CN101744897A - External medicine preparation for treating acute and chronic eczema - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating skin disease, in particular to an external medicine preparation for treating acute and chronic eczema. The preparation is prepared from liquorice, honeysuckle, lightyellow sophora root, alum, Chinese granesbill, borneol, radix astragali, rhubarb, dandelion and root of common peony proportioning by weight and prepared by extracting the components with water and concentrating. The formulation of the medicine preparation is scientific and rational. The clinical experiment shows that the medicine preparation takes effect fast; the treating period is short; and the healing rate is 98%. The effects of eliminating inflammation and stopping itching are good; and the irritation to skin is small. The preparation can radically treat the disease. The disease is hard to relapse after healed. The medicine preparation is capable of relieving the pain of patient and reducing the treating cost, and is a perfect medicine for patient.

Description

The external medicine preparation of treatment acute and chronic eczema

Technical field

The present invention relates to the dermopathic Chinese medicine of a kind of treatment, particularly a kind of external medicine preparation for the treatment of acute and chronic eczema.Be acute and chronic eczema patient's first-selected curative, the person uses also to be suitable for the skin pruritus.

Background technology

Eczema is the anaphylactic disease that a kind of internal and external factor causes, also is the more common a kind of dermatosis of stage of incubation and allergic constitution.The cause of disease of eczema is many-sided, exopathogenic factor such as climate change, living environment, day photostimulation, animal skin and pollen etc.; The fluctuation of being in a bad mood, psychentonia, insomnia and endocrine disturbance that its endogenous cause of ill is common or infection focus etc. are all multifactor, all bring out eczema easily.Acute eczema is usually expressed as the pimple or the papulovesicle of the intensive foxtail millet grain size of pleomorphism, phlysis appears when serious, the basilar part flushing is very itched, the back skin lesion of scratching is sepage, rotten to the corn shape, as treat and untimelyly often formed pustule, pus and pus crusts again by bacterial infection, regional glandular enlargement, universal eczema is with General Symptomies such as heatings.Common in the past therapeutic modality is an external Bufexamac ointment, antiallergic class medicine for oral administration.Although this therapeutic modality has certain curative effect and good effect, but also exist the slow course of treatment that takes effect long, the undesirable cure rate of the effect that has is low, shows effect repeatedly and causes forming chronic inflammatory disease, become chronic eczema, pars affecta skin thickens, and rough surface is lichenification, go up attached squama, incrustation, infringement mostly is limitation, clear-cut margin, and outer weekly assembly goes out pimple, papulovesicle, chaps and the pain phenomenon.Relatively more obstinate by common treatment means slow curative effect, curing needs the long period, and the patient not only bears painful torment, but also will pay heavy financial burden, has no way out again, and suffering from does not have more effective treatment means.

Summary of the invention

The present invention is directed to the problem that prior art exists, provide a kind of to acute and chronic eczema and skin Pruritus instant effect, short treating period cure rate height, minimizing patient suffering and financial burden, cure in acute stage as far as possible again, do not make it become chronic eczema, and delay treatment time because of malpractice; The external medicine preparation of the acute and chronic eczema of treatment for the treatment of both the principal and secondary aspects of a disease has no side effect.

Pharmaceutical preparation of the present invention is by following raw materials according by weight, through being prepared from:

Radix Glycyrrhizae 10-15, Flos Lonicerae 15-18, Radix Sophorae Flavescentis 10-15, Alumen 15-18, Geranium strictipes R. Kunth 20-25, Borneolum Syntheticum 5-10, Radix Astragali 15-18, Radix Et Rhizoma Rhei 10-15, Herba Taraxaci 5-8 and Radix Paeoniae Rubra 15-18.

Pharmaceutical preparation of the present invention, the weight proportion of its raw material is as follows:

Radix Glycyrrhizae 12, Flos Lonicerae 16, Radix Sophorae Flavescentis 13, Alumen 15, Geranium strictipes R. Kunth 25, Borneolum Syntheticum 5, the Radix Astragali 18, Radix Et Rhizoma Rhei 10, Herba Taraxaci 8 and Radix Paeoniae Rubra 15.

Each component in the prescription of the present invention, what have has blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, detoxicating, killing bacteria, an anti-inflammatory analgetic and antipruritic; What also have has a tonifying Qi and lifting yang, and benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening.Above-mentioned ten flavor crude drug compatibilities performance synergistic functions, and be verified by clinical trial, and then visible prescription of the present invention is scientific and reasonable are distinguished that disease executing controlled to obtain effect preferably.

The present invention compared with prior art has following advantage and good effect:

1, pharmaceutical preparation of the present invention, to acute eczema instant effect, evident in efficacy, external application focus one is thorough more, does not also find because of malpractice or untimelyly causes being chronic case in experimental stage;

2, the case of chronic eczema was cured at 7-10 days usually and needn't use other oral medicine, cure the back and be difficult for recurring;

3, obviously reduce patient's misery,, reduce and to scratch and reduce the probability of infection because of its antipruritic effect is good;

4, treating both the principal and secondary aspects of a disease has no side effect, and short treating period is again only to use external application pharmaceutical preparation of the present invention, reduces patient's treatment cost.

The specific embodiment

Embodiment 1, by 15 parts of prescription 12 parts of extracting liquorices, 16 parts of Flos Loniceraes, 13 parts of Radix Sophorae Flavescentiss, 25 parts of Geranium strictipes R. Kunths, 18 parts of the Radixs Astragali, 10 parts of Radix Et Rhizoma Rhei, 8 parts of Herba Taraxacis and Radix Paeoniae Rubra, went into to add again behind the container the heavy water loggings bubble of five times of medicines together two hours, it is little fiery one hour after heating extraction is waited to boil, after getting water that its medicinal residues of liquid add four times of amounts again and boiling, add 5 parts of Alumen part and Borneolum Syntheticums again, got liquid, twice medicinal liquid is merged in little fiery one hour, stir, be concentrated into thick bottling, sterilization.

18 parts of embodiment 2,10 parts of extracting liquorices, 18 parts of Flos Loniceraes, 10 parts of Radix Sophorae Flavescentiss, 18 parts in Alumen, 20 parts of Geranium strictipes R. Kunths, 10 parts of Borneolum Syntheticums, 13 parts of the Radixs Astragali, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Herba Taraxacis and Radix Paeoniae Rubra, the method preparation identical, every bottle 15 gram with embodiment 1.

The method preparation that 16 parts of 6 parts of embodiment 3,15 parts of extracting liquorices, 15 parts of Flos Loniceraes, 15 parts of Radix Sophorae Flavescentiss, 17 parts in Alumen, 23 parts of Geranium strictipes R. Kunths, 7 parts of Borneolum Syntheticums, 15 parts of the Radixs Astragali, 13 parts of Radix Et Rhizoma Rhei, Herba Taraxaci and Radix Paeoniae Rubra and embodiment 1 are identical.

For further examination pharmaceutical preparation of the present invention,, select each 50 example of acute and chronic eczema patients at random from department of dermatologry to the curative effect of indication; Alternative is selected old itching disease patient and is carried out clinical trial:

Criterion as a result

1, more its symptom complete obiteration entirely;

2, effectively its symptom makes moderate progress;

3, invalid its doing well,improving is not obvious.

Application method: with pharmaceutical preparation of the present invention, be applied to focus surface skim, the morning, noon and afternoon respectively once

Observing time: five days is a course of treatment, and this is observed and was off-test in ten days.

At the inactive other drug of duration of test, change dressings by the test requirements document medicine-feeding, acute and chronic patient 100% has improvement when test proceeds to the 3rd day, sx such as pimple reduction of area are little, the Pruritus situation all has clear improvement, little not irritated to skin irritation, observe when test proceeds to the 5th day, wherein existing 48 of acute patient is healed entirely, and two people are sepage except after scratching in addition, rotten to the corn shape is got better with the pustule symptom but Shang Weiquan is good; Chronic patients all obviously takes effect, but also incomplete more person, the complete more person of observation has reached 98 people when test proceeds to ten days, and chronic patients has two people not reach complete more standard as yet.Although the test case is few, clinical time is not long, and pharmaceutical preparation of the present invention is definite to the curative effect of indication, and is particularly even more ideal to the antipruritic effect of old itching disease, all realizes satisfactory results at five days duration of test.

Claims (2)

1. treat the external medicine preparation of acute and chronic eczema, it is characterized in that it being to compare through being prepared from by following raw materials by weight portion:

Radix Glycyrrhizae 10-15, Flos Lonicerae 15-18, Radix Sophorae Flavescentis 10-15, Alumen 15-18, Geranium strictipes R. Kunth 20-25, Borneolum Syntheticum 5-10, Radix Astragali 15-18, Radix Et Rhizoma Rhei 10-15, Herba Taraxaci 5-8 and Radix Paeoniae Rubra 15-18.

2. pharmaceutical preparation according to claim 1 is characterized in that described raw material weight proportioning is as follows:

Radix Glycyrrhizae 12, Flos Lonicerae 16, Radix Sophorae Flavescentis 13, Alumen 15, Geranium strictipes R. Kunth 25, Borneolum Syntheticum 5, the Radix Astragali 18, Radix Et Rhizoma Rhei 10, Herba Taraxaci 8 and Radix Paeoniae Rubra 15.