CN101417021B - External traditional Chinese medicine for giving up drug habits and preparation method - Google Patents

External traditional Chinese medicine for giving up drug habits and preparation method Download PDF

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CN101417021B
CN101417021B CN2008102271873A CN200810227187A CN101417021B CN 101417021 B CN101417021 B CN 101417021B CN 2008102271873 A CN2008102271873 A CN 2008102271873A CN 200810227187 A CN200810227187 A CN 200810227187A CN 101417021 B CN101417021 B CN 101417021B
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张财
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张财
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Abstract

The invention relates to an external-use Chinese medicament for fighting drugs, which comprises a main medicine and an adjuvant; the raw materials of the main medicine comprise the following crude medicines according to parts by weight: 1pbw to 15pbw of scorpion, 8pbw to 40pbw of radix aconiti agrestis, 20pbw to 50pbw of aconitum Chinese paxton, 25pbw to 40pbw of gecko, 15pbw to 30pbw of nux vomica, 40pbw to 80pbw of bloodsuckers, 35pbw to 90pbw of Chinese gall, 35pbw to 90pbw of radices euphorbiae kansui liou, 8pbw to 30pbw of brimstone, 3pbw to 25pbw of cantharis, 2pbw to 8pbw of borneol (borneolum syntheticum), 1pbw to 5pbw of camphor, 10pbw to 90pbw of dung beetles, 4pbw to 28pbw of musk and 250pbw to 500pbw of Sailong bone; the raw materials of the adjuvant comprise 15pbw to 20pbw offlos daturae, 8pbw to 12pbw of liquorice, 15pbw to 20pbw of safflower and 300pbw to 800pbw of Shanxi mature vinegar. The invention also relates to a preparation method of the external-use Chinese medicament. The external-use Chinese medicament is applied to the projection position of encephalic conarium inside in the occipital skin of a patient, utilizes the principles of using poison as an antidote to poison and removing toxin by normalizing meridian to help the patient withdraw addicting to narcotic drugs, such as heroin, methamphetamine, marijuana or dancing outreach, and the like.

Description

A kind of drug rehabilitation external Chinese medicine and preparation method thereof
Technical field
The present invention relates to a kind of external Chinese medicine, especially relate to a kind of external Chinese medicine that is used to rehabilitate addicts and its production and application.
Background technology
The harm of drugs has become global problem.The infringement that addiction that human body produces drugs and dependency impel the smoker to accept drugs without end but can't be extricated oneself.Human body is rehabilitated addicts becomes the focus and the difficult point of medical domain research day by day.At present, doctor trained in Western medicine drug rehabilitation method is costly, cause the secondary addiction easily, and do not obtain significant effect all the time, and relapse rate is high.Research to the detoxification by Chinese medicine method is also relatively extensive at present, many Chinese medicine preparation are provided for drug rehabilitation, but wherein in the majority with oral drugs and injection, this class need all can cause in various degree damage to gastrointestinal tract mucous and blood vessel by digestion and the preparation of blood circulation administration.
New result of study to drug addiction shows that drug addiction is to concentrate on due to the pineal harmful microorganism flora of human body intracranial.Under this background, the present invention proposes a kind of external Chinese medicine that is used to quit drug abuse, and directly acts on pinus, overcomes the drawback in the above-mentioned drug addiction treatment when strengthening drug abstinence.
Summary of the invention
The objective of the invention is to: a kind of external Chinese medicine against drug dependence is provided, make its mode effectively give up the addiction of human body, overcome drawback and limitation that operation in the existing drug rehabilitation method, oral formulations and injection etc. bring drugs such as heroin, methamphetamine hydrochloride, Fructus Cannabis or head-shaking pill with external application.
The objective of the invention is to be achieved through the following technical solutions:
A kind of drug rehabilitation external Chinese medicine is provided, comprises principal agent and auxiliary medicine, the weight ratio of principal agent and auxiliary medicine is 3~4:6~7, and wherein principal agent is prepared by the crude drug of following parts by weight:
Scorpio 1~15 Radix Aconiti Kusnezoffii 8~40 Radix Aconitis 20~50 Gekko Swinhonis 25~40
Semen Strychni 15~30 Hirudos 40~80 Galla Chinensiss 35~90 Radix Kansuis 35~90
Sulfur 8~30 Mylabris, 3~25 Borneolum Syntheticums (borneolum syntheticum) 2~8
Camphora 1~5 Catharsii molossi 10~90 Moschus 4~28 Bailey Myospalax Born 250~500.
Described principal agent is preferably prepared by the crude drug of following parts by weight:
Scorpio 7~9 Radix Aconiti Kusnezoffii 8~23 Radix Aconitis 20~25 Gekko Swinhonis 25~29
Semen Strychni 17~20 Hirudos 13~64 Galla Chinensiss 55~65 Radix Kansuis 55~65
Sulfur 7~14 Mylabris, 6~7 Borneolum Syntheticums (borneolum syntheticum) 4~6
Camphora 3~5 Catharsii molossis 22~27 Moschus 6~7 Bailey Myospalax Born 300~450.
Described Bailey Myospalax Born can substitute with Os Tigris.
Described auxiliary medicine is an excipient, and its raw material comprises: the Shanxi mature vinegar of Flos Daturae 15~20 weight portions, Radix Glycyrrhizae 8~12 weight portions, Flos Carthami 15~20 weight portions and 300~800 parts by weight.
Described excipient material preferably includes: the Shanxi mature vinegar of Flos Daturae 17 weight portions, Radix Glycyrrhizae 10 weight portions, Flos Carthami 17 weight portions and 500 parts by weight.
The present invention also provides a kind of described drug rehabilitation external preparation method of Chinese medicine, may further comprise the steps:
(1) preparation principal agent: 15 kinds of crude drug pulverize separately of described ratio are become fine powder, and remix evenly back is standby;
(2) the preparation auxiliary medicine is an excipient:
1) Flos Daturae of 15~20 weight portions, the Radix Glycyrrhizae of 8~12 weight portions and the Flos Carthami pulverize separately of 15~20 weight portions are become fine powder;
2) fine powder that step 1) is prepared adds the Shanxi mature vinegar slow fire boiling of 300~800 weight portions, until volume half;
(3) excipient of principal agent that step (1) is prepared and step (2) preparation promptly obtains described external Chinese medicine against drug dependence according to the weight ratio mix homogeneously of 3~4:6~7.
Step (1) and (2) described pulverizing are with 800 order pulverizers described crude drug to be processed into fine powder.
The weight ratio that is mixed of described principal agent of step (3) and excipient is preferably 4:6 or 3:7.
The present invention also provides described drug rehabilitation external Chinese medicine giving up human body to the application aspect the addiction of drugs such as heroin, methamphetamine hydrochloride, Fructus Cannabis or head-shaking pill.
When external Chinese medicine of the present invention is used, spread on the projected position of intracranial pinus outward at patient's occipitalia skin, by scalp grandson network and intracranial meridians UNICOM channel, make the efficacy of a drug infiltrate harmful microorganism flora survival position, the principle of utilizing treating the poisonous disease with poisonous drugs, collateral dredging to draw out pus by applying a plaster to the affected part, kill the harmful microorganism flora of former of drug addiction and excrete, help the patient to rehabilitate addicts.In the medicine of the present invention:
Scorpio, Gekko Swinhonis, Borneolum Syntheticum, Catharsii molossi and sulfur have the effect of setting upright.Scorpio poison biological nerve connections capable of blocking wherein; Gekko Swinhonis can be anaesthetized toxicity microorganism species in the human body, its biological activity is gone down or losss.
Radix Aconiti Kusnezoffii, Radix Aconiti, Galla Chinensis, Semen Strychni, Bailey Myospalax Born (or Os Tigris) have eliminating evil effect.But Bailey Myospalax Born removing obstruction in the collateral to relieve pain wherein; Radix Aconiti Kusnezoffii, Radix Aconiti are share and can suppress the drug addiction generation; Semen Strychni, Galla Chinensis effect and Radix Aconiti, Radix Aconiti Kusnezoffii are similar.
Hirudo, Mylabris and Moschus function of dominant medicine can promote the performance of drug effect.Wherein the effect of Moschus is to impel medicine to infiltrate and arrives focus, and the effect of Hirudo and Mylabris is to promote the discharge of toxin.
In the pharmaceutical formulation of the present invention, " Sialon " of Bailey Myospalax Born is the Tibetan language transliteration, the formal name used at school Myospalax baileyi.Myospalax baileyi is lived in 2800 meters of height above sea level to 4300 high and cold meadow, all the year round in underground life, and dark 2 meters to 2.5 meters of cave, overhead about 30 centimetres of active tunnel, the rhizome that specially pastures, solitary life, copulation in April, 9 monthly output.The vital stage of Myospalax baileyi had only about 3 years.
Nineteen ninety, Bailey Myospalax Born is " the new medical material of a national class animal " by national official approval, and this is first " a class animal drug " that the medical authorities of China authority approval is since the establishment of the nation assert.
Bailey Myospalax Born nature and flavor " hot salty, tepor is returned liver, kidney channel ".Function cures mainly: have dispel the wind, the effect of cold expelling, dehumidifying, removing obstruction in the collateral to relieve pain, liver and kidney tonifying, be used for diseases such as limbs joint pain and swelling that anemofrigid-damp arthralgia causes, joint stuffiness, numbness of the skin, soreness of the waist and knees.Studies have shown that Bailey Myospalax Born and Os Tigris have similar flavor efficacy.Its main chemical compositions and drug effect are extremely similar to Os Tigris.
Quality standard:
Adopted name: Bailey Myospalax Born
The Chinese phonetic alphabet: sai long gu
Standard No.: WS-207 (Z-46)-90
Character:
Skull is flat and wide, and is slightly triangular in shape; Nasal bone is longer, and end is not the blunted cone shape, two nasal bone leading edge comissures are recessed incise shallow; Cheekbone is interior to outer expansion; Two top ridges are not joined forwardly mutually; The pillow back rigidity is strong, and the pillow median ridge is undeveloped; Incisive foramen is little, the downward encirclement incisive foramen of premaxilla; Upper jaw bone has front tooth a pair of, three pairs on no canine tooth molar.Stretch lobule behind the normal tool one of third molar, mandibular bone also has front tooth a pair of, and last front tooth is big, is the cutter shape.Function with cure mainly:
Functions dispelling wind and clearing away cold, removing dampness, removing obstruction in the collateral to relieve pain, liver and kidney tonifying, and the limbs joint pain, swelling, the joint stuffiness that cause in anemofrigid-damp arthralgia, numbness of the skin, the waist urushic acid is soft.
The using method of Chinese medicine of the present invention:
Match with hospital gauze, surgical membrane and adhesive plaster, with cataplasm of tcm of the present invention limitation and fixedly stick on the projected position of intracranial pinus in patient's occipitalia skin.Complete 7 days courses of treatment, paste every subsides 20-30g every day 1.
Compared with prior art, external Chinese medicine of the present invention has following beneficial effect:
1. new result of study shows that drug addiction is to concentrate on due to the pineal harmful microorganism flora of intracranial, and therefore the harmful microorganism flora at pinus place being treated targetedly is best policy.Operation method under this treatment policy not only the expense costliness, for the patient brings wound and misery, and have high risk.And equally just can make the concentrated pinus place that acts on of medicine based on the external Chinese medicine of the present invention of this treatment policy method by external application, the principle of utilizing Chinese medicine treating the poisonous disease with poisonous drugs and collateral dredging to draw out pus by applying a plaster to the affected part reaches the drug rehabilitation purpose, many drawbacks of having avoided operation to bring when reaching identical drug abstinence;
2. Chinese medicine of the present invention is compared oral formulations and injection, and route of administration is short, and can not cause damage to patient's digestive system and blood circulation;
3. external Chinese medicine of the present invention is compared oral formulations and injection, and absorption process has been avoided the process of passing through blood brain barrier, and the drug effect performance is not given a discount;
4. because drug administration approach of the present invention is direct, concentrate to act on pinus, therefore can carry out the treatment of the treating the poisonous disease with poisonous drugs of high toxicity, high dose.
5. Chinese medicine of the present invention shows through animal model test (acute toxicity test, long term toxicity test and skin hypersensitivity experiment): it does not have any damage, side effect and anaphylaxis to each organ of human body and skin.In order to prove that further curative effect of the present invention provides clinical observation on the therapeutic effect report:
The present invention's external Chinese medicine (abbreviation drug-dropping) external application for curing opioid drug of quitting drug abuse relies on 4 routine clinical observation reports (People's Armed Police Zhejiang drug rehabilitation section of hospital of army unit)
The present invention's external external application of Chinese medicine treatment opioid drug of quitting drug abuse relies on, and adopts traditional Chinese medical science interior disease outer treating method, and the efficacy of a drug is by meridians in the scalp, cross meninges through the skull diploe, the through pinus in half brain and sphenoid sinus trigonum is eliminated patient's addiction maincenter fast from about the rear portion, reaches the withdrawal purpose.
My drug rehabilitation section of institute has successively carried out drug-dropping external application clinical treatment observation to 4 routine opioid drug dependents in JIUYUE, 2008, now will treat observed result and be reported as follows:
1. data and method
1.1 data in JIUYUE, 2008, among the volunteer addict that my drug rehabilitation section of institute accepts for medical treatment, have 4 people to agree to use the drug-dropping external application for curing, 4 routine patients are the male, all meet the diagnostic criteria that CCMD-3 heroin relies on, age 37-42 year, 39 ± 1.2 years old mean age, abuse time 2-8,6 ± 1.82 years average times, abuse dosage 0.5-1.0g/ day, mean dose 0.8 ± 1.2g/ day.Get rid of body complication, infectious disease and nervous system disease through health check-up and lab testing.
1.2 medicine: adopt the external Chinese medicine (abbreviation Chinese medicine paste for abstinence) of the embodiment of the invention 1 preparation to treat
1.3 conventional chest x-ray, electrocardiogram and blood routine examination before method patient's drug of topical application, and signing Informed Consent Form.Behind patient's head brain, shave the end outside the superior sagittal sinus portion and send out (5 centimeters scopes of about diameter), then the drug-dropping for preparing is spread on the outer position of hindbrain superior sagittal sinus cranium outward, with fixing the getting final product of surgical membrane stickup blended rubber cloth, determine dosage according to patient's opiates degree of dependence, general initial dose is between the 30-35 gram, later on each consumption is between the 20-30 gram, and more change dressings once every day, 5-7 days continuously.
1.4 withdrawal symptom and the evaluation of untoward reaction table (be the hospital stays observing time, removes 1 example and be in hospital 3 beyond the highest heavens, and other 3 example hospital stays is 12 days).20 observation index according to Beijing Medical University's drug dependence institute formulation, observe and record by the special messenger, every day 1 time, write down withdrawal symptom and untoward reaction in 24 hours, observation of symptoms comprises: crave for, anxiety, ferment, vomit, heating, fear of cold, yawn, shed tears, watery nasal discharge, perspiration, sleepy, Corium Gallus domesticus, tremble, arthralgia, feel sick, anorexia, diarrhoea, stomachache, insomnia, uncomfortable in chest, xerostomia.Untoward reaction comprises: dizziness, headache, drowsiness, malaise, blurred vision, and xerostomia, instability of gait, feel sick, vomiting, anorexia, stomachache, diarrhoea, constipation, erythra, sleep disorder, bone joint pain, easily enrage.
1.5 efficacy assessment standard is divided into produce effects, effective, invalid, is produce effects without cethadone treatment during treating, and be effectively with methadone on a small quantity, methadone dosage does not reduce and ends to treat is invalid.
2 results
1 routine patient invalid (during the treatment because of busy, treat stop for 3 times) is arranged among the result evaluation 4 routine patients, and all the other 3 routine patients are effectively (treatment time is 5 times) all.Effective percentage is 75%, and inefficiency is 25%.
2.1 have only 1 routine patient, 2 hours low grade fever of appearance in second day in treatment among the untoward reaction 4 routine patients, body temperature is at 37.6~C, unprocessed recovery voluntarily is normal.4 routine patients all occur drowsiness, and other untoward reaction does not all have.
3. know from experience
By 4 routine patient and clinical observations, the present invention's external Chinese medicine (Chinese medicine paste for abstinence) external application for curing opioid drug of quitting drug abuse relies on curative effect is preferably arranged, in therapeutic process, occur the short time low grade fever except that 1 example, all other untoward reaction is seen at the end, therefore think that the dependence of Chinese medicine paste for abstinence external application for curing opioid drug is safe, effective, have no side effect, untoward reaction is few, and has avoided the infringement of systems such as digestion that oral or quiet notes administration brings, circulation.
Because each patient's degree of dependence is indefinite, significant degree has certain difference, if this 4 routine patient's treatment number of times all reaches 7 times, curative effect may be better.
Because the case of observing is less, the time of observation is short, therefore can't rely on drug-dropping external application for curing opioid drug and draw comprehensive judgement, awaits further clinical observation.
" drug rehabilitation is pasted " clinical observation record
Observation unit: the doctor observes in People's Armed Police Zhejiang drug rehabilitation section of hospital of army unit:
-----------------
Remarks: asymptomatic (-) light symptoms (+) has main suit's (++) symptomatic treatment (+++) can't stand (++ ++)
" drug rehabilitation is pasted " clinical observation record
Observation unit: the doctor observes in People's Armed Police Zhejiang drug rehabilitation section of hospital of army unit:
-----------------
Remarks: asymptomatic (-) light symptoms (+) has main suit's (++) symptomatic treatment (+++) can't stand (++ ++)
" drug rehabilitation is pasted " clinical observation record
Observation unit: the doctor observes in People's Armed Police Zhejiang drug rehabilitation section of hospital of army unit:
-----------------
Remarks: asymptomatic (-) light symptoms () has main suit's (++) symptomatic treatment (+++) can't stand (++ ++)
" drug rehabilitation is pasted " clinical observation record
Observation unit: the doctor observes in People's Armed Police Zhejiang drug rehabilitation section of hospital of army unit:
-----------------
Remarks: asymptomatic (-) light symptoms (+) has main suit's (++) symptomatic treatment (+++) can't stand (++ ++)
The specific embodiment
Describe external Chinese medicine of the present invention in detail below in conjunction with embodiment, but the invention is not restricted to the following example.
Embodiment 1.
Get the raw materials ready:
Principal agent: Scorpio 10g, Radix Aconiti Kusnezoffii 20g, Radix Aconiti 25g, Gekko Swinhonis 30g, Semen Strychni 15g, Hirudo 60g, Galla Chinensis 60g, Radix Kansui 60g, sulfur 15g, Mylabris 8g, Borneolum Syntheticum (borneolum syntheticum) 4g, Camphora 3g, Catharsii molossi 25g, Moschus 5g, Bailey Myospalax Born 300g.
Excipient: Flos Daturae 15g, Radix Glycyrrhizae 10g, Flos Carthami 15g and 600g Shanxi mature vinegar.
Pharmacy:
(1) preparation principal agent: above-mentioned 15 kinds of principal agent crude drug are ground into fine powder with 800 order pulverizers respectively, and remix evenly back is standby;
(2) preparation excipient:
1) above-mentioned Flos Daturae, Radix Glycyrrhizae and Flos Carthami are ground into fine powder with 800 order pulverizers respectively;
2) fine powder that step 1) is prepared adds the Shanxi mature vinegar slow fire boiling of described 600g, until volume half;
(3) excipient of principal agent that step (1) is prepared and step (2) preparation promptly obtains external Chinese medicine of the present invention according to the weight ratio mix homogeneously of 4:6.
Embodiment 2.
Get the raw materials ready:
Principal agent: Scorpio 8g, Radix Aconiti Kusnezoffii 20g, Radix Aconiti 22g, Gekko Swinhonis 25g, Semen Strychni 18g, Hirudo 45g, Galla Chinensis 45g, Radix Kansui 60g, sulfur 12g, Mylabris 7g, Borneolum Syntheticum (borneolum syntheticum) 6g, Camphora 4g, Catharsii molossi 25g, Moschus 6g, Bailey Myospalax Born 400g.
Excipient: Flos Daturae 17g, Radix Glycyrrhizae 10g, Flos Carthami 17g and 500g Shanxi mature vinegar.
Pharmacy:
(1) preparation principal agent: above-mentioned 15 kinds of principal agent crude drug are ground into fine powder with 800 order pulverizers respectively, and remix evenly back is standby;
(2) preparation excipient:
1) above-mentioned Flos Daturae, Radix Glycyrrhizae and Flos Carthami are ground into fine powder with 800 order pulverizers respectively;
2) fine powder that step 1) is prepared adds the Shanxi mature vinegar slow fire boiling of described 500g, until volume half;
(3) excipient of principal agent that step (1) is prepared and step (2) preparation is mixed according to the weight ratio of 3:7, promptly obtains external Chinese medicine of the present invention.
Embodiment 3.
Get the raw materials ready:
Principal agent: Scorpio 15g, Radix Aconiti Kusnezoffii 35g, Radix Aconiti 45g, Gekko Swinhonis 40g, Semen Strychni 30g, Hirudo 70g, Galla Chinensis 80g, Radix Kansui 80g, sulfur 30g, Mylabris 25g, Borneolum Syntheticum (borneolum syntheticum) 8g, Camphora 5g, Catharsii molossi 85g, Moschus 28g, Bailey Myospalax Born 500g.
Excipient: Flos Daturae 18g, Radix Glycyrrhizae 12g, Flos Carthami 18g and 500g Shanxi mature vinegar.
Pharmacy:
(1) preparation principal agent: above-mentioned 15 kinds of principal agent crude drug are ground into fine powder with 800 order pulverizers respectively, and remix evenly back is standby;
(2) preparation excipient:
1) above-mentioned Flos Daturae, Radix Glycyrrhizae and Flos Carthami are ground into fine powder with 800 order pulverizers respectively;
2) fine powder that step 1) is prepared adds the Shanxi mature vinegar slow fire boiling of described 500g, until volume half;
(3) excipient of principal agent that step (1) is prepared and step (2) preparation is mixed according to the weight ratio of 4:6, promptly obtains external Chinese medicine of the present invention.

Claims (9)

1. a drug rehabilitation external Chinese medicine is made up of principal agent and auxiliary medicine, and it is characterized in that: the weight ratio of principal agent and auxiliary medicine is 3~4: 6~7, and described principal agent is prepared by the crude drug of following parts by weight:
Scorpio 1~15 Radix Aconiti Kusnezoffii 8~40 Radix Aconitis 20~50 Gekko Swinhonis 25~40
Semen Strychni 15~30 Hirudos 40~80 Galla Chinensiss 35~90 Radix Kansuis 35~90
Sulfur 8~30 Mylabris 3~25 Borneolum Syntheticums 2~8
Camphora 1~5 Catharsii molossi 10~90 Moschus 4~28 Bailey Myospalax Born 250~500;
Described auxiliary medicine is an excipient, and its raw material is: the Shanxi mature vinegar of Flos Daturae 15~20 weight portions, Radix Glycyrrhizae 8~12 weight portions, Flos Carthami 15~20 weight portions and 300~800 parts by weight.
2. a drug rehabilitation external Chinese medicine is made up of principal agent and auxiliary medicine, and it is characterized in that: the weight ratio of principal agent and auxiliary medicine is 3~4: 6~7, and described principal agent is prepared by the crude drug of following parts by weight:
Scorpio 7~9 Radix Aconiti Kusnezoffii 8~23 Radix Aconitis 20~25 Gekko Swinhonis 25~29
Semen Strychni 17~20 Hirudos 13~64 Galla Chinensiss 55~65 Radix Kansuis 55~65
Sulfur 7~14 Mylabris 6~7 Borneolum Syntheticums 4~6
Camphora 3~5 Catharsii molossis 22~27 Moschus 6~7 Bailey Myospalax Born
300~450;
Described auxiliary medicine is an excipient, and its raw material is: the Shanxi mature vinegar of Flos Daturae 15~20 weight portions, Radix Glycyrrhizae 8~12 weight portions, Flos Carthami 15~20 weight portions and 300~800 parts by weight.
3. claim 1 or 2 described arbitrary drug rehabilitation external Chinese medicines, it is characterized in that: the weight ratio that is mixed of principal agent and auxiliary medicine is 4: 6 or 3: 7.
4. the described drug rehabilitation external of claim 1 Chinese medicine is characterized in that described excipient material is: the Shanxi mature vinegar of Flos Daturae 17 weight portions, Radix Glycyrrhizae 10 weight portions, Flos Carthami 17 weight portions and 500 parts by weight.
5. the described drug rehabilitation external of claim 1 preparation method of Chinese medicine, its step is as follows:
(1) preparation principal agent: 15 kinds of crude drug pulverize separately of described ratio are become fine powder, and remix evenly back is standby;
(2) the preparation auxiliary medicine is an excipient:
1) Flos Daturae of 15~20 weight portions, the Radix Glycyrrhizae of 8~12 weight portions and the Flos Carthami pulverize separately of 15~20 weight portions are become fine powder;
2) fine powder that step 1) is prepared adds the Shanxi mature vinegar slow fire boiling of 300~800 weight portions, until volume half;
(3) excipient of principal agent that step (1) is prepared and step (2) preparation is according to 3~4: 6~7 weight ratio mix homogeneously promptly obtains described external Chinese medicine.
6. the described drug rehabilitation external of claim 5 preparation method of Chinese medicine, it is characterized in that: step (1) and (2) described pulverizing are with 800 order pulverizers described crude drug to be processed into fine powder.
7. the described drug rehabilitation external of claim 5 preparation method of Chinese medicine, it is characterized in that: the weight ratio that is mixed of described principal agent of step (3) and excipient is 4: 6.
8. the described drug rehabilitation external of claim 5 preparation method of Chinese medicine, it is characterized in that: the weight ratio that is mixed of described principal agent of step (3) and excipient is 3: 7.
9. the described drug rehabilitation external of claim 1 Chinese medicine is given up the application of human body to the medicine aspect the addiction of heroin, methamphetamine hydrochloride, Fructus Cannabis or head-shaking pill in preparation.
CN2008102271873A 2008-11-25 2008-11-25 External traditional Chinese medicine for giving up drug habits and preparation method Active CN101417021B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1640424A (en) * 2004-01-09 2005-07-20 胡馨元 Drug-dropping medicine and its preparing method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1640424A (en) * 2004-01-09 2005-07-20 胡馨元 Drug-dropping medicine and its preparing method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
丁寿根.戒毒品专利技术研究现状.《中国药物滥用防治杂志》.2000,(第6期),13-17页. *
郭希清等.虎骨及其替代品的研究进展.《陕西师范大学学报(自然科学版)》.2006,第34卷218-221页. *
靳怡然等.中药戒毒研究进展.《临床荟萃》.2008,第23卷(第4期),300-302页. *

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