CN101573108A - 紫杉醇和白蛋白纳米颗粒联合贝伐单抗对抗癌症 - Google Patents

紫杉醇和白蛋白纳米颗粒联合贝伐单抗对抗癌症 Download PDF

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CN101573108A
CN101573108A CNA2007800490545A CN200780049054A CN101573108A CN 101573108 A CN101573108 A CN 101573108A CN A2007800490545 A CNA2007800490545 A CN A2007800490545A CN 200780049054 A CN200780049054 A CN 200780049054A CN 101573108 A CN101573108 A CN 101573108A
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taxane
effective amount
composition
paclitaxel
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Chinese (zh)
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N·P·德塞
P·孙一雄
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Abraxis Bioscience LLC
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Abraxis Bioscience LLC
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    • A61K9/5169—Proteins, e.g. albumin, gelatin
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04—Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • A—HUMAN NECESSITIES
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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CNA2007800490545A 2006-11-06 2007-11-06 紫杉醇和白蛋白纳米颗粒联合贝伐单抗对抗癌症 Pending CN101573108A (zh)

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CN201510264733.0A CN104940929A (zh) 2006-11-06 2007-11-06 紫杉醇和白蛋白纳米颗粒联合贝伐单抗对抗癌症

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US11/594,417 US20070166388A1 (en) 2005-02-18 2006-11-06 Combinations and modes of administration of therapeutic agents and combination therapy
US11/594,417 2006-11-06

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CN201510264733.0A Pending CN104940929A (zh) 2006-11-06 2007-11-06 紫杉醇和白蛋白纳米颗粒联合贝伐单抗对抗癌症

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US (1) US20070166388A1 (https=)
EP (3) EP3108885A1 (https=)
JP (3) JP5931323B2 (https=)
KR (4) KR20150065957A (https=)
CN (2) CN101573108A (https=)
AU (1) AU2007317859B2 (https=)
BR (1) BRPI0718528A2 (https=)
CA (1) CA2668607A1 (https=)
CY (2) CY1115271T1 (https=)
DK (2) DK2097078T3 (https=)
ES (2) ES2576289T3 (https=)
HU (1) HUE028472T2 (https=)
IL (2) IL198576A (https=)
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NO (1) NO343908B1 (https=)
NZ (1) NZ576856A (https=)
PL (2) PL2481405T3 (https=)
PT (2) PT2481405E (https=)
RU (2) RU2009121568A (https=)
SI (2) SI2481405T1 (https=)
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CN104784121A (zh) * 2010-03-26 2015-07-22 阿布拉科斯生物科学有限公司 治疗肝细胞癌的方法
CN105120859A (zh) * 2013-02-11 2015-12-02 阿布拉科斯生物科学有限公司 治疗黑素瘤的方法
CN105288639A (zh) * 2015-11-23 2016-02-03 中国药科大学 一种载阿霉素的主动靶向白蛋白纳米载体的制备及其应用
CN106310291A (zh) * 2016-09-14 2017-01-11 东南大学 主动靶向抗肿瘤纳米药物及其制备方法和应用
CN108290944A (zh) * 2015-08-18 2018-07-17 梅约医学教育与研究基金会 载体结合剂组合物及其制备和使用方法
CN109922836A (zh) * 2016-08-05 2019-06-21 梅奥医学教育和研究基金会 用于癌症治疗的经修饰抗体-白蛋白纳米颗粒复合物
CN110461311A (zh) * 2016-08-26 2019-11-15 奥野哲治 微细纳米化药剂及其应用
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