CN101999646A - Mouth-dissolved donkey-hide gelatin special for pregnant and parturient women and preparation method thereof - Google Patents

Mouth-dissolved donkey-hide gelatin special for pregnant and parturient women and preparation method thereof Download PDF

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CN101999646A
CN101999646A CN2010102859011A CN201010285901A CN101999646A CN 101999646 A CN101999646 A CN 101999646A CN 2010102859011 A CN2010102859011 A CN 2010102859011A CN 201010285901 A CN201010285901 A CN 201010285901A CN 101999646 A CN101999646 A CN 101999646A
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donkey
hide gelatin
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CN101999646B (en
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桑青
秦东风
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Liaocheng University
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Liaocheng University
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Abstract

The invention discloses a preparation method of a mouth-dissolved donkey-hide gelatin special for pregnant and parturient women, comprising the steps of: dissolving the donkey-hide gelatin in function material extract, wherein the dosage of the donkey-hide gelatin is 1-10% of the weight of the function material extract; degassing the obtained material in a mould; freezing at a temperature of -15 DEG C to -80 DEG C for 2-24 hours; and freezing and drying in vacuum, cutting, and packing. The mouth-dissolved donkey-hide gelatin for pregnant and parturient women has the advantages of simple preparation method, special flavor, and convenient taking and carrying.

Description

Pregnant and lying-in women's special use containing donkey-hide gelatin and preparation method
Technical field
The present invention relates to field of health care food, particularly relate to a kind of containing of pregnant and lying-in women donkey-hide gelatin series of products and preparation method thereof.
Background technology
The skin that donkey-hide gelatin derives from Chordata Mammalia equine (Equidae) animal donkey (Equus asinus L.) concentrates the solid gum that forms through decocting, and its proterties is rectangle or square block, and pitchy is glossy.Matter is hard and crisp, and section light, fragment are looked illumination and be brown translucent.Gas is little, and it is little sweet to distinguish the flavor of." donkey-hide gelatin, herbal classic is top grade, claims " obeying the beneficial gas of making light of one's life by commiting suicide for a long time " for the record of Li Shizhen (1518-1593 A.D.) Compendium of Material Medica.Great scape is said: ' going out the Donga, so the name donkey-hide gelatin ' ".Shen is drawn together " mengxibitan " and said: " well water, property become down, and be clear and heavy.Get well water and boil glue, the donkey-hide gelatin of meaning ".Donkey-hide gelatin is an orthodox school to originate from the Donga County, Shandong since ancient times, the history in existing more than 2500 year.Donkey-hide gelatin and genseng, pilose antler also claim " nourishing three is big precious ", and nourishing yin and supplementing blood is promoted longevity.The collagen of the small-molecular weight that the main component of donkey-hide gelatin is made up of 18 seed amino acids such as lysine, glycine, arginine (comprise 8 kinds of needed by human and self can not synthesize amino acid) and the peptone that hydrolysis forms, peptide etc., and contain the trace element that kinds more than 20 such as iron, zinc, calcium, strontium benefit human body.Donkey-hide gelatin is flat, flavor is sweet, has the enriching yin of enriching blood, and moisturizes effects such as hemostasis.
Traditional usage one of donkey-hide gelatin is for being used as medicine, and two convert clothes for molten, take inconvenience.The Chinese patent literature of publication number CN101366515 (application number 200810157422.4) discloses a kind of donkey-hide gelatin and holothurian product and preparation method thereof, comprising two kinds of raw materials of donkey-hide gelatin and holothurian. the Chinese patent literature of publication number CN 101543569A (application number 200910000327.8) discloses a kind of donkey-hide gelatin nourishing-paste and preparation method thereof, be with the Radix Astragali, cultivated land, the dried rhizome of rehmannia, mulberry leaf, dried orange peel is soaked in water, make solution and Chinese yam, Poria cocos, the fruit of Chinese wolfberry mixes concentrated, adds donkey-hide gelatin, rock sugar, the Semen sesami nigrum of pulverizing, walnut kernel stirs evenly back adding matrix starch and the anticorrisive agent sorbic acid is made.The Chinese patent literature of publication number CN 1895279A (application number 200610044865.3) discloses the preparation method and the donkey-hide gelatin product thereof of planting the nano ass hide glue powder, at first polyethylene glycol is added purified water and melts, and makes the A component; Then the chunky shape donkey-hide gelatin is joined in the A component, make the B component; Again lecithin is joined in the B component, make the C component; Subsequently the C component is dissolved in the purified water, filtering with microporous membrane, gained nanometer filtrate is the D component; With D component spray-drying successively, freeze drying, vacuum Rotary drying, make the nano ass hide glue powder at last.After capsule or pill or pill or tablet that donkey-hide gelatin powder and F component are mixed and made into by arbitrary proportion, wherein, the F component is any one in extract, fine powder or the ultramicro grinding fine powder of melissa powder, American Ginseng, genseng, prepared rhizome of rehmannia, hawthorn, Radix Codonopsis, Chinese yam, pseudo-ginseng, longan, matrimony vine, Radix Angelicae Sinensis, the fleece-flower root, and perhaps more than one mix by arbitrary proportion.There are shortcomings such as taking inconvenience, poor, the difficult clothes for a long time of mouthfeel in the disclosed donkey-hide gelatin product of above-mentioned patent documentation and other existing donkey-hide gelatin products.
Summary of the invention
At the deficiencies in the prior art, the purpose of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, function difference, mouthfeel are good, easy serial donkey-hide gelatin product of clothes and preparation method thereof for a long time.These series of products have strengthening the spleen and stomach, regulate the flow of vital energy help digestion, the remarkable result of nourishing blood and preventing abortion, can satisfy different pregnant and lying-in women crowds' needs.
Technical scheme of the present invention is:
The preparation method of containing of pregnant and lying-in women's special use donkey-hide gelatin, step is as follows:
(1) donkey-hide gelatin is dissolved in the functional mass extract, the consumption of donkey-hide gelatin is 1~10% of a functional mass extract weight;
(2) (1) gained material is put the degassing in the mould (stainless steel disc or porcelain dish all can);
℃ (3)-15----80 ℃ are freezing 2~24 hours;
(4) vacuum freeze drying, cutting, packing gets final product.
Aforesaid preparation method, preferably scheme is, and described functional mass extract is that following raw material adds water 1500-2200 part, decocts 20-45 minute, and filtrate concentrates and gets; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material, be weight portion:
A group: Chinese yam 15-25 part, Poria cocos 8-15 part, fructus amomi 4-8 part, Buddha's hand 2-5 part, Caulis Perillae 4-8 part, Fructus Hordei Germinatus 2-6 part (preferred coloured malt), hawthorn 2-5 part (preferably living hawthorn), date 15-25 part, dried orange peel 2-5 part;
B group: sealwort 15-25 part, Chinese yam 25-35 part, Radix Angelicae Sinensis 8-12 part, radix pseudostellariae 8-14 part, black fungus 8-12 part, peach kernel 8-12 part, Poria cocos 8-12 part, dried orange peel 8-10 part, fructus amomi 6-10 part, rhizoma zingiberis 2-5 part, date 15-25 part.
More preferably, the raw material of two groups of A, B is respectively:
A group: Chinese yam 16-22 part, Poria cocos 10-12 part, fructus amomi 5-6 part, Buddha's hand 3-4 part, dried orange peel 3-4 part, Caulis Perillae 5-7 part, Fructus Hordei Germinatus 3-5 part (preferred coloured malt), hawthorn 3-4 part (preferably living hawthorn), date 18-20 part;
B group: sealwort 18-20 part, Chinese yam 25-30 part, Radix Angelicae Sinensis 9-10 part, radix pseudostellariae 10-12 part, black fungus 9-10 part, peach kernel 9-10 part, Poria cocos 9-10 part, dried orange peel 9-10 part, fructus amomi 6-8 part, rhizoma zingiberis 2-3 part, date 18-20 part.
Most preferably, the raw material of two groups of A, B is respectively:
A group: 20 parts of Chinese yams, 10 parts in Poria cocos, 6 parts of fructus amomis, 3 parts of Buddha's hands, 6 parts of Caulis Perillaes, 3 parts of coloured malts, 3 parts of living hawthorn, 20 parts in date, 4 parts of dried orange peels;
B group: 20 parts of sealworts, 30 parts of Chinese yams, 10 parts of Radix Angelicae Sinensis, 10 parts of radix pseudostellariaes, 10 parts of black fungus, 10 parts in peach kernel, 10 parts in Poria cocos, 10 parts of dried orange peels, 6 parts of fructus amomis, 3 parts of rhizoma zingiberis, 20 parts in date.
Aforesaid preparation method, preferred scheme is that the consumption of donkey-hide gelatin is 3~7% of a functional mass extract weight in the step (1).
Aforesaid preparation method, preferred scheme is that step (3) cryogenic temperature is-30 ℃----60 ℃, cooling time is 12-20 hour.More preferably, cryogenic temperature is-40 ℃----50 ℃, cooling time is 15-18 hour.
Aforesaid preparation method, preferred scheme are also to add an amount of sweet substance in step (1) gained material.Described sweet substance is a kind of in sucrose, fructose, honey, oligoisomaltose, soyabean oligosaccharides, the hydroxyl isomaltulose or several.
Aforesaid preparation method, preferred scheme are also to add an amount of black sesame powder and/or walnut meat powder in step (1) gained material.
Above-mentioned preparation method is simple, product special flavour uniqueness, taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
1, the related all material of this method is all medicine-food two-purpose, and is without any side effects;
2, this prescription meets traditional Chinese medicine principle and pregnant and lying-in women's body and mind characteristics fully, under the prerequisite of general principle, can different prescriptions be arranged according to different situations, the function difference;
3, this method can be added flavor enhancement (sweet substance) targetedly to adapt to the demand of different special populations;
4, travel on official business and carry taking convenience, promptly change, do not need water, be easy to quantitatively take for a long time to mouth.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.The medicine-food two-purpose material that the used functional mass of the present invention relates to and the main pharmacology of Chinese medicine material are as follows:
Donkey-hide gelatin: the property of medicine is sweet, and is flat.Return lung, liver, kidney channel.But medicine-food two-purpose, " donkey-hide gelatin, herbal classic is top grade, claims " obeying the beneficial gas of making light of one's life by commiting suicide for a long time " for the record of Li Shizhen (1518-1593 A.D.) Compendium of Material Medica.Main effect is the enriching yin of enriching blood, and moisturizes hemostasis.It is sallow to can be used for the general crowd and the deficiency of blood, dizzy palpitaition, and the flesh impotence is unable, dysphoria and insomnia, endogenous deficient wind, xeropulmonary cough, the labor spitting of blood of coughing, the haematemesis hematuria diseases such as uterine bleeding, vaginal bleeding during pregnancy of having blood in stool.Chinese yam: the property of medicine is sweet, and is flat.Return spleen, lung, kidney channel.But medicine-food two-purpose is according to Shennong's Herbal record Chinese yam " bowl spares, beneficial strength, longue meat ".According to Compendium of Material Medica record Chinese yam " kidney-nourishing gas, strengthening the spleen and stomach ".Main effect is the tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, and the puckery essence of kidney tonifying reduces blood sugar, promotes longevity.Can be used for general crowd and syndrome of spleen deficiency, deficiency syndrome of the lung card, nephrasthenia syndrome, the syndrome of deficiency of both qi and yin etc. of quenching one's thirst.Date: the property of medicine is sweet, temperature.Return spleen, stomach warp.But medicine-food two-purpose " is supported spleen " according to Shennong's Herbal record date in the peace.According to " Mingyi Bielu " record date " tonifying middle-Jiao and Qi, brute force are removed unhappy ".Main effect is tonifying middle-Jiao and Qi, nourishing blood and tranquilization.Can be used for general crowd and insufficiency of the spleen, cards such as consumptive disease is unhappy, insomnia.Hawthorn: property of medicine acid, sweet, tepor.Return spleen, stomach, Liver Channel; But medicine-food two-purpose " is changed diet, the meat Ji , Disorder lump in the abdomen that disappears, the full acid regurgitation of phlegm and retained fluid ruffian, stagnant blood distending pain according to Compendium of Material Medica record hawthorn." main effect is promoting digestion and removing indigestion, the promoting the circulation of qi stasis of blood of loosing.Can be used for cards such as general crowd and eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia.Radix pseudostellariae: the property of medicine is sweet, little hardship, and tepor is gone into the heart, spleen, lung three warps.Main effect is for mending strengthening spleen and lung; Nourishing generate fluid can be used for general crowd and insufficiency of the spleen food is few, palpitaition, and palpitation, oedema is quenched one's thirst, the tired card that waits of spirit.Dried orange peel: property of medicine suffering, hardship, temperature.Return spleen, lung channel.But medicine-food two-purpose, main effect is a regulating qi-flowing for strengthening spleen, in the accent, eliminating dampness is reduced phlegm.Can be used for the abdominal fullness and distention of the general crowd and the taste stagnation of the circulation of vital energy or pain, indigestion.Abdominal distension uncomfortable in chest in the wet turbid resistance, vomiting, hiccup card, indigestion and loss of appetite loose stool, phlegm disease such as wet.Poria cocos: the property of medicine is sweet, light, and is flat.The thoughts of returning home, spleen, kidney channel.Main effect is eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative.Can be used for difficult urination, oedema turgor, phlegm and retained fluid cough contrary, vomiting, insufficiency of the spleen food less, have loose bowels, disease such as palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea.Fructus amomi: flavor is hot; Warm in nature.Return spleen, stomach, kidney channel.Main effect is the dampness elimination appetizing, and warming spleen and stopping diarrha, it is antiabortive to regulate the flow of vital energy.Can be used for turbi damp obstructing in middle-JIAO, the gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, and vomiting is had loose bowels, pernicious vomiting, cards such as fetal irritability.Modern pharmacological research shows: this product decoction can strengthen the function of stomach, promotes secretion of digestive juice, can promote intestinal movement, discharges the pneumatosis in the digest tube, can play and help digest, and eliminates the effect of intestinal tympanites.Caulis Perillae: property of medicine suffering, temperature.Return lung, the spleen channel.Main effect is a regulating the flow of QI to ease the stomach, and pain relieving is antiabortive.It is vexed to be used for chest diaphragm ruffian, gastral cavity pain, belch vomiting, fetal irritability.Fructus Hordei Germinatus: the property of medicine is sweet, and is flat.Return spleen, stomach warp.Main effect is a promote qi circulation digestion promoting, and spleen benefiting and stimulating the appetite moves back newborn dissipate-swelling.Can be used for dyspepsia and do not disappear, abdominal distention, insufficiency of the spleen food is few, and newborn sweat smoulders, swollen breasts, women's ablactation, the logical breast of Fructus Hordei Germinatus strengthening the spleen and stomach.It is few to be used for insufficiency of the spleen food, and newborn sweat smoulders.The delaactation of coloured malt promote qi circulation digestion promoting.Be used for dyspepsia and do not disappear, women's ablactation.The melanoidin malt relieving dyspepsia.Be used for dyspepsia and do not disappear, abdominal distention.Sealwort: the property of medicine is sweet, and is flat.Return spleen, lung, kidney channel.Main effect is a boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing.Can be used for the lung-dryness syndrome due to yin deficiency, the phthisical cough chronic cough of few phlegm of dry cough and lung-kidney deficiency.This product is sweet flat, can support lung yin, beneficial lung qi.This product can not only nourishing lung and kidney the moon, and can invigoration spleen qi spleen the moon, the earth generating metal of benefit is arranged, mends the day after tomorrow to support congenital effect.The labor that also should the be used for lung-kidney deficiency chronic cough of coughing.Effect relaxes, and can singly obey for a long time with enduring cream; Should be used for the insufficiency of the spleen cloudy card of hindering.This product energy invigoration spleen qi is supported spleen the moon again.Cure mainly the sallow complexion of spleen deficiency of both qi and yin, sleepy weak, dry food less, be hard and dry.This product energy reinforcing both QI and YIN, list are used or are used together with the air making-up and spleen enlivening medicine; Deficiency of kidney-essence.This product energy benefiting kidney-essence, delaying sanility improves early ageing symptoms such as dizziness, soreness and weakness of waist and knees, poliosis.Radix Angelicae Sinensis: the property of medicine is sweet, hot, temperature.Return liver, the heart, the spleen channel.Main effect is a tonifying blood and regulating menstruation, and promoting blood circulation and stopping pain relaxes bowel.Can be used for sallow, the dizzy palpitaition of the deficiency of blood, irregular menstruation, through closing dysmenorrhoea, asthenia cold abdominalgia, the dry constipation of intestines, arthralgia due to wind-dampness, injury from falling down, ulcer sores.Arillus longan: nature and flavor are sweet, temperature.The thoughts of returning home, the spleen channel.But medicine-food two-purpose is according to " daily book on Chinese herbal medicine " record arillus longan " peaceful heart of intelligence development." " must join book on Chinese herbal medicine " think: " beneficial taste are preserved painstaking effort to longan, and moisturizing viscera is controlled palpitation." " Quanzhou book on Chinese herbal medicine " think: longan " establishing-Yang benefit gas, tonifying spleen and stomach." main effect is tonifying heart and spleen, nourishing blood and tranquilization, invigorating the spleen to arrest diarrhea, inducing diuresis to reduce edema etc.Can be used for sallow, the illness such as body void after being ill of general crowd and insufficiency of vital energy and blood, palpitation and severe palpitation, forgetful insomnia, neurasthenia, the deficiency of blood.Lily: sweet, little hardship of distinguishing the flavor of; Cool in nature.Return lung, the heart channel of Hang-Shaoyin.But medicine-food two-purpose, main effect: Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.Can be used for deficiency of Yin chronic cough, blood-stained sputum; After the warm heat disease, waste heat is not to the greatest extent, and is wandering, forgetful dreaminess; Deficiency of both vital energy and Yin, diseases such as constipation.Spina date seed: it is sweet to distinguish the flavor of, and property is flat.The thoughts of returning home, lung, the spleen channel.Main effect is: nourish heart, calm the nerves, arrest sweating.Can be used for diseases such as deficiency of YIN-blood, vexed insomnia, the empty spontaneous perspiration of body.Black fungus: it is sweet to distinguish the flavor of, and property is flat.Return lung, stomach, large intestine channel, but medicine-food two-purpose.The function cooling blood and hemostasis, enriching the blood to restore normal menstruation, sore is held back in pain relieving.Be used under spitting of blood, uterine bleeding, the band, postpartum the deficiency of blood, waist soreness, brothers take out the dry disease such as puckery of fiber crops, stool.Rhizoma zingiberis: property of medicine suffering, heat are returned spleen, the heart, lung channel.Main effect is a warming spleen and stomach for dispelling cold, and Hui Yang promotes blood circulation, warming lung to reduce watery phlegm.Peach kernel: property of medicine hardship, sweet, flat.The thoughts of returning home, liver, large intestine channel.Main effect is a promoting blood circulation, relaxes bowel, and is relieving cough and asthma.Be used for hemostasis through close, disease such as dysmenorrhoea, post partum longtime lochia, underbelly pain.Buddha's hand: property of medicine suffering, hardship, temperature is returned liver, spleen, stomach, lung channel.Main effect is a soothing liver-qi stagnation, regulate the flow of vital energy and in, eliminating dampness and eliminating phlegm.It is many to be used for liver depression distending pain in the chest and hypochondrium, stagnation of the circulation of vital energy epigastric pain, chronic cough phlegm, disease such as have a pain uncomfortable in chest.The hot row of this product hardship is let out, kind soothing liver-qi stagnation, promoting qi circulation and relieving pain, fragrant odour, can be amusing regulate the flow of vital energy and in lead stagnant.
The present invention is that raw material adopts traditional combination principle and the modern Chinese herbal medicine pharmacological experiments of the traditional Chinese medical science by above medicine-food two-purpose material and Chinese medicine, adopt different prescriptions, can beneficial gas, invigorating the spleen, enrich blood, the tire of rather feeling at ease, nourishing the stomach and stomach, regulate the flow of vital energy that to help digestion be main, with the honey seasoning, be applicable to maternity dress usefulness, help to improve the pregnancy period feel sick desire to tell, symptoms such as anorexia, palpitation; Can also strengthening the spleen and replenishing qi, tonify the blood and arrest bleeding, pain relieving is main in the temperature, is applicable to maternity clothing usefulness, helps to improve symptoms such as deficiency of qi and blood in postpartum, lochiorrhagia.
The preparation method of embodiment 1 containing of pregnant and lying-in women's special use donkey-hide gelatin
(1) preparation functional mass extract: take off and state raw material and add water 1500g, decocted 20 minutes, filtrate is concentrated; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material:
A group: Chinese yam 15g, Poria cocos 8g, fructus amomi 4g, Buddha's hand 2g, Caulis Perillae 4g, dried orange peel 2g, coloured malt 2g, living hawthorn 2g, date 15g;
B group: sealwort 15g, Chinese yam 25g, Radix Angelicae Sinensis 8g, radix pseudostellariae 8g, black fungus 8g, peach kernel 8g, Poria cocos 8g, dried orange peel 8g, fructus amomi 6g, rhizoma zingiberis 2g, date 15g.
(2) containing of preparation pregnant and lying-in women special use donkey-hide gelatin, step is as follows:
A, get donkey-hide gelatin 15g, 15g honey is dissolved in two kinds of different functional mass extracts respectively;
B, B gained material put in the mould outgas;
C ,-80 ℃ are freezing 2 hours;
D, vacuum freeze drying, cutting, packing can obtain pregnant or special-purpose the containing donkey-hide gelatin of puerpera.
The preparation method of embodiment 2 containing of pregnant and lying-in women's special use donkey-hide gelatin
(1) preparation functional mass extract: take off and state raw material and add water 2200g, decocted 45 minutes, filtrate is concentrated; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material:
A group: Chinese yam 25g, Poria cocos 15g, fructus amomi 8g, Buddha's hand 5g, Caulis Perillae 8g, Fructus Hordei Germinatus 6g, hawthorn 5g, date 25g, dried orange peel 5g;
B group: sealwort 25g, Chinese yam 35g, Radix Angelicae Sinensis 10g, radix pseudostellariae 10g, black fungus 12g, peach kernel 10g, Poria cocos 12g, dried orange peel 6g, fructus amomi 6g, rhizoma zingiberis 5g, date 25g.
(2) containing of preparation pregnant and lying-in women special use donkey-hide gelatin, step is as follows:
A, get donkey-hide gelatin 220g, 20g honey is dissolved in two kinds of different functional mass extracts respectively;
B, in B gained material, add black sesame powder and each 10g of walnut meat powder, put in the mould and outgas;
C ,-15 ℃ are freezing 24 hours;
D, vacuum freeze drying, cutting, packing can obtain pregnant or special-purpose the containing donkey-hide gelatin of puerpera.
The preparation method of embodiment 3 containing of pregnant and lying-in women's special use donkey-hide gelatin
(1) preparation functional mass extract: take off and state raw material and add water 1800g, decocted 35 minutes, filtrate is concentrated; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material:
A group: Chinese yam 16g, Poria cocos 10g, fructus amomi 5g, Buddha's hand 3g, Caulis Perillae 5g, Fructus Hordei Germinatus 3g, hawthorn 3g, date 18g, dried orange peel 3g;
B group: sealwort 18g, Chinese yam 25g, Radix Angelicae Sinensis 9g, radix pseudostellariae 10g, black fungus 9g, peach kernel 9g, Poria cocos 9g, dried orange peel 9g, fructus amomi 6g, rhizoma zingiberis 2g, date 18g.
(2) containing of preparation pregnant and lying-in women special use donkey-hide gelatin, step is as follows:
A, get donkey-hide gelatin 54g and be dissolved in two kinds of different functional mass extracts respectively;
B, add honey 15g, put in the mould and outgas to B gained material;
C ,-60 ℃ are freezing 12 hours;
D, vacuum freeze drying, cutting, packing can obtain pregnant or special-purpose the containing donkey-hide gelatin of puerpera.
The preparation method of embodiment 4 containing of pregnant and lying-in women's special use donkey-hide gelatin
(1) preparation functional mass extract: take off and state raw material and add water 2000g, decocted 40 minutes, filtrate is concentrated; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material:
A group: Chinese yam 22g, Poria cocos 12g, fructus amomi g, Buddha's hand 4g, Caulis Perillae 7g, Fructus Hordei Germinatus 5g, hawthorn 4g, date 20g, dried orange peel 4g;
B group: sealwort 20g, Chinese yam 30g, Radix Angelicae Sinensis 10g, radix pseudostellariae 12g, black fungus 10g, peach kernel 10g, Poria cocos 10g, dried orange peel 10g, fructus amomi 8g, rhizoma zingiberis 3g, date 20g.
(2) containing of preparation pregnant and lying-in women special use donkey-hide gelatin, step is as follows:
A, get donkey-hide gelatin 140g and be dissolved in two kinds of different functional mass extracts respectively;
B, B gained material put in the mould outgas;
C ,-40 ℃ are freezing 18 hours;
D, vacuum freeze drying, cutting, packing can obtain pregnant or special-purpose the containing donkey-hide gelatin of puerpera.
The preparation method of embodiment 5 containing of pregnant and lying-in women's special use donkey-hide gelatin
(1) preparation functional mass extract: take off and state raw material and add water 1600g, decocted 30 minutes, filtrate is concentrated; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material:
A group: Chinese yam 20g, Poria cocos 10g, fructus amomi 6g, Buddha's hand 3g, Caulis Perillae 6g, Fructus Hordei Germinatus 3g, hawthorn 3g, date 20g, dried orange peel 4g;
B group: sealwort 20g, Chinese yam 30g, Radix Angelicae Sinensis 10g, radix pseudostellariae 10g, black fungus 10g, peach kernel 10g, Poria cocos 10g, dried orange peel 10g, fructus amomi 6g, rhizoma zingiberis 3g, date 20g.
(2) containing of preparation pregnant and lying-in women special use donkey-hide gelatin, step is as follows:
A, get donkey-hide gelatin 80g and be dissolved in two kinds of different functional mass extracts respectively;
B, add soyabean oligosaccharides 20g, put in the mould and outgas to B gained material;
C ,-50 ℃ are freezing 15 hours;
D, vacuum freeze drying, cutting, packing can obtain pregnant or special-purpose the containing donkey-hide gelatin of puerpera.
The preparation method of embodiment 6 containing of pregnant and lying-in women's special use donkey-hide gelatin
(1) preparation functional mass extract: take off and state raw material and add water 2200g, decocted 45 minutes, filtrate is concentrated; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material:
A group: Chinese yam 25g, Poria cocos 15g, fructus amomi 8g, Buddha's hand 5g, Caulis Perillae 8g, Fructus Hordei Germinatus 6g, hawthorn 5g, date 25g, dried orange peel 5g; (this can add spina date seed 8-12g according to the clinical practice situation).
B group: sealwort 25g, Chinese yam 35g, Radix Angelicae Sinensis 10g, radix pseudostellariae 10g, black fungus 12g, peach kernel 10g, Poria cocos 12g, dried orange peel 6g, fructus amomi 6g, rhizoma zingiberis 5g, date 25g, (this can add arillus longan 8-12g, spina date seed 12-16g, lily 2-4g according to the clinical practice situation).
(2) containing of preparation pregnant and lying-in women special use donkey-hide gelatin, step is as follows:
A, get donkey-hide gelatin 220g, 20g honey is dissolved in two kinds of different functional mass extracts respectively;
B, in B gained material, add black sesame powder and each 10g of walnut meat powder, put in the mould and outgas;
C ,-15 ℃ are freezing 24 hours;
D, vacuum freeze drying, cutting, packing can obtain pregnant or special-purpose the containing donkey-hide gelatin of puerpera.
The application of test example 1 embodiment 5, A group raw produce
Have 46 maternity dress usefulness year July in July, 2006-2010, and the age is at 22 years old~35 years old, 25.6 years old mean age, pregnant time 2~8 months.Inclusion criteria: have with next or several symptoms.Pregnancy duration occur to be felt sick and to be desired to tell or slightly vomiting, anorexia, refreshing tired weak or with slight palpitation, before the test, this crowd is observed continuously, record symptom and variation, be divided into two groups at random, experimental group and control group, experimental group are taken embodiment 5, A group raw material products obtained therefrom, and control group is taken other medicine.Using method is: take 3-2 every day, takes each 3-9g after meal or between two meal and before sleeping.Every day, consumption was 27-9g; With one month was a course of treatment.Curative effect situation criterion: cure: take course of treatment of this product, hemochrome 〉=12, malaise symptoms disappears, and energy and muscle power obviously strengthen; Effectively: take course of treatment of this product, hemochrome content 〉=12, malaise symptoms alleviates or part disappears, and energy and muscle power strengthen; Invalid: as to take course of treatment of this product, malaise symptoms no change.The result is as shown in table 1.
Table 1: take embodiment 5, A group raw produce pregnant woman crowd treatment results
Figure BSA00000275313600061
Result of treatment: cure 26 examples (56.5%), effective 18 examples (39%), invalid 2 examples (1%), total effective rate 95.6%.
Effect obviously is better than control group, and self-induction symptom and muscle power spirit thereof change as shown in table 2 during taking.
Table 2: take embodiment 5 products sub-health state crowd process result of variations more than 60 years old
Figure BSA00000275313600062
The used prescription of the present invention, Colla Corii Asini nourishing blood enriching yin, nourishing blood and preventing abortion, in Chinese yam strengthening spleen and nourishing stomach, the beneficial gas peace, Poria cocos, dried orange peel are regulated the flow of vital energy, strengthening the spleen and stomach, antitoxic heart-soothing and sedative, fructus amomi, Buddha's hand, Caulis Perillae are amusing and stomach, regulate the flow of vital energy and remove to expand, Fructus Hordei Germinatus (stir-fry), hawthorn (life) reinforcing spleen to promote digestion, date and in, strengthening the spleen and stomach is arranged behind the compatibility, regulate the flow of vital energy help digestion, the effect of nourishing blood and tranquilization.
Took 10 days, feeling more than 22% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Took 20 days, feeling more than 57% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Took 30 days, feeling more than 96% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen.
Test example 2 pregnant insomnias
The surnamed Zhang patient, woman, 28 years old, gestation 3 months, insomnia and dreamful sleep is easily waken up, and confusing in the heart uneasiness after waking up is tired weak with body, sallow complexion, the time dizziness, pink tongue arranged, tongue is thin white, and arteries and veins is profound thin, and original meaning is not taken traditional Chinese herbal decoction. with embodiment 2, B group raw material is (with arillus longan 10g, spina date seed 15g, lily 3g) the containing donkey-hide gelatin piece of making, contain clothes, each one (3g), one day 3 times, one after each meal, add one piece, medication 10 day before the sleep evening, insomnia and dreamful sleep is easily waken up and is alleviated, and confusingly in the heart also alleviates, and the amount of receiving increases, spirit can, took 1 month, symptom is eliminated, sleep night and pacify, vexed removing, strength increases, receive the food can, continue clothes 2 months, discomfort does not appear when the patient takes.
The test example is weak 3 postpartum
Postpartum shortness of breath and fatigue, dizziness, sallow complexion, fatiguability, palpitaition, underbelly has a dull ache or lochiorrhagia, tongue is light, tongue is thin white, weak pulse or thin and unable.One of them or several symptoms are arranged.Containing of the puerpera's special use ass hide gelatin preparation that clothes embodiment 3, B group raw material is made, each one (3g) one day 3 times, takes after meal or between two meal, Time of Administration 1~5 month, have 28 puerperas and take, take the back symptom and eliminate 20 examples, sx 6 examples, invalid 2 examples, total effective rate 92.86% in the use and after taking, is not seen significant discomfort.
In embodiment 3, the B prescription, sealwort, Chinese yam, radix pseudostellariae, strengthening the spleen and replenishing qi; Donkey-hide gelatin, Radix Angelicae Sinensis, peach kernel, black fungus are tonified the blood and arrest bleeding, blood-activating analgetic; Poria cocos, dried orange peel, fructus amomi, date, strengthening the spleen and stomach is regulated the flow of vital energy; Rhizoma zingiberis, pain relieving in the temperature; All medicine mutually 5, can strengthening the spleen and replenishing qi, tonify the blood and arrest bleeding, pain relieving in the temperature, can be used for diseases such as deficiency of qi and blood in postpartum, lochiorrhagia.

Claims (10)

1. the preparation method of containing of pregnant and lying-in women's special use donkey-hide gelatin is characterized in that step is as follows:
(1) donkey-hide gelatin is dissolved in the functional mass extract, the consumption of donkey-hide gelatin is 1~10% of a functional mass extract weight;
(2) (1) gained material is put outgased in the mould;
℃ (3)-15----80 ℃ are freezing 2~24 hours;
(4) vacuum freeze drying, cutting, packing gets final product.
2. the described preparation method of claim 1 is characterized in that, described functional mass extract is that following raw material adds water 1500-2200 part, decocts 20-45 minute, and filtrate concentrates and gets; When the maternity dress time spent, get A group raw material; When the maternity clothing time spent, get B group raw material, be weight portion:
A group: Chinese yam 15-25 part, Poria cocos 8-15 part, fructus amomi 4-8 part, Buddha's hand 2-5 part, Caulis Perillae 4-8 part, Fructus Hordei Germinatus 2-6 part, hawthorn 2-5 part, date 15-25 part, dried orange peel 2-5 part;
B group: sealwort 15-25 part, Chinese yam 25-35 part, Radix Angelicae Sinensis 8-12 part, radix pseudostellariae 8-14 part, black fungus 8-12 part, peach kernel 8-12 part, Poria cocos 8-12 part, dried orange peel 8-10 part, fructus amomi 6-10 part, rhizoma zingiberis 2-5 part, date 15-25 part.
3. the described preparation method of claim 2 is characterized in that, the raw material that described A, B are two groups is respectively:
A group: Chinese yam 16-22 part, Poria cocos 10-12 part, fructus amomi 5-6 part, Buddha's hand 3-4 part, Caulis Perillae 5-7 part, Fructus Hordei Germinatus 3-5 part, hawthorn 3-4 part, date 18-20 part, dried orange peel 3-4 part;
B group: sealwort 18-20 part, Chinese yam 25-30 part, Radix Angelicae Sinensis 9-10 part, radix pseudostellariae 10-12 part, black fungus 9-10 part, peach kernel 9-10 part, Poria cocos 9-10 part, dried orange peel 9-10 part, fructus amomi 6-8 part, rhizoma zingiberis 2-3 part, date 18-20 part.
4. the described preparation method of claim 2 is characterized in that, the raw material that A, B are two groups is respectively:
A group: 20 parts of Chinese yams, 10 parts in Poria cocos, 6 parts of fructus amomis, 3 parts of Buddha's hands, 6 parts of Caulis Perillaes, 3 parts in Fructus Hordei Germinatus, 3 parts of hawthorn, 20 parts in date, 4 parts of dried orange peels;
B group: 20 parts of sealworts, 30 parts of Chinese yams, 10 parts of Radix Angelicae Sinensis, 10 parts of radix pseudostellariaes, 10 parts of black fungus, 10 parts in peach kernel, 10 parts in Poria cocos, 10 parts of dried orange peels, 6 parts of fructus amomis, 3 parts of rhizoma zingiberis, 20 parts in date.
5. the arbitrary described preparation method of claim 1-4 is characterized in that, the consumption of donkey-hide gelatin is 3~7% of a functional mass extract weight in the step (1).
6. the arbitrary described preparation method of claim 1-4 is characterized in that, step (3) cryogenic temperature is-30 ℃----60 ℃, cooling time is 12-20 hour.
7. the described preparation method of claim 6 is characterized in that, cryogenic temperature is-40 ℃----50 ℃, cooling time is 15-18 hour.
8. the arbitrary described preparation method of claim 1-4 is characterized in that, also adds an amount of sweet substance in step (1) gained material.
9. the described preparation method of claim 8 is characterized in that, described sweet substance is a kind of in sucrose, fructose, honey, oligoisomaltose, soyabean oligosaccharides, the hydroxyl isomaltulose or several.
10. the arbitrary described preparation method of claim 1-4 is characterized in that, also adds an amount of black sesame powder and/or walnut meat powder in step (1) gained material.
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CN102511866A (en) * 2011-12-29 2012-06-27 山西汉波食品股份有限公司 Red jujube donkey-hide gelatin thick syrup and production technology thereof
CN102813194A (en) * 2012-08-03 2012-12-12 辽宁富东制药有限公司 Blood-replenishing and beautifying paste and preparation method of blood-replenishing and beautifying paste
CN102919825A (en) * 2011-08-10 2013-02-13 山东东阿阿胶股份有限公司 Donkey-hide gelatin paste for heart fire clearing, and its preparation method
CN104206952A (en) * 2014-08-13 2014-12-17 山东东阿阿胶股份有限公司 Female pregestational conditioning donkey-hide gelatin cake and making method thereof
CN105079691A (en) * 2015-08-28 2015-11-25 广东伊茗药业有限公司 Donkey-hide gelatin and preparing method thereof
CN107752000A (en) * 2017-10-12 2018-03-06 山东岐伯堂生物科技有限公司 A kind of colla corii asini cake preparation method for postpartum recuperating

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Cited By (7)

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CN102919825A (en) * 2011-08-10 2013-02-13 山东东阿阿胶股份有限公司 Donkey-hide gelatin paste for heart fire clearing, and its preparation method
CN102919825B (en) * 2011-08-10 2014-04-16 山东东阿阿胶股份有限公司 Donkey-hide gelatin paste for heart fire clearing, and its preparation method
CN102511866A (en) * 2011-12-29 2012-06-27 山西汉波食品股份有限公司 Red jujube donkey-hide gelatin thick syrup and production technology thereof
CN102813194A (en) * 2012-08-03 2012-12-12 辽宁富东制药有限公司 Blood-replenishing and beautifying paste and preparation method of blood-replenishing and beautifying paste
CN104206952A (en) * 2014-08-13 2014-12-17 山东东阿阿胶股份有限公司 Female pregestational conditioning donkey-hide gelatin cake and making method thereof
CN105079691A (en) * 2015-08-28 2015-11-25 广东伊茗药业有限公司 Donkey-hide gelatin and preparing method thereof
CN107752000A (en) * 2017-10-12 2018-03-06 山东岐伯堂生物科技有限公司 A kind of colla corii asini cake preparation method for postpartum recuperating

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