CN101716309A - Medicament for treating mammary gland (lobule) hyperplasia and preparation method - Google Patents

Abstract

The invention relates to a medicament for treating mammary gland (lobule) hyperplasia and a preparation method. The medicament comprises 16 traditional Chinese medicines comprising rhizoma sparganii, pokeberry roots, curcuma zedoary, paris polyphylla, asparagus cochinchinensis, herba cistanche, malts, dried orange peels, suberect spatholobus stems, pericarpium citri reticulatae viride, lychee seeds, nutgrass galingale rhizome, tangerine seeds, turtle shells, peach kernels and licorice roots which are processed into capsule preparations easy to take. The medicament can resolve hard lumps, resist viruses, diminish inflammations, stop pain and prevent mammary gland (lobule) hyperplasia from converting into mammary gland tumors. The effective rate of the medicament for treating the mammary gland (lobule) hyperplasia is 99 percent, the cure rate is higher than 92 percent, and recurrence is not easy to occur after healing. The medicament is easy to store and convenient to use.

Description

Outgrowth medicine of a kind of treatment mammary gland (lobule) and preparation method

The present invention is the outgrowth medicine of a kind of treatment mammary gland (lobule), the invention belongs to the technical field of Chinese medicine preparation and preparation method.

Mammary gland (lobule) hypertrophy is that the women is through common mastopathy.The glossology of primary disease is very chaotic, has another name called cyclomastopathy, mammary dysplasia disease, Fibrocystic disease etc.Once be called chronic cystic mastitis, in fact the primary disease NIP sexually revises in the past, thereby should not use.The characteristics of primary disease are the hypertrophy of mammary gland constituent, show on structure, quantity and tissue morphology unusually, also are called cystic hyperplasia or mammary dysplasia disease.

Cyclomastopathy is meant breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and the newborn lobule degeneration structurally and the growth of carrying out property connective tissue, and its pathogenic factor mainly is because the endocrine hormone imbalance.The traditional Chinese medical science is thought: feelings are not smooth, and irritability must not normally be dredged and be rushed down and the qi stagnation blood stasis disease is coagulated, and dashes the uncomfortable person of wantonly two arteries and veins, menoxenia is often arranged, facial colour spot.Modern medicine is thought: the external environment of marriage and childbirth, meals, people living and inherited genetic factors are mammary gland (lobule) morbidity main causes.(1) mastalgia: often be distending pain or twinge, can involve the one or both sides breast, see that so that a lateral deviation is heavy the pain severe patient can not be touched more, even influence daily life and work.Pain also can be to Ipsilateral axillary fossa, the breast side of body or the radiation of shoulder back based on the lump in breast place; Some then shows as sore nipples or itches.Mastalgia often before menstruation a couple of days occur or increase the weight of, the back pain of passing through obviously alleviates or disappears; Pain also can fluctuate with emotion changes.This pain relevant with menstrual cycle and emotion changes is the main feature of cyclomastopathy clinical manifestation.(2) lump in breast: lump can be sent out in one-sided or bilateral breast, and is single or multiple, and good sending out gone up quadrant outside breast, also be found in other quadrants.The lump shape has sheet bulk, Semen Viciae fabae nodositas, streak, graininess etc., wherein block for seeing with sheet more.The lump border is not obvious, and quality is medium or tough slightly firmly, and is movable good, do not have adhesion with surrounding tissue, and tenderness is often arranged.Lump is not of uniform size, and is big as little person such as the foxtail millet grain, and big person can exceed 3～4cm.Lump in breast also has the characteristics that change with menstrual cycle, and lump increases hardening before the menstruation, and lump dwindles deliquescing behind the menstrual onset.(3) nipple discharge: nipple discharge can appear in small number of patients, are spontaneous discharge, olive drab(O or brown serosity discharge.(4) menoxenia: this patient can with before and after the menstruation irregularly, amount less or color light, can accompany dysmenorrhea.(5) feelings will changes: the normal emotion will of patient smooth or susceptible to lose temper due to restlessness, anger, psychentonia or tired postemphasis whenever.

Clinical manifestation: (1) caused by hepatic stagnation qi stagnation: preceeded menorrhea or breast swell and pain menstrual period, disappear with susceptible to anger, the beading joint knot that a side or bilateral can be laid one's hand on and differ in size, lump mostly are the big trifle knot of Semen phaseoli radiati, Semen Viciae fabae shape tuberosity or become slightly streak.Matter is tough not hard, presses movably, and not with the deep tissue adhesion, the border is situated between unclear, and the menstrual cycle deficiency is more through measuring, heating installation uncomfortable in chest, spirit depressing, susceptible to lose temper due to restlessness.(2) dash the uncomfortable type of wantonly two arteries and veins: breast has lump, through preceding or menstrual period pain increase the weight of, behind row, alleviate or disappear, prolong after more than menstrual period, dysmenorrhoea is not acute, hypomenorrhea, body is tired unable, soreness of waist cold extremities, the lower abdomen fear of cold, the mistake person of controlling with the passing of time, canceration can take place in minority.The excision specimen often is yellow-white, and matter is tough, no peplos.Tangent plane is seen sometimes a lot of folliculus that loose, and is actually the big ductule of cryptomere expansion, and cyst wall is level and smooth mostly, in yellow green or brown viscous liquid are arranged.Sometimes there is the cheesy material of yellow-white to overflow from the mouth of pipe.As be the diffusivity cystic disease, then claim the schimmelbusche disease.The cyan cyst that single tension force is bigger claims blue dome cyst.The chance that epidemiological study points out the cystic hyperplasia patient that breast carcinoma takes place later on is 2～4 times of normal population.It is relevant with its ductal epithelium hyperplasia degree whether cystic hyperplasia itself can cancerate.The cystic hyperplasia of simple property seldom has and cancerates, if with epithelial dysplasia, and severe person particularly, what then cancerate may be bigger, belongs to precancerous lesion.Patient often has the one or both sides distending pain of the breast, and the lighter such as acupuncture sample can involve shoulder, upper limb or chest and back.Generally obvious before menstrual onset, pain relief or disappearance behind the menstrual onset.The circular tuberosity that is dispersed in is arranged in the breast during inspection, differ in size, matter is tough, and tenderness is arranged sometimes.Tuberosity is unclear with the boundary of mammary gland tissue on every side, with skin or chest muscle adhesion, does not show as ill-defined buildup area sometimes.It is more that focus is positioned at the outer top of breast, also can have influence on whole breast.A few patients can have nipple discharge, often is brown, serosity or bloody fluid.The course of disease is very long sometimes, but symptom Chang Zidong disappears or alleviates after the menolipsis.

The present used medicine of treatment: conventional medicines such as RUPIXIAO, ease pill take effect slowly, act on not obvious, easy recurrence etc., and only a few patient's hatefulness turns to breast carcinoma.Numerous mammary gland (lobule) hypertrophy patient demands a kind of effective medicine urgently and uses.

Medicine of the present invention is: rhizoma sparganic, Radix Phytolaccae, Rhizoma Curcumae, Rhizoma Paridis, Radix Asparagi, Herba Cistanches, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae, Caulis Spatholobi, Pericarpium Citri Reticulatae Viride, Semen Litchi, Rhizoma Cyperi, Semen Citri Reticulatae, Carapax Trionycis, Semen Persicae, Radix Glycyrrhizae ten Six-element Chinese medicines are formed.

Per 200 capsules patent medicine contain by the dose proportioning: rhizoma sparganic 9 grams, Radix Phytolaccae 9 grams, Rhizoma Curcumae 9 grams, Rhizoma Paridis 9 grams, Radix Asparagi 6 grams, Herba Cistanches 6 grams, Fructus Hordei Germinatus 5 grams, Pericarpium Citri Reticulatae 2 grams, Caulis Spatholobi 10 grams, Pericarpium Citri Reticulatae Viride 3 grams, Semen Litchi 5 grams, Rhizoma Cyperi 6 grams, Semen Citri Reticulatae 5 grams, Carapax Trionycis 9 grams, Semen Persicae 3 grams, Radix Glycyrrhizae 4 grams.Crude drug is totally 100 grams.

Production technology of the present invention is:

1, medicine is weighed accurately by recipe quantity.

2, above medical material being put into the medicinal material pulverizer pulverizing is 120 order medicated powder.

3, medicated powder being poured into container stirs standby.

4, the medicated powder fill after pulverizing is stirred packages spare than capsule.

At present, operation, Chinese medicine etc. are adopted in the treatment of cyclomastopathy more both at home and abroad, but the operation influence is attractive in appearance, traditional drug is difficult to cure mostly, and the course of disease is short, and development is fast, still can recur behind most of patient treatment again.

The side separates: rhizoma sparganic: hard masses softening and resolving, and the gas in the kind removing blood stasis, Liver Channel blood system medicine is controlled the long-pending hard person of piece skin ulcer, logical Liver Channel hematocele, it is swollen hard to control skin ulcer; Rhizoma Curcumae: the circulation of qi promoting removing blood stasis, the removing food stagnancy pain relieving, antiinflammatory, antitumor prevent to cancerate, and the energy enhancing immunity; Radix Phytolaccae: detoxicating and resolving stagnation of pathogens, the detumescence of relieving oedema or abdominal distension through diuresis or purgation, and the promotion immunologic function is arranged; Radix Asparagi: nourishing YIN to relieve dryness.Antibiotic, antitumor, control nodules of the breast; Herba Cistanches: the kidney invigorating benefit blood, control cyclomastopathy; Fructus Hordei Germinatus: the removing food stagnancy galactopoiesis, control cyclomastopathy; Pericarpium Citri Reticulatae: regulating QI and lowering the adverseness, drying dampness to eliminate phlegm, can treat cyclomastopathy; Caulis Spatholobi; Promoting blood flow to regulate menstruation promotes the leukocyte growth, and favourable nodules of the breast is healed soon; Pericarpium Citri Reticulatae Viride: soothing liver-QI dispelling the stagnated QI, removing food stagnancyization stagnate, and prevent and treat the retrograde mammary gland of irritability alluvial; Semen Litchi: promoting QI to circulate and dispersing the agglomeration of the pathogens, the pain that relieves the pain, to alleviate the pain of cyclomastopathy; Rhizoma Cyperi: promoting QI circulation for relieving depression are used for the mammary gland pain due to the stagnation of QI due to depression of the liver; Semen Citri Reticulatae: regulate the flow of vital energy, eliminating stagnation, relieve the pain, prevent and treat cyclomastopathy; Carapax Trionycis: nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving is favourable with the absorption of hypertrophy mammary gland; Semen Persicae: blood circulation promoting and blood stasis dispelling is used for the lump in the abdomen mass in the abdomen; Radix Glycyrrhizae: coordinating the actions of various ingredients in a prescription, contain hormone, strengthen drug effect.

Full side's concerted application of drugs is reasonable, and treating both the principal and secondary aspects of a disease has significant curative effect for mammary gland (lobule) hypertrophy patient, totall effective rate in clinical treatment 99%, and wherein cure rate 92%, and more the back is difficult for recurrence, and curative effect obviously is better than existing clinical application.

Embodiment 1: Zhang Xiaoyi, woman, 36 years old, cyclomastopathy was suffered from before 3 years by the prosperous extra large electrical apparatus factory in Linqu, Shandong Province, in county institute of traditional Chinese medicine treatment by Chinese herbs half a year, curative effect is not obvious, change one course of treatment of clothes medicine of the present invention, positive effect is just arranged, pain relief, tuberosity reduces, continued to take 1 course of treatment, the symptom complete obiteration is now followed up a case by regular visits to and is not had recurrence.

Embodiment 2: Wang Rong, and the woman, the Linqu Choreographer suffered from cyclomastopathy 2 years half, once took: RUPIXIAO, ease pill etc., heavy when light during symptom, accept my this invention medicine treatment, course of treatment recovery from illness, revisiting does not have recurrence.

Embodiment 3: Zhang Jing, woman.37 years old, the professor of Weifang College suffered from cyclomastopathy 4 years, and breast went up painful seriously when particularly official holiday came, and dare not run, and Chinese and western medicine has been seen Duo Jia, and curative effect is very little, took medicine of the present invention through friend's introduction, 2 the course of treatment symptom completely without, reach the clinical cure purpose.

Claims (3)

1. treat the outgrowth medicine of mammary gland (lobule) for one kind, it is characterized in that this medicine is is that raw material is made with the Chinese herbal medicine, its raw material is composed as follows: rhizoma sparganic 9 grams, Radix Phytolaccae 9 grams, Rhizoma Curcumae 9 grams, Rhizoma Paridis 9 grams, Radix Asparagi 6 grams, Herba Cistanches 6 grams, Fructus Hordei Germinatus 5 grams, Pericarpium Citri Reticulatae 2 grams, Caulis Spatholobi 10 grams, Pericarpium Citri Reticulatae Viride 3 grams, Semen Litchi 5 grams, Rhizoma Cyperi 6 grams, Semen Citri Reticulatae 5 grams, Carapax Trionycis 9 grams, Semen Persicae 3 grams, Radix Glycyrrhizae 4 grams, crude drug is totally 100 grams.

2. according to the outgrowth medicine of the described a kind of mammary gland of claim one (lobule), it is characterized in that pharmaceutical formulation of the present invention.

3. according to the outgrowth medicine of the described treatment mammary gland of claim 1----2 (lobule), it is characterized in that preparation method of the present invention may further comprise the steps:

1) with Chinese medicinal herbs by the recipe quantity standard of weighing.

2) will weigh that to put into that medicinal material pulverizer pulverizes be 120 order medicated powder for the raw material medicine of standard.

3) medicine after will pulverizing (about 92 grams) is poured container into, and it is standby to stir.

4) will pulverize medicated powder fill 200 capsules that stir, package spare.