CN101314015A

CN101314015A - Medicament for treating children's asthma

Info

Publication number: CN101314015A
Application number: CNA2008101407113A
Authority: CN
Inventors: 王俊芳
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-07-21
Filing date: 2008-07-21
Publication date: 2008-12-03
Anticipated expiration: 2028-07-21
Also published as: CN101314015B

Abstract

The invention relates to a medicine for treating infantile asthma. The invention relates to a medicine, which is prepared by the following raw materials by weight portion: 4 to 10 portions of ephedra herb, 4 to 10 portions of tatarian aster root, 4 to 10 portions of common coltsfoot flower, 4 to 10 portions of stemona roots, 4 to 10 portions of pepperweed seeds, 4 to 10 portions of Fritillaria cirrhosa, 4 to 10 portions of perillaseed, 4 to 10 portions of dried tangerine or orange peels, 2 to 5 portions of rhizoma pinelliae preparata, 2 to 5 portions of radix glycyrrhizae preparata, 2 to 5 portions of almond and 2 to 5 portions of earthworms. When the medicine is manufactured, 160 to 240 portions of water are added into the raw materials for decoction of 30 minutes under the condition of low fire, and the medicine is obtained after cooking and taking cooking liquor. The medicine has the advantages that: 'Huanglong Dingchuan Tang' manufactured by adoption of the method is convenient to take and has definite healing effect, and the cure rate reaches 90.6 percent; no obvious side effect exists, and the cost is low; and the 'Huanglong Dingchuan Tang' deserves clinic promotion extraordinarily.

Description

The medicine of treatment children's asthma

Technical field:

The present invention relates to medicine, especially for the medicine of treatment infant respiratory infection diseases.

Background technology:

The sample bronchitis of panting is a kind of common infant respiratory tract infection, be more common in the 1-3 children's in year, its cause of disease is that trachea, the bronchus owing to the baby is narrower and small on dissecting, elastic fibers is grown imperfection around it, easily due to illness poison infection or the stimulation of other pathology make mucosa swelling hyperemia, cause that tracheal stenosis and resistance increase.To stridulate, some cases has recurrent clinically, most prognosis bona, generally after 3-4 year along with body's immunity strengthens, recurrent number reduces and fully recovers.But though, often can not obtain satisfactory effect in a short time clinically through infection and symptomatic treatment mitigation symptoms.

Summary of the invention:

Purpose of the present invention just provides a kind of medicine that is used for the treatment of children's asthma, its taking convenience, and curative effect is sure, non-evident effect, expense is low.

The objective of the invention is to realize by following scheme: the medicine of treatment children's asthma is characterized in that it being that raw material by following weight portion is made: 4～10 parts of Herba Ephedrae (processed), 4～10 parts of honey-fried RADIX ASTERISs, 4～10 parts of honey-fried FLOS FARFARAEs, 4～10 parts of the Radixs Stemonae, 4～10 parts of Semen Lepidii (Semen Descurainiae)s, 4～10 parts of Bulbus Fritillariae Cirrhosaes, 4～10 parts of Fructus Perillaes, 4～10 parts of Pericarpium Citri Reticulataes, 2～5 parts of Rhizoma Pinelliae, 2～5 parts of Radix Glycyrrhizae Preparatas, 2～5 parts in Semen Armeniacae Amarum, 2～5 parts of Pheretimas.

Preferable range is: 6～8 parts of Herba Ephedrae (processed), 6～8 parts of honey-fried RADIX ASTERISs, 6～8 parts of honey-fried FLOS FARFARAEs, 6～8 parts of the Radixs Stemonae, Semen Lepidii give 6～8 parts, 6～8 parts of Bulbus Fritillariae Cirrhosaes, 6～8 parts of Fructus Perillaes, 6～8 parts of Pericarpium Citri Reticulataes, 3～4 parts of Rhizoma Pinelliae, 3～4 parts of Radix Glycyrrhizae Preparatas, 3～4 parts in Semen Armeniacae Amarum, 3～4 parts of Pheretimas.

Preferred plan is: 7 parts of Herba Ephedrae (processed), 7 parts of honey-fried RADIX ASTERISs, 7 parts of honey-fried FLOS FARFARAEs, 7 parts of the Radixs Stemonae, 7 parts of Semen Lepidii (Semen Descurainiae)s, 7 parts of Bulbus Fritillariae Cirrhosaes, 7 parts of Fructus Perillaes, 7 parts of Pericarpium Citri Reticulataes, 3.5 parts of Rhizoma Pinelliae, 3.5 parts of Radix Glycyrrhizae Preparatas, 3.5 parts in Semen Armeniacae Amarum, 3.5 parts of Pheretimas.

During making, add 160～240 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction.

Testing data:

1, physical data: 172 examples that will accept for medical treatment the sample bronchitis infant of panting is divided into two groups at random, " HUANGLONG DINGCHUAN TANG " the treatment group (observation group) that adopts the inventive method to make is used intravenous drips (matched group) such as shuanghuanglian powder injection, aminophylline pin, dexamethasone pin, phentolamine pin with the general treatment group, two groups of cases all meet " practical paidonosology " the sample bronchitis diagnostic criteria of panting, and comparability is arranged.In observation group's 86 examples, male 70 examples, women 16 examples, average 1.6 years old of age; In matched group 86 examples, male 66 examples, women 20 examples, average 1.4 years old of age, 1-3 days 63 examples of being admitted to hospital of falling ill, 23 examples of being admitted to hospital more than 4 days of falling ill.Clinical setting sees Table 1.

Table 1 clinical manifestation unit: example

Symptom and sign	Observation group	Matched group
Symptom and sign	Observation group	Matched group	Asthma	86	86
Cough	31	35	Asthma	86	86
Cough	31	35	Heating	23	23
Rale	86	86	Heating	23	23

2, Therapeutic Method

10 milliliters of each decoction being taken warmly, every day three times, logotype 2-3 days, the other medicines of stopping using during the treatment.

3, treatment standard

Cure: asthma, cough are alleviated, and body temperature is normal, and rale disappears;

Take a turn for the better: asthma, cough alleviate, and body temperature is normal, and rale reduces;

Invalid: symptom, sign no change or increase the weight of.

Medication three days was the efficacy determination time.

4, therapeutic effect

See table 2 for details.

Table 2: therapeutic outcome unit: example

Group	Cure (cure rate)	Take a turn for the better (improvement rate)	Invalid (inefficiency)
Group	Cure (cure rate)	Take a turn for the better (improvement rate)	Invalid (inefficiency)	Observation group	78(90.6％)	8(9.3％)	0(0％)
Matched group	12(13.9％)	39(45.3％)	35(40.6％)	Observation group	78(90.6％)	8(9.3％)	0(0％)

Table 2 result shows: observation group's cure rate 90.6%, matched group cure rate 13.9% is learned by statistics and is handled X ²There is highly significant difference=43.94 P＜0.005, curative effect.

Concrete case:

1, journey so-and-so, the man 2 years old, is chief complaint and goes to a doctor with " cough, asthma 5 days ".Persistence dry cough appears in infant no obvious inducement before 5 days, companion's asthma, and body temperature is normal.Once in medicines such as local commune hospital's intravenous drip penicillin, shuanghuanglian powder injection, aminophylline, weak effect.Diet is general, and two is just normal, and spirit can.Have a medical check-up: T:37.1 ℃, R:55 time/minute, the two lung audibles and the sound of stridulating.19 of blood show: leukocyte and type thereof are normal substantially, and rabat shows: two increased bronchovascular shadows.Give the HUANGLONG relieve asthma oral liquid, take cough after three days, asthma symptom disappearance, auscultation two pulmonary respiration sounds are coarse.It is clear to take after five days auscultation two pulmonary respiration sounds.

2, Lee so-and-so, the woman 1.5 years old, is chief complaint and goes to a doctor with " cough, 1 week of asthma, the heat that occurs together one day ".Companion's asthma, low grade fever frequent cough appears, in infant no obvious inducement before 7 days.Once in the oral azithromycin of local clinic, QINGRE JIEDU KOUFUYE medicine, weak effect.Diet is general, and two is just normal, and spirit can.Have a medical check-up: T:37.6 ℃, R:60 time/minute, two lung audibles and stridulate sound and rale sound.19 of blood show: leukocyte and type thereof are normal substantially, and rabat shows: two increased bronchovascular shadows.Give the HUANGLONG relieve asthma oral liquid, take cough after two days, asthma symptom disappearance, body temperature is normal, and auscultation two pulmonary respiration sounds are clear.

Among the present invention: Herba Ephedrae, Pheretima have remarkable dilating effect to bronchus; Bulbus Fritillariae Cirrhosae still can reduce the bronchus secretion except that expansible bronchial smooth muscle; Radix Glycyrrhizae has effects such as anti-inflammatory, eliminating phlegm and stopping cough; That Radix Asteris, Flos Farfarae, the Radix Stemonae have is antibiotic, antiviral and relieving asthma, effect such as cough-relieving; Semen Lepidii (Semen Descurainiae), Fructus Perillae, Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Semen Armeniacae Amarum have cough-relieving or effect such as relieving asthma, eliminate the phlegm.But the detailed mechanism of action of Chinese medicine awaits further discussion.

The present invention has significant effect: its taking convenience, and curative effect is sure, and cure rate reaches 90.6%; Non-evident effect, expense is low.Be worth very much clinical expansion.

The specific embodiment:

Below in conjunction with embodiment the present invention is done further narration:

Embodiment 1: select: 4.5 parts of Herba Ephedrae (processed), 4.5 parts of honey-fried RADIX ASTERISs, 4.5 parts of Flos Farfarae (processed)s, 4.5 parts of the Radixs Stemonae, 4.5 parts of Semen Lepidii (Semen Descurainiae)s, 4.5 parts of Bulbus Fritillariae Cirrhosaes, 4.5 parts of Fructus Perillae, 4.5 parts of Pericarpium Citri Reticulataes (Pericarpium Citri tangerinae), 2.5 parts of Rhizoma Pinelliae, 2.5 parts of Radix Glycyrrhizae Preparatas, 2.5 parts in Semen Armeniacae Amarum, 2.5 parts of Pheretimas (Lumbricus); During making, add 170 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction, generally boiled and got 20-30 milliliter decoction.

Embodiment 2: select: 9.5 parts of Herba Ephedrae (processed), 9.5 parts of honey-fried RADIX ASTERISs, 9.5 parts of honey-fried FLOS FARFARAEs, 9.5 parts of the Radixs Stemonae, 9.5 parts of Semen Lepidii (Semen Descurainiae)s, 9.5 parts of Bulbus Fritillariae Cirrhosaes, 9.5 parts of Fructus Perillaes, 9.5 parts of Pericarpium Citri Reticulataes, 4.5 parts of Rhizoma Pinelliae, 4.5 parts of Radix Glycyrrhizae Preparatas, 4.5 parts in Semen Armeniacae Amarum, 4.5 parts of Pheretimas.During making, add 230 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction.

Embodiment 3: select: 6.5 parts of Herba Ephedrae (processed), 6.5 parts of honey-fried RADIX ASTERISs, 6.5 parts of honey-fried FLOS FARFARAEs, 6.5 parts of the Radixs Stemonae, 6.5 parts of Semen Lepidii (Semen Descurainiae)s, 6.5 parts of Bulbus Fritillariae Cirrhosaes, 6.5 parts of Fructus Perillaes, 6.5 parts of Pericarpium Citri Reticulataes, 3.2 parts of Rhizoma Pinelliae, 3.2 parts of Radix Glycyrrhizae Preparatas, 3.2 parts in Semen Armeniacae Amarum, 3.2 parts of Pheretimas.During making, add 180 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction.

Embodiment 4: select: 7.5 parts of Herba Ephedrae (processed), 7.5 parts of honey-fried RADIX ASTERISs, 7.5 parts of honey-fried FLOS FARFARAEs, 7.5 parts of the Radixs Stemonae, 7.5 parts of Semen Lepidii (Semen Descurainiae)s, 7.5 parts of Bulbus Fritillariae Cirrhosaes, 7.5 parts of Fructus Perillaes, 7.5 parts of Pericarpium Citri Reticulataes, 3.8 parts of Rhizoma Pinelliae, 3.8 parts of Radix Glycyrrhizae Preparatas, 3.8 parts in Semen Armeniacae Amarum, 3.8 parts of Pheretimas.During making, add 220 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction.

Embodiment 5: select: 7 parts of Herba Ephedrae (processed), 7 parts of honey-fried RADIX ASTERISs, 7 parts of honey-fried FLOS FARFARAEs, 7 parts of the Radixs Stemonae, 7 parts of Semen Lepidii (Semen Descurainiae)s, 7 parts of Bulbus Fritillariae Cirrhosaes, 7 parts of Fructus Perillaes, 7 parts of Pericarpium Citri Reticulataes, 3.5 parts of Rhizoma Pinelliae, 3.5 parts of Radix Glycyrrhizae Preparatas, 3.5 parts in Semen Armeniacae Amarum, 3.5 parts of Pheretimas.During making, add 200 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction.

Claims

1, the medicine of treatment children's asthma is characterized in that it being that raw material by following weight portion is made: 4～10 parts of Herba Ephedrae (processed), 4～10 parts of honey-fried RADIX ASTERISs, 4～10 parts of honey-fried FLOS FARFARAEs, 4～10 parts of the Radixs Stemonae, 4～10 parts of Semen Lepidii (Semen Descurainiae)s, 4～10 parts of Bulbus Fritillariae Cirrhosaes, 4～10 parts of Fructus Perillaes, 4～10 parts of Pericarpium Citri Reticulataes, 2～5 parts of Rhizoma Pinelliae, 2～5 parts of Radix Glycyrrhizae Preparatas, 2～5 parts in Semen Armeniacae Amarum, 2～5 parts of Pheretimas.

2, the medicine of treatment children's asthma according to claim 1 is characterized in that the component of each crude drug is: 6～8 parts of Herba Ephedrae (processed), 6～8 parts of honey-fried RADIX ASTERISs, 6～8 parts of honey-fried FLOS FARFARAEs, 6～8 parts of the Radixs Stemonae, 6～8 parts of Semen Lepidii (Semen Descurainiae)s, 6～8 parts of Bulbus Fritillariae Cirrhosaes, 6～8 parts of Fructus Perillaes, 6～8 parts of Pericarpium Citri Reticulataes, 3～4 parts of Rhizoma Pinelliae, 3～4 parts of Radix Glycyrrhizae Preparatas, 3～4 parts in Semen Armeniacae Amarum, 3～4 parts of Pheretimas.

3, the medicine of treatment children's asthma according to claim 1 is characterized in that the component of each crude drug is: 7 parts of Herba Ephedrae (processed), 7 parts of honey-fried RADIX ASTERISs, 7 parts of honey-fried FLOS FARFARAEs, 7 parts of the Radixs Stemonae, 7 parts of Semen Lepidii (Semen Descurainiae)s, 7 parts of Bulbus Fritillariae Cirrhosaes, 7 parts of Fructus Perillaes, 7 parts of Pericarpium Citri Reticulataes, 3.5 parts of Rhizoma Pinelliae, 3.5 parts of Radix Glycyrrhizae Preparatas, 3.5 parts in Semen Armeniacae Amarum, 3.5 parts of Pheretimas.

4, according to claim 1 or 2 or the manufacture method of the medicine of 3 or 4 described treatment children's asthmas, it is characterized in that: during making, add 160～240 parts in water, low baking temperature was fried in shallow oil 30 minutes, boiled and got decoction.