing unit, blood collection system, blood detection system and a venous catheter body; said group of sensors disposed in the indwelling human body for collecting blood fluid kinetic parameters of gas content and delivered to the central processor and storage; said blood sample detection system for receiving a blood sample and blood sample collection system detects and analyzes the data transmitted to the central processor to store analysis; blood sample collection system comprising a piston drive means, suction means and the capillary blood collection, the catheter body is provided with a front end opening of the piston channel, said piston channel penetrating the piston and blood reciprocally sliding fit therewith, said catheter body further provided a capillary channel, said piston channel channel wall toward the distal end is opened through the flow path through the flow path from the front end of the piston passage opening is greater than the length of the piston blood; channel distal end of the capillary flow passage communicating through the through passage in the piston, penetrates the blood capillaries of the capillary passage ; said piston driving means includes a drive motor and 轮齿条机构,驱动电机的转子与齿轮齿条机构的齿轮传动配合,齿轮齿条机构的齿条固定设置于采血活塞的活塞杆;所述中央处理器的命令输出端连接于驱动电机的控制电路;所述抽吸装置包括缸体、设置于缸体与其往复滑动配合的活塞和用于驱动活塞往复运动的活塞驱动电机,所述缸体设置连通于采血毛细管的进液口和连通于血样检测系统的排液口,所述进液口设置进液单向阀,排液口设置排液单向阀。 Tooth bar mechanism, with the drive gear, a gear rack and rack mechanism with a rack and pinion mechanism of the rotor of the motor fixed to the blood of the piston rod; command output of said central processor is connected to the control drive motor circuit; the suction means comprises a cylinder, the cylinder disposed on the reciprocating slide fit therewith and a piston for driving the piston reciprocates a piston driving motor, the cylinder is provided in communication with capillary blood inlet and communicating with the blood sample detection system liquid discharge port, the inlet check valve inlet port is provided, the discharge port check valve is provided drain.
2.根据权利要求1所述的人体血液活塞式便携检测系统,其特征在于:还包括壳体,所述留置体位于壳体外部可拆卸式连接于壳体,所述活塞驱动装置、抽吸装置、中央处理器和血样检测系统均设置于壳体内,所述采血毛细管和活塞杆延伸出壳体。 The piston-type portable blood detection system according to claim 1, characterized in that: further comprising a housing, said retention member is located outside the housing detachably connected to the housing, the piston driving means, the suction means the central processor and blood detection system are disposed in the housing, said piston rod extending out of blood capillaries and the housing.
3.根据权利要求2所述的人体血液活塞式便携检测系统,其特征在于:所述留置体为静脉留置针结构,所述毛细管通道、活塞通道和传感器组的信号输出数据线均设置于静脉留置针的外套管管壁,所述传感器组设置于静脉留置针的外套管管壁前端部。 The piston-type portable blood detection system according to claim 2, wherein: said indwelling intravenous catheter body is a structure, the data signal output line of the capillary channel, and the piston channel sensor group are provided in the vein catheter outer tube wall, said group of sensors disposed at the distal end portion of the outer pipe wall of the intravenous catheter.
4.根据权利要求3所述的人体血液活塞式便携检测系统,其特征在于:还包括连接于中央处理器的人机对话界面,所述人机对话界面的键和屏幕设置于壳体。 Piston according to claim blood portable detection system according to claim 3, characterized in that: further comprising a central processor connected to the interactive interface, the interactive interface keys and screen disposed in the housing.
5.根据权利要求4所述的人体血液活塞式便携检测系统,其特征在于:所述中央处理器设有将信息输出至外部计算机的输出端子。 The piston-type portable blood detection system of claim 4, wherein: said central processing unit is provided with an external computer outputs information to the output terminal.
6.根据权利要求5所述的人体血液活塞式便携检测系统,其特征在于:所述采血毛细管通过软管连通于缸体的进液口。 The piston-type portable blood detection system according to claim 5, characterized in that: said blood inlet port communicating through a hose to the capillary cylinder.
7.根据权利要求6所述的人体血液活塞式便携检测系统,其特征在于:所述活塞同轴固定设置丝杆,活塞驱动电机的转子通过齿轮啮合机构传动设置与丝杆配合的螺母;所述缸体内表面设置轴向滑槽,活塞上设置嵌于轴向滑槽的凸起的结构。 The piston-type portable blood detection system according to claim 6, wherein: said piston is disposed coaxially fixed screw, rotary piston motor driven by a drive mechanism provided with a gear meshing with a nut screw; the the inner surface of said axially disposed slide cylinders, disposed axially raised structures embedded in the sliding piston.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104856703A (en) * 2015-05-12 2015-08-26 黄彦召 Rapid blood glucose monitoring needle
CN105411608A (en) * 2011-10-05 2016-03-23 生物梅里埃公司 Assembly For Determining The Presence Or Absence Of An Analyte In A Blood Sample And Analysis Unit Comprising Such An Assembly
CN106405134A (en) * 2016-08-26 2017-02-15 卢明杰 Concealed blood collection device used in blood cell analyzer

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1192351A (en) * 1998-03-26 1998-09-09 王明时 Instrument for quick measuring blood viscosity
EP0992287A2 (en) * 1998-10-08 2000-04-12 GHS Gesundheits-Service AG Device for taking and retaining a material to be analysed
CN1449840A (en) * 2002-02-26 2003-10-22 生命扫描有限公司 System and method for remotely medicine infusion and analyte monitoring
US20080021294A1 (en) * 2006-07-14 2008-01-24 Levin Paul D Disposable blood glucose sensor with internal pump
CN101547633A (en) * 2006-10-04 2009-09-30 戴克斯卡姆公司 Analyte sensor
CN201353361Y (en) * 2009-02-23 2009-12-02 刘春香;韦涌初;祝立阳 Disposable multifunctional vein remaining needle

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1192351A (en) * 1998-03-26 1998-09-09 王明时 Instrument for quick measuring blood viscosity
EP0992287A2 (en) * 1998-10-08 2000-04-12 GHS Gesundheits-Service AG Device for taking and retaining a material to be analysed
CN1449840A (en) * 2002-02-26 2003-10-22 生命扫描有限公司 System and method for remotely medicine infusion and analyte monitoring
US20080021294A1 (en) * 2006-07-14 2008-01-24 Levin Paul D Disposable blood glucose sensor with internal pump
CN101547633A (en) * 2006-10-04 2009-09-30 戴克斯卡姆公司 Analyte sensor
CN201353361Y (en) * 2009-02-23 2009-12-02 刘春香;韦涌初;祝立阳 Disposable multifunctional vein remaining needle

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105411608A (en) * 2011-10-05 2016-03-23 生物梅里埃公司 Assembly For Determining The Presence Or Absence Of An Analyte In A Blood Sample And Analysis Unit Comprising Such An Assembly
CN104856703A (en) * 2015-05-12 2015-08-26 黄彦召 Rapid blood glucose monitoring needle
CN106405134A (en) * 2016-08-26 2017-02-15 卢明杰 Concealed blood collection device used in blood cell analyzer
CN106405134B (en) * 2016-08-26 2018-01-26 山丹县天马科技有限责任公司 A blood cell analyzer

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