CN101810720A - Skin disease external powder for comprehensively killing and inhibiting bacteria and diminishing inflammation and using method thereof to beriberi skin disease - Google Patents

Skin disease external powder for comprehensively killing and inhibiting bacteria and diminishing inflammation and using method thereof to beriberi skin disease Download PDF

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Publication number
CN101810720A
CN101810720A CN 201010162905 CN201010162905A CN101810720A CN 101810720 A CN101810720 A CN 101810720A CN 201010162905 CN201010162905 CN 201010162905 CN 201010162905 A CN201010162905 A CN 201010162905A CN 101810720 A CN101810720 A CN 101810720A
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skin disease
parts
inhibiting bacteria
diminishing inflammation
powder
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徐金刚
蒋益如
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Abstract

The invention discloses a skin disease external powder for comprehensively killing and inhibiting bacteria and diminishing inflammation, which comprises the following raw materials in part by weight: 10 to 100 parts of talcpowder, 1 to 20 parts of metronidazole, 1 to 10 parts of phellodendron, 1 to 10 parts of borneol, 1 to 10 parts of menthol, 1 to 10 parts of griseofulvin, 1 to 5 parts of chloramphenicol, 1 to 5 parts of sulfamethoxazole, 1 to 5 parts of aspirin, 1 to 5 parts of alum, 1 to 3 parts of chlortrimeton and 1 to 3 parts of vitamin B1. The invention also relates to a using method of the skin disease external powder for comprehensively killing and inhibiting bacteria and diminishing inflammation to beriberi skin disease. The medicaments are effectively combined, and the effects of the medicaments are supported one another, so the skin disease external powder has the effects of comprehensively killing poison, killing and inhibiting bacteria, diminishing inflammation, relieving itching, killing pain, clearing away heat, releasing toxin, restraining sweat gland, removing sweat and deodorizing on an affected part, and simultaneously has effects of killing and inhibiting bacteria and disinfecting on the environment of the affected part so as to fulfill the aims of radically curing fungi and bacterial infection skin disease and restoring the skin.

Description

A kind of skin disease external powder of comprehensively killing inhibiting bacteria and diminishing inflammation and the using method on beriberi skin disease thereof
Technical field
The invention belongs to medical technical field, be specifically related to a kind of have comprehensive sterilization, antibacterial, antiinflammatory, antipruritic, analgesia function, can treat dermopathic external-applied medicinal powder, and relate to the using method of this medicated powder on beriberi type dermatosis.
Background technology
Usually bring misery by fungus, germ various scytitiss, prurituss such as tinea bacterium, escherichia coli, mycete and antibacterials to the patient, and easily recurrence.Modal is the beriberi skin disease of fungal infection, and infectiousness is strong, sickness rate is high and the intractable that has easy recurrence, be difficult to effect a radical cure, has brought great inconvenience for people's live and work.If untimely treatment, dermatosiss such as beriberi also can cause tissue infection symptoms such as erysipelas, tinea.
The Chinese and western drugs for the treatment of fungal infection and antiinflammatory in the market is a lot, but find that the easily recurrence of treatment back is generally arranged, do not possess comprehensively killing, the function of antibacterial, antiinflammatory, thereby can not eradicate this type of dermopathic intractable; Wherein most of external used medicine is liquid and paste, and this medicine directly acts on focus, but can not play the defective of comprehensively killing to environment that focus contacted such as beriberi person's shoes; Perhaps be powdered drug, need the dissolving back to soak and smear, or prevent from skin damage is directly acted on environment; Perhaps be endo-medicine, but the defective that pair the intestines and stomach stimulates, side effect is big, efficient is low, can not directly act on focus is arranged equally; Moreover this type of medicine dozens of yuan, unit up to a hundred easily, cost an arm and a leg.
I am through patent retrieval, find in the known public technology, there are 3 pieces of patent ZL200610021018.5, ZL200610128305.6 and ZL200610051068.8 and the present invention similar about germ-resistant external-applied medicinal powder, be all powdered drug, but only still have limitation, different with Therapeutic Method at treating beri-beri.Wherein, what ZL200610021018.5 introduced is " athlete foot powder and preparation method thereof ", it selects the material of compositions is Chinese medicine, concerning the ordinary people, exist hard to tell whether it is true or false, do not have production safety licence, producer's information, price is opaque and the skimble-scamble problem of standard, simultaneously its using method is to carry out the foot bath treatment after medicated powder is converted water; What ZL200610128305.6 introduced is " the beriberic medicated powder of a kind of treatment ", though its material therefor is cheap, but according to patent require to calculate one the course of treatment required raw material be: metronidazole specification 0.5g/ sheet needs 60-100 sheet, vitamin B1 specification 25mg/ sheet to need 1200-2000 sheet, chlorphenamine specification 10mg/ sheet to need the 1500-2500 sheet, boric acid 80-120g, so a preparation dosage course of treatment is great, and it is expensive, Therapeutic Method is to place sterilization in the footwear simultaneously, does not directly act on focus; What ZL200610051068.8 introduced is " the smelly feet powder that places footwear internal therapy foot odor " equally, there is the same defective of ZL200610128305.6 equally, and have that component is too simple, the pharmacology limitation, acetyl aminophenol and caffeine defective on the high side and that be difficult to buy in general pharmacy.Can carry out comprehensive bactericidal at affected part and affected part environment simultaneously so the described medicated powder of above patent is neither.
So do not have in known technology that preparation is simple, the pharmacology collocation rationally, low price, raw materials market be general, the technology enlightenment of the skin disease external powder that can carry out the comprehensively killing inhibiting bacteria and diminishing inflammation at the environment that the affected part is contacted with the affected part simultaneously, and in the practical application, the medicated powder that has similar effect really with and can effect a radical cure the dermopathic market demands such as beriberi.
Summary of the invention
The object of the present invention is to provide a kind of cheap, go for the external-applied medicinal powder that the simple preparation of ordinary people and production line are produced in enormous quantities, this medicated powder has the function of comprehensive sterilization, antibacterial, antiinflammatory, antipruritic, analgesia, treatment to the skin that infects, simultaneously the environment with contact skin had sterilization, antibacterial, disinfectant effect, and easy to use, have no side effect.
Technical scheme of the present invention is: a kind of skin disease external powder of comprehensively killing inhibiting bacteria and diminishing inflammation comprises the raw material of following parts by weight: Pulvis Talci 10-100 part, metronidazole 1-20 part, Cortex Phellodendri 1-10 part, Borneolum Syntheticum 1-10 part, Mentholum 1-10 part, griseofulvin 1-10 part, chloromycetin 1-5 part, sulfamethoxazole 1-5 part, aspirin 1-5 part, Alumen 1-5 part, chlorphenamine 1-3 part, vitamin B 11-3 part.
In a preferred embodiment of the present invention, the skin disease external powder of described comprehensively killing inhibiting bacteria and diminishing inflammation comprises that also parts by weight are not more than 1 part nanometer silver powder.
Another object of the present invention is to provide the using method of skin disease external powder on beriberi skin disease of comprehensively killing inhibiting bacteria and diminishing inflammation, by the use of skin disease external powder on the beriberi skin disease problem of comprehensively killing inhibiting bacteria and diminishing inflammation, can find out the present invention can be effective to cure comprehensively, simply, fast sweaty foot too much, foot odor, foot pruritus, foot get blister, beriberi skin diseases such as foot rots, suppuration, swelling of the feet pain.
The using method of a kind of skin disease external powder of comprehensively killing inhibiting bacteria and diminishing inflammation on beriberi skin disease:
To comprise meter by weight: Pulvis Talci 10-100 part, metronidazole 1-20 part, Cortex Phellodendri 1-10 part, Borneolum Syntheticum 1-10 part, Mentholum 1-10 part, griseofulvin 1-10 part, chloromycetin 1-5 part, sulfamethoxazole 1-5 part, aspirin 1-5 part, Alumen 1-5 part, chlorphenamine 1-3 part, vitamin B 1The skin disease external powder of the comprehensively killing inhibiting bacteria and diminishing inflammation of 1-3 part grinds and stirs, before the sleep, foot is cleaned, be coated with uniformly with 1-10g medicated powder and be sprinkled upon affected part one deck with warm water, put on socks, sleeping then, wear the preceding sleeping preceding step in evening that repeats of footwear the next morning, 3-10g medicated powder evenly is sprinkled upon in two footwear to be worn respectively again, put on footwear then, every day, each once continuous use 7-10 days, got final product sooner or later.
The present invention is directed to the using method on the beriberi skin disease, the skin disease external powder that has disclosed the comprehensively killing inhibiting bacteria and diminishing inflammation to the affected part sterilize, antibacterial, anti-inflammatory treatment the time, to the environment that the affected part contacted also sterilize simultaneously, antibacterial, the sterilization, do not have virus, fungus to exist thereby reach the environment of curing back former affected part contact, avoid causing once more and infect and the situation of state of an illness bounce-back occurs.Characteristics easy to use, easy to clean, that have no side effect, preserve easily that the present invention simultaneously has, and have the acceleration therapeutic process, the state of getting well fast, thus the patient suffering thoroughly solved.。
The specific embodiment
Below preferred embodiment of the present invention is described in detail, thereby protection scope of the present invention is made more explicit defining so that advantages and features of the invention can be easier to be it will be appreciated by those skilled in the art that.
The specific embodiment
Embodiment 1:
Following table is the prescription of the comprehensively killing inhibiting bacteria and diminishing inflammation medicated powder of formation embodiments of the invention 1:
Material name Parts by weight
Pulvis Talci ??10
Metronidazole ??1
Cortex Phellodendri ??1
Borneolum Syntheticum ??1
Mentholum ??1
Griseofulvin ??1
Chloromycetin ??1
Sulfamethoxazole ??1
Aspirin ??1
Alumen ??1
Chlorphenamine ??1
Vitamin B 1 ??1
Nanometer silver powder ??0.1
Embodiment 2:
Following table is the prescription of embodiments of the invention 2:
Material name Parts by weight
Pulvis Talci ??55
Metronidazole ??10
Cortex Phellodendri ??5
Borneolum Syntheticum ??4
Mentholum ??5
Griseofulvin ??4.5
Chloromycetin ??2.5
Sulfamethoxazole ??2.5
Aspirin ??2.5
Alumen ??2.5
Material name Parts by weight
Chlorphenamine ??1.5
Vitamin B 1 ??1.5
Nanometer silver powder ??0.5
Embodiment 3:
Following table is the prescription of embodiments of the invention 3:
Material name Parts by weight
Pulvis Talci ??100
Metronidazole ??20
Cortex Phellodendri ??10
Borneolum Syntheticum ??10
Mentholum ??10
Griseofulvin ??10
Chloromycetin ??5
Sulfamethoxazole ??5
Aspirin ??5
Alumen ??5
Chlorphenamine ??3
Vitamin B 1 ??3
Nanometer silver powder ??1
Embodiment 4:
Following table is the prescription of embodiments of the invention 4:
Material name Parts by weight
Pulvis Talci ??90
Metronidazole ??8
Cortex Phellodendri ??8
Borneolum Syntheticum ??4
Mentholum ??6.5
Griseofulvin ??4
Chloromycetin ??1
Sulfamethoxazole ??4
Aspirin ??3
Alumen ??1
Chlorphenamine ??2
Vitamin B 1 ??2.5
Nanometer silver powder ??0.3
Embodiment 5:
Following table is the prescription of embodiments of the invention 5:
Material name Parts by weight
Pulvis Talci ??45
Metronidazole ??12
Cortex Phellodendri ??7
Borneolum Syntheticum ??6
Mentholum ??3
Griseofulvin ??9
Material name Parts by weight
Chloromycetin ??2
Sulfamethoxazole ??4
Aspirin ??4.2
Alumen ??1.5
Chlorphenamine ??3
Vitamin B 1 ??1.5
Nanometer silver powder ??0.01
Mentioned nanometer silver powder is the antibacterial nano silver powder of AGP-P010 strong effect wide-spectrum that antimicrobial nano argentum powder preferably uses to be provided by the positive nanosecond science and technology in Chinese Shanghai Shanghai company in the foregoing description.Studies show that the nanometer silver particle diameter mostly about 25 nanometers, all has intensive inhibition and killing action to tens of kinds of pathogenic microorganism such as escherichia coli, gonococcus, chlamydia trachomatiss, and can not produce drug resistance.Animal experiment shows that this nanometer silver antimicrobial micropowder is several thousand times that use amount reaches standard dose, and animal subject does not have poisoning manifestations yet.Simultaneously, it also has the promotion repair to impaired epithelial cell.What deserves to be mentioned is that this product is met the water antibacterial effect and more strengthened, and is more conducive to treatment of diseases.
Pulvis Talci mentioned in the foregoing description is the commercially available prod, has lubricity, clearing away summer-heat, and skin ulcer, external treatment eczema, eczema, the effect of miliaria are held back in damp eliminating; Metronidazole is the commercially available prod, has wide spectrum anaerobe resistant and protozoacidal effect, and antagonism clostridium tetani and helicobacter pylori activity are obvious, have the effect of anti-inflammatory analgetic simultaneously concurrently; Cortex Phellodendri is the commercially available prod, has effects such as antibiotic, antifungal, anti-trichomonal, anti-hepatitis, antiulcer; Borneolum Syntheticum is the commercially available prod, be used for not holding back after skin infection swells and ache, bursts, clearing away heat to alleviate pain curative effect preferably arranged; Mentholum is the commercially available prod, the main chafe mucosa of function, and at antipruritic, antiinflammatory, analgesic simultaneously, the part has cool sense, the clinical pain that is used for, inflammation and swelling; Mainly there are well antibiotic, bactericidal action in my commercially available prod of griseofulvin tablet to superficial mycosis class tinea bacterium such as trichophyta, sporidiole bacteria, epidermophytons; Chloromycetin is the commercially available prod, is broad-spectrum antibacterial agent, and is comparatively effective to escherichia coli etc.; Sulfamethoxazole is the commercially available prod, is a kind of broad ectrum antibiotic, is mainly used in sensitive organism and causes local soft tissue or traumatic infection etc.; Aspirin is the commercially available prod, has the effect of analgesia, antiinflammatory; Alumen is the commercially available prod, has stronger astriction, and the traditional Chinese medical science thinks that Alumen has the detoxifcation parasite killing, and is quick-fried wet antipruritic, hemostasis antidiarrheal, the effect of heat clearing away expectorant, in recent years studies confirm that Alumen also has effects such as antibiotic, anti-trichomonas vaginitis; Chlorphenamine is the commercially available prod, is a kind of antiallergic medicine commonly used, has the toxic and side effects that prevents that inappropriate medication from causing, the effect that suppresses antibacterial is arranged; Vitamin B1 is used for because of Vitamin B1 deficiency causes many multiple neural inflammation, as the treatment of beriberi pathogenic bacteria.Effective combination of said medicine, function is supported each other, to reach comprehensive virus killing, sterilization, antibacterial, antiinflammatory, antipruritic, analgesia, heat clearing away, detoxifcation, convergence sweat gland, go antiperspirant, deodorization, subside a swelling, go fungus bacterial infection class dermatosiss such as bubble, suppuration, hemostatic effect and treatment beriberi (tinea pedis), the tinea manuum, tinea capitis, tinea cruris, eczema, rehabilitation skin makes skin obtain the purpose of newborn glabrous skin.
The component of arbitrary embodiment of the foregoing description 1-5 is mixed, through grind and dispersed with stirring evenly after, obtain placing the container of sealing to get final product then as skin disease external powder with comprehensively killing inhibiting bacteria and diminishing inflammation, the time spent seals not In Shade.
Being coated with of skin disease external powder by the resulting comprehensively killing inhibiting bacteria and diminishing inflammation of the foregoing description 1-5 is sprinkled upon in the environment that contacts with the skin affected part on the skin of suffering from fungal infection, through clinical reality, general medication promptly showed no significant discomfort sensation in 4 days or symptom is obviously improved or partial symptoms is eliminated, the alleviation of particularly aching, itch, symptom is eliminated after 7-10 days, no longer recurrence in 5 years.
Application examples 1:
The skin disease external powder of the resulting comprehensively killing inhibiting bacteria and diminishing inflammation of arbitrary embodiment of the foregoing description 1-5 is used at beriberi skin disease, specifically: before the sleep, with warm water foot is cleaned, be coated with uniformly with 1-10g medicated powder and be sprinkled upon affected part one deck, put on socks, sleeping then, repeat sleeping preceding step in evening before wearing footwear the next morning, 3-10g medicated powder evenly is sprinkled upon in two footwear to be worn respectively again, put on footwear then, sooner or later each once can take effect, generally can cure in medication 7-10 days for 4-5 time every day.
Application examples 2:
For tinea manuum class dermatosis patient, to hand-wash only with warm water, be coated with uniformly with 1-10g medicated powder and be sprinkled upon affected part one deck, it is sleeping to put on one's gloves then, repeat sleeping preceding step in evening after getting up the next morning, 3-10g medicated powder evenly is sprinkled upon respectively in the glove to be worn again, every day sooner or later respectively once, can take effect for 4-5 time, can cure in general medication 7-10 days.
Application examples 3:
For tinea capitis class patient, with warm water head is cleaned and to be dried, be coated with uniformly with 1-10g medicated powder and be sprinkled upon affected part one deck, it is sleeping to put on headgear or medicated cap then, repeat sleeping preceding step in evening after getting up the next morning, 3-10g medicated powder evenly is sprinkled upon respectively in the medicated cap to be worn again, every day sooner or later respectively once, can take effect for 4-5 time, can cure in general medication 7-10 days.
Application examples 4:
For eczema patients, with warm water the affected part is cleaned and to be dried, be coated with uniformly with 1-10g medicated powder and be sprinkled upon affected part one deck, gauze is sleeping after wrapping up in and applying then, the step of evening before sleeping repeated in the back of getting up the next morning, 3-10g medicated powder evenly is sprinkled upon respectively on the medicated clothing that the eczema affected part contacted again, and every day, each was once sooner or later, can take effect for 4-5 time, can cure in general medication 10-15 days.
From above-mentioned example as can be seen, the present invention is by the application of skin disease external powder on dermatosis of comprehensively killing inhibiting bacteria and diminishing inflammation, and curative effect of medication of the present invention as can be seen is remarkable.Its pharmacological research proves, dermatosis generally is by fungus, antibacterial, skin infection disease and allergic dermatitis that virus etc. cause, and the organic assembling of medicine of the present invention, sterilization, antibacterial class medicine, antiinflammatory, the anti-inflammatory type medicine, antipruritic analgesic drug, antipyretic and antidotal type, antiallergic class medicine, vitamins, in, west class medicine etc. is supported mutually, medicated powder dissolves in the illing skin top layer, play virus killing, sterilization, antibacterial, antiinflammatory, antipruritic, analgesia, heat clearing away, detoxifcation, the convergence sweat gland removes antiperspirant, deodorization, detumescence, remove bubble, suppurate, hemostasis, rehabilitation skin, make skin obtain newborn glabrous skin, surrounding to the affected part contact plays virus killing simultaneously, sterilization, the bacteriostatic effect, thereby reach quick treatment beriberi, the tinea manuum, tinea capitis, tinea cruris, dermatosis such as fungus bacterial infections such as eczema and the purpose of subinfection bounce-back no longer, prescription are simple and easy to, pharmacology, science is clear, meet clinical practice fully, have outstanding clinical meaning, therapeutic effect is good, and economy and social meaning are huge.
The above; it only is the specific embodiment of the present invention; but protection scope of the present invention is not limited thereto; any those of ordinary skill in the art are in the disclosed technical scope of the present invention; variation or the replacement that can expect without creative work all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain that claims were limited.

Claims (4)

1. the skin disease external powder of a comprehensively killing inhibiting bacteria and diminishing inflammation, it is characterized in that, comprise the raw material of following parts by weight: Pulvis Talci 10-100 part, metronidazole 1-20 part, Cortex Phellodendri 1-10 part, Borneolum Syntheticum 1-10 part, Mentholum 1-10 part, griseofulvin 1-10 part, chloromycetin 1-5 part, sulfamethoxazole 1-5 part, aspirin 1-5 part, Alumen 1-5 part, chlorphenamine 1-3 part, vitamin B 11-3 part.
2. the skin disease external powder of comprehensively killing inhibiting bacteria and diminishing inflammation according to claim 1 is characterized in that, the skin disease external powder of described comprehensively killing inhibiting bacteria and diminishing inflammation comprises that also parts by weight are not more than 1 part nanometer silver powder.
3. the using method of the skin disease external powder of a comprehensively killing inhibiting bacteria and diminishing inflammation on beriberi skin disease:
To comprise meter by weight: Pulvis Talci 10-100 part, metronidazole 1-20 part, Cortex Phellodendri 1-10 part, Borneolum Syntheticum 1-10 part, Mentholum 1-10 part, griseofulvin 1-10 part, chloromycetin 1-5 part, sulfamethoxazole 1-5 part, aspirin 1-5 part, Alumen 1-5 part, chlorphenamine 1-3 part, vitamin B 1The skin disease external powder of the comprehensively killing inhibiting bacteria and diminishing inflammation of 1-3 part grinds and stirs, before the sleep, foot is cleaned, be coated with uniformly with 1-10g medicated powder and be sprinkled upon affected part one deck with warm water, put on socks, sleeping then, wear the preceding sleeping preceding step in evening that repeats of footwear the next morning, 3-10g medicated powder evenly is sprinkled upon in two footwear to be worn respectively again, put on footwear then, every day, each once continuous use 7-10 days, got final product sooner or later.
4. the using method of the skin disease external powder of comprehensively killing inhibiting bacteria and diminishing inflammation according to claim 3 on beriberi skin disease, it is characterized in that, the skin disease external powder of described comprehensively killing inhibiting bacteria and diminishing inflammation to the affected part sterilize, antibacterial, anti-inflammatory treatment the time, to the environment that the affected part contacted also sterilize simultaneously, antibacterial, the sterilization, do not have virus, fungus to exist thereby reach the environment of curing back former affected part contact, avoid causing once more and infect and the situation of state of an illness bounce-back occurs.
CN 201010162905 2010-04-08 2010-04-08 Skin disease external powder for comprehensively killing and inhibiting bacteria and diminishing inflammation and using method thereof to beriberi skin disease Pending CN101810720A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104188986A (en) * 2014-09-18 2014-12-10 张好勇 Application of sulfa drug composition in preparation of medicine for treating foot odor
CN104436164A (en) * 2014-12-10 2015-03-25 唯美度科技(北京)有限公司 Foot powder containing biologic peptide composition, as well as preparation thereof
CN104606295A (en) * 2015-02-09 2015-05-13 程贵昌 Non-antibiotic antifungal externally used medicine
CN106109801A (en) * 2016-08-25 2016-11-16 胡文忠 A kind of treat burn, scald and the medicated powder of suppurative wound

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1883487A (en) * 2006-05-23 2006-12-27 彭传喜 Powder placed inside shoes for treating foot odor and beriberi
CN1969880A (en) * 2006-11-30 2007-05-30 左旭洋 Medicinal powder for treating beriberi

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1883487A (en) * 2006-05-23 2006-12-27 彭传喜 Powder placed inside shoes for treating foot odor and beriberi
CN1969880A (en) * 2006-11-30 2007-05-30 左旭洋 Medicinal powder for treating beriberi

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《山西医药杂志》 20051031 任素兰 复方脚气搽剂的制备及疗效分析 872-873 1-4 第34卷, 第10期 2 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104188986A (en) * 2014-09-18 2014-12-10 张好勇 Application of sulfa drug composition in preparation of medicine for treating foot odor
CN104436164A (en) * 2014-12-10 2015-03-25 唯美度科技(北京)有限公司 Foot powder containing biologic peptide composition, as well as preparation thereof
CN104606295A (en) * 2015-02-09 2015-05-13 程贵昌 Non-antibiotic antifungal externally used medicine
CN106109801A (en) * 2016-08-25 2016-11-16 胡文忠 A kind of treat burn, scald and the medicated powder of suppurative wound

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Open date: 20100825