CN101342267A - Donkey-hide gelatin angelica polymorpha & hoantchy particle and method of preparing the same - Google Patents
Donkey-hide gelatin angelica polymorpha & hoantchy particle and method of preparing the same Download PDFInfo
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- CN101342267A CN101342267A CNA2008100303884A CN200810030388A CN101342267A CN 101342267 A CN101342267 A CN 101342267A CN A2008100303884 A CNA2008100303884 A CN A2008100303884A CN 200810030388 A CN200810030388 A CN 200810030388A CN 101342267 A CN101342267 A CN 101342267A
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- corii asini
- colla corii
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- ethanol
- radix
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- 238000000034 method Methods 0.000 title claims abstract description 6
- 239000002245 particle Substances 0.000 title abstract 4
- 241001288870 Angelica polymorpha Species 0.000 title 1
- 108010010803 Gelatin Proteins 0.000 title 1
- 229920000159 gelatin Polymers 0.000 title 1
- 239000008273 gelatin Substances 0.000 title 1
- 235000019322 gelatine Nutrition 0.000 title 1
- 235000011852 gelatine desserts Nutrition 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 52
- 239000009636 Huang Qi Substances 0.000 claims abstract description 16
- 229930006000 Sucrose Natural products 0.000 claims abstract description 14
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 14
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims abstract description 10
- 235000013925 ferrous lactate Nutrition 0.000 claims abstract description 10
- 229940037907 ferrous lactate Drugs 0.000 claims abstract description 10
- 239000004225 ferrous lactate Substances 0.000 claims abstract description 10
- 238000004519 manufacturing process Methods 0.000 claims abstract description 10
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 claims abstract description 9
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000021286 stilbenes Nutrition 0.000 claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 230000008569 process Effects 0.000 claims abstract description 4
- 108010052008 colla corii asini Proteins 0.000 claims description 29
- 239000008187 granular material Substances 0.000 claims description 21
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000002244 precipitate Substances 0.000 claims description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 10
- 229930003268 Vitamin C Natural products 0.000 claims description 10
- 235000019154 vitamin C Nutrition 0.000 claims description 10
- 239000011718 vitamin C Substances 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 8
- 230000001476 alcoholic effect Effects 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
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- 241000238631 Hexapoda Species 0.000 claims description 3
- 241000607479 Yersinia pestis Species 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 239000012141 concentrate Substances 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000004821 distillation Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 239000002932 luster Substances 0.000 claims description 3
- 239000012567 medical material Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000012856 packing Methods 0.000 claims description 3
- 238000005453 pelletization Methods 0.000 claims description 3
- 238000002203 pretreatment Methods 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 239000006228 supernatant Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims 1
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- 235000013402 health food Nutrition 0.000 abstract description 3
- 206010067482 No adverse event Diseases 0.000 abstract description 2
- 241000125175 Angelica Species 0.000 abstract 3
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 3
- 239000003292 glue Substances 0.000 abstract 3
- 241001131629 Lancea Species 0.000 abstract 2
- 241000405414 Rehmannia Species 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
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- 239000011782 vitamin Substances 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 208000007502 anemia Diseases 0.000 description 5
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- 210000003743 erythrocyte Anatomy 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- MSTNYGQPCMXVAQ-KIYNQFGBSA-N 5,6,7,8-tetrahydrofolic acid Chemical compound N1C=2C(=O)NC(N)=NC=2NCC1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 MSTNYGQPCMXVAQ-KIYNQFGBSA-N 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- KSFOVUSSGSKXFI-GAQDCDSVSA-N CC1=C/2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(C=C)=C5C)C(C=C)=C4C)C(C)=C3CCC(O)=O)=C1CCC(O)=O Chemical compound CC1=C/2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(C=C)=C5C)C(C=C)=C4C)C(C)=C3CCC(O)=O)=C1CCC(O)=O KSFOVUSSGSKXFI-GAQDCDSVSA-N 0.000 description 1
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- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
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- 150000001413 amino acids Chemical class 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
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- 230000035619 diuresis Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 102000018146 globin Human genes 0.000 description 1
- 108060003196 globin Proteins 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 239000000413 hydrolysate Substances 0.000 description 1
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Abstract
The present invention relates to health food, ass-skin glue angelica stilbene particles which can improve the nutritional anemia, and a production method thereof. The active ingredients consist of raw materials which have the following weight ratio: 30 to 80 portions of ass-skin glue, 20 to 50 portion of angelica, 10 to 40 portions of prepared rhizome of rehmannia, 20 to 40 portions of radix astragali, 20 to 40 portions of Astraolylis lancea formalyrata, 1 to 4 portions of vitamin, 0.5 to 2 portions of ferrous lactate, and 750 to 1,000 portions of white sugar. The particles are molten by the ass-skin glue, extracted by the angelica, the prepared rhizome of rehmannia, the radix astragali and the Astraolylis lancea formalyrata, concentrated under the vacuum condition, deposited by alcohol which is then recycled, mixed, granulated, dried, cleaned, packaged, and processed with other technologies. The production method has the characteristics of scientific formula, reasonable process and so on. The trial on the human body has proven that the particles have the health function of improving the nutritional anemia, no adverse effects on health, but secure and reliable edible effects.
Description
Technical field:
The present invention relates to a kind of nutritional anemia of improvement health care foods that has.
Background technology:
According to World Health Organization's statistics, the whole world has 3,000,000,000 people to suffer from anemia in various degree approximately, and cause that because of suffering from anemia the dead number of all kinds of diseases is up to ten million every year.The population probability of middle national trouble anemia is higher than western countries, and in the crowd who suffers from anemia, the women is apparently higher than the male, and old man and child are higher than the young and the middle aged.In recent years, because of the nutritional disorder that factors such as the change of diet style, fat-reducing cause, formed the crowd of another class anemia.Therefore the health food market demand of improving nutritional anemia is huge.
It is many based on capsule, oral liquid formulation to have the nutritional anemia of improvement health care foods in the market, but its accumulating and take equal inconvenience, and prescription is complicated, the production cost height.
Summary of the invention:
The objective of the invention is to overcome the weak point of the existing health food of enriching blood, providing a kind of is primary raw material with Colla Corii Asini, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, the Radix Astragali and the Rhizoma Atractylodis Macrocephalae, adds an amount of trace elements iron and ascorbic Colla Corii Asini is returned stilbene granule and production method thereof.
Colla Corii Asini of the present invention is returned the stilbene granule, and its contained active component is made up of the following weight proportion raw material: Colla Corii Asini 30-80; Radix Angelicae Sinensis 20-50; Radix Rehmanniae Preparata 10-40; Radix Astragali 20-40; Rhizoma Atractylodis Macrocephalae 20-40; Vitamin C 1-4; Ferrous lactate 0.5-2; White sugar 750-1000.
Colla Corii Asini of the present invention is returned the particulate production method of stilbene, and its production process comprises:
A, Colla Corii Asini molten: the Colla Corii Asini of formula ratio is added in the jacketed pan, add the purified water of 1.8-2.2 times of weight, stir and be heated to Colla Corii Asini and all dissolve, boiling sterilization is 30 minutes again, puts cold standby;
B, medical material pre-treatment: with the nothing of formula ratio go mouldy, the Radix Angelicae Sinensis of free from insect pests, Radix Rehmanniae Preparata, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae respectively water clean up;
C, extraction: Radix Angelicae Sinensis, Radix Rehmanniae Preparata, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae that process B is obtained drop in the multi-function extractor, extracting in water 2 times, and add the water of 9-11 times of weight the first time, and after heated and boiled 1.8-2.5 hour, extracting solution filters with 120 order silks; Add for the second time the water of 7-9 times of weight, after heated and boiled 1.5-2 hour, extracting solution filters with 120 order silks; It is standby to merge secondary raffinate, and medicinal residues are abandoned it;
D, vacuum concentration: the extracting solution that operation C is obtained places vacuum concentrator to concentrate, and temperature is controlled at below 85 ℃, and vacuum is 0.04-0.06Mpa, and being concentrated into relative density is 1.08-1.10, gets concentrated solution, and cooling is stand-by;
E, precipitate with ethanol: the concentrated solution that step D is obtained carries out precipitate with ethanol, adds 95% edible ethanol and is 50%-55% to containing the alcohol amount, stirs, and leaves standstill 24 hours, get supernatant with 120 order silks filter alcoholic solution, stand-by;
F, reclaim ethanol: will above-mentioned alcoholic solution join and reclaim ethanol in the alcohol distillation column to there not being the alcohol flavor, the relative density of concentrated solution is 1.20-1.25, gets the precipitate with ethanol concentrated solution;
G, white sugar are pulverized: with the white sugar of formula ratio, pulverize with multifunctional crusher 80 eye mesh screens;
H, mixing: white sugar, the operation A that ferrous lactate, vitamin C, the operation G of formula ratio obtained obtains the precipitate with ethanol concentrated solution that Colla Corii Asini (melted) and operation F obtain and joins in the mixer, stirred 10-15 minute, and mix homogeneously, even to the mixture color and luster;
I, granulation: the mixed material that step H is obtained joins in the granulator, granulates with 14 eye mesh screens;
J, airpillow-dry: the granule that operation I is obtained joins in the boiling-bed drying, 70-80 ℃ airpillow-dry 25-35 minute, moisture Control is below 5%;
K, granulate: the dry good granule that operation J is obtained joins in the pelletizing machine, with 14 eye mesh screen granulate;
L, packing, warehouse-in.
In prescription of the present invention, the flavor of various raw materials, property, effect are:
Colla Corii Asini: sweet, flat.Return lung, liver, kidney channel.The effect tonifying blood and arresting bleeding is nourshing Yin and drynsessmoistening prescription.
Radix Angelicae Sinensis: sweet, hot, warm; Return liver, the heart, spleen channel; Effect is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Radix Rehmanniae Preparata: sweet, tepor; Return liver, kidney channel; The effect nourishing YIN and supplementing blood, beneficial essence is filled out marrow.
The Radix Astragali: sweet, tepor; Return lung, spleen channel; Effect invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, return spleen, stomach warp.The effect invigorating the spleen and benefiting QI, the dampness diuretic.
Vitamin C: effect promotes the absorption of ferrum.
Ferrous lactate: effect is replenished ferrum.
Colla Corii Asini is many to be made up of ossein and partial hydrolysate thereof, contains total nitrogen and is about 16%, is mainly protein.The aminoacid that hydrolysis generates has lysine, arginine, histidine etc., has good blood tonification effect; Colla Corii Asini and Radix Angelicae Sinensis, the Radix Astragali, Radix Rehmanniae Preparata share, the effect of then enriching blood better (selecting from " science of prescription ").Ferrum is the synthetic requisite material of haemachrome of erythrocyte, absorb intravital ferrum and combine the formation haemachrome with protoporphyrin, haemachrome combines with globin and forms hemoglobin, and then the sophisticated erythrocyte of bud into, and vitamin C can promote folic acid to become tetrahydrofolic acid, and it is synthetic to help nucleic acid, promotes the erythrocyte growth, can make Fe3+ be reduced into Fe2+, thereby easily be absorbed by the body.
In sum, more than all medicines be monarch with the Colla Corii Asini nourishing blood, Radix Angelicae Sinensis is invigorated blood circulation and is minister, is aided with the Radix Rehmanniae Preparata YIN nourishing, the Radix Astragali, Rhizoma Atractylodis Macrocephalae QI invigorating, ferrous lactate iron supplement, vitamin C promote absorbing of ferrum, thereby reach the purpose of improving nutritional anemia.Have characteristics such as scientific formulation, technology be reasonable.Through human feeding trial, have the health care that improves nutritional anemia, and health is had no adverse effects, edible safety, reliable.
The specific embodiment:
Colla Corii Asini is returned the stilbene granule, is made up of the following weight proportion raw material: Colla Corii Asini 70; Radix Angelicae Sinensis 40; Radix Rehmanniae Preparata 30; The Radix Astragali 30; The Rhizoma Atractylodis Macrocephalae 30; Vitamin C 3; Ferrous lactate 1.1; White sugar 900.
Its production process comprises:
A, Colla Corii Asini molten: the Colla Corii Asini of formula ratio is added in the jacketed pan, add the purified water of 2 times of weight, stir and be heated to Colla Corii Asini and all dissolve, boiling sterilization is 30 minutes again, puts cold standby;
B, medical material pre-treatment: with the nothing of formula ratio go mouldy, the Radix Angelicae Sinensis of free from insect pests, Radix Rehmanniae Preparata, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae respectively water clean up;
C, extraction: Radix Angelicae Sinensis, Radix Rehmanniae Preparata, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae that process B is obtained drop in the multi-function extractor, extracting in water 2 times, and add the water of 10 times of weight the first time, and heated and boiled is after 2 hours, and extracting solution filters with 120 order silks; Add for the second time the water of 8 times of weight, heated and boiled is after 1.5 hours, and extracting solution filters with 120 order silks; It is standby to merge secondary raffinate, and medicinal residues are abandoned it;
D, vacuum concentration: the extracting solution that operation C is obtained places vacuum concentrator to concentrate, and temperature is controlled at below 85 ℃, and vacuum is 0.04-0.06Mpa, and being concentrated into relative density is 1.08-1.10 (75 ℃ of heat are surveyed), gets concentrated solution, and cooling is stand-by;
E, precipitate with ethanol: the concentrated solution that step D is obtained carries out precipitate with ethanol, adds 95% edible ethanol and is 50%-55% to containing the alcohol amount, stirs, and leaves standstill 24 hours, get supernatant with 120 order silks filter alcoholic solution, stand-by;
F, reclaim ethanol: will above-mentioned alcoholic solution join and reclaim ethanol in the alcohol distillation column to there not being the alcohol flavor, the relative density of concentrated solution is 1.20-1.25 (75 ℃ of heat is surveyed), gets the precipitate with ethanol concentrated solution;
G, white sugar are pulverized: with the white sugar of formula ratio, pulverize with multifunctional crusher 80 eye mesh screens;
H, mixing: white sugar, the operation A that ferrous lactate, vitamin C, the operation G of formula ratio obtained obtains the precipitate with ethanol concentrated solution that Colla Corii Asini (melted) and operation F obtain and joins in the mixer, stirred 10-15 minute, and mix homogeneously, even to the mixture color and luster;
I, granulation: the mixed material that step H is obtained joins in the granulator, granulates with 14 eye mesh screens;
J, airpillow-dry: the granule that operation I is obtained joins in the boiling-bed drying, 70-80 ℃ airpillow-dry 25-35 minute, moisture Control is below 5%;
K, granulate: the dry good granule that operation J is obtained joins in the pelletizing machine, with 14 eye mesh screen granulate;
L, packing, warehouse-in.
Claims (3)
1, a kind of Colla Corii Asini is returned the stilbene granule, it is characterized in that: its contained active component is made up of the following weight proportion raw material: Colla Corii Asini 30-80; Radix Angelicae Sinensis 20-50; Radix Rehmanniae Preparata 10-40; Radix Astragali 20-40; Rhizoma Atractylodis Macrocephalae 20-40; Vitamin C 1-4; Ferrous lactate 0.5-2; White sugar 750-1000.
2, Colla Corii Asini according to claim 1 is returned the stilbene granule, it is characterized in that: its contained active component is made up of the following weight proportion raw material: Colla Corii Asini 70; Radix Angelicae Sinensis 40; Radix Rehmanniae Preparata 30; The Radix Astragali 30; The Rhizoma Atractylodis Macrocephalae 30; Vitamin C 3; Ferrous lactate 1.1; White sugar 900.
3, a kind of production claim 1 or 2 described Colla Corii Asini are returned the particulate method of stilbene, and its production process comprises:
A, Colla Corii Asini molten: the Colla Corii Asini of formula ratio is added in the jacketed pan, add the purified water of 1.8-2.2 times of weight, stir and be heated to Colla Corii Asini and all dissolve, boiling sterilization is 30 minutes again, puts cold standby;
B, medical material pre-treatment: with the nothing of formula ratio go mouldy, the Radix Angelicae Sinensis of free from insect pests, Radix Rehmanniae Preparata, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae respectively water clean up;
C, extraction: Radix Angelicae Sinensis, Radix Rehmanniae Preparata, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae that process B is obtained drop in the multi-function extractor, extracting in water 2 times, and add the water of 9-11 times of weight the first time, and after heated and boiled 1.8-2.5 hour, extracting solution filters with 120 order silks; Add for the second time the water of 7-9 times of weight, after heated and boiled 1.5-2 hour, extracting solution filters with 120 order silks; It is standby to merge secondary raffinate, and medicinal residues are abandoned it;
D, vacuum concentration: the extracting solution that operation C is obtained places vacuum concentrator to concentrate, and temperature is controlled at below 85 ℃, and vacuum is 0.04-0.06Mpa, and being concentrated into relative density is 1.08-1.10, gets concentrated solution, and cooling is stand-by;
E, precipitate with ethanol: the concentrated solution that step D is obtained carries out precipitate with ethanol, adds 95% edible ethanol and is 50%-55% to containing the alcohol amount, stirs, and leaves standstill 24 hours, get supernatant with 120 order silks filter alcoholic solution, stand-by;
F, reclaim ethanol: will above-mentioned alcoholic solution join and reclaim ethanol in the alcohol distillation column to there not being the alcohol flavor, the relative density of concentrated solution is 1.20-1.25, gets the precipitate with ethanol concentrated solution;
G, white sugar are pulverized: with the white sugar of formula ratio, pulverize with multifunctional crusher 80 eye mesh screens;
H, mixing: white sugar, the operation A that ferrous lactate, vitamin C, the operation G of formula ratio obtained obtains the precipitate with ethanol concentrated solution that Colla Corii Asini (melted) and operation F obtain and joins in the mixer, stirred 10-15 minute, and mix homogeneously, even to the mixture color and luster;
I, granulation: the mixture liquid that step H is obtained joins in the granulator, granulates with 14 eye mesh screens;
J, airpillow-dry: the granule that operation I is obtained joins in the boiling-bed drying, 70-80 ℃ airpillow-dry 25-35 minute, moisture Control is below 5%;
K, granulate: the dry good granule that operation J is obtained joins in the pelletizing machine, with 14 eye mesh screen granulate;
L, packing, warehouse-in.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810030388A CN101342267B (en) | 2008-08-20 | 2008-08-20 | Donkey-hide gelatin angelica polymorpha & hoantchy particle and method of preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810030388A CN101342267B (en) | 2008-08-20 | 2008-08-20 | Donkey-hide gelatin angelica polymorpha & hoantchy particle and method of preparing the same |
Publications (2)
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579598A (en) * | 2011-01-06 | 2012-07-18 | 北京宝德润生医药科技发展有限公司 | Composition used for improving nutritional anaemia and preparation method thereof |
| CN102631470A (en) * | 2012-05-05 | 2012-08-15 | 钱家美 | Ejiao Guiqi granules and manufacturing method thereof |
| CN105105148A (en) * | 2015-09-23 | 2015-12-02 | 威海紫光金奥力生物技术有限公司 | Method for producing gelatina nigra preparation for improving nutritional anemia |
| CN105250996A (en) * | 2015-10-30 | 2016-01-20 | 上海善力健生物科技有限公司 | Biological agent for treating iron-deficiency anemia, preparation method thereof and purpose thereof |
| CN115219628A (en) * | 2022-07-19 | 2022-10-21 | 东阿阿胶股份有限公司 | Pretreatment method of compound donkey-hide gelatin slurry and detection method of oligosaccharide in compound donkey-hide gelatin slurry |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1456229A (en) * | 2003-02-12 | 2003-11-19 | 毛友昌 | Preparation of donkey hide gelatin effervescent granules for nourishing blood |
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2008
- 2008-08-20 CN CN200810030388A patent/CN101342267B/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579598A (en) * | 2011-01-06 | 2012-07-18 | 北京宝德润生医药科技发展有限公司 | Composition used for improving nutritional anaemia and preparation method thereof |
| CN102631470A (en) * | 2012-05-05 | 2012-08-15 | 钱家美 | Ejiao Guiqi granules and manufacturing method thereof |
| CN105105148A (en) * | 2015-09-23 | 2015-12-02 | 威海紫光金奥力生物技术有限公司 | Method for producing gelatina nigra preparation for improving nutritional anemia |
| CN105250996A (en) * | 2015-10-30 | 2016-01-20 | 上海善力健生物科技有限公司 | Biological agent for treating iron-deficiency anemia, preparation method thereof and purpose thereof |
| CN115219628A (en) * | 2022-07-19 | 2022-10-21 | 东阿阿胶股份有限公司 | Pretreatment method of compound donkey-hide gelatin slurry and detection method of oligosaccharide in compound donkey-hide gelatin slurry |
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| CN101342267B (en) | 2010-05-12 |
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