CN101703626A - Medicament for treating rheumatoid arthritis - Google Patents

Medicament for treating rheumatoid arthritis Download PDF

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CN101703626A
CN101703626A CN200910230990A CN200910230990A CN101703626A CN 101703626 A CN101703626 A CN 101703626A CN 200910230990 A CN200910230990 A CN 200910230990A CN 200910230990 A CN200910230990 A CN 200910230990A CN 101703626 A CN101703626 A CN 101703626A
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radix
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medicine
rhizoma
root
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CN101703626B (en
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阚恭勇
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Tang Yanchun
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Abstract

The invention provides a medicament for treating rheumatoid arthritis, which belongs to the field of Chinese medicinal preparations. The medicament comprises the following components in part by weight: 10 to 30 parts of rhizoma corydalis, 20 to 50 parts of hawthorn fruit, 10 to 30 parts of figwort root, 10 to 50 parts of red paeony root, 1 to 10 parts of Chinese angelica, 5 to 20 parts of scorpion, 1 to 20 parts of divaricate saposhnikovia root, 10 to 20 parts of salivia chinensis, 10 to 30 parts of mulberry root, 1 to 10 parts of liquoric root, 10 to 50 parts of incised notopterygium rhizome, 10 to 20 parts of tuber fleeceflower stem, 10 to 30 parts of cassia twig and 10 to 30 parts of medlar. The medicament has the effects of warming and activating meridian, building up vital energy and nourishing the blood, clearing away heat and removing dampness and eliminating cold to stop pain, has no side effect, and can achieve the aim of addressing both the symptoms and root causes.

Description

A kind of medicine for the treatment of rheumatic arthritis
Technical field
The present invention relates to a kind of Chinese medicine preparation, specifically a kind of medicine for the treatment of rheumatic arthritis.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT.Can show effect repeatedly and involve heart.Clinical one is miserable with joint and muscle migration, heavily outstanding, pain is feature. belong to allergic disease. and be one of main performance of rheumatic fever, how with febris acuta and arthralgia onset, typical case's performance is slight or the moderate heating, migratory polyarthritis, the joint of getting involved mostly is the knee joint ankle, shoulder, big joint such as elbow wrist, commonly be transferred to another joint; the pathological changes part presents redness; scorching hot; severe pain part patient also has several joints to fall ill simultaneously; atypical patient only has arthralgia and do not have other inflammation performances; acute inflammation generally disappears in 2-4 week and do not stay sequela by a joint, but the Chang Fanfu outbreak.If active rheumatism influences heart and myocarditis then can take place even leave over valve disorder.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of rheumatic arthritis.
China's Huangdi's Internal Classics cold-damp three gas of keeping watch are collectively referred to as numbness.Because involving the joint mostly, rheumatism causes pain, so rheumatic arthritis one speech is used till today always." element is asked the numbness opinion " points out " wind, cold, wet three gas are assorted extremely, close and are numbness, its migratory BI-syndrome caused mainly by pathogenic wind, BI-syndrome caused mainly by pathogenic cold being called painful BI, the BI syndrome caused mainly by pathogenic dampness being called fixed BI ", " so-called numbness person, each with reinfection at that time in the wet person of wind and cold also ".In addition, " element is asked the numbness opinion " also think " so-called diet residence place, be its sick this ", the generation of numbness disease is relevant with diet and living environment again.And in " element is asked and commented pyretography ", say: " the wind and rain cold and heat must not be empty, can not solely hurt sb.'s feelings ", " not closing, " so be not numbness with the wind and cold dampness; Wind, cold, wet, pathogenic heat are the external condition that development takes place rheumatic arthritis, and all empty internal memories, positive QI-insufficiency is being the inside reason of its morbidity; In addition, blood stasis expectorant is turbid can be the cause of disease of bringing out rheumatic arthritis, also is the pathologic product of the pathogenic factor effect on human body of rheumatic arthritis.On the one hand, the morbidity of rheumatic arthritis is thought positive QI-insufficiency in the traditional Chinese medical science, and the imbalance of internal organs negative and positive of qi and blood is its inner key factor, and can produce blood stasis and phlegm retention.And on the other hand, rheumatic arthritis is again a kind of chronic touching pathological changes with the passing of time, lingers on the passing of time, is harmonious with the effect of exopathogen, can increase the weight of blood stasis again and expectorant is turbid.The present invention adopts Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Scrophulariae, Scorpio, Caulis Polygoni Multiflori to be used for wind, cold, wet, pathogenic heat, and Radix Glycyrrhizae, Ramulus Cinnamomi, Radix Angelicae Sinensis, Fructus Lycii are used for positive QI-insufficiency, the imbalance of internal organs negative and positive of qi and blood, adopts Rhizoma Corydalis, Fructus Crataegi, Radix Paeoniae, that Cortex Moutan is used for congestion expectorant is turbid.
Medicine pharmacology of the present invention is as follows:
Rhizoma Corydalis: [nature,taste and action] Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.Promoting blood circulation to remove blood stasis is arranged, promoting the circulation of QI analgesic function.
[curing mainly usage] is used for pain of each qi depression to blood stasis of whole body, dysmenorrhea, and amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.Be decocted in water for oral dose.
Fructus Crataegi: [nature and flavor] sour in the mouth, sweet, slightly warm in nature.
[function cures mainly] appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.Be used for carnivorous stagnate long-pending, lump in the abdomen, abdominal distention feeling of fullness, the stasis of blood resistance stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc.
Radix Scrophulariae: [meridian distribution of property and flavor] sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel.
[effect] clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.
[curing mainly] pathogenic warmth is joined the army, the pericardium that caves in, and maculae caused by violent heat pathogen, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin.
Radix Paeoniae Rubra: [meridian distribution of property and flavor] hardship is slightly cold.Return Liver Channel.
[function cures mainly] clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Radix Angelicae Sinensis: [nature and flavor with return through] are sweet, hot, temperature.Return liver, the heart, spleen channel.
[function with cure mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.Be used for the amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Scorpio: [meridian distribution of property and flavor] suffering, flat; Poisonous.Return Liver Channel.
[function cures mainly] endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula
Radix Saposhnikoviae: [meridian distribution of property and flavor] acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.
[effect] expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.
[curing mainly] diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Cortex Moutan: [meridian distribution of property and flavor] is cold in nature, bitter in the mouth, suffering.GUIXIN, liver, kidney channel.
[function cures mainly] clearing away heat and cooling blood, blood circulation promoting competent silt.Be used for maculae caused by violent heat pathogen, tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, the amenorrhea dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury.
Radix Mori: [effect] heat clearing away arresting convulsion; Dispelling wind and removing obstruction in the collateral
[nature and flavor] little hardship; [curing mainly] cold in nature infantile convulsion; Conjunctival congestion; Toothache; Bones and muscles pain
Radix Glycyrrhizae: [function cures mainly]: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Rhizoma Et Radix Notopterygii: [meridian distribution of property and flavor] is hot, bitter, temperature.Return bladder, kidney channel.
[function cures mainly] cold expelling dispels the wind, dehumidifying, pain relieving.Be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Caulis Polygoni Multiflori: [meridian distribution of property and flavor]: sweet, flat.
[effect] nourishes heart, and calms the nerves, and collateral dredging dispels the wind,
[curing mainly] controls the insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
Fructus Lycii: [effect]: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.
[curing mainly]: the treating the liver kidney yin is lost, soreness of the waist and knees, and dizziness, dizzy, the many tears of blurred vision, cough due to consumptive disease is quenched one's thirst, seminal emission.
Ramulus Cinnamomi: [meridian distribution of property and flavor] is hot, sweet, temperature.GUIXIN, lung, urinary bladder channel.
[effect] diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
This medicine is formed by following composition proportion:
Rhizoma Corydalis 10-30 part Fructus Crataegi 20-50 part Radix Scrophulariae 10-30 part Radix Paeoniae Rubra 10-50 part
Radix Angelicae Sinensis 1-10 part Scorpio 5-20 part Radix Saposhnikoviae 1-20 part Cortex Moutan 10-20 part
Radix Mori 10-30 part Radix Glycyrrhizae 1-10 part Rhizoma Et Radix Notopterygii 10-50 part Caulis Polygoni Multiflori 10-20 part
Ramulus Cinnamomi 10-30 part Fructus Lycii 10-30 part,
Its preparation method is as follows:
(1), after being fried with the temperature fire, Radix Angelicae Sinensis, Radix Glycyrrhizae be ground into fine powder.
(2), wrap up in together with Fructus Crataegi, Fructus Lycii with Rhizoma Corydalis, Ramulus Cinnamomi, Radix Scrophulariae, Radix Paeoniae Rubra, Scorpio, Radix Saposhnikoviae, Cortex Moutan, Radix Mori, Rhizoma Et Radix Notopterygii, Caulis Polygoni Multiflori, with gauze and to put into marmite, decoct with water 30-45 minute, get its medicinal liquid.
(3), the powder in (1) is added in (2) herb liquid, stir evenly and get final product.
This medicine is formed by following composition proportion:
Rhizoma Corydalis 15-25 part Fructus Crataegi 25-40 part Radix Scrophulariae 12-26 part Radix Paeoniae Rubra 20-45 part
Radix Angelicae Sinensis 2-8 part Scorpio 7-18 part Radix Saposhnikoviae 4-17 part Cortex Moutan 12-18 part
Radix Mori 12-26 part Radix Glycyrrhizae 2-7 part Rhizoma Et Radix Notopterygii 20-40 part Caulis Polygoni Multiflori 12-19 part
Ramulus Cinnamomi 15-27 part Fructus Lycii 15-25 part.
This medicine is formed by following composition proportion:
6 parts of 30 parts of Radix Angelicae Sinensis of 20 parts of Radix Paeoniae Rubra of 30 portions of Radix Scrophulariaes of 20 portions of Fructus Crataegis of Rhizoma Corydalis
5 parts in 20 portions of Radix Glycyrrhizaes of 15 parts of Radix Mori of 12 parts of Cortex Moutans of 12 parts of Radix Saposhnikoviaes of Scorpio
19 parts of 21 portions of Fructus Lyciis of 16 parts of Ramulus Cinnamomi of 30 parts of Caulis Polygoni Multiflori of Rhizoma Et Radix Notopterygii.
Medicine of the present invention has nourishing qi and blood, nourishing the lung to arrest cough, warming the meridian and promoting blood circulation, removing damp-heat, dispersing cold for relieving pain, effects such as blood circulation promoting competent silt, but the smart various symptoms and signs of deficiency of tonification is avoided positive QI-insufficiency; Promote battalion to defend mediation, the defence pathogen is invaded health.The cure rate height does not recur, has no side effect.
Embodiment
Embodiment 1:
25 parts of 17 parts of Radix Paeoniae Rubra of 28 portions of Radix Scrophulariaes of 18 portions of Fructus Crataegis of Rhizoma Corydalis
13 parts of 8 parts of Cortex Moutans of 10 parts of Radix Saposhnikoviaes of 5 portions of Scorpios of Radix Angelicae Sinensis
14 parts of 27 parts of Caulis Polygoni Multiflori of 3 portions of Rhizoma Et Radix Notopterygiis of 18 portions of Radix Glycyrrhizaes of Radix Mori
17 parts of 19 portions of Fructus Lyciis of Ramulus Cinnamomi,
Its preparation method is as follows:
(1), after being fried with the temperature fire, Radix Angelicae Sinensis, Radix Glycyrrhizae be ground into fine powder.
(2), wrap up in together with Fructus Crataegi, Fructus Lycii with Rhizoma Corydalis, Ramulus Cinnamomi, Radix Scrophulariae, Radix Paeoniae Rubra, Scorpio, Radix Saposhnikoviae, Cortex Moutan, Radix Mori, Rhizoma Et Radix Notopterygii, Caulis Polygoni Multiflori, with gauze and to put into marmite, decoct with water 30-45 minute, get its medicinal liquid.
(3), the powder in (1) is added in (2) herb liquid, stir evenly and get final product.
Embodiment 2:
This medicine is formed by following composition proportion:
35 parts of 22 parts of Radix Paeoniae Rubra of 35 portions of Radix Scrophulariaes of 22 portions of Fructus Crataegis of Rhizoma Corydalis
16 parts of 14 parts of Cortex Moutans of 15 parts of Radix Saposhnikoviaes of 7 portions of Scorpios of Radix Angelicae Sinensis
17 parts of 35 parts of Caulis Polygoni Multiflori of 4 portions of Rhizoma Et Radix Notopterygiis of 22 portions of Radix Glycyrrhizaes of Radix Mori
20 parts of 25 portions of Fructus Lyciis of Ramulus Cinnamomi,
Its preparation method is identical with embodiment 1.
Usage and consumption:
Take twice every day, sooner or later respectively once.
Criterion of therapeutical effect
1, cure: transference cure, joint motion are normal.
2, produce effects: symptom disappears substantially, and joint motion is normal substantially.
3, take a turn for the better: symptom makes moderate progress.
4, invalid: symptom does not all have improvement.
Medicine of the present invention carries out clinical treatment to 90 routine patients, male's 40 examples wherein, and women's 50 examples, oldest is 65 years old, minimum is 16 years old; Cure 70 examples, produce effects 12 examples, 5 examples that take a turn for the better, invalid 3 examples, total effective rate reaches 96.7%. and is exemplified below:
Case 1: Lee, the man, 43 years old, wrist joint swelled and ache the year before, and increase gradually in the joint of then swelling and ache, and all get involved in big joint such as knee joint ankle, shoulder, elbow wrist, and the pathological changes part presents redness, scorching hot situation.Use this medicine after 35 days, symptom disappears substantially, after adhering to again taking January,
Case 2: Zhang, the woman, symptom shows as the joint and the muscle migration is miserable, heavily outstanding, pain, and activity can not have a strong impact on daily life freely.After taking this medicine, symptom alleviates gradually, took for 4 weeks after, physical recovery is normal.
Case 3, Wang, woman 30 years old, two knee joint pain appear in certain worker of enterprise several years ago, and particularly the pain increased during change in weather, is diagnosed as rheumatic arthritis.Continue to take medicine of the present invention after January in October, 07, transference cure, and it is normal that health is recovered, so far not recurrence.
Case 4: the gold certain, the man, 42 years old, certain cause unit personnel, its symptom is a double knee joint pain, four seasons pain, then multi-joint is got involved, the state of an illness increases the weight of during awful weather, through failing to respond to any medical treatment for many years.Take this medicine after 2 weeks, symptom alleviates to some extent, and after continuing to take January, pain disappears, and visits so far not recurrence.
Case 5: Xu certain, the woman, 38 years old, the pain of knee articular sensation several years ago, last difficulty comparatively downstairs the time, sx during change in weather bends and stretches difficulty, after the fruit of failing to respond to any medical treatment for many years.Adhere to using this medicine after 40 days, transference cure is not violated so far.
Case 6: the week certain, woman, 27 years old, the employee, after athletic meeting one day, because of weather overheated, the temperature of turning on the aircondition is low excessively, headache next day, heating, whole body arthralgia, after 2 weeks, arthralgia aggravation, joint stuffiness, after hospital diagnosis and take Western medicine after, ill symptomses such as abdominal part dull pain occur, can't adhere to; Through taking this medicine after 3 weeks, pain disappears, not recurrence.
Case 7: grandson, the woman, 37 years old, arthralgia was diagnosed as rheumatic arthritis in hospital for many years, after take hormone, analgesic, and attempted various naturopathy methods, effect is all not obvious, then, increase in the joint of getting involved, handicapped.Using this medicine after January, symptom takes a turn for the better, after continuing to take January, and transference cure, activity is freely.
Case 8: Hu, 26 years old, do not have obvious inducement the year before and begin to occur lumbago, activity more very, lumbago is alleviated after several days, pain and double knee joint, after gradually be developed to the duplex joint, carpal joint and two ankle joint are migration, the pain joint motion is unfavorable, does not have stiff phenomenon, double knee joint mild swelling on inspection of obvious morning, not red, local skin Wen Bugao, light tenderness, the little joint of limb end does not have deformity.Be diagnosed as rheumatic arthritis.After take medicine and stick on medicine treatment, the state of an illness take a favorable turn, but day cool pain increases the weight of.After after using this medicine, sx after January, pain relief, swelling disappears.Continue to use after 2 months, the symptom complete obiteration, pain disappears, and activity is freely.It is normal that life recovers.

Claims (3)

1. medicine for the treatment of rheumatic arthritis is characterized in that this medicine is formed by following composition proportion:
Rhizoma Corydalis 10-30 part Fructus Crataegi 20-50 part Radix Scrophulariae 10-30 part Radix Paeoniae Rubra 10-50 part
Radix Angelicae Sinensis 1-10 part Scorpio 5-20 part Radix Saposhnikoviae 1-20 part Cortex Moutan 10-20 part
Radix Mori 10-30 part Radix Glycyrrhizae 1-10 part Rhizoma Et Radix Notopterygii 10-50 part Caulis Polygoni Multiflori 10-20 part
Ramulus Cinnamomi 10-30 part Fructus Lycii 10-30 part,
Its preparation method is as follows:
(1), after being fried with the temperature fire, Radix Angelicae Sinensis, Radix Glycyrrhizae be ground into fine powder.
(2), wrap up in together with Fructus Crataegi, Fructus Lycii with Rhizoma Corydalis, Ramulus Cinnamomi, Radix Scrophulariae, Radix Paeoniae Rubra, Scorpio, Radix Saposhnikoviae, Cortex Moutan, Radix Mori, Rhizoma Et Radix Notopterygii, Caulis Polygoni Multiflori, with gauze and to put into marmite, decoct with water 30-45 minute, get its medicinal liquid.
(3), the powder in (1) is added in (2) herb liquid, stir evenly and get final product.
2. a kind of medicine for the treatment of rheumatic arthritis according to claim 1 is characterized in that this medicine is formed by following composition proportion:
Rhizoma Corydalis 15-25 part Fructus Crataegi 25-40 part Radix Scrophulariae 12-26 part Radix Paeoniae Rubra 20-45 part
Radix Angelicae Sinensis 2-8 part Scorpio 7-18 part Radix Saposhnikoviae 4-17 part Cortex Moutan 12-18 part
Radix Mori 12-26 part Radix Glycyrrhizae 2-7 part Rhizoma Et Radix Notopterygii 20-40 part Caulis Polygoni Multiflori 12-19 part
Ramulus Cinnamomi 15-27 part Fructus Lycii 15-25 part.
3. a kind of medicine for the treatment of rheumatic arthritis according to claim 1 is characterized in that this medicine is formed by following composition proportion:
6 parts of 30 parts of Radix Angelicae Sinensis of 20 parts of Radix Paeoniae Rubra of 30 portions of Radix Scrophulariaes of 20 portions of Fructus Crataegis of Rhizoma Corydalis
5 parts in 20 portions of Radix Glycyrrhizaes of 15 parts of Radix Mori of 12 parts of Cortex Moutans of 12 parts of Radix Saposhnikoviaes of Scorpio
19 parts of 21 portions of Fructus Lyciis of 16 parts of Ramulus Cinnamomi of 30 parts of Caulis Polygoni Multiflori of Rhizoma Et Radix Notopterygii.
CN2009102309907A 2009-11-27 2009-11-27 Medicament for treating rheumatoid arthritis Expired - Fee Related CN101703626B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104548048A (en) * 2015-01-29 2015-04-29 马成英 Traditional Chinese medicine composition for treating rheumatic tendon and bone diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104548048A (en) * 2015-01-29 2015-04-29 马成英 Traditional Chinese medicine composition for treating rheumatic tendon and bone diseases

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