CN101511264A - 超极化方法、系统和组合物 - Google Patents

超极化方法、系统和组合物 Download PDF

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Publication number
CN101511264A
CN101511264A CNA2007800114443A CN200780011444A CN101511264A CN 101511264 A CN101511264 A CN 101511264A CN A2007800114443 A CNA2007800114443 A CN A2007800114443A CN 200780011444 A CN200780011444 A CN 200780011444A CN 101511264 A CN101511264 A CN 101511264A
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China
Prior art keywords
hyperpolarization
solvent
hyperpolarized
medium
described method
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English (en)
Chinese (zh)
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阿夫鲁姆·贝尔策
尼尔·卡莱肖弗斯凯
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MILLIKELVIN TECHNOLOGIES LLC
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MILLIKELVIN TECHNOLOGIES LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
CNA2007800114443A 2006-02-21 2007-02-21 超极化方法、系统和组合物 Pending CN101511264A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77519606P 2006-02-21 2006-02-21
US60/775,196 2006-02-21
US80269906P 2006-05-23 2006-05-23
US60/802,699 2006-05-23
PCT/US2007/004654 WO2007136439A2 (en) 2006-02-21 2007-02-21 Hyperpolarization methods, systems and compositions

Publications (1)

Publication Number Publication Date
CN101511264A true CN101511264A (zh) 2009-08-19

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CNA2007800114443A Pending CN101511264A (zh) 2006-02-21 2007-02-21 超极化方法、系统和组合物

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US (2) US20090016964A1 (https=)
EP (1) EP1986702A4 (https=)
JP (1) JP2009527768A (https=)
KR (2) KR101095943B1 (https=)
CN (1) CN101511264A (https=)
AU (1) AU2007254464B2 (https=)
CA (1) CA2643306C (https=)
WO (1) WO2007136439A2 (https=)

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CN102762996A (zh) * 2010-02-16 2012-10-31 皇家飞利浦电子股份有限公司 利用被赋予轨道角动量的光的光学超极化
CN105358999A (zh) * 2013-05-03 2016-02-24 量子谷投资基金有限合伙公司 使用腔使自旋系综极化
CN111537540A (zh) * 2020-05-18 2020-08-14 中国科学院精密测量科学与技术创新研究院 一种用于低磁场下仲氢诱导极化装置及方法
CN111971569A (zh) * 2018-02-19 2020-11-20 布鲁克法国股份公司 多孔基质中的核自旋超极化
CN119086618A (zh) * 2023-09-06 2024-12-06 中国科学院精密测量科学与技术创新研究院 用于超极化129Xe磁共振分子探针流动采样的装置及方法

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WO2007136439A2 (en) 2006-02-21 2007-11-29 Avrum Belzer Hyperpolarization methods, systems and compositions
US20170269180A1 (en) * 2006-02-21 2017-09-21 Millikelvin Technologies Llc Systems and related methods for rapidly moving materials into and out of a cryogenic environment
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DE212010000123U1 (de) * 2009-08-26 2012-09-13 Aspect Magnet Technologies Ltd. Mittel zur Durchführung einer Bildgebung mit hyperpolarisiertem Gas
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US20150234105A1 (en) * 2012-06-29 2015-08-20 Eduardo Andres Larrain Sanchez System that can be used to polarise glass, acrylic and similar automatically as required by the user
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US9404984B2 (en) * 2012-11-06 2016-08-02 Bruker Uk Limited Method of hyperpolarization applying brute force using particulate acceleration agents
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US11926525B2 (en) 2015-09-07 2024-03-12 The University Of Nottingham Production of hyperpolarized gas
JP6592405B2 (ja) * 2016-06-10 2019-10-16 日本電信電話株式会社 熱可塑性ポリエステルの延性低下による寿命の推定方法
EP3544591B1 (en) * 2016-11-23 2022-04-20 Mayo Foundation for Medical Education and Research Particle-mediated delivery of biologics
GB201703658D0 (en) * 2017-03-07 2017-04-19 Univ York Hyperpolarization in aqueous media via SABRE
CN108627532B (zh) * 2017-03-23 2020-10-16 中国科学院大连化学物理研究所 一种用于原位核磁共振检测甲烷和水吸附状态的装置及方法
WO2019071090A1 (en) * 2017-10-06 2019-04-11 University Of Florida Research Foundation METHODS AND SYSTEMS FOR PRODUCTION, USE, AND ADMINISTRATION OF HYPERPOLARIZED FLUIDS
FR3074302B1 (fr) * 2017-11-28 2019-11-22 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procede et appareil d'hyperpolarisation de spins, notamment electroniques
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WO2020178310A1 (en) 2019-03-04 2020-09-10 Danmarks Tekniske Universitet Cleaning of a fluid path system for hyperpolarization of a pharmaceutical product
EP4256357A1 (en) * 2020-12-07 2023-10-11 NVision Imaging Technologies GmbH Systems and methods for generation of hyperpolarized compounds using parahydrogen
EP4285131A2 (en) * 2021-01-30 2023-12-06 NVision Imaging Technologies GmbH Systems and methods for generation of hyperpolarized materials
US12409239B2 (en) 2021-06-25 2025-09-09 Beacon Mri Ltd Particles for use in hyperpolarization
WO2025111525A1 (en) * 2023-11-22 2025-05-30 University Of Wyoming Apparatus and methods for magnetically assisted alteration or transformation of organic substances
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102762996A (zh) * 2010-02-16 2012-10-31 皇家飞利浦电子股份有限公司 利用被赋予轨道角动量的光的光学超极化
CN102762996B (zh) * 2010-02-16 2016-08-03 皇家飞利浦电子股份有限公司 利用被赋予轨道角动量的光的光学超极化
CN105358999A (zh) * 2013-05-03 2016-02-24 量子谷投资基金有限合伙公司 使用腔使自旋系综极化
CN111971569A (zh) * 2018-02-19 2020-11-20 布鲁克法国股份公司 多孔基质中的核自旋超极化
CN111971569B (zh) * 2018-02-19 2023-04-25 布鲁克法国股份公司 多孔基质中的核自旋超极化
CN111537540A (zh) * 2020-05-18 2020-08-14 中国科学院精密测量科学与技术创新研究院 一种用于低磁场下仲氢诱导极化装置及方法
CN119086618A (zh) * 2023-09-06 2024-12-06 中国科学院精密测量科学与技术创新研究院 用于超极化129Xe磁共振分子探针流动采样的装置及方法

Also Published As

Publication number Publication date
AU2007254464B2 (en) 2013-02-21
WO2007136439A3 (en) 2008-10-23
KR101095943B1 (ko) 2011-12-19
US8703201B2 (en) 2014-04-22
KR20080096840A (ko) 2008-11-03
JP2009527768A (ja) 2009-07-30
US20090016964A1 (en) 2009-01-15
AU2007254464A1 (en) 2007-11-29
CA2643306C (en) 2016-05-03
WO2007136439A2 (en) 2007-11-29
KR101321862B1 (ko) 2013-10-28
KR20080091402A (ko) 2008-10-10
EP1986702A2 (en) 2008-11-05
CA2643306A1 (en) 2007-11-29
US20120114851A1 (en) 2012-05-10
EP1986702A4 (en) 2012-12-12

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Application publication date: 20090819