CN101124943B - Feed additive capable of increasing animal and bird intestines physiological function - Google Patents

Feed additive capable of increasing animal and bird intestines physiological function Download PDF

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Publication number
CN101124943B
CN101124943B CN2007100532056A CN200710053205A CN101124943B CN 101124943 B CN101124943 B CN 101124943B CN 2007100532056 A CN2007100532056 A CN 2007100532056A CN 200710053205 A CN200710053205 A CN 200710053205A CN 101124943 B CN101124943 B CN 101124943B
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China
Prior art keywords
animal
feed additive
feed
physiological function
feed addictive
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CN2007100532056A
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Chinese (zh)
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CN101124943A (en
Inventor
侯永清
丁斌鹰
刘玉兰
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武汉工业学院
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Publication of CN101124943A publication Critical patent/CN101124943A/en
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Publication of CN101124943B publication Critical patent/CN101124943B/en

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Abstract

The present invention discloses a feed additive which is used for increasing the enteric canal physiological function of animal and poultry. The feed additive is made by preparing the two matters of arginine and Alpha -ketoglutaric acid in certain proportion. The present invention has the outstanding advantages that the feed additive can effectively promote the development of the bowel mucosal and maintain a barrier of the bowel mucosal, thereby reinforcing the enteric canal immunologic function and the alimentation absorbing effect. The feed additive can also promote the growth of the animal and poultry, and increase the feed transformation efficiency and reduce the incidence rate of the enteric canal diseases.

Description

A kind of feed addictive of promoting the animal and bird intestines physiological function
Technical field
The invention belongs to herding or field of feed, relate to feed addictive, be specifically related to a kind of feed addictive of promoting the animal and bird intestines physiological function.
Background technology
Enteron aisle is not only the organ of digesting and assimilating of the interior maximum of livestock and poultry body, is the final absorption places of all nutriments, also is simultaneously immune organ maximum in the body.The development condition of enteron aisle and immunization barrier function thereof are most important with health to the growth of livestock and poultry.Children domestic animal in age, as newborn piglet, enteron aisle is among the quick growth, structure and function imperfection, digest and assimilate and the immunization barrier function of nutrient have significant limitation.In addition, ablactation stress causes intestinal mucosa atrophy, gut epithelium integrality and gut barrier is destroyed and function of intestinal canal is disorderly.In the prior art, do not see the feed addictive of intestinal growth situation, maintenance and the enhancement intestinal immunological barrier function that can effectively improve piglet.
Summary of the invention
The purpose of this invention is to provide a kind of feed addictive of promoting the animal and bird intestines physiological function.
In feed, add and to promote the additive of animal and bird intestines physiological function, can improve the growth of animals or poultry performance and the general level of the health, reduce the use of growth accelerator and medicine, for the healthy sustainable development of aquaculture lays the foundation.
Can promote the mucosal epithelium Growth and Differentiation based on arginine, the mucous membrane structure is obviously improved, safeguard gut barrier; KG can be used as a kind of selectivity metabolism fuel of enterocyte, keeps the integrality of gastrointestinal epithelial, strengthens the intestine immunity function.Arginine is synthetic precursor substance of polyamines and the synthetic unique substrate of nitric oxide, and KG is the precursor substance of glutamine, both regulate the intestinal physiology function by different mechanisms, and its composition can be promoted the animal and bird intestines physiological function more effectively than one matter.
The technical measures that the present invention adopts are as follows:
A kind of feed addictive of promoting the animal and bird intestines physiological function is characterized in that: this feed addictive is that usefulness arginine, two kinds of materials of KG are formulated in proportion, and the mass ratio of arginine and KG is: 0.5~2: 1.
The using method of promoting the feed addictive of animal and bird intestines physiological function is: addition is 0.05%~1.0% according to feed gross weight meter, directly this product is added in the animal and fowl fodder; Or this product and carrier be mixed and made into pre-mixing agent; Or be mixed and made into premix, the concentrate feed form livestock and poultry of feeding with other feed addictive or feedstuff.
Advantage of the present invention is: the feed addictive of promoting the animal and bird intestines physiological function can improve the intestinal mucosa structure, strengthens intestinal absorption ability, and then promotes to improve food utilization efficiency by growth of animals or poultry, reduces the use of growth accelerator; This feed addictive is safeguarded gut barrier, is strengthened the intestine immunity function, and then improves the health status of animal and bird intestines and body, reduces the use of medicine; Compare with the antibiotics growth-promoting additive have have no side effect, drug residue free, pollution-free, the advantage that is of value to animal and human's class health.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further described.
Embodiment 1
Arginine, two kinds of materials of KG are pressed mass ratio combination in 1: 1, compound is mixed, obtain a kind of feed addictive of promoting the animal and bird intestines physiological function.
Carry out the weanling pig test with this additive.48 weanling pigs are divided into two groups, three repetitions of every component (hurdle), 8 on every hurdle.Piglet source, age in days, body weight are approaching, the sex unanimity.Two groups of basal diet unanimities, test group is added 0.5% feed addictive of the present invention, and the blank group does not add feed addictive of the present invention.The results are shown in Table 1, table 2 and table 3.
Table 1 adds the influence (unit: mmol/L) of the additive of enhancement intestinal physiology function to weanling pig serum D-xylose concentration
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
Table 2 adds the influence of the additive of enhancement intestinal physiology function to weanling pig intestinal villi height/crypts degree of depth
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
Table 3 adds the influence of the additive of enhancement intestinal physiology function to the weanling pig growth performance
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
The result shows, uses feed addictive of the present invention, compares with the blank group, can significantly improve piglet small intestinal mucosa structure, promote intestinal absorption ability; The piglet daily gain improves 23.9%; The material anharmonic ratio reduces by 11.2%; Diarrhea rate reduces by 51.6%.
Embodiment 2
Arginine, two kinds of materials of KG are made up in 2: 1 ratios, compound is mixed, obtain a kind of feed addictive of promoting the animal and bird intestines physiological function.
Carry out the feeding of broiler test with this additive.With 160 of a collection of Ai Weiyin meat chicks that hatches, be divided into 2 groups, 8 repetitions of every component (cage), 10 in every cage.Two groups of basal diet unanimities, test group are added 0.2% feed addictive of the present invention, and the blank group does not add feed addictive of the present invention.The results are shown in Table 4, table 5.
Table 4 adds the influence of the additive of enhancement intestinal physiology function to fryer intestinal villi height/crypts degree of depth
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
Table 5 adds the additive of enhancement intestinal physiology function to the growth of meat chicken Effect on Performance
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
The result shows, uses feed addictive of the present invention, compares with the blank group, can significantly improve fryer small intestinal mucosa structure; The fryer daily gain improves 14.8%, expects that anharmonic ratio reduces by 10.6%.

Claims (2)

1. the composition of arginine and KG is used to prepare the purposes of the feed addictive of promoting the animal and bird intestines physiological function, it is characterized in that: this feed addictive is that usefulness arginine, two kinds of materials of KG are formulated in proportion, and the mass ratio of arginine and KG is: 0.5~2: 1.
2. purposes according to claim 1 is characterized in that: using method be addition according to feed gross weight meter, be 0.05%~1.0%, directly this product is added in the animal and fowl fodder; Or this product and carrier be mixed and made into pre-mixing agent; Or be mixed and made into premix, the concentrate feed form livestock and poultry of feeding with other feed addictive or feedstuff.
CN2007100532056A 2007-09-13 2007-09-13 Feed additive capable of increasing animal and bird intestines physiological function CN101124943B (en)

Priority Applications (1)

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CN2007100532056A CN101124943B (en) 2007-09-13 2007-09-13 Feed additive capable of increasing animal and bird intestines physiological function

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Application Number Priority Date Filing Date Title
CN2007100532056A CN101124943B (en) 2007-09-13 2007-09-13 Feed additive capable of increasing animal and bird intestines physiological function

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CN101124943A CN101124943A (en) 2008-02-20
CN101124943B true CN101124943B (en) 2010-12-08

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Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102028102A (en) * 2010-12-08 2011-04-27 江南大学 Natural and safe growth-type feed additive
CN102972636A (en) * 2012-12-03 2013-03-20 江苏赛奥生化有限公司 Manufacturing method of feed-grade L-arginine premixing agent
CN103039765A (en) * 2013-01-24 2013-04-17 南京同凯兆业生物技术有限责任公司 Broiler chicken feedstuff additive
CN103168972A (en) * 2013-04-19 2013-06-26 中国水产科学研究院黑龙江水产研究所 Feed capable of enhancing growth performance and protein deposition of carp
CN103340293B (en) * 2013-07-22 2014-05-07 湖南农业大学 Use of alpha-ketoglutaric acid
CN104187112B (en) * 2014-08-27 2016-04-06 南昌傲农生物科技有限公司 A kind of premixed feed by sow feeding enhancing pigling immunity and preparation method thereof
CN105029087A (en) * 2015-08-26 2015-11-11 中国科学院亚热带农业生态研究所 Application of alpha-ketoglutaric acid dipotassium to preparation of pig feed
CN105146230A (en) * 2015-11-02 2015-12-16 云南双胞胎饲料有限公司 Pig feed additive for improving intestinal health and boosting immunity
CN105876174A (en) * 2016-04-14 2016-08-24 中国科学院亚热带农业生态研究所 Sheep feed free of antibiotic addition and preparation method thereof
CN105851621A (en) * 2016-04-14 2016-08-17 中国科学院亚热带农业生态研究所 Chicken feed without antibiotic addition and preparation method thereof
CN105707482A (en) * 2016-04-14 2016-06-29 中国科学院亚热带农业生态研究所 Antibiotic-free cattle feed and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011372A (en) * 2007-02-02 2007-08-08 北京和为康医药科技有限公司 Preparing method of alpha-ketoglutaric acid-arginine salt and its use for treating hepatic disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011372A (en) * 2007-02-02 2007-08-08 北京和为康医药科技有限公司 Preparing method of alpha-ketoglutaric acid-arginine salt and its use for treating hepatic disease

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