CN101116714A - 一种治疗传染性软疣的中药制剂 - Google Patents
一种治疗传染性软疣的中药制剂 Download PDFInfo
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Abstract
本发明涉及一种治疗传染性软疣的中药制剂，它是以土茯苓、生薏苡仁、白僵蚕和马齿苋等10多味中草药为原料。具有清热解毒，燥湿散结的功效。本发明是在传统的中医辨证治疗的基础上结合现代最新科研成果研制而成的。本发明的目的是提供一种治疗传染性软疣的中药制剂。具有疗效确切、安全方便、无毒副作用、价格低廉的特点。
Description
技术领域
本发明涉及一种治疗传染性软疣的中药制剂，是一种治疗传染性软疣以中草药为原料的中药制剂。属于中药领域。
背景技术
传染性软疣是由传染性软疣病毒引起的良性表皮增生性传染性皮肤病。男女发病无差异，可见于任何年龄，但好发于儿童及青年人。四季均可发病，夏秋季节多见。本病属于中医学“鼠乳”范畴，俗称“水瘊子”。本病多由外感风热毒邪，客于肌肤，博结腠理致气血失和而发；或由脾虚中焦失运，后天生化之源不足，肌肤失养，腠理不密，复感外邪，邪毒聚结肌肤而生。《诸病源候论·鼠乳候》记载“鼠乳者，身面忽而生肉，如鼠乳之状，谓之鼠乳也。此亦是风邪博于肌肉而变生也”。中医药治疗本病内外兼治。外治者治其标，内治者治其本。对皮损播散，反复发作者宜扶正祛邪，以调整和增强机体自身抗病能力为要。中医在临床上分风热客表证、脾虚湿困证等症型辨证治疗，取得很好效果。发明一种既安全又有效的中药制剂，具有重大意义。
发明内容
本发明是在传统的中医辨证治疗的基础上结合现代最新科研成果研制而成的。本发明的目的是提供一种治疗传染性软疣的中药制剂。具有疗效确切、安全方便、无毒副作用、价格低廉的特点。
本发明是由下述重量配比的原料药制成的：
板蓝根1.5～6份 败酱草1.0～4份 紫草0.1～2份
马齿苋1.5～6份 大青叶1.0～4份 木贼0.1～2份
土茯苓1.0～4份 连翘1.0～4份 香附0.1～2份
生薏苡仁1.0～4份 生甘草0.1～2份。
本发明的优选配方各原料药的重量配比是：
板蓝根2.5～3.5份 败酱草1.5～2.5份 紫草0.5～1.5份
马齿苋2.5～3.5份 大青叶1.5～2.5份 木贼0.5～1.5份
土茯苓1.5～2.5份 连翘1.5～2.5份 香附0.5～1.5份
生薏苡仁1.5～2.5份 生甘草0.5～1.5份。
本发明的最佳配方各原料药的重量配比是：
板蓝根3份 败酱草2份 紫草1份
马齿苋3份 大青叶2份 木贼1份
土茯苓2份 连翘2份 香附1份
生薏苡仁2份 生甘草1份。
本发明中的药物机理如下：
板蓝根 药性苦，寒。归心、肺、肝、胃经。具有清热，解毒，凉血，利咽的功效。可治疗风热感冒，流感，流脑，乙脑，大头瘟疫，烂喉丹痧，丹毒，痄腮，咽喉肿痛，黄疸，水痘，麻疹等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第1806页)。
马齿苋性味酸、寒。归肝、大肠经。具有清热解毒，凉血止血的功效。可治疗热毒血痢，痈肿疔疮，湿疹，丹毒，蛇虫咬伤，便血，痔血，崩漏下血等。(国家药典委员会编《中华人民共和国药典》2000年版一部第37页化学工业出版社)。
土茯苓 药性甘、淡，平。归肝、肾、脾、胃经。具有清热除湿，泄浊解毒，通利关节的功效。可治疗梅毒，淋浊，泄泻，筋骨挛痛，脚气，痈肿，疮癣，瘰疬，瘿瘤及汞中毒等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第124页)。
生薏苡仁 药性甘、淡，微寒。归脾、胃、肺经。具有利湿健脾，舒筋除痹，清热排脓的功效。可治疗水肿，脚气，小便淋沥，湿温病，泄泻，带下，风湿痹痛，筋脉拘挛，肺痈，肠痈，扁平疣等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第3725页)。
败酱草 药性苦、辛，微寒。归肺、大肠、肝经。具有清热解毒，破瘀排脓的功效。可治疗肠痈，肺痈，痢疾，带下，产后瘀滞腹痛，热毒痈肿等。(《中药大辞典》南京中医药大学编著 上海科学技术出版社 第二版 第1916页)。
大青叶性味苦、寒。归肝、心、胃经。具有清热解毒，凉血消斑的功效。可治疗温病热盛烦渴，发斑发疹，高热神昏，流行性感冒，急性传染性肝炎，菌痢，急性胃肠炎，急性肺炎，丹毒，吐血衄血，黄疸，咽喉肿痛，喉痹，痄腮，口疮，痈疽肿毒，流行性腮腺炎，流行性脑脊髓膜炎，流行性乙型脑炎，上呼吸道感染，钩虫，皮炎，无名热，钩端螺旋体，解铅毒等。(季宇彬主编《抗癌中药药理与应用》黑龙江科学技术出版社1999年版第129页)。
连翘药性苦，微寒。归肺、心、胆经。具有清热解毒，消肿散结的功效。可治疗风热感冒，温病，热淋尿闭，痈疽，肿毒，瘰疬，瘿瘤，喉痹等。(《中药大辞典》南京中医药大学编著 上海科学技术出版社 第二版 第1554页)。
生甘草 药性甘，平。归脾、胃、心、肺经。具有和中缓急，润肺，解毒，调和诸药的功效。可治疗脾胃虚弱，倦怠食少，腹痛便溏，四肢挛急疼痛，心悸，脏躁，肺痿咳嗽；生用治咽喉肿痛，痈疮肿毒，小儿胎毒，及药物、食物中毒等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第792页)。
紫草药性苦、寒。归心、肝经。具有凉血活血，解毒透疹的功效。可治疗吐血，衄血，尿血，紫癜，斑疹，麻疹，黄疸，痈疽，烫伤等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第3272页)。
木贼药性甘、微苦，平。归肺、肝、胆经。具有疏风散热，明目退翳，止血的功效。可治疗风热目赤，目生云翳，迎风流泪，肠风下血，痔血，血痢，妇人月水不断，脱肛等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第482页)。
香附 药性辛、甘、微苦，平。归肝、三焦经。具有理气解郁，调经，安胎的功效。可治疗胁肋胀痛，乳房胀痛，疝气疼痛，月经不调，脘腹痞满疼痛，嗳气吞酸，呕恶，经行腹痛，崩漏带下，胎动不安等。(《中药大辞典》南京中医药大学编著 上海科学技术出版社第二版第2341页)。
本发明遵循中医“君臣佐使”的组方原则，用马齿苋、板蓝根和土茯苓为君药；用生薏苡仁、败酱草、紫草、大青叶、连翘和木贼为臣药；用香附和生甘草为佐使药。诸药相合，共具清热解毒，燥湿散结的功效。治疗传染性软疣具有疗效确切，无毒副作用，服用方便，价格低廉的特点。
本发明药物临床使用结果表明，有如下优点：
1、本发明选用的中草药各组份符合中华人民共和国药品管理法的规定，利用各味中药的综合作用治疗传染性软疣，对人体无毒无害。经动物急、慢性毒性实验表明被实验的动物未见任何毒性反应，其主要脏器也无明显的改变，药物安全可靠。
2、本发明药中富含蛋白质，葡萄糖，葡萄糖醛酸，挥发油，果胶，果糖，有机酸，卵磷脂，维生素，氨基酸，还含皂甙，植物甾醇和钙等多种微量元素，利于人体吸收，增强体质。
3、本发明不仅可有效的治疗传染性软疣，对传染性软疣的预防也有很好的作用，治疗传染性软疣具有疗效确切，无毒副作用，服用方便，价格低廉的特点。
为表明本发明药物对治疗传染性软疣的治疗效果，经临床试验结果如下；治疗传染性软疣患者18例。服用实施例汤剂，每次1袋，一日二至三次，饭前半小时服用。一个月为一个疗程，连续服用三个疗程观察疗效。治愈14例占77.78％，好转3例占16.67％，未愈1例占5.56％，总有效率达94.45％。经三个疗程治疗后，病人无任何不良反应，三大常规化验及肝肾功能检测未发现异常。
具体实施方式
实施例 汤剂 按下述重量称取原料药：
板蓝根3份 败酱草2份 紫草1份
马齿苋3份 大青叶2份 木贼1份
土茯苓2份 连翘2份 香附1份
生薏苡仁2份 生甘草1份。
制备方法是取上述原料洗净去杂，晾干，粉碎成颗粒，加水浸泡1小时，置多功能提取罐中加水煎煮二次，第一次加总药材10倍量的水，煎煮1.5～2小时，取煎液，滤过。第二次加总药材7倍量的水，煎煮1～1.2小时，取两次煎液，滤过，热封袋中，105℃高温灭菌，包装即得。本发明制成的治疗传染性软疣的汤剂为塑封袋装，每袋210ml，口服，一次一袋，每日二至三次。一个月为一个疗程。
Claims (3)
1.一种治疗传染性软疣的中药制剂，其特征在于它是由下述重量配比的原料药制成的：
板蓝根 1.5～6份 败酱草 1.0～4份 紫草 0.1～2份
马齿苋 1.5～6份 大青叶 1.0～4份 木贼 0.1～2份
土茯苓 1.0～4份 连翘 1.0～4份 香附 0.1～2份
生薏苡仁 1.0～4份 生甘草 0.1～2份。
2.根据权利要求1所述的一种治疗传染性软疣的中药制剂，其中各原料药的重量配比是：
板蓝根 2.5～3.5份 败酱草 1.5～2.5份 紫草 0.5～1.5份
马齿苋 2.5～3.5份 大青叶 1.5～2.5份 木贼 0.5～1.5份
土茯苓 1.5～2.5份 连翘 1.5～2.5份 香附 0.5～1.5份
生薏苡仁 1.5～2.5份 生甘草 0.5～1.5份。
3.根据权利要求1所述的一种治疗传染性软疣的中药制剂，其中各原料药的重量配比是：
板蓝根 3份 败酱草 2份 紫草 1份
马齿苋 3份 大青叶 2份 木贼 1份
土茯苓 2份 连翘 2份 香附 1份
生薏苡仁 2份 生甘草 1份。
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101637586B (zh) * | 2009-09-11 | 2011-01-26 | 张云平 | 一种治疗尖锐湿疣的汤剂 |
| CN103961624A (zh) * | 2014-05-14 | 2014-08-06 | 马鞍山科信咨询有限公司 | 一种治疗寻常疣的外用中药 |
| CN107456519A (zh) * | 2017-08-04 | 2017-12-12 | 郭丽娟 | 一种祛疣酊 |
| CN108524716A (zh) * | 2018-06-22 | 2018-09-14 | 高伟玲 | 一种治疗hpv病毒感染的中药组合物 |
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2007
- 2007-08-29 CN CNA2007101209584A patent/CN101116714A/zh active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101637586B (zh) * | 2009-09-11 | 2011-01-26 | 张云平 | 一种治疗尖锐湿疣的汤剂 |
| CN103961624A (zh) * | 2014-05-14 | 2014-08-06 | 马鞍山科信咨询有限公司 | 一种治疗寻常疣的外用中药 |
| CN107456519A (zh) * | 2017-08-04 | 2017-12-12 | 郭丽娟 | 一种祛疣酊 |
| CN108524716A (zh) * | 2018-06-22 | 2018-09-14 | 高伟玲 | 一种治疗hpv病毒感染的中药组合物 |
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