CN101531604B - Method for synthesizing betaine - Google Patents

Method for synthesizing betaine Download PDF

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Publication number
CN101531604B
CN101531604B CN2008101570647A CN200810157064A CN101531604B CN 101531604 B CN101531604 B CN 101531604B CN 2008101570647 A CN2008101570647 A CN 2008101570647A CN 200810157064 A CN200810157064 A CN 200810157064A CN 101531604 B CN101531604 B CN 101531604B
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China
Prior art keywords
controlled
acetic acid
mono chloro
chloro acetic
amination
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CN2008101570647A
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CN101531604A (en
Inventor
邹三元
王俊耀
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TIANSHI FODDER CO Ltd YIXING CITY
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TIANSHI FODDER CO Ltd YIXING CITY
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Abstract

The invention relates to a method for synthesizing betaine, which is characterized in that the method uses trimethylamine and chloroacetic magnesium at the molar ratio of 1.02-1.03:1 for amination and synthesis; the reaction temperature of synthesis is controlled between 40 and 60 DEGC; the optimum reaction temperature is controlled between 53 and 55 DEG C; a pH value is controlled to be between 8 and 9; synthesis time is between 2.5 and 5 hours; continuous feeding and continuous discharging are adopted; and the feeding and discharging of reaction are regulated and controlled by use of a pH meter. The method has the advantages of eliminating frequent operation for feeding, synthesis and discharging during batch production, as well as unsafe factors possibly caused by the frequent operation, increasing production yield, treating and recycling water after the concentration of betaine solution and reducing the waste of freshwater resources.

Description

A kind of method of synthesizing betaine
Technical field
The present invention relates to a kind of method of synthesizing betaine.
Technical background
Trimethyl-glycine is to use a kind of widely additive at present, is applied in aspects such as feed, food, makeup, medicine, is that employing sodium chloroacetate, Trimethylamine 99 are that raw material carries out the synthetic trimethyl-glycine, and process flow sheet is seen Fig. 1.This technology exists following deficiency: 1) batch production, and the charging of production process, synthetic, the frequent operation of blowing yield poorly, plant factor is low, safe handling process holding time is many, possibly cause unsafe factor because of frequent operation in addition; 2) sodium-chlor that comes out through concentrating and separating of reaction solution is difficult to carry out industrial utilization, and production technique water does not make full use of, and production cost is high, the equipment blowing, and charging emptying causes environmental pollution.
Summary of the invention
The present invention is just in order to overcome above-mentioned deficiency, and providing a kind of is the method for raw material synthesizing betaine with Mono Chloro Acetic Acid magnesium, Trimethylamine 99, and it can continuous production, and plant factor is high, and waste of raw materials is few, and water resources can rationally make full use of.Specifically implement like this: a kind of method of synthesizing betaine; It is characterized in that using mol ratio synthetic as Trimethylamine 99 and the amination of Mono Chloro Acetic Acid magnesium of 1.02-1.03:1; Synthesis reaction temperature is controlled at 40-60 ℃; The reaction optimum temps is controlled at 53-55 ℃, and pH value is controlled to be 8-9, and generated time is 2.5-5 hour.
The present invention adopts the continuous production method; Be communicated with by reaction tower, amination still, amination liquid recycle pump, trimethyl-glycine storage tank pipeline successively; Be equipped with the feed-pipe of Trimethylamine 99 and Mono Chloro Acetic Acid magnesium on the reaction tower respectively; The amination liquid recycle pump inserts reaction tower after being communicated with condensing surface by circulating line, and the PH meter is installed on the described circulating line.Carry out continuous detecting through the meter of the PH on the circulating line and control the input and output material amount, material reacts in reaction tower, and reacted material gets into reaction kettle, carries out external forced circulation and cooling through recycle pump then, removes reaction heat, obtains the ideal transformation efficiency.
The Mono Chloro Acetic Acid magnesium that the present invention adopts is by in Mono Chloro Acetic Acid, the magnesiumcarbonate and generate, and the neutralization reaction controlled temperature is 25-40 ℃ in the Mono Chloro Acetic Acid magnesium neutralizing well.
When amination liquid in the trimethyl-glycine storage tank reach a certain amount of after, amination liquid concentrated get final product, the phlegma that obtains when concentrating amination liquid cools off, water coolant is transported to Mono Chloro Acetic Acid magnesium neutralizing well, magnesium chloride can be used as additive for farm animal feed.
The present invention adopts continuously feeding and discharging continuously; React the adjusting control of input and output material with the PH meter; The unsafe factor of having eliminated the frequent operation of charging at batch production process, synthetic, blowing and possibly having caused because of frequent operation, and improved production output; Water after alkali solution of beet concentrates recycles through handling, and has reduced the waste of Freshwater resources.Concrete advantage is:
1, plant factor improves 40%;
2, utilization rate of raw materials improves, 300 yuan/ton of cost savings;
3, the process water saving, per ton 60% aqua is practiced thrift 600 kilograms in tap water;
4, the factory utilization ratio is high, and the workman is simple to operate;
5, magnesium chloride can be used as additive for farm animal feed;
6, the technology three-waste pollution significantly reduces.
Description of drawings
Fig. 1 is the background process flow sheet.
Fig. 2 is a process flow sheet of the present invention
Embodiment
Embodiment 1; A kind of method of synthesizing betaine uses mol ratio synthetic as Trimethylamine 99 and the amination of Mono Chloro Acetic Acid magnesium of 1.02:1, and synthesis reaction temperature is controlled at 53 ℃; PH value is controlled to be 8.5; Generated time is 3 hours, and wherein Mono Chloro Acetic Acid magnesium is by in Mono Chloro Acetic Acid, the magnesiumcarbonate and generate, and the neutralization reaction temperature is controlled to be 40 ℃
Embodiment 2; A kind of method of synthesizing betaine; Adopt the continuous production method, be communicated with, be equipped with the feed-pipe of Trimethylamine 99 and Mono Chloro Acetic Acid magnesium on the reaction tower respectively by reaction tower, amination still, amination liquid recycle pump, trimethyl-glycine storage tank pipeline successively; The amination liquid recycle pump inserts reaction tower after being communicated with condensing surface by circulating line, and the PH meter is installed on the described circulating line.
Use mol ratio synthetic as Trimethylamine 99 and the amination of Mono Chloro Acetic Acid magnesium of 1.03:1; Synthesis reaction temperature is controlled at 55 ℃, and pH value is controlled to be 8.5, and generated time is 2.5 hours; Wherein Mono Chloro Acetic Acid magnesium is by in Mono Chloro Acetic Acid, the magnesiumcarbonate and generate, and the temperature of neutralization reaction is controlled to be 30 ℃ in the neutralizing well
Embodiment 3, reference implementation example 2, and the mol ratio of Trimethylamine 99 and Mono Chloro Acetic Acid magnesium is 1.025:1; Synthesis reaction temperature is controlled at 40 ℃, and pH value is controlled to be 8, and generated time is 4 hours; In Mono Chloro Acetic Acid, the magnesiumcarbonate and generate Mono Chloro Acetic Acid magnesium, the temperature of the reaction of neutralizing well is controlled to be 25 ℃
Embodiment 4, reference implementation example 2, and the mol ratio of Trimethylamine 99 and Mono Chloro Acetic Acid magnesium is 1.03:1; Synthesis reaction temperature is controlled at 60 ℃, and pH value is controlled to be 9, and generated time is 5 hours; In Mono Chloro Acetic Acid, the magnesiumcarbonate and generate Mono Chloro Acetic Acid magnesium, the temperature of the reaction of neutralizing well is controlled to be 28 ℃

Claims (4)

1. the method for a synthesizing betaine is characterized in that using mol ratio to be 1.02-1.03: 1 Trimethylamine 99 and the amination of Mono Chloro Acetic Acid magnesium are synthetic, and synthesis reaction temperature is controlled at 40-60 ℃, and the pH value is controlled to be 8-9, and generated time is 2.5-5 hour; Adopt the continuous production method; Be communicated with by reaction tower, amination still, amination liquid recycle pump, trimethyl-glycine storage tank pipeline successively; Be equipped with the feed-pipe of Trimethylamine 99 and Mono Chloro Acetic Acid magnesium on the reaction tower respectively; The amination liquid recycle pump inserts reaction tower after being communicated with condensing surface by circulating line, on the described circulating line pH meter is installed.
2. the method for synthesizing betaine according to claim 1 is characterized in that synthesis reaction temperature is controlled at 53-55 ℃.
3. the method for synthesizing betaine according to claim 1 and 2 is characterized in that Mono Chloro Acetic Acid magnesium is by in Mono Chloro Acetic Acid, the magnesiumcarbonate and generate.
4. the method for synthesizing betaine according to claim 3 is characterized in that Mono Chloro Acetic Acid magnesium carries out in neutralizing well, and reaction control temperature is 25-40 ℃.
CN2008101570647A 2008-09-23 2008-09-23 Method for synthesizing betaine Active CN101531604B (en)

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Application Number Priority Date Filing Date Title
CN2008101570647A CN101531604B (en) 2008-09-23 2008-09-23 Method for synthesizing betaine

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CN101531604B true CN101531604B (en) 2012-02-22

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102126964A (en) * 2010-12-10 2011-07-20 江南大学 Method for preparing high-content alpha-lauryl betaine by solvent-free quaternization
CN105130830B (en) * 2015-09-14 2017-02-01 宜兴市天石饲料有限公司 Preparation method of betaine
CN109134288A (en) * 2018-08-29 2019-01-04 宜兴市天石饲料有限公司 A kind of device and method of synthesizing betaine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681972A (en) * 1994-04-12 1997-10-28 Witco Surfactants Gmbh Process for preparing highly concentrated, free-flowing aqueous solutions of betaines
CN1165813A (en) * 1996-10-16 1997-11-26 中国农业科学院饲料研究所 Synthetic process for betaine as fodder additive

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681972A (en) * 1994-04-12 1997-10-28 Witco Surfactants Gmbh Process for preparing highly concentrated, free-flowing aqueous solutions of betaines
CN1165813A (en) * 1996-10-16 1997-11-26 中国农业科学院饲料研究所 Synthetic process for betaine as fodder additive

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨官娥等.甜菜碱合成新工艺的研究.《中国药物化学杂志》.2001,第11卷(第3期),第160-162页. *

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