CN101653590A - Medicine for treating habitual abortion and preparation method thereof - Google Patents
Medicine for treating habitual abortion and preparation method thereof Download PDFInfo
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- CN101653590A CN101653590A CN200910075419A CN200910075419A CN101653590A CN 101653590 A CN101653590 A CN 101653590A CN 200910075419 A CN200910075419 A CN 200910075419A CN 200910075419 A CN200910075419 A CN 200910075419A CN 101653590 A CN101653590 A CN 101653590A
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicine for treating habitual abortion which takes Chinese angelica, szechuan lovage rhizome, radix astragali, large-head atractylodes rhizome, cervus nippon temminck, theseed of Chinese dodder, eucommia bark, teasel, donkey-hide glue, fritillaria cirrhosa, fructus amomi, Chinese mugwort leaf, liquorice, radix scutellariae, gardenia florida, bamboo shavings, ginger, radix paeoniae alba, polygonatum, bupleurum and caulis perllae as raw materials; and the raw materials of the medicine are mixed and ground into fine powder, filled into capsules, and then sterilized toprepare capsule product. The medicine also can be made into plaster according to the conventional pharmacy method. The medicine has the functions of moderate tonifying the kidney, Guchong preventingabortion, no toxic side effect, solidifying thoroughfare and conception vessels, reinforcing fetal vitality, and tonifying the spleen and the kidney, thus having effect of tocolysis.
Description
Technical field
The present invention relates to a kind of medicine, particularly relating to a kind of is the medicine of the treatment habitual abortion of feedstock production with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Habitual abortion is meant continuous person more than 3 times, is called " habitual abortion " in the Chinese medicine, i.e. gestation 28 weeks of foot, under the fetus natural birth, and do not have a survival ability person.Miscarriage divides threatened abortion, early abortion, late abortion; Threatened abortion: have colporrhagia to continue many days more than, lower abdominal pains after all gestation, bearing down is arranged, the lumbosacral aching pain person claims threatened abortion, and the traditional Chinese medical science claims vaginal bleeding during pregnancy, frequent fetal movement.Early abortion: refer to have several weeks of menolipsis with interior miscarriage, the traditional Chinese medical science claims induced abortion.Late abortion: occur in the miscarriage of 12-28 between week, the traditional Chinese medical science claims abortion or abortion.The traditional Chinese medical science thinks that its main cause is deficiency of kidney-QI, dashes and appoint loss, instability of kidney QI or intemperate sexual intercourse injury from falling down, and deficient qi and blood causes due to the feotus vitality deficiency.And modern western medicine still lacks ideal Therapeutic Method, and the traditional Chinese medical science then advocates before pregnant in advance with control, and it is main preventing miscarriage after pregnant, the kidney invigorating commonly used, spleen invigorating, the method that solid and gas nourishes blood.Along with the great variety of social condition, the change of people's concept, above the average age for marriage marriage, or after marriage for oneself cause etc., repeatedly medicine stream or artificial abortion or take medicine improperly after pregnant, and sexual life is careless about health and causes many reasons such as uterine cavity infection, causes the patient of habitual abortion also more and more many.
Habitual abortion often occurs in same gestation month (being gestational age).In the habitual abortion, except that inspections such as dyed body get rid of cause for genetic reasons, treatment by Chinese herbs has certain effect.Chinese medicine is thought kidney storing essence and is the beginning of QI and blood, is the root of reproduction; The spleen master is good for fortune and is the biochemical source of QI and blood, is the foundation of acquired constitution.The cause of disease of habitual abortion mainly is because internal and external factor has caused the energy and blood of human body weakness, instability of kidney QI, interior-heat damaging fetus.How its Therapeutic Principle controls from the tonify deficiency opinion, is core especially with the kidney invigorating.Emphasize the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs of preventing miscarriage after prophylactic treatment before women's unpregnancy and the pregnancy is combined.At present, though the medicine and the method for some treatment habitual abortion, curative effect is not obvious.
Summary of the invention
The purpose of this invention is to provide a kind of employing Chinese herbal medicine umbilicus that applies for oral administration, the medicine of cure rate height, the treatment habitual abortion that has no side effect.
Another goal of the invention of the present invention provides the preparation method of this medicine.
Medicine of the present invention is to be crude drug with following parts of medicines by weight:
Radix Angelicae Sinensis 8～10, Rhizoma Chuanxiong 8～10, the Radix Astragali 12～15, the Rhizoma Atractylodis Macrocephalae 8～10, Cornu Cervi Degelatinatum 8～10, Semen Cuscutae 8～10, the Cortex Eucommiae 8～10, Radix Dipsaci 8～10, Colla Corii Asini 8～10, Bulbus Fritillariae Cirrhosae 4～6, Fructus Amomi 4～6, Folium Artemisiae Argyi 2～3, Radix Glycyrrhizae 2～3, Radix Scutellariae 8～10, ZHIZIREN 8～10, Caulis Bambusae In Taenia 4～6, Rhizoma Zingiberis Recens 2～3, the Radix Paeoniae Alba 8～10, Rhizoma Polygonati Odorati 4～6, Radix Bupleuri 4～6, Caulis Perillae 4～6.
The present invention is preferably, and wherein the weight proportion of each raw material is:
Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 10, Cornu Cervi Degelatinatum 10, Semen Cuscutae 10, the Cortex Eucommiae 10, Radix Dipsaci 10, Colla Corii Asini 10, Bulbus Fritillariae Cirrhosae 6, Fructus Amomi 6, Folium Artemisiae Argyi 3, Radix Glycyrrhizae 3, Radix Scutellariae 10, ZHIZIREN 10, Caulis Bambusae In Taenia 6, Rhizoma Zingiberis Recens 3, the Radix Paeoniae Alba 10, Rhizoma Polygonati Odorati 6, Radix Bupleuri 6, Caulis Perillae 6.
Said medicine can be made any dosage form on the pharmaceutics, as capsule, decoction, tablet, pill, powder;
The preferred dosage form of the present invention is a capsule; Can also make plaster by practice of pharmacy.
Concrete preparation method is:
Earlier the Folium Artemisiae Argyi parching to brown being added 1～2ml vinegar fries dried; Again Radix Glycyrrhizae is made popular and added Mel 1～2ml stir-fry to half-dried; At last above-mentioned various Chinese medicine pulverize separately are become 100～120 order fine powders, according to above-mentioned parts by weight mix homogeneously, in incapsulating, sterilization makes the capsule product.
The present invention can also press the method for pharmaceutics routine with the above-mentioned raw materials medicine, makes plaster.
We are according to theory of Chinese medical science, control with solid antiabortive towards the kidney invigorating, spleen invigorating Semen Cuscutae, the Cortex Eucommiae, Cornu Cervi Degelatinatum, Radix Dipsaci, parasitic the kidney invigorating Gu Chong in the side; The Rhizoma Atractylodis Macrocephalae, Fructus Amomi spleen invigorating are antiabortive; Radix Angelicae Sinensis, Rhizoma Chuanxiong are invigorated blood circulation antiabortive; Colla Corii Asini, Folium Artemisiae Argyi arresting bleeding and miscarriage prevention; The Radix Paeoniae Alba, Radix Bupleuri, Caulis Perillae YIN nourishing are regulated the flow of vital energy antiabortive; Radix Scutellariae, ZHIZIREN clearing heat and preventing abortion.The Bulbus Fritillariae Cirrhosae cough-relieving is antiabortive, Radix Astragali QI invigorating is antiabortive, Caulis Bambusae In Taenia, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, and stomach warming is antiabortive.
For showing the therapeutic effect of medicine of the present invention, 292 routine dermatosis patients have been carried out clinical observation on the therapeutic effect to habitual abortion.All cases be the outpatient in this county's scope, age 24-38 year, continuous three histories (comprising history of artificial abortion) of miscarrying are all arranged, and clinical all have hypogastralgia, tenesmus, lumbosacral aching pain, colporrhagia person's 176 examples.
Observation of curative effect
The 92 example treatment 1-2 months, 130 example treatments 1-4 month, 52 example treatments 1-6 month, symptom and sign disappears after treating, and the ultrasound diagnosis fetal head fetus position is normal, smoothly just before giving birth.18 routine diseases do not alleviate, and cause inevitable abortion.Tracing study, in 292 examples, 266 examples are grown normal, and are healthy clever; Find congenital heart disease 4 examples, congenital polydactylia 2 examples, anus not full cut-off is locked 2 examples.In clinical observation, do not find toxic and side effects and untoward reaction.
Model case:
Chen: 26 years old, 4 years after marriage, conceived three times, equal spontaneous abortions between pregnant 3-6 month, existing menolipsis 80 days, the pain of falling under the soreness of waist, the lower abdomen, vagina has bleeds 3 days on a small quantity.Look into light red tongue, white and thin fur, deep pulse stringy and rapid pulse.Examine to habitual abortion and give solid tire Tonga antiabortive subsides, the 3 doses of vaginal hemorrhages of taking medicine are ended, and the stomachache soreness of waist obviously alleviates, the sense of falling under having in the time of still, and 3 doses of transference cures of clothes continue.Took the 3-6 agent later in every month, clothes were to 6 months, and ultrasound diagnosis fetus position fetal rhythm is normal, conceived 10 months mature smooth product one boy babies.
Side's Chinese medicine of the present invention is gentle, is the kidney invigorating, solid towards antiabortive product, has no side effect, and Orally taken and externally makes to dash appoints admittedly, and feotus vitality foot, spleen kidney are held concurrently and mended, and has received solid tire, antiabortive effect.
The specific embodiment
Embodiment 1:
Take by weighing raw material by following proportioning:
Radix Angelicae Sinensis 100g, Rhizoma Chuanxiong 100g, Radix Astragali 150g, Rhizoma Atractylodis Macrocephalae 100g, Cornu Cervi Degelatinatum 100g, Semen Cuscutae 100g, Cortex Eucommiae 100g, Radix Dipsaci 100g, Colla Corii Asini 100g, Bulbus Fritillariae Cirrhosae 60g, Fructus Amomi 60g, Folium Artemisiae Argyi 30g, Radix Glycyrrhizae 30g, Radix Scutellariae 100g, ZHIZIREN 100g, Caulis Bambusae In Taenia 60g, Rhizoma Zingiberis Recens 30g, Radix Paeoniae Alba 100g, Rhizoma Polygonati Odorati 60g, Radix Bupleuri 60g, Caulis Perillae 60g.
Concrete preparation method is:
Earlier the Folium Artemisiae Argyi parching to brown being added the 2ml vinegar fries dried; Again Radix Glycyrrhizae is made popular and added Mel 2ml stir-fry to half-dried; At last above-mentioned various Chinese medicine pulverize separately are become 120 order fine powders, according to above-mentioned parts by weight mix homogeneously, in incapsulating, sterilization makes the capsule product.
The present invention can also make plaster according to the practice of pharmacy of routine.
Result of use is better simultaneously with the plaster made in the present invention, and using method is, plaster is attached on the umbilicus, and every subsides were changed in 1～3 day, and every month with 10 days.
Embodiment 2:
Take by weighing raw material by following proportioning:
Radix Angelicae Sinensis 80g, Rhizoma Chuanxiong 80g, Radix Astragali 120g, Rhizoma Atractylodis Macrocephalae 80g, Cornu Cervi Degelatinatum 80g, Semen Cuscutae 80g, Cortex Eucommiae 80g, Radix Dipsaci 80g, Colla Corii Asini 80g, Bulbus Fritillariae Cirrhosae 40g, Fructus Amomi 40g, Folium Artemisiae Argyi 20g, Radix Glycyrrhizae 20g, Radix Scutellariae 80g, ZHIZIREN 80g, Caulis Bambusae In Taenia 40g, Rhizoma Zingiberis Recens 20g, Radix Paeoniae Alba 80g, Rhizoma Polygonati Odorati 40g, Radix Bupleuri 40g, Caulis Perillae 40g.
Concrete preparation method is:
Earlier the Folium Artemisiae Argyi parching to brown being added the 1ml vinegar fries dried; Again Radix Glycyrrhizae is made popular and added Mel 1ml stir-fry to half-dried; At last above-mentioned various Chinese medicines and Folium Artemisiae Argyi Radix Glycyrrhizae mixed powder are broken into 110 order fine powders, according to above-mentioned parts by weight mix homogeneously, in incapsulating, sterilization makes the capsule product.
The present invention can also make plaster according to the practice of pharmacy of routine.
Result of use is better simultaneously with the plaster made in the present invention, and using method is, plaster is attached on the umbilicus, and every subsides were changed in 1～3 day, and every month with 10 days.
Claims (7)
1, a kind of medicine for the treatment of habitual abortion is characterized in that with following parts of medicines by weight be crude drug:
Radix Angelicae Sinensis 8～10, Rhizoma Chuanxiong 8～10, the Radix Astragali 12～15, the Rhizoma Atractylodis Macrocephalae 8～10, Cornu Cervi Degelatinatum 8～10, Semen Cuscutae 8～10, the Cortex Eucommiae 8～10, Radix Dipsaci 8～10, Colla Corii Asini 8～10, Bulbus Fritillariae Cirrhosae 4～6, Fructus Amomi 4～6, Folium Artemisiae Argyi 2～3, Radix Glycyrrhizae 2～3, Radix Scutellariae 8～10, ZHIZIREN 8～10, Caulis Bambusae In Taenia 4～6, Rhizoma Zingiberis Recens 2～3, the Radix Paeoniae Alba 8～10, Rhizoma Polygonati Odorati 4～6, Radix Bupleuri 4～6, Caulis Perillae 4～6.
2, a kind of medicine for the treatment of habitual abortion according to claim 1, wherein the weight proportion of each raw material is:
Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 10, Cornu Cervi Degelatinatum 10, Semen Cuscutae 10, the Cortex Eucommiae 10, Radix Dipsaci 10, Colla Corii Asini 10, Bulbus Fritillariae Cirrhosae 6, Fructus Amomi 6, Folium Artemisiae Argyi 3, Radix Glycyrrhizae 3, Radix Scutellariae 10, ZHIZIREN 10, Caulis Bambusae In Taenia 6, Rhizoma Zingiberis Recens 3, the Radix Paeoniae Alba 10, Rhizoma Polygonati Odorati 6, Radix Bupleuri 6, Caulis Perillae 6.
3, the medicine of treatment habitual abortion according to claim 1 and 2 is characterized in that: described medicament is a said dosage form on any pharmaceutics.
4, the medicine of treatment habitual abortion according to claim 1 and 2 is characterized in that: described medicament is a capsule.
5, the medicine of treatment habitual abortion according to claim 1 and 2 is characterized in that: described medicament is a plaster.
6, the preparation method of the medicine of the described treatment habitual abortion of claim 1 is characterized in that: above-mentioned various Chinese medicine pulverize separately are become 100～120 order fine powders, and according to above-mentioned parts by weight mix homogeneously, in incapsulating, sterilization makes the capsule product.
7, the preparation method of the medicine of the described treatment habitual abortion of claim 1 is characterized in that: with the above-mentioned raw materials medicine, press the method for pharmaceutics routine, also can be made into plaster.
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| CN2009100754192A CN101653590B (en) | 2009-09-14 | 2009-09-14 | Medicine for treating habitual abortion and preparation method thereof |
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| CN2009100754192A CN101653590B (en) | 2009-09-14 | 2009-09-14 | Medicine for treating habitual abortion and preparation method thereof |
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| CN101653590B CN101653590B (en) | 2011-05-11 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068551A (en) * | 2010-11-19 | 2011-05-25 | 宋爱民 | Chinese materia medica preparation for treating habitual abortion |
| CN102600388A (en) * | 2012-03-29 | 2012-07-25 | 常熟市海虞茶叶有限公司 | Traditional Chinese herbal medicine for treating threatened abortion of livestock |
| CN102652767A (en) * | 2011-03-02 | 2012-09-05 | 华中科技大学 | Drug for promoting embryo implantation and preparation method thereof |
| CN102755546A (en) * | 2012-06-28 | 2012-10-31 | 严现坤 | Chinese medicine for treating habitual abortion |
| CN102755413A (en) * | 2012-06-28 | 2012-10-31 | 严现坤 | Chinese medicinal preparation for protecting fetus and consolidating |
| CN103071105A (en) * | 2013-02-06 | 2013-05-01 | 孙迎春 | External traditional Chinese medicinal preparation for treating threatened abortion and preparation method thereof |
| CN105031116A (en) * | 2015-09-07 | 2015-11-11 | 王俊喜 | Traditional Chinese medicine for treating habitual abortion |
| CN105749121A (en) * | 2016-03-29 | 2016-07-13 | 广州暨南生物医药研究开发基地有限公司 | Folium-artemisiae-argyi-containing traditional Chinese medicine preparation for treating habitual abortion and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100571736C (en) * | 2007-04-16 | 2009-12-23 | 北京艺信堂医药研究所 | A kind of Chinese medicine preparation for the treatment of habitual abortion |
-
2009
- 2009-09-14 CN CN2009100754192A patent/CN101653590B/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068551A (en) * | 2010-11-19 | 2011-05-25 | 宋爱民 | Chinese materia medica preparation for treating habitual abortion |
| CN102068551B (en) * | 2010-11-19 | 2012-02-01 | 宋爱民 | Chinese materia medica preparation for treating habitual abortion |
| CN102652767A (en) * | 2011-03-02 | 2012-09-05 | 华中科技大学 | Drug for promoting embryo implantation and preparation method thereof |
| CN102600388A (en) * | 2012-03-29 | 2012-07-25 | 常熟市海虞茶叶有限公司 | Traditional Chinese herbal medicine for treating threatened abortion of livestock |
| CN102600388B (en) * | 2012-03-29 | 2013-12-04 | 太仓市临江农场专业合作社 | Traditional Chinese herbal medicine for treating threatened abortion of livestock |
| CN102755546A (en) * | 2012-06-28 | 2012-10-31 | 严现坤 | Chinese medicine for treating habitual abortion |
| CN102755413A (en) * | 2012-06-28 | 2012-10-31 | 严现坤 | Chinese medicinal preparation for protecting fetus and consolidating |
| CN102755546B (en) * | 2012-06-28 | 2014-02-26 | 严现坤 | Chinese medicine for treating habitual abortion |
| CN103071105A (en) * | 2013-02-06 | 2013-05-01 | 孙迎春 | External traditional Chinese medicinal preparation for treating threatened abortion and preparation method thereof |
| CN103071105B (en) * | 2013-02-06 | 2014-09-03 | 孙迎春 | External traditional Chinese medicinal preparation for treating threatened abortion and preparation method thereof |
| CN105031116A (en) * | 2015-09-07 | 2015-11-11 | 王俊喜 | Traditional Chinese medicine for treating habitual abortion |
| CN105749121A (en) * | 2016-03-29 | 2016-07-13 | 广州暨南生物医药研究开发基地有限公司 | Folium-artemisiae-argyi-containing traditional Chinese medicine preparation for treating habitual abortion and preparation method thereof |
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