CN102085342A - External cassia bark and monkshood powder for neonatal scleredema - Google Patents

Abstract

The invention relates to the field of medical formulas, in particular to external cassia bark and monkshood powder for neonatal scleredema. The cassia bark and monkshood powder is prepared by adopting cassia barks, monkshoods, syzygium aromaticum, radix aconiti agrestis, safflower, nutgrass galingale rhizomes, rhizoma zingiberis, radix bupleuri, officinal magnolia barks, curcuma zedoary, Tuckahoe, pericarpium citri reticulatae viride, rhizoma sparganii, rhizoma atractylodis macrocephalae, gallnuts and angelica sinensis as raw materials through drying and grinding the raw materials into fine powder, sieving through a sieve of 100 meshes and uniformly mixing. The powder is characterized by comprising the following components in percentage by weight: 12-15 percent of cassia bark, 8-12 percent of monkshood, 5-8 percent of syzygium aromaticum, 7-10 percent of radix aconiti agrestis, 4-8 percent of safflower, 4-7 percent of nutgrass galingale rhizome, 3-6 percent of rhizoma zingiberis, 4-7 percent of radix bupleuri, 3-6 percent of officinal magnolia bark, 4-6 percent of curcuma zedoary, 5-7 percent of Tuckahoe, 8-12 percent of pericarpium citri reticulatae viride, 3-6 percent of rhizoma sparganii, 2-5 percent of rhizoma atractylodis macrocephalae, 2-4 percent of gallnut and 2-5 percent of angelica sinensis. The external cassia bark and monkshood powder has the advantages of low cost, high efficiency for treating the neonatal scleredema and no toxic and side effects and is suitable for scleredema caused by some diseases and multiple organ damages due to cold and insufficient heat preservation.

Description

The external Cortex Cinnamomi Radix Aconiti powder that is used for neonatal scleredema

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of external Cortex Cinnamomi Radix Aconiti powder that is used for neonatal scleredema.

Background technology

As everyone knows, neonatal cold injure syndrome is called for short neonatal cold injure syndrome, swollen firmly because of skin is arranged more, so be referred to as neonatal scleredema again.System is because due to cold or the multiple disease, swelling firmly with hypothermia and skin is main clinical manifestation, and serious symptom can concurrent multiple organ dysfunction syndrome.Its main diseases is because cold not enough with insulation, and neonate is the premature infant especially, and it is more that the hard bullate reason of hypothermia and skin easily takes place: some disease, severe infections, anoxia, heart failure and shock etc. hypothermia can occur and skin is swollen firmly.Multiple organ injury causes capillary of skin wall permeability to increase, and edema can occur.Clinical manifestation: morbidity in the week behind the Chang Yusheng, the premature infant sees that hypothermia and skin are swollen firmly to be the primary disease main feature more.Body temperature is lower than 35 degrees centigrade, and skin is swollen firmly, and promptly skin is close to subcutaneous tissue, can not move, and the seemingly rubber-like sense of pressing is kermesinus or livid purple color, and companion edema person has the finger pressure depression.The hard swollen symmetry that often is.Clinical treatment mainly is that attention is warming, supplies with heat and liquid and replenishes and use the antibiotic control infection.Both increased the neonate misery, therapeutic effect is not good yet.As hard swollen enlarged areas, further increasing the weight of of anoxia and metabolic acidosis can cause the multiple organ dysfunction infringement, brought life danger, financial burden and psychic pain for infant, family.

Summary of the invention

Purpose of the present invention provides a kind of external Cortex Cinnamomi Radix Aconiti powder that is used for neonatal scleredema in order to overcome above-mentioned existing technical deficiency, and cost is low, treatment neonatal scleredema curative effect height, have no side effect, be applicable to cold and the insulation deficiency, it is swollen firmly that skin appears in some disease and multiple organ injury.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of external Cortex Cinnamomi Radix Aconiti powder that is used for neonatal scleredema, adopt Cortex Cinnamomi, Radix Aconiti, Flos Caryophylli, Radix Aconiti Kusnezoffii, Flos Carthami, Rhizoma Cyperi, Rhizoma Zingiberis, Radix Bupleuri, Cortex Magnoliae Officinalis, Rhizoma Curcumae, Poria, Pericarpium Citri Reticulatae Viride, rhizoma sparganic, the Rhizoma Atractylodis Macrocephalae, Galla Chinensis, when being classified as raw material, raw material stoving is ground into fine powder, cross 100 mesh sieves, mix homogeneously, promptly make medicated powder, it is characterized in that the raw material composition is by weight percentage: Cortex Cinnamomi 12～15%, Radix Aconiti 8～12%, Flos Caryophylli 5～8%, Radix Aconiti Kusnezoffii 7～10%, Flos Carthami 4～8%, Rhizoma Cyperi 4～7%, Rhizoma Zingiberis 3～6%, Radix Bupleuri 4～7%, Cortex Magnoliae Officinalis 3～6%, Rhizoma Curcumae 4～6%, Poria 5～7%, Pericarpium Citri Reticulatae Viride 8～12%, rhizoma sparganic 3～6%, the Rhizoma Atractylodis Macrocephalae 2～5%, Galla Chinensis 2～4%, Radix Angelicae Sinensis 2～5%.

The invention has the beneficial effects as follows that cost is low, treatment neonatal scleredema curative effect height has no side effect, and is applicable to cold and the insulation deficiency, and it is swollen firmly that skin appears in some disease and multiple organ injury.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1:

Adopt Cortex Cinnamomi, Radix Aconiti, Flos Caryophylli, Radix Aconiti Kusnezoffii, Flos Carthami, Rhizoma Cyperi, Rhizoma Zingiberis, Radix Bupleuri, Cortex Magnoliae Officinalis, Rhizoma Curcumae, Poria, Pericarpium Citri Reticulatae Viride, rhizoma sparganic, the Rhizoma Atractylodis Macrocephalae, Galla Chinensis, form when being classified as feedstock production.Its component (weight %) is Cortex Cinnamomi 13.7, Radix Aconiti 10.3, Flos Caryophylli 6.9, Radix Aconiti Kusnezoffii 8.6, Flos Carthami 5.7, Rhizoma Cyperi 5.7, Rhizoma Zingiberis 5.1, Radix Bupleuri 4.6, Cortex Magnoliae Officinalis 4, Rhizoma Curcumae 4.6, Poria 6.9, Pericarpium Citri Reticulatae Viride 8.6, rhizoma sparganic 5.7, the Rhizoma Atractylodis Macrocephalae 3.4, Galla Chinensis 3.4, Radix Angelicae Sinensis 2.8 for every pair.Getting above-mentioned 16 flavor raw material gross weights is 175 grams, after above-mentioned 16 flavor Chinese herbal medicine oven dry, grinds into fine powder, crosses 100 mesh sieves, stirs, and tightens bag mouth in the freshness protection package of packing into, puts into the tight lid of container inner cap again.According to hard swollen position area, get about aforesaid Cortex Cinnamomi Radix Aconiti powder 60～80 grams, with the cooled vaseline oil furnishing ointment of dissolving, with cotton swab ointment is spread upon hard swollen position uniformly, be coated with the ointment edge outward and surpass hard swollen position 1～2cm, the lid petrolatum oil gauze covers nontoxic preservative film again, fixing with applying ointment or plaster, change dressings every day 1～2 time.The early stage position of neonatal scleredema is few, area is little, and effect is good more, and medication 5th～7 was a course of treatment.

Principal agent Cortex Cinnamomi Oleum Cinnamomi of the present invention has demulcent stimulation to gastrointestinal, can strengthen digestive function, gets rid of pneumatosis in the digestive tract, alleviates crampy gastrointestinal pain.Oleum Cinnamomi has the effect of central and tip blood vessel dilating.Nature and flavor suffering, sweet, big heat are returned kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, let the fire back to its origin, dispersing cold for relieving pain, the function of promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney and do to breathe heavily, sexual impotence is dizzy, the conjunctival congestion pharyngalgia, and trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.Radix Aconiti nature and flavor suffering, hardship, heat, very toxic.GUIXIN, liver,kidney,spleen warp.Have expelling wind and removing dampness, the function of antalgic is used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, and colic of cold type is had a pain, narcotic analgesic.Flos Caryophylli nature and flavor suffering, temperature, return spleen, stomach, lung, kidney channel.Have warming middle-JIAO to send down the adverse QI, the function of reinforcing the kidney and supporting YANG is used for Deficiency and coldness of spleen and stomach, singultus vomiting, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.Radix Aconiti Kusnezoffii nature and flavor suffering, hardship, heat, very toxic, GUIXIN, liver,kidney,spleen warp.Has expelling wind and removing dampness, the function of antalgic.Be used for anemofrigid-damp arthralgia, arthralgia.Colic of cold type is had a pain, narcotic analgesic.Flos Carthami nature and flavor suffering, temperature, GUIXIN, Liver Channel.Has promoting blood circulation to remove obstruction in the collateral, the function of eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, the not all right ， mass in the abdomen of lochia mass in the abdomen, traumatic injury, skin infection swells and ache.Rhizoma Cyperi nature and flavor suffering, little hardship, little sweet, put down, return liver, spleen, tri-jiao channel.Have promoting QI circulation for relieving depression, the function of menstruction regulating and pain relieving is used for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, and dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache etc.Rhizoma Zingiberis nature and flavor suffering, heat, return spleen, stomach, kidney, the heart, lung meridian.Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the function of dampness expectorant.Be used for coldness and pain in the epigastrium, vomit and have loose bowels, the cold extremities faint pulse, phlegm retention is breathed with cough.Radix Bupleuri nature and flavor hardship, be slightly cold, return liver, gallbladder meridian.Function with reconciling superficies and interior, soothing the liver, yang invigorating.Be used for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia etc.Cortex Magnoliae Officinalis, nature and flavor hardship, suffering, temperature are returned spleen, stomach, lung, large intestine channel.Have dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards except that full function.Be used for the humidity hysteresis damaging the spleen and stomach, the gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, and abdominal distention constipation, phlegm retention is breathed with cough.Rhizoma Curcumae nature and flavor suffering, hardship, temperature are returned liver, spleen channel.Has the circulation of qi promoting removing blood stasis, removing food stagnancy analgesic function.Yong Yu mass in the abdomen mass in the abdomen, congestion amenorrhea, food stagnation distending pain.The Poria nature and flavor are sweet, light, flat, GUIXIN, lung, spleen, kidney channel.Has promoting diuresis to eliminate damp pathogen, the function of spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool.Pericarpium Citri Reticulatae Viride nature and flavor hardship, suffering, temperature are returned liver, gallbladder, stomach warp.Has soothing the liver dispelling the stagnated QI, the function that removing food stagnancyization stagnates.Be used for distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.Rhizoma sparganic nature and flavor suffering, hardship, equal, return liver, spleen channel.Has the removing blood stasis circulation of qi promoting, removing food stagnancy analgesic function.Yong Yu mass in the abdomen mass in the abdomen, congestion amenorrhea, food stagnation distending pain.Rhizoma Atractylodis Macrocephalae nature and flavor hardship, sweet, warm is returned spleen, stomach warp.Have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive function are used for insufficiency of the spleen lack of appetite, and abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Lung, large intestine, kidney channel are returned in Galla Chinensis nature and flavor acid, puckery, cold.Have the pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, the arresting sweating hemostasis, removing dampness is held back the function of skin ulcer, is used for carbuncle sore tumefacting virus.The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm, return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, and the function of loosening bowel to relieve constipation is used for blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, ulcer sores.Cortex Cinnamomi Radix Aconiti powder prescription is ingenious, between medicine effect mutually suitable, the identical or approximate compatibility of drugs of drug effect function, medicament curative effect enhancement; Effect influence mutually improves main curative effect between medicine; Act on mutual restraint between two drugs between medicine, its toxic and side effects is alleviated or disappear.The Qing Dynasty cures tame Wu Shangxian and says: " just sick curing the disease, skin every and the hair key is logical, lose internal organs and just reach internal organs also." children's's fragile muscle and skin is thin, medicine from outside embrocate, the efficacy of a drug sick institute that can go directly has regulating yin and yang, promoting blood circulation to restore menstrual flow, benefit is fiery supporing yang, the effect of let the fire back to its origin.Traditional Chinese medical science external used medicine Transdermal absorption studies show that Chinese medicine directly acts on body surface, can percutaneous permeability, and the body fluid, blood circulation, the organ that directly enter inside of human body are had an effect.Be not subjected to the influence of pipe intestinal digesting liquid, digestive enzyme, pH value, effect is rapid, curative effect is reliable.Cortex Cinnamomi is the bark of Lignum cinnamomi camphorae plant, and fragrance is strong, experimental results show that the good short effect of oozing with mouse skin.Flos Caryophylli is the medicine flower bud of plant clove of myrtaceae tree, and Flos Caryophylli is short oozing the function except contained composition has, and still contains some other composition, have pain relieving, warming the interior, the function of cold expelling has the short dual-use function that oozes, treats, and is expected to become up-and-coming novel penetrating agent with Chinese traditional treatment effect.Cortex Cinnamomi Radix Aconiti powder has specially good effect to neonatal scleredema.

But each raw material of the present invention also blended embodiment of the listed ratio of according to the form below (percentage by weight) is realized.Its processing technique is identical with embodiment 1.

Below in conjunction with my institute, i.e. the clinical trial carried out of Shandong Province Wendeng Central Hospital, Weihai City is done further, detailed description to the present invention

1, case is selected: this organizes 30 examples, the age: birth back 2～8 days, 2 days 6 examples wherein, 3～5 days 16 examples, 6～8 days 8 examples.

2, Therapeutic Method: above-mentioned 16 flavor Chinese herbal medicine, 175 grams, grind into fine powder after the oven dry, cross 100 mesh sieves and stir, tighten the lid mouth in the freshness protection package of packing into, put into the tight lid of container inner cap again.Difference according to neonate localized edema area position, get about Cortex Cinnamomi Radix Aconiti powder 60～80 grams, with the cooled vaseline oil furnishing ointment of dissolving, with cotton swab ointment is spread upon hard swollen position uniformly, be coated with the ointment edge outward and surpass hard swollen position 1～2cm, petrolatum oil gauze covers, cover nontoxic preservative film again, fix, change dressings every day 1～2 time with dressing, medication 5th～7 was a course of treatment, treated 4～5 courses of treatment altogether.

3, therapeutic evaluation standard: effectively: neonate extremity or whole body skin temperature gradually change warm, and temperature recovery is normal, and the local skin scleroderma neonatorum fades and moves back; Invalid: scleroderma neonatorum neonate hypothermia and skin scleroderma neonatorum do not have change.

4, therapeutic effect: use the Cortex Cinnamomi Radix Aconiti powder of neonatal scleredema of the present invention to treat 30 examples altogether, effective 28 examples of result account for 93%.Invalid 2 examples account for 7%.Effective percentage is 93%.

Claims (1)

1. external Cortex Cinnamomi Radix Aconiti powder that is used for neonatal scleredema, adopt Cortex Cinnamomi, Radix Aconiti, Flos Caryophylli, Radix Aconiti Kusnezoffii, Flos Carthami, Rhizoma Cyperi, Rhizoma Zingiberis, Radix Bupleuri, Cortex Magnoliae Officinalis, Rhizoma Curcumae, Poria, Pericarpium Citri Reticulatae Viride, rhizoma sparganic, the Rhizoma Atractylodis Macrocephalae, Galla Chinensis, when being classified as raw material, raw material stoving is ground into fine powder, cross 100 mesh sieves, mix homogeneously, promptly make medicated powder, it is characterized in that the raw material composition is by weight percentage: Cortex Cinnamomi 12～15%, Radix Aconiti 8～12%, Flos Caryophylli 5～8%, Radix Aconiti Kusnezoffii 7～10%, Flos Carthami 4～8%, Rhizoma Cyperi 4～7%, Rhizoma Zingiberis 3～6%, Radix Bupleuri 4～7%, Cortex Magnoliae Officinalis 3～6%, Rhizoma Curcumae 4～6%, Poria 5～7%, Pericarpium Citri Reticulatae Viride 8～12%, rhizoma sparganic 3～6%, the Rhizoma Atractylodis Macrocephalae 2～5%, Galla Chinensis 2～4%, Radix Angelicae Sinensis 2～5%.