CN101248064B - Nitrocatechol derivatives as COMT inhibitors - Google Patents

Nitrocatechol derivatives as COMT inhibitors Download PDF

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Publication number
CN101248064B
CN101248064B CN2006800266140A CN200680026614A CN101248064B CN 101248064 B CN101248064 B CN 101248064B CN 2006800266140 A CN2006800266140 A CN 2006800266140A CN 200680026614 A CN200680026614 A CN 200680026614A CN 101248064 B CN101248064 B CN 101248064B
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CN
China
Prior art keywords
base
nitrophenyl
oxadiazole
oxygen
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN2006800266140A
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Chinese (zh)
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CN101248064A (en
Inventor
D·A·利尔蒙斯
L·E·基什
P·N·莱亚尔·帕尔马
H·多斯·桑托斯·费雷拉
P·M·V·阿劳若·苏亚雷斯·达·西尔瓦
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Bial Portela and Cia SA
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Bial Portela and Cia SA
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Priority to GB0515327.5 priority Critical
Priority to GB0515327A priority patent/GB0515327D0/en
Priority to EP06008203 priority
Priority to EP06008203.9 priority
Priority to EP06011073 priority
Priority to EP06011073.1 priority
Application filed by Bial Portela and Cia SA filed Critical Bial Portela and Cia SA
Priority to PCT/PT2006/000020 priority patent/WO2007013830A1/en
Priority claimed from CN201210142381.8A external-priority patent/CN102816157B/en
Publication of CN101248064A publication Critical patent/CN101248064A/en
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Publication of CN101248064B publication Critical patent/CN101248064B/en
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