CN101450060A - Soluble powder for treating livestock and poultry coccidiosis - Google Patents
Soluble powder for treating livestock and poultry coccidiosis Download PDFInfo
- Publication number
- CN101450060A CN101450060A CNA2007101505677A CN200710150567A CN101450060A CN 101450060 A CN101450060 A CN 101450060A CN A2007101505677 A CNA2007101505677 A CN A2007101505677A CN 200710150567 A CN200710150567 A CN 200710150567A CN 101450060 A CN101450060 A CN 101450060A
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- coccidiosis
- soluble powder
- poultry
- prinzone
- squibb
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Abstract
The invention relates to a soluble powder for treating livestock and poultry coccidiosis, comprising sulfachlorpyridazine sodium, sulfachlorpyridazine sodium and auxiliary materials. The medicament of the invention has positive effect for treating livestock and poultry coccidiosis and can be suitable for popularization and application. In the invention, the sulfachlorpyridazine sodium and the sulfachlorpyridazine sodium are compatible with each other for using and generating cooperating effect, the invention can be acted on different periods of coccidia growth, can kill ova and imago simultaneously, can effectively treat the coccidiosis, has good oral administration absorption effect and high safety.
Description
Technical field
The invention belongs to field of veterinary, particularly relate to a kind of soluble powder that is used for the treatment of coccidiosis of livestock and poultry.
Background technology
Coccidiosis is the parasitic disease that poultry are common and harm is very serious, it also is a kind of common acute popular protozoacide, coccidiosis with chicken is an example: show as spirit tired, drowsiness, by Mao Songluan, close the order drop-head, slow-witted upright hang wing, like crowded together, crop speak in a low voice full of liquid, the dysentery of having blood in stool, the crissum feather is because of manure contamination adhesion, happiness drink or go on a hunger strike.Visual mucosa, hat, whisker are pale.Disease spiritedness symptom in latter stage, stupor, bipod turns up, stiff or spasm.This sick the distribution extensively taken place generally, and be maximum to chickling harm.With the easy infection of the chicken of 15-50 ages in days, temperature is the most popular more season at 20-30 ℃ and rainwater.Sickness rate is up to about 70%, and mortality rate 20-50% does not wait.Suffer from how more back poor growth of chicken, deficiency in economic performance.As untimely control, often cause bigger economic loss to the raiser,
Current control to chicken coccidiosis mainly relies on medicine, and the medicine of use has chemical synthetic drug and antibiotic two classes.Yet long-term a large amount of a kind of antibiotics that uses has not only formed more drug residue in the poultry body, also caused the generation of a large amount of drug-resistant bacterias simultaneously, has had a strong impact on medicine therapeutic effect in vivo.
Summary of the invention
Based on above-mentioned situation, the object of the present invention is to provide a kind of soluble powder that is used for the treatment of coccidiosis of livestock and poultry
The object of the present invention is achieved like this: represent to be respectively sulfaclozine sodium 7%-8% with percentage by weight, Prinzone (Squibb) 7%-8%, adjuvant 84%-86%.
Described adjuvant comprises: anhydrous glucose, oral glucose etc. are preferably anhydrous glucose.
In order to obtain better effect, preferred ingredient is: sulfaclozine sodium 7.5%, Prinzone (Squibb) 7.5%, adjuvant 85%.
The present invention can adopt the general process of industry, equipment preparation.The following method preparation of preferred employing comprises step:
Earlier sulfaclozine sodium, Prinzone (Squibb) are pulverized with used adjuvant, pulverized back mistake 60 mesh sieves; The adjuvant of getting sulfaclozine sodium, Prinzone (Squibb) and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly.
Sulfaclozine sodium: be sulfa drugs, with para-amino benzoic acid competition dihydrofolate synthetase and tetrahydrofolic acid synzyme, hinder dihydrofoilic acid synthetic synthetic with tetrahydrofolic acid, finally influence the synthetic of nucleoprotein, thereby the growth and breeding that suppresses antibacterial and coccidiosis, oral absorption is rapid, acts on the asexual propagation phase of coccidiosis, suppresses the secondary schizont and grows.
Prinzone (Squibb): antimicrobial spectrum is similar to sulfamonomethoxine, and most of gram positive bacterias and negative bacterium are all had stronger inhibitory action, and it is slower that antibacterial produces drug resistance to this medicine.Be mainly used in the caused various diseases of sensitive organism, pig toxoplasmosis, bowel oedema disease, fowl, rabbit coccidiosis are had curative effect preferably.
In order to verify the therapeutic effect of medicine of the present invention, get medicine of the present invention and do the clinical efficacy test at Jinghai county chicken house.Get the chicken that suffers from coccidiosis, use medicine of the present invention to treat initial dose: add medicine 1.0g of the present invention in per 1 premium on currency, freely drank water 1 day; Maintenance dose: add medicine 1.0g of the present invention in per 3 premium on currency, logotype 5 days was a course of treatment.Most ofly after the course of treatment suffer from chicken and cured, clinical symptom disappearance or effectively alleviated, effective percentage all reaches more than 90%.
Beneficial effect: by clinical trial as can be seen, medicine of the present invention curative effect aspect treatment treatment coccidiosis of livestock and poultry is certain, is suitable for applying in herding is produced.The present invention fills a prescription and adopts Prinzone (Squibb) and two kinds of compatibility of drugss of sulfaclozine sodium to use, and can produce synergism, acts on the different times of coccidiosis growth, simultaneously killing ova and adult, effectively reach the purpose of treatment coccidiosis, oral absorption is good, has higher safety.
The specific embodiment
Embodiment 1: earlier sulfaclozine sodium 70g, Prinzone (Squibb) 70g and used adjuvant anhydrous glucose 860g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting sulfaclozine sodium, Prinzone (Squibb) and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of soluble powder, wherein contain sulfaclozine sodium 70g, Prinzone (Squibb) 70g.
Anticoccidial drug.Be mainly used in the coccidiosis of poultry, the treatment when being particularly suitable for the coccidiosis outburst.Usage and dosage: initial dose: add medicine 1.1g of the present invention in per 1 premium on currency, freely drank water 1 day; Maintenance dose: add medicine 1.1g of the present invention in per 3 premium on currency, logotype 3-5 days is a course of treatment.
Embodiment 2: earlier sulfaclozine sodium 75g, Prinzone (Squibb) 75g and used adjuvant anhydrous glucose 850g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting sulfaclozine sodium, Prinzone (Squibb) and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of soluble powder, wherein contain sulfaclozine sodium 75g, Prinzone (Squibb) 75g.
Anticoccidial drug.Be mainly used in the coccidiosis of poultry, the treatment when being particularly suitable for the coccidiosis outburst.Usage and dosage: initial dose: add medicine 1.0g of the present invention in per 1 premium on currency, freely drank water 1 day; Maintenance dose: add medicine 1.0g of the present invention in per 3 premium on currency, logotype 3-5 days is a course of treatment.
Embodiment 3: earlier sulfaclozine sodium 80g, Prinzone (Squibb) 80g and used adjuvant anhydrous glucose 840g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting sulfaclozine sodium, Prinzone (Squibb) and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get soluble powder pact, 1000g, wherein contain sulfaclozine sodium 80g, Prinzone (Squibb) 80g.
Anticoccidial drug.Be mainly used in the coccidiosis of poultry, the treatment when being particularly suitable for the coccidiosis outburst.Usage and dosage: initial dose: add medicine 0.9g of the present invention in per 1 premium on currency, freely drank water 1 day; Maintenance dose: add medicine 0.9g of the present invention in per 3 premium on currency, logotype 3-5 days is a course of treatment.
Claims (3)
1, a kind of soluble powder that is used for the treatment of coccidiosis of livestock and poultry is characterized in that the medicine that medicine of the present invention comprises is: sulfaclozine sodium, Prinzone (Squibb), adjuvant.
2, a kind of soluble powder that is used for the treatment of coccidiosis of livestock and poultry according to claim 1, it is characterized in that: represent to be respectively sulfaclozine sodium 7%-8% with percentage by weight, Prinzone (Squibb) 7%-8%, adjuvant 84%-86%, described adjuvant comprises: anhydrous glucose, oral glucose etc. are preferably anhydrous glucose.
3, a kind of soluble powder that is used for the treatment of coccidiosis of livestock and poultry according to claim 1, it is characterized in that: preferred ingredient is: sulfaclozine sodium 7.5%, Prinzone (Squibb) 7.5%, adjuvant 85%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101505677A CN101450060A (en) | 2007-11-29 | 2007-11-29 | Soluble powder for treating livestock and poultry coccidiosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101505677A CN101450060A (en) | 2007-11-29 | 2007-11-29 | Soluble powder for treating livestock and poultry coccidiosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101450060A true CN101450060A (en) | 2009-06-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101505677A Pending CN101450060A (en) | 2007-11-29 | 2007-11-29 | Soluble powder for treating livestock and poultry coccidiosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101450060A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267148A (en) * | 2015-11-11 | 2016-01-27 | 郑州后羿制药有限公司 | Dissolvable sulfachloropyrazine sodium powder and preparation method thereof |
-
2007
- 2007-11-29 CN CNA2007101505677A patent/CN101450060A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267148A (en) * | 2015-11-11 | 2016-01-27 | 郑州后羿制药有限公司 | Dissolvable sulfachloropyrazine sodium powder and preparation method thereof |
| CN105267148B (en) * | 2015-11-11 | 2018-06-22 | 河南后羿实业集团有限公司 | A kind of sulfaclozine soluble powder and preparation method thereof |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090610 |