CN102057914A - Bactericidal composition containing metconazole and antibiotic compound - Google Patents
Bactericidal composition containing metconazole and antibiotic compound Download PDFInfo
- Publication number
- CN102057914A CN102057914A CN201010607191XA CN201010607191A CN102057914A CN 102057914 A CN102057914 A CN 102057914A CN 201010607191X A CN201010607191X A CN 201010607191XA CN 201010607191 A CN201010607191 A CN 201010607191A CN 102057914 A CN102057914 A CN 102057914A
- Authority
- CN
- China
- Prior art keywords
- metconazole
- polyoxin
- jinggangmeisu
- kasugarnycin
- bactericidal composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a bactericidal composition containing metconazole and an antibiotic compound. The bactericidal composition contains an active ingredient A and an active ingredient B, wherein the active ingredient A is metconazole, the active ingredient B is selected from any one of the following bactericides: validamycin, polyoxin and kasugamycin, and the weigh part ratio of the active ingredient A to the active ingredient B is (1-64): (64-1). The composition can control various crop diseases, has remarkable synergistic action, enlarges the bactericidal spectrum, has higher activity to rice blast, powdery mildew, downy mildew, sheath blight, botrytis, leaf mold, fusarium wilt, plague and alternaria mali; in addition, agricultural chemical dosage, the residue of agricultural chemical on crops and environment pollution are reduced.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition that contains metconazole and antibiotics compound.
Background technology
Metconazole (Metconazole) is the trendy triazole bactericidal agent of Japanese Wu Yu chemical company in the early 1990s exploitation, molecular formula: C
17H
22ClN
3O, structural formula:
Metconazole is a C-14 demethylation enzyme inhibitor in the ergosterol biosynthesis.Though the mechanism of action is the same with other triazole bactericidal agents, activity profile then difference is bigger.Two kinds of isomer all have bactericidal activity, but that the cis activity is higher than is trans.The antifungal spectrum of metconazole is very extensive, and active splendid.The metconazole field is used and cereal septoria musiva, fusarium and handle rest fungus is planted disease remarkable effect is arranged.Metconazole is compared with traditional biocide agent, and dosage is extremely low and prevent and treat cereal to plant the disease scope very wide.
In the real process of agricultural production, the agent of metconazole list is used for a long time, and the problem that is easy to generate is the drug-fast generation of germ.And that the different cultivars composition carries out is composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery can produce good synergistic effect with metconazole and jinggangmeisu, polyoxin, kasugarnycin after composite, and still unexposed at home and abroad about the composite relevant report of metconazole and jinggangmeisu, polyoxin, kasugarnycin.
Summary of the invention
A kind of bactericidal composition that contains metconazole and antibiotics compound, comprise effective active component, auxiliary agent and filler, it is characterized in that: A, B ratio of weight and number are 1～64: 64～1, active components A is selected from metconazole, and active component B is selected from a kind of in antibiotics compound jinggangmeisu, polyoxin, the kasugarnycin.
Described a kind of bactericidal composition that contains metconazole and antibiotics compound is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 1～50: 50～1.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of metconazole and jinggangmeisu is 5～40: 5～50.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of metconazole and polyoxin is 5～40: 5～50.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of metconazole and kasugarnycin is 5～40: 5～50.
The ratio of weight and number of A, two kinds of active components of B is 64: 1～1: 64, and preferred ratio of weight and number is 16: 1～1: 16, and preferred ratio of weight and number is 8: 1～1: 8, and further preferred ratio of weight and number is 4: 1～1: 4.
Usually active weight percentage is 1～90% of a gross weight in the composition, and preferable is 10%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 1～90% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, binding agent or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described stabilizing agent is selected from one or more in sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, the polyethylene glycol diglycidyl ether;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, the defoamer etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent.
When making wetting powder, composition comprises following constituent content: metconazole 1～50%, active component B 1～50%, dispersant 5～10%, wetting agent 2～10%, filler 8～91%.
Active component metconazole, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: active component metconazole 1～50%, active component B 1～50%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～92%.
Active component metconazole, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
Comprise following constituent content when composition is made suspending agent: active component metconazole 1～30%, active component B 1～30%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active component metconazole, active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
The invention has the advantages that: after (1) metconazole and antibiotics compound are composite, have obviously lasting synergistic effect; (2) enlarged fungicidal spectrum, rice blast, powdery mildew, downy mildew, banded sclerotial blight, gray mold, leaf mold, fusarium wilt, eqpidemic disease, spot defoliation disease have all been had greater activity; (3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage; (4) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution.
Embodiment
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Metconazole and active component B (B is selected from a kind of of jinggangmeisu, polyoxin, kasugarnycin) are composite to target germ Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the target germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component metconazole and active component B (jinggangmeisu, polyoxin, kasugarnycin) shared ratio in combination;
A is a metconazole;
B is a kind of in jinggangmeisu, polyoxin, the kasugarnycin.
Implementation of an application example one
Metconazole and composite jinggangmycin are to the rice blast Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining metconazole, the former medicine of jinggangmeisu and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 metconazole, jinggangmeisu and composite toxicity test analysis of results table thereof to rice blast
As shown in Table 1, metconazole, jinggangmeisu are to the EC of rice blast
50Be respectively 0.87mg/L and 2.16mg/L.Metconazole and jinggangmeisu proportioning were at 64: 1 to 1: 64 o'clock, synergy ratio SR is all greater than 1.5, illustrating that metconazole and jinggangmeisu were mixed in the scope at 64: 1 to 1: 64 all shows synergistic effect, especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is more obvious, synergy ratio SR maximum when metconazole and jinggangmeisu weight ratio are 2: 1 wherein, synergistic effect is the most obvious.
Implementation of an application example two
Metconazole and polyoxin are composite to the wheat powdery mildew Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining metconazole, the former medicine of polyoxin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 metconazole, polyoxin and composite toxicity test analysis of results table thereof to wheat rust
As shown in Table 2, metconazole, polyoxin are to the EC of wheat rust
50Be respectively 1.02mg/L and 2.18mg/L.Metconazole and polyoxin proportioning were at 64: 1 to 1: 64 o'clock, synergy ratio SR is all greater than 1.5, illustrating that metconazole and polyoxin were mixed in the scope at 50: 1 to 1: 50 all shows synergistic effect, especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is more obviously outstanding, synergy ratio SR maximum when metconazole and polyoxin weight ratio are 1: 2 wherein, synergistic effect is the most obvious.
Implementation of an application example three:
Metconazole and kasugarnycin are composite to the cladosporium leaf and fruit mould of tomato Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining metconazole, the former medicine of kasugarnycin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 metconazole, kasugarnycin and composite toxicity test analysis of results table thereof to cladosporium leaf and fruit mould of tomato
As shown in Table 3, metconazole, kasugarnycin are to the EC of cladosporium leaf and fruit mould of tomato
50Be respectively 0.96mg/L and 2.63mg/L.Metconazole compares at 64: 1 to 1: 64 o'clock with kasugarnycin, synergy ratio SR is all greater than 1.5, illustrating that metconazole and kasugarnycin were mixed in the scope at 64: 1 to 1: 64 all shows synergistic effect, especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is more outstanding, synergy ratio SR maximum when metconazole and kasugarnycin weight ratio are 2: 1 wherein, synergistic effect is the most obvious.
Application Example four the implementation of Formulation Example
To further instruction of the present invention, the portion rate among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Example 1 25% metconazole jinggangmeisu wetting powder
Metconazole 5%, jinggangmeisu 20%, lignosulfonates 3%, soapberry powder 4%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 25% metconazole jinggangmeisu wetting powder.
Example 2 35% metconazole jinggangmeisu wetting powders
Metconazole 20%, jinggangmeisu 15%, polycarboxylate 3%, wetting and penetrating agent F 2%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 35% metconazole jinggangmeisu wetting powder.
Example 3 70% metconazole jinggangmeisu wetting powders
Metconazole 50%, jinggangmeisu 20%, aryl phenol polyoxyethylene succinate sulfonate 4%, spaonin powder 3%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 70% metconazole jinggangmeisu wetting powder.
Example 4 18% metconazole jinggangmeisu water dispersible granules
Metconazole 6%, jinggangmeisu 12%, lauryl sodium sulfate 5%, polyoxyethylene carboxylate 3%, aluminium chloride 0.5%, precipitated calcium carbonate add to 100%, the mixed 18% metconazole jinggangmeisu water dispersible granules that gets.
Example 5 27% metconazole jinggangmeisu water dispersible granules
Metconazole 18%, jinggangmeisu 9%, wetting and penetrating agent F 3%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4%, bentonite add to 100%, the mixed 27% metconazole jinggangmeisu water dispersible granules that gets.
Example 6 35% metconazole jinggangmeisu water dispersible granules
Metconazole 10%, jinggangmeisu 25%, spaonin powder 5%, alkyl benzene sulfonate calcium salt 4%, urea 1%, kaolin add to 100%, the mixed 35% metconazole jinggangmeisu water dispersible granules that gets.
Example 7 15% metconazole jinggangmeisu suspending agents
Metconazole 10%, jinggangmeisu 5%, polycarboxylate 5%, neopelex 5%, C
8～10Aliphatic alcohols 0.5%, methylcellulose 1%, propane diols 1.6%, deionized water add to 100%, the mixed 15% metconazole jinggangmeisu suspending agent that gets.
Example 8 20% metconazole jinggangmeisu suspending agents
Metconazole 16%, jinggangmeisu 4%, naphthalene sulfonic acid-formaldehyde condensation product 4%, silkworm excrement 3%, silicone compound 0.2%, polyvinylpyrrolidone 0.8%, polyethylene glycol 1.5%, deionized water add to 100%, the mixed 20% metconazole jinggangmeisu suspending agent that gets.
Example 9 45% metconazole jinggangmeisu suspending agents
Metconazole 40%, jinggangmeisu 5%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, neopelex 4%, C
10～20Saturated fat acids 0.5%, sodium phosphate trimer 1%, glycerine 1.5%, deionized water add to 100%, the mixed 45% metconazole jinggangmeisu suspending agent that gets.
Example 10 24% metconazole polyoxin wetting powders
Metconazole 8%, polyoxin 16%, polycarboxylate 3%, Nekal BX 4%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 24% metconazole polyoxin wetting powder.
Example 11 45% metconazole polyoxin wetting powders
Metconazole 30%, polyoxin 15%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, silkworm excrement 3%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 45% metconazole polyoxin wetting powder.
Example 12 50% metconazole polyoxin wetting powders
Metconazole 40%, polyoxin 10%, lignosulfonates 3%, soapberry powder 4%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 50% metconazole polyoxin wetting powder.
Example 13 20% metconazole polyoxin water dispersible granules
Metconazole 10%, polyoxin 10%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, spaonin powder 2%, urea 1%, attapulgite add to 100%, the mixed 20% metconazole polyoxin water dispersible granules that gets.
Example 14 30% metconazole polyoxin water dispersible granules
Metconazole 20%, polyoxin 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, wetting and penetrating agent F 4%, bentonite add to 100%, the mixed 30% metconazole polyoxin water dispersible granules that gets.
Example 15 40% metconazole polyoxin water dispersible granules
Metconazole 25%, polyoxin 15%, lignosulfonates 4%, soapberry powder 4%, ammonium sulfate 0.8%, kaolin add to 100%, the mixed 40% metconazole polyoxin water dispersible granules that gets.
Example 16 12% metconazole polyoxin suspending agents
Metconazole 4%, polyoxin 8%, polyoxyethylene carboxylate 4%, soapberry powder 3%, silicone oil 0.3%, xanthans 1%, glycerine 1.3%, deionized water add to 100%, the mixed 12% metconazole polyoxin suspending agent that gets.
Example 17 14% metconazole polyoxin suspending agents
Metconazole 10%, polyoxin 4%, alkyl benzene sulfonate calcium salt 3%, lauryl sodium sulfate 4%, silicone compound 0.5%, sodium phosphate trimer 1.2%, ethylene glycol 1.3%, deionized water add to 100%, the mixed 14% metconazole polyoxin suspending agent that gets.
Example 18 22% metconazole polyoxin suspending agents
Metconazole 15%, polyoxin 7%, polycarboxylate 3%, wetting and penetrating agent F 5%, silicone oil 0.2%, polyvinylpyrrolidone 0.9%, polyethylene glycol 1.6%, deionized water add to 100%, the mixed 22% metconazole polyoxin suspending agent that gets.
Example 19 18% metconazole kasugarnycin wetting powders
Metconazole 6%, kasugarnycin 12%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, silkworm excrement 3%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 18% metconazole kasugarnycin wetting powder.
Example 20 48% metconazole kasugarnycin wetting powders
Metconazole 30%, kasugarnycin 18%, lignosulfonates 3%, spaonin powder 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 48% metconazole kasugarnycin wetting powder.
Example 21 56% metconazole kasugarnycin wetting powders
Metconazole 50%, kasugarnycin 6%, polyoxyethylene carboxylate 3%, wetting and penetrating agent F 4%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 56% metconazole kasugarnycin wetting powder.
Example 22 9% metconazole kasugamycin water-dispersion granules
Metconazole 8%, kasugarnycin 1%, aryl phenol polyoxyethylene succinate sulfonate 3%, Nekal BX 4%, sodium sulphate 1%, bentonite add to 100%, the mixed 9% metconazole kasugamycin water-dispersion granule that gets.
Example 23 25% metconazole kasugamycin water-dispersion granules
Metconazole 20%, kasugarnycin 5%, aliphatic amine polyoxyethylene are phonetic 3%, wetting and penetrating agent F 3%, aluminium chloride 0.8%, attapulgite add to 100%, mixed 25% metconazole kasugamycin water-dispersion granule.
Example 24 44% metconazole kasugamycin water-dispersion granules
Metconazole 40%, kasugarnycin 4%, naphthalene sulfonic acid-formaldehyde condensation product 4%, soapberry powder 5%, urea 1.2%, bentonite add to 100%, the mixed 44% metconazole kasugamycin water-dispersion granule that gets.
Example 25 27% metconazole kasugarnycin suspending agents
Metconazole 9%, kasugarnycin 18%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4%, neopelex 3%, C
8～10Aliphatic alcohols 0.7%, gum Arabic 0.8%, glycerine 1.4%, deionized water add to 100%, the mixed 27% metconazole kasugarnycin suspending agent that gets.
Example 26 32% metconazole kasugarnycin suspending agents
Metconazole 20%, kasugarnycin 12%, alkyl benzene sulfonate calcium salt 3%, wetting and penetrating agent F 4%, silicone oil 0.2%, polyvinylpyrrolidone 1%, polyethylene glycol 1.7%, deionized water add to 100%, the mixed 32% metconazole kasugarnycin suspending agent that gets.
Example 27 35% metconazole kasugarnycin suspending agents
Metconazole 25%, kasugarnycin 10%, polyoxyethylene carboxylate 5%, soapberry powder 2%, silicone compound 0.5%, sodium phosphate trimer 0.6%, propane diols 1.2%, deionized water add to 100%, the mixed 35% metconazole kasugarnycin suspending agent that gets.
Application Example five metconazoles and jinggangmeisu and the composite control rice blast test of pesticide effectiveness thereof
This experimental establishment is in suburb, Guangxi province Liuzhou City, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 60g/L metconazole aqueous emulsion (commercial), 5% jinggangmeisu aqua (commercial).
The preceding investigation of medicine rice blast disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 4 metconazole, jinggangmeisu and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 4, can effectively prevent and treat rice blast behind metconazole and the composite jinggangmycin, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects, and rice sheath blight disease is had certain preventive effect.
Application Example six metconazoles and polyoxin and the composite control wheat powdery mildew test of pesticide effectiveness thereof
This experimental establishment is in the Yingshang County, Anhui Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 60g/L metconazole aqueous emulsion (commercial), 10% polyoxin wetting powder (commercial).
The investigation wheat powdery mildew state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 5 metconazole, polyoxin and the composite control wheat powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 5, can effectively prevent and treat wheat powdery mildew after metconazole and polyoxin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven metconazoles and kasugarnycin and the composite cladosporium leaf and fruit mould of tomato test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at Shaanxi Province's Changan District, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 60g/L metconazole aqueous emulsion (commercial), 2% kasugarnycin aqua (commercial).
The preceding investigation of medicine cladosporium leaf and fruit mould of tomato disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 6 metconazole, kasugarnycin and the composite cladosporium leaf and fruit mould of tomato test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 6, can effectively prevent and treat cladosporium leaf and fruit mould of tomato after metconazole and kasugarnycin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Claims (7)
1. bactericidal composition that contains metconazole and antibiotics compound, comprise effective active component, auxiliary agent and filler, it is characterized in that: two kinds of active component ratios of weight and number of A, B are 1～64: 64～1, described A is selected from metconazole, and B is selected from a kind of in antibiotics compound jinggangmeisu, polyoxin, the kasugarnycin.
2. bactericidal composition according to claim 1 is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 1～50: 50～1.
3. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of metconazole and jinggangmeisu is 5～40: 5～50.
4. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of metconazole and polyoxin is 5～40: 5～50.
5. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of metconazole and kasugarnycin is 5～40: 5～50.
6. bactericidal composition according to claim 1 is characterized in that: wherein the effective active component content accounts for 1～95% of gross weight.
7. bactericidal composition according to claim 6 is characterized in that: wherein the effective active component content accounts for 10～80% of gross weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010607191 CN102057914B (en) | 2010-12-27 | 2010-12-27 | Bactericidal composition containing metconazole and antibiotic compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010607191 CN102057914B (en) | 2010-12-27 | 2010-12-27 | Bactericidal composition containing metconazole and antibiotic compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102057914A true CN102057914A (en) | 2011-05-18 |
| CN102057914B CN102057914B (en) | 2013-07-24 |
Family
ID=43993591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010607191 Expired - Fee Related CN102057914B (en) | 2010-12-27 | 2010-12-27 | Bactericidal composition containing metconazole and antibiotic compound |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102057914B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103385243A (en) * | 2012-05-09 | 2013-11-13 | 陕西韦尔奇作物保护有限公司 | Bactericidal composition containing tiadinil and antibiotics |
| CN103563910A (en) * | 2013-10-23 | 2014-02-12 | 江苏丰登农药有限公司 | Bactericidal composition containing prothioconazole and validamycin and application thereof |
| CN105284821A (en) * | 2015-11-19 | 2016-02-03 | 南京农业大学 | Metconazole-containing pesticide composition for preventing and treating wheat head blight and use thereof |
| CN106172423A (en) * | 2016-07-15 | 2016-12-07 | 郭正 | Jingganmycin and the Recompounded pesticide of metconazole and the application in Semen Tritici aestivi is prevented and treated thereof |
| CN108651464A (en) * | 2018-07-20 | 2018-10-16 | 南京南农农药科技发展有限公司 | The suspending agent of composite bactericide and preparation method thereof of jinggangmycin A and metconazole |
| US20190116790A1 (en) * | 2016-05-10 | 2019-04-25 | Nanjing Agricultural University | Jinggangmycin and Ipconazole Fungicidal Composition and Applications Thereof |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106719744A (en) * | 2016-11-02 | 2017-05-31 | 深圳诺普信农化股份有限公司 | Bactericidal composition and its application |
| WO2022185037A1 (en) * | 2021-03-01 | 2022-09-09 | UPL Corporation Limited | Agricultural composition comprising kasugamycin |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101410017A (en) * | 2005-12-13 | 2009-04-15 | 先正达参股股份有限公司 | Plant growth regulating and fungicidal compositions |
| WO2009068606A2 (en) * | 2007-11-30 | 2009-06-04 | Janssen Pharmaceutica Nv | Combinations of fungicidal triazoles and pyrion compounds |
| CN101874492A (en) * | 2010-06-01 | 2010-11-03 | 江苏七洲绿色化工股份有限公司 | Bactericidal composition containing penconazole and validamycin A and preparation method thereof |
-
2010
- 2010-12-27 CN CN 201010607191 patent/CN102057914B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101410017A (en) * | 2005-12-13 | 2009-04-15 | 先正达参股股份有限公司 | Plant growth regulating and fungicidal compositions |
| WO2009068606A2 (en) * | 2007-11-30 | 2009-06-04 | Janssen Pharmaceutica Nv | Combinations of fungicidal triazoles and pyrion compounds |
| CN101874492A (en) * | 2010-06-01 | 2010-11-03 | 江苏七洲绿色化工股份有限公司 | Bactericidal composition containing penconazole and validamycin A and preparation method thereof |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103385243A (en) * | 2012-05-09 | 2013-11-13 | 陕西韦尔奇作物保护有限公司 | Bactericidal composition containing tiadinil and antibiotics |
| CN103385243B (en) * | 2012-05-09 | 2016-05-18 | 陕西韦尔奇作物保护有限公司 | A kind of bactericidal composition containing tiadinil and antibiotics |
| CN103563910A (en) * | 2013-10-23 | 2014-02-12 | 江苏丰登农药有限公司 | Bactericidal composition containing prothioconazole and validamycin and application thereof |
| CN103563910B (en) * | 2013-10-23 | 2015-04-01 | 江苏丰登作物保护股份有限公司 | Bactericidal composition containing prothioconazole and validamycin and application thereof |
| CN105284821A (en) * | 2015-11-19 | 2016-02-03 | 南京农业大学 | Metconazole-containing pesticide composition for preventing and treating wheat head blight and use thereof |
| WO2017084249A1 (en) * | 2015-11-19 | 2017-05-26 | 南京农业大学 | Metconazole-containing pesticide composition for preventing and treating fusarium head blight and application thereof |
| US9949479B2 (en) * | 2015-11-19 | 2018-04-24 | Nanjing Agricultural University | Metconazole-containing pesticide composition for preventing and controlling fusarium head blight and application thereof |
| AU2016356037B2 (en) * | 2015-11-19 | 2018-06-14 | Nanjing Agricultural University | Metconazole-containing pesticide composition for preventing and treating fusarium head blight and application thereof |
| US20190116790A1 (en) * | 2016-05-10 | 2019-04-25 | Nanjing Agricultural University | Jinggangmycin and Ipconazole Fungicidal Composition and Applications Thereof |
| CN106172423A (en) * | 2016-07-15 | 2016-12-07 | 郭正 | Jingganmycin and the Recompounded pesticide of metconazole and the application in Semen Tritici aestivi is prevented and treated thereof |
| CN108651464A (en) * | 2018-07-20 | 2018-10-16 | 南京南农农药科技发展有限公司 | The suspending agent of composite bactericide and preparation method thereof of jinggangmycin A and metconazole |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102057914B (en) | 2013-07-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102057914B (en) | Bactericidal composition containing metconazole and antibiotic compound | |
| CN102017955B (en) | Bactericidal composite containing metconazole and methoxy acrylate compounds | |
| CN102224822B (en) | Microbicidal composition containing chloroisobromine cyanuric acid and antibiotics | |
| CN102302026A (en) | Bactericidal composition containing pyraclostrobin and antibiotic compounds | |
| CN102067857A (en) | Fungicide combination containing polyoxin | |
| CN102067851B (en) | Antibacterial composition containing polyoxin and methoxyacrylate compound | |
| CN102057908B (en) | Bactericidal composite containing dithianon and methoxy acrylic esters | |
| CN102138562B (en) | Antibacterial composition containing polyoxin and amide compounds | |
| CN103734158A (en) | Polyoxins-containing bactericidal composition | |
| CN102057909B (en) | Bactericidal composition containing triflumizole and antibiotic compounds | |
| CN102007934B (en) | Bactericidal composition containing phosethyl-Al and antibiotic compound | |
| CN102204552A (en) | Antibacterial composition containing enestroburin and antibiotic compound | |
| CN102090407B (en) | Bactericidal composition containing bitertanol and antibiotic type compound | |
| CN102057927A (en) | Bactericidal composition containing captan and triazole compounds | |
| CN102037974B (en) | Sterilization composition containing triticonazole and methoxyl acrylate | |
| CN102047893B (en) | Bactericidal composition containing captan and antibiotic compound | |
| CN102217618B (en) | Bactericidal composition containing trifloxystrobin and antibiotic compounds | |
| CN103651445B (en) | Bactericidal composition containing polyoxin and methoxyacrylate | |
| CN102027935B (en) | Bactericidal composition containing dithianone and triazole compound | |
| CN102204544A (en) | Picoxystrobin-containing synergic bactericidal composition | |
| CN102067862A (en) | Ipconazole-containing bactericidal composition | |
| CN103719086A (en) | Sterilization composite containing trifloxystrobin and antibiotics compound | |
| CN102067859A (en) | Bactericidal composition containing ipconazole and thiocarbamate compound | |
| CN102138558B (en) | Antibacterial composition containing fenbuconazole and antibiotic compounds | |
| CN102027938B (en) | Bactericidal composition containing bitertanol and strobilurin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP02 | Change in the address of a patent holder |
Address after: 715500 Pucheng County of Shaanxi Province agricultural base industrial park Patentee after: Shaanxi Meibang Pesticide Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Patentee before: Shaanxi Meibang Pesticide Co., Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130724 Termination date: 20171227 |