CN101828981A - Helical scaffold consisting of streamline sectional filaments - Google Patents

Helical scaffold consisting of streamline sectional filaments Download PDF

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Publication number
CN101828981A
CN101828981A CN 201010164474 CN201010164474A CN101828981A CN 101828981 A CN101828981 A CN 101828981A CN 201010164474 CN201010164474 CN 201010164474 CN 201010164474 A CN201010164474 A CN 201010164474A CN 101828981 A CN101828981 A CN 101828981A
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China
Prior art keywords
scaffold
streamline
helical
equal
blood vessel
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Pending
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CN 201010164474
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Chinese (zh)
Inventor
陈增胜
邓小燕
樊瑜波
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Beihang University
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Beihang University
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Priority to CN 201010164474 priority Critical patent/CN101828981A/en
Publication of CN101828981A publication Critical patent/CN101828981A/en
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Abstract

The invention discloses a novel helical scaffold consisting of streamline sectional filaments, which is characterized in that a swept surface of the helical structure is streamline; and the streamline sectional structure is as an A part of figure 1 in the attached diagram of the instruction book and can be described by the following exponential curve function similar as normal distribution: R(z) is more than or equal to 0 and less than or equal to h, z is more than or equal to -2.5 and less than or equal to 2.5, z is equal to d/h, and e is 2.718281828459..., wherein h is the maximum height of the streamline scaffold, d is the thickness of the scaffold (namely the length of the area of the contact face of the scaffold and a blood vessel), D is the diameter of the scaffold placed into the blood vessel, e is the base of a natural logarithm, the streamline maximum height h is 1/20 to 1/10 diameter of the scaffold placed into the blood vessel, and the thickness d of the scaffold is 2.5 times h. The thread pitch of the helical structure is 2 to 10 millimeters, and the length is 1 to 2 centimeters. Compared with the traditional square or round section, the special streamline section forming the scaffold filaments can greatly reduce the disturbance of the embedded scaffold on the blood and fulfill the purpose of effectively preventing restenosis after the scaffold is placed into the blood vessel, so the helical scaffold has important clinical application value.

Description

The helical mount that a kind of streamline section filament is formed
Technical field
The present invention relates to a kind of cardiovascular intervention apparatus, more particularly, is a kind of novel helical mount of being made up of the streamline section filament.
Background technology
Inserting endovascular stent in the blood vessel of narrow or obstruction is to be used for one of important method for the treatment of cardiovascular disease at present, and still, the restenosis problem after endovascular stent is implanted does not obtain at present fully and solves.A large amount of Hemodynamics Study show that regional flow's disturbance and flow field are one of major reason that causes restenosis unusually near the support that support is caused after implanting.Tradition is inserted generally being made up of the filament of square or circular cross-section of intravascular stent of human body, says that from hemodynamic angle the filament of this cross sectional shape draws near the mobile moving the support easily, thereby causes the generation of restenosis.If the circular or quadrate cross section of this conventional stent filament can be improved, its disturbance to blood flow is reduced, so just can from the hemodynamics angle solve insert behind the support in narrow problem.
Summary of the invention
The objective of the invention is at the restenosis problem after the present endovascular stent implantation, designed a kind of helical mount of forming by the streamline section filament, this support is compared with the support that traditional circular or square filament is formed, has the advantage on the hemodynamics, it is not easy to cause near the blood flow disturbance the support, thereby can reduce to insert the generation probability of restenosis behind the support.Certainly the streamline section of forming this helical mount also can apply to the support of other shapes except that spiral-shaped.
Concrete scheme of the present invention is a kind of helical mount of being made up of the streamline section filament.The A part of Fig. 1 in concrete graphic structure of the streamline section of this stent filaments such as the Figure of description, and can describe by the curvilinear function of following this similar normal distribution:
R ( z ) = he - z 2
0≤R(z)≤h,
Figure GSA00000105811400012
-2.5≤z≤2.5,z=d/h,e=2.718281828459...
Wherein h is the maximum height of this streamline support, and d is the thickness (being the length in the zone of support and blood vessel contact surface) of support, and D is the diameter of the support blood vessel of inserting, and e is the truth of a matter of natural logrithm
Adopt such scheme to reduce owing to insert near the blood flow disturbance of support that support itself is produced, and then reach following useful effect: reduce even eliminate to rise near the blood flow disturbance insert the stent filaments, improve near the boundary shear stress in the flow-disturbing zone stent filaments.
Description of drawings
Fig. 1 is structural representation of the present invention and the streamline section figure that forms stent filaments
Among Fig. 1: A partly is an enlarged diagram of forming the streamline section of stent filaments, B part structural representation of the present invention
The specific embodiment
Below in conjunction with the accompanying drawing and the specific embodiment the present invention is described in further detail:
As shown in Figure 1: the present invention is made up of single helical structure.The swept surface of this helical structure is new streamlined, and the curvilinear function of the similar normal distribution of this streamlined use is described,
Figure GSA00000105811400021
Figure GSA00000105811400022
Concrete parameter declaration sees top summary of the invention part for details.This fairshaped highest point h is 1/20th to 1/10th of a support implantation place blood vessel diameter, and backing thickness d (being the length in the zone of support and blood vessel contact surface) is 2.5 times of h.The pitch of helical structure is 2 millimeters to 10 millimeters, and length is 1-2 centimetre.In general clinical application, people can put into this support narrow or the artery-clogging place by guide wire, owing to form the filament special streamline of this support, traditional relatively square-section and circular cross-section, this support can reduce the disturbance of inserting behind the support blood flow greatly.Be exactly particularly relatively conventional stent improve the mobile shearing force in flow-disturbing zone behind the support, reduce the oscillatory shear power in flow disturbance zone, thereby make blood flow better wash away flow-disturbing zone behind the support, prevent the turbulent flow area area depositions of harmful substance behind support such as lipid, reach the purpose of restenosis behind effective prevention implantable intravascular support, therefore have important clinical application value.

Claims (5)

1. a new helical mount that is made of the streamline section filament is characterized in that the swept surface of described helical mount structure is streamlined and is single spiral.
2. a kind of new helical mount that constitutes by the streamline section filament according to claim 1, it is characterized in that, the swept surface of this helical mount structure is streamlined, this streamlined be a kind of curve of exponential function of similar normal distribution, in patent specification, have concrete formula and picture to describe.
3. a kind of new helical mount that is made of the streamline section filament according to claim 1 is characterized in that the highest point h of the streamlined swept surface of this helical mount is 1/20th to 1/10th of a support implantation place blood vessel diameter.
4. a kind of new helical mount that is made of the streamline section filament according to claim 1 is characterized in that, the pitch of the helical structure support of being made up of the streamline section filament is 2 millimeters to 10 millimeters.
5. a kind of new helical mount that is made of the streamline section filament according to claim 1 is characterized in that, the length of the helical structure support of being made up of the streamline section filament is 1 to 2 centimetre.
CN 201010164474 2010-04-29 2010-04-29 Helical scaffold consisting of streamline sectional filaments Pending CN101828981A (en)

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CN 201010164474 CN101828981A (en) 2010-04-29 2010-04-29 Helical scaffold consisting of streamline sectional filaments

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105520793A (en) * 2016-03-08 2016-04-27 殷月慧 Push rod type vascular dilator implanting tool
CN105796155A (en) * 2016-03-08 2016-07-27 侯伟娜 Spiral clamping-type vessel dilator assembly
CN115844605A (en) * 2023-02-17 2023-03-28 太原理工大学 Artery blood vessel support

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0799607A2 (en) * 1996-04-01 1997-10-08 Medtronic, Inc. Intravascular stent having flattened profile
US7169187B2 (en) * 1999-12-22 2007-01-30 Ethicon, Inc. Biodegradable stent
CN1970097A (en) * 2005-05-24 2007-05-30 北京奥精医药科技有限公司 Composite stent material, composite stent and production method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0799607A2 (en) * 1996-04-01 1997-10-08 Medtronic, Inc. Intravascular stent having flattened profile
US7169187B2 (en) * 1999-12-22 2007-01-30 Ethicon, Inc. Biodegradable stent
CN1970097A (en) * 2005-05-24 2007-05-30 北京奥精医药科技有限公司 Composite stent material, composite stent and production method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105520793A (en) * 2016-03-08 2016-04-27 殷月慧 Push rod type vascular dilator implanting tool
CN105796155A (en) * 2016-03-08 2016-07-27 侯伟娜 Spiral clamping-type vessel dilator assembly
CN105796155B (en) * 2016-03-08 2018-03-06 青岛市市立医院 The clipping vessel dilator assembly of spiral
CN115844605A (en) * 2023-02-17 2023-03-28 太原理工大学 Artery blood vessel support
CN115844605B (en) * 2023-02-17 2023-05-16 太原理工大学 Arterial vessel stent

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Open date: 20100915