CN100560151C

CN100560151C - Catheterization equipment

Info

Publication number: CN100560151C
Application number: CNB2005800329747A
Authority: CN
Inventors: 拉斯·莫恩森; 马格努斯·W·约兰松
Original assignee: Unomedical AS
Current assignee: Unomedical AS
Priority date: 2004-08-10
Filing date: 2005-08-10
Publication date: 2009-11-18
Anticipated expiration: 2025-08-10
Also published as: CN101031328A

Abstract

Be suitable for being used for the catheterization equipment of the seat element of infusion set as element.This catheterization equipment comprises housing and at least one thin film, described housing and at least one thin film limit the cavity that at least one is suitable for the lancet and means of receiving connector together, catheterization equipment further comprises intubate, this intubate is installed in the described housing and with described at least one cavity fluid and is communicated with, wherein said equipment can be from the lancet and means more than one direction receiving connector, and housing has such geometry, and promptly intubate can be along stretching out from seat element more than one direction.

Description

Catheterization equipment

Technical field

The present invention relates to a kind of catheterization equipment that is used in particular for infusion set.Such equipment can use in various types of infusion sets.

Usually, for example the intermittence of insulin or the infusion set form of successive administration are equipment dimerous to be used for the treatment of material.

Traditional infusion set comprises seat element, and it has and is used to insert the intravital intubate of patient, and described seat element has the device of the adapter intubate that reception stretches out from adapter and makes the adapter intubate form the device that fluid is communicated with the intubate of seat element.Usually, connector pin is communicated with medication (for example insulin pump) fluid.

Background technology

In WO 02/068014 A2, EP 0 956 879 A1, US 5 522 803, US2003/0225373A1 and WO 03/026728A1, various different types of infusion sets are illustrated.

US 2003/0176852A1 discloses infusion set, wherein seat element comprises the parts that pivot, described seat element comprises and is used to insert the intravital intubate of patient, and the parts that pivot have inner chamber, have that a receiving terminal is suitable for receiving the inserter syringe needle or the adapter intubate is used for further being connected with the intubate of seat element with two links (316l and 320).During inserting, the parts that pivot are oriented to perpendicular to seat element, and the thin film in the inserter needle pierces receiving terminal thereby syringe needle pass conduit and pass first link and enter in the intubate, this intubate can be inserted then.After insertion, syringe needle is removed and the parts that will pivot link to each other with adapter.The adapter and the parts that pivot connect from the direction identical with the connection between parts and the inserter of pivoting.The parts that will pivot then rotate so that second link is aimed at intubate.The shortcoming that this equipment has is that the motion of opposing connection axle rotary part is very sensitive, and therefore very little rotation all can stop the conveying of medicine.

WO 02/094352 A2 discloses infusion set, and it has such structure in seat element, and promptly it can be from a direction reception insertion syringe needle and from second direction receiving connector syringe needle.This design does not allow the patient to select him to want which direction to connect adapter and seat element from.

In the infusion set of these prior aries, the structure of intubate and to be used to provide intubate and to be communicated with means from the fluid between the intubate of adapter all be unique for every kind of utensil.Usually, every kind of infusion set also uses the utensil of special guiding and/or locking means, therefore only allows specific adapter to engage with seat element.

If can access general parts, these parts have intubate and are suitable for receiving means from the intubate of adapter, and are suitable for great majority/all common transfusion utensils, from make and practical application on all expect very much.This invention is intended to contain as above-mentioned infusion set and distortion thereof, when such universal component is used to wherein.

Usually, adapter and seat element are connected in the plane that is basically parallel to the carrier skin surface or in the direction that is basically perpendicular to carrier skin.

In addition, in the infusion set of prior art, wish to change into different seat elements for some reason if carry the people of seat element, adapter and seat element all will be replaced.If advantageously dissimilar adapters can use together with identical seat element and vice versa, and if favourable also have that to connect from different perspectives also be possible.

Summary of the invention

Therefore the purpose of this invention is to provide catheterization equipment, it can be used for great majority/all infusion sets as component part, and it can be for from the usefulness more than the connection of a direction.

According to the present invention, provide the catheterization equipment that is used for infusion set to be used to be installed in seat element, comprise housing and at least one thin film, this the two limit the cavity that at least one is suitable for the lancet and means of receiving connector, catheterization equipment further comprises intubate, this intubate is installed in the described housing and with described at least one cavity fluid and is communicated with, described equipment can be from the lancet and means of the first receive direction receiving connector, and in addition can be from the described lancet and means of the second receive direction receiving connector that is different from described first direction, between the lancet and means of adapter and at least one cavity, provide fluid to be communicated with.Described apparatus characteristic is that catheterization equipment has device, and this device is used for catheterization equipment is attached to the related device of seat element, and housing has such geometry, and promptly intubate can be along stretching out from seat element more than one direction.

The advantage of such element is, it can be used as critical component in infusion set, and the Skin observing of carrier is parallel to and perpendicular to the connection between adapter and the seat element relatively.Like this, this critical component can mass production and be used as parts in a series of desired design of infusion set.This can cause low manufacturing cost, production line and more nimble product more flexibly.

Can make intubate along the suitable shape of stretching out from seat element more than one direction for for example cuboidal housing of cardinal principle or have at least two lateral cuboidal housings.Such cube housing can be used the intubate orientation, points to a plurality of directions in same hole.Another kind of suitable geometry is the section of spheroid, and this section is limited by two tangent planes in the spheroid, perhaps ellipsoidal section, and this section is limited by ellipsoidal two tangent planes.Preferably, the angle between the tangent plane in spheroid and the ellipsoid between the 60-120 degree, particularly preferably be angle for roughly 90 the degree.In addition, suitable housing can be the shape of cylindrical shape or box, and described housing can be attached to base in the mode that allows its rotation.

Be stressed that, do not force when being attached to seat element, can obtain a plurality of sensings, also can be derived from the probability of a plurality of attached directions.

In a preferred embodiment, but catheterization equipment is attached on the seat element, thereby allows its exchange with delivery mode.Described exchange can be implemented by taking catheterization equipment away, and for example the guiding by complete guiding device is with the catheterization equipment seat element that slips away.Then, another catheterization equipment can be equipped in the identical seat element, this is that to rely on be to use different guiding devices that catheterization equipment is slipped into the appropriate location under the different directed situation of soft intubate to realize by same set of guiding device or expectation.Thus obtained advantage is to save medical expense thereby seat element can be repeatedly used by the patient.In addition, provide the selection of using different catheterization equipments in the same base element, for example having different cannula size is different length and/or this equipment of diameter, makes infusion set be fit to use the patient of building block thus.

The invention still further relates to seat element, it has many cover guiding devices so that it can be connected with the catheterization equipment of the above-mentioned type, and ways of connecting is that catheterization equipment has more than its possible main shaft direction.In a preferred embodiment, seat element further has retainer, it is last that described retainer can make catheterization equipment stop at apart from a plurality of height of bottom position and/or distance, thereby can make infusion set can use same catheterization equipment and have multiple intubate length of exposure (thrusting patient's intubate part).

In a preferred embodiment, can catheterization equipment be installed in the seat element, thereby the selection that changes the intubate insertion depth is provided with different levels.The advantage that provides like this is, catheterization equipment and seat element can insertion depths that be used from more than, thereby further make infusion set adapt to different separately patients, and further can for example be used for child and adult as infusion set.

In addition, different insertion angles can be used for identical seat element.By being transformed into catheterization equipment, use same seat element just may obtain insertion angle more than one with second angle between intubate and housing from catheterization equipment with first angle between intubate and housing.

In another preferred embodiment, catheterization equipment is provided with guiding device, be used to guide with adapter be connected and/or be used to guide assembling with seat element.In preferred embodiment, catheterization equipment has more than the guiding of a type and/or locking device.The bonding position that this just can make the patient can use him or she to have a preference for, for example the combination of some patient's preference is for connecting the combination of the patient preference parallel and other with skin perpendicular to skin.

Above-mentioned guiding device be used to guide bonded, thereby syringe needle and/or intubate end are fixed on correct position and place, or be used for the guide cannula equipment to the base element.

In a preferred embodiment, guiding device is the assembling of guide cannula equipment and seat element both, and also guiding and adapter and/or inserter combines.

Preferably, catheterization equipment is suitable for and can be attached to removedly on the seat element of infusion set.

Preferably, the form of the lancet and means of adapter is an intubate.

In a preferred embodiment, but locking device be used for adapter and seat element being locked together with delivery mode.

The infusion set that has the mentioned kind catheterization equipment provides unique selection for the patient.Can insert intubate with traditional inserter now, vertically provide predetermined inlet of thrusting the degree of depth, and can be parallel to the state connection of skin surface, the infusion set of low gabarit is provided with adapter with respect to skin.

In a preferred embodiment, catheterization equipment is soft intubate, and preferably, soft intubate is made by plastic material.The preferred plastic material that is used for soft intubate is enough pliable and tough so that crooked and enough firm to avoid being entangled with the material that inaccessible firmly medicine is supplied with when the patient moves.In addition, described material must be compatible with medical application, promptly must keep minimum and nontoxic to the stimulation of skin, must not can decompose in vivo etc.Thermoplastic elastomer (TPE) is the material type that satisfies these requirements.Being exemplified as of such useful elastomers: polyester ether, ECDEL, styryl TPE, alkylene TPE, polyurethane-base TPE, ester group TPE, amide groups TPE, polyolefin and silicone rubber.In a preferred embodiment, material is selected from polypropylene, C-FLEX ^TM, C-FLEX ^TMWith polypropylene, LUPOLEN ^TM1840H, LUPOLEN ^TM3020D, PELLETHANE ^TM2363-75D, PELLETHANE ^TM2363-55D, TECOTHANE ^TMAnd CARBOTHANE ^TMMixture.

In a preferred embodiment, housing is made by plastic material, preferably polypropylene.

In a preferred embodiment, receive between first and second directions of described syringe needle and/or lancet and means and have at least 45 ° angle, has at least 60 ° angle between more preferably described direction, even have at least 75 ° angle between more preferably described direction, have at least 85 ° angle between most preferably described direction.

In preferred embodiment, except above-mentioned both direction, catheterization equipment can receive lancet and means from more direction, and described more direction preferably has 5 °-175 ° angle with respect to first direction, more preferably 30 °-150 ° angle.

In the preferred embodiment of catheterization equipment, thin film is arranged, thereby the lancet and means that this thin film can be pierced and sealed packet surrounds adapter can be communicated with in catheterization equipment with at least one the cavity fluid that is used for each receive direction.

In a further advantageous embodiment, a thin film is arranged, no matter use which possible receiving angle, the intubate of adapter and/or insertion syringe needle can both pierce through this thin film.

In a preferred embodiment, catheterization equipment comprises that a plurality of pits are used for the lancet and means of receiving connector.These pits are communicated with the intubate fluid of catheterization equipment.

In a further advantageous embodiment, catheterization equipment rotates with respect to seat element, so just can insert behind the rotating base element and need not move the intubate of having inserted.Selectively, seat element is turned to desired angle with respect to intubate, preferably use inserter that intubate is inserted then.

In a preferred embodiment, by hinge catheterization equipment is attached on the seat element.

In a preferred embodiment, catheterization equipment comprises chamber, and when adapter was connected to seat element, this chamber was communicated with the lancet and means fluid of adapter, and described chamber also is communicated with the intubate fluid of catheterization equipment.Have chamber and make that the connection of regulating between adapter and the seat element is easier.

In a further advantageous embodiment, the lancet and means of adapter is communicated with the direct fluid of the intubate of catheterization equipment, does not promptly have chamber.Advantage with less dead volume so just is provided.

In a preferred embodiment, thin film is by silicones, and more preferably the self sealss silicones is made.

In a preferred embodiment, thin film intersects with the axis of intubate.

An alternative embodiment of the invention relates to infusion set, and this infusion set comprises the catheterization equipment of the above-mentioned type.Catheterization equipment can be attached to seat element, utilizes for example mechanical means, resembles wheel rim, groove or cock; Utilize binding agent such as adhesive, or utilize for example frictional force, catheterization equipment to connect in the hole in seat element, and the sidewall in hole and the friction between the catheterization equipment remain on the appropriate location with catheterization equipment.In a preferred embodiment, seat element has the first cover locking device, and catheterization equipment has the second cover locking device, is used for catheterization equipment is fixed on seat element.Preferably, locking device also has disengaged part and is used for catheterization equipment is discharged from seat element.

In the preferred embodiment of infusion set, adapter comprises intubate, and this intubate can rupture in the predetermined area.So just adapter might be inserted the intubate of catheterization equipment as inserter.After inserting, the intubate of adapter is then used adapter in a conventional manner in the fracture of the place of expectation.

A second aspect of the present invention relates to infusion set, this infusion set comprises seat element, this seat element comprises the catheterization equipment of the above-mentioned type, be used to thrust in patient's body, and adapter, be used for connecting seat element and armarium by conduit, described adapter comprises the lancet and means of adapter, is communicated with described pipe fitting fluid; Seat element selectively comprises the first cover guiding device and the first cover locking device, is used for adapter is locked onto seat element; Described adapter selectively comprises the second cover guiding device, and it is suitable for connecting and the second cover locking device with the first cover guiding device, and it is suitable for releasably overlapping the locking means for engaging with first.

According to another aspect of the present invention, provide infusion set.This infusion set comprises seat element and is connected to catheterization equipment on the seat element removedly.Catheterization equipment comprises housing, and at least one thin film is fixed on this housing and is installed in intubate on the housing.Catheterization equipment is suitable for being communicated with by fluid between the intubate of lancet and means and catheterization equipment from first receive direction with from the lancet and means of the second receive direction receiving connector that is different from first direction.

Description of drawings

To be described in further detail catheterization equipment with reference to the accompanying drawings.

Fig. 1 is the perspective view of catheterization equipment embodiment of the present invention;

Fig. 2 is the zoomed-in view of the housing of catheterization equipment shown in Fig. 1;

Fig. 3 is the profile of catheterization equipment shown in Fig. 2;

Fig. 4 is the perspective view of the catheterization equipment that is connected with inserter;

Fig. 5 is mounted in the perspective view of the catheterization equipment in the seat element of infusion set;

Fig. 6 is mounted in the decomposition diagram of the catheterization equipment in the seat element;

Fig. 7 is mounted in the seat element and the vertical view of the catheterization equipment that protected parts are sealed;

Fig. 8 is an exploded top perspective view, shows the catheterization equipment that is installed in the seat element, and wherein intubate is basically perpendicular to the principal plane of seat element;

Fig. 9 is the side view of the inserter that is connected with embodiment shown in Fig. 8;

Figure 10 is a perspective view, shows the installation of catheterization equipment in seat element;

Figure 11 is a decomposition side view, shows the another location that is installed in the catheterization equipment in the seat element;

Figure 12 is an exploded view, shows the embodiment of Figure 11 from different angles;

Figure 13 is the exploded view of catheterization equipment, and this catheterization equipment is installed in the seat element of second type, comprises inserter and guard block;

Figure 14 is mounted in the exploded view of the catheterization equipment in the seat element shown in Figure 13, and wherein catheterization equipment is vertically installed;

Figure 15 is the birds-eye perspective that has the catheterization equipment of guard block in seat element;

Figure 16 is the profile of embodiment shown in Figure 15;

Figure 17 is the exploded view with embodiment shown in Figure 14 of different guard blocks;

Figure 18 is the perspective view of the embodiment of catheterization equipment, seat element and inserter;

Figure 19 is the perspective view that has embodiment shown in Figure 18 of inserter in vertical direction;

Figure 20 is the perspective view of embodiment shown in Figure 18, and inserter is removed;

Figure 21 is the birds-eye perspective of embodiment shown in Figure 18, and guard block engages with seat element;

Figure 22 A shows the catheterization equipment of Fig. 1;

Figure 22 B-D shows the catheterization equipment of Figure 22 A, and this catheterization equipment has various guard blocks;

Figure 23 A-D shows the side view of embodiment shown in Figure 22 A-D;

Figure 24 A-D shows the vertical view of embodiment shown in Figure 22 A-D;

Figure 25 is the perspective view of the embodiment of the invention, and this embodiment has guard block;

Figure 26 is the profile of embodiment shown in Figure 25;

Figure 27 is the exploded view of the embodiment of the invention, and this embodiment includes adhesive linkage;

Figure 28 is the exploded bottom view of embodiment shown in Figure 27;

Figure 29 A is another embodiment of the real catheterization equipment of invention;

Figure 29 B is the part sectioned view of embodiment shown in Figure 29 A;

Figure 30 A is the front perspective view of catheterization equipment and adapter;

Figure 30 B is the birds-eye perspective of embodiment shown in Figure 30 A;

Figure 31 A is the decomposition plan view of catheterization equipment, seat element and adapter;

Figure 31 B is the catheterization equipment of embodiment shown in Figure 31 A and the perspective view of seat element;

Figure 32 A is the profile of embodiment shown in Figure 31 A;

Figure 32 B is the profile of embodiment shown in Figure 31 B;

Figure 32 C is the side view of embodiment shown in Figure 31 B;

Figure 32 D is the vertical view of embodiment shown in Figure 31 B;

Figure 33 A is the perspective view of catheterization equipment shown in Figure 31 B, and catheterization equipment is in vertical direction;

Figure 33 B is the perspective view of catheterization equipment shown in Figure 31 A, and catheterization equipment is in vertical direction;

Figure 33 C and D show the vertical view of embodiment shown in Figure 33 A and the B respectively;

Figure 34 A is the front perspective view of catheterization equipment embodiment;

Figure 34 B is the perspective view of the embodiment of catheterization equipment, seat element and adhesive linkage;

Figure 35 is the profile of embodiment shown in Figure 34 B;

Figure 36 A-E is the vertical view and the perspective view of the embodiment of the invention;

Figure 37 A is the birds-eye perspective of catheterization equipment and adapter, demonstrates intubate and is in vertical direction;

Figure 37 B is the side perspective view of embodiment shown in Figure 37 A;

Figure 37 C is the vertical view of embodiment shown in Figure 37 A;

Figure 38 A is the side perspective view of catheterization equipment and adapter, demonstrates intubate and is in parallel direction;

Figure 38 B is the vertical view of embodiment shown in Figure 38 A;

Figure 39 perspective view shows the inserter that has catheterization equipment;

Figure 40 A and B are perspective views, show catheterization equipment and are installed in the adapter in different positions;

Figure 41 A and B are respectively the profiles of embodiment shown in Figure 40 A and the B;

Figure 42 A and B are respectively the side views of embodiment shown in Figure 41 A and the B;

Figure 43 is the profile of catheterization equipment embodiment of the present invention, demonstrates adapter and is connected with intubate;

Figure 44 is the birds-eye perspective of catheterization equipment, seat element and adapter, shows locking device;

Figure 45 is the vertical view of the embodiment of the invention;

Figure 46 is the birds-eye perspective of catheterization equipment, seat element and inserter;

Figure 47 is that catheterization equipment and inserter vertically are installed in the perspective view on the seat element;

Figure 48 shows inserter, and this inserter can be installed on the catheterization equipment;

Figure 49 is the perspective view of the embodiment of the invention, shows seat element with angle;

Figure 50 is mounted in the vertical view of the catheterization equipment in the seat element with angle;

Figure 51 is the profile of embodiment shown in Figure 50;

Figure 52 is the front perspective view of embodiment shown in Figure 50;

Figure 53 is the birds-eye perspective of embodiment shown in Figure 50;

Figure 54 is the perspective view of embodiment shown in Figure 50;

Figure 55 is the perspective view of embodiment shown in Figure 50;

Figure 56 is the perspective view of embodiment shown in Figure 50;

Figure 57 is the front perspective view of embodiment shown in Figure 50;

Figure 58 is the decomposition diagram of another embodiment of the present invention;

Figure 59 is the decomposition diagram of catheterization equipment shown in Figure 58 and seat element;

Figure 60 is the perspective view of embodiment shown in Figure 59, and catheterization equipment is in vertical direction;

Figure 61 is the perspective view of embodiment shown in Figure 60, and catheterization equipment is in parallel direction;

Figure 62 is the decomposition diagram of embodiment shown in Figure 61;

Figure 63 is the decomposition diagram of embodiment shown in Figure 61; With

Figure 64 is the profile of catheterization equipment shown in Figure 58.

Figure 65 shows the section of spheroid, and this section is limited by two facets.

The specific embodiment

Fig. 1 shows the first embodiment of the present invention.In this embodiment, catheterization equipment 1 comprises housing 2 and thin film 3, and they limit cavity 6 jointly, and this cavity is suitable for admitting the lancet and means that stretches out from adapter.Intubate 4 is installed in the housing 2 and with cavity 6 fluids and is communicated with.Thin film 3 can have ellipse or strip shape, at least a portion in two

sides

8,10 of covering catheterization equipment 1.Also thin film 3 can be configured to selectable shape, for example but be not limited to circle, rectangle, triangle and other shape.This provides possibility for adapter from the connection more than an angle.Thin film 3 is shown as single thin film, and it is around cavity 6 bendings.Selectively, can be on different receive directions for the inlet of lancet and means provides thin film more than one, as described below.

In the embodiment shown in fig. 1, guiding device 5 is set on the housing 2, guides with for example adapter, inserter or this two such equipment with this to be connected.This helps to guarantee suitably to aim at from the two intubate of adapter, adapter syringe needle or this, and is as described below.As illustrated in fig. 1 and 2, and as described below, and guiding device 5 can connect from least two orthogonal substantially angle guiding.

Fig. 2 shows the cavity 6 that is limited by housing 2 and thin film 3.Cavity 6 can be communicated with intubate 4 fluids.As shown in the figure, paired guiding device 5 extends out from housing 2, opposes mutually on the side 9,11 of housing 2.Each guiding device 5 can comprise paired microscler track component 12, is suitable for being slidably engaged with the such equipment of for example adapter or inserter, and is as described below.Each track component 12 can further comprise notch 14, and this notch is limited at and is used for engaging removedly other or identical equipment in the track component 12.Those skilled in the art will be clear, and other guiding device 5 can be used for engaging with the removable of equipment, and described equipment resembles adapter, for example forms infusion set, perhaps inserter.

The profile of the catheterization equipment 1 shown in Fig. 3 further shows in detail cavity 6.Cavity 6 limits chamber 16, and this chamber is communicated with intubate 4 fluids.Lancet and means (following such lancet and means 580,680) can any position on thin film 3 penetrates thin film 3 and is communicated with chamber 16.Therefore, the lancet and means resemble the lancet and means can be communicated with intubate 4 fluids of equipment 1, thereby adapter is linked to each other with catheterization equipment 1 from different angles become possibility.As shown in Figure 3, catheterization equipment 1 can further comprise the

admission passage

17 and 19 of intubate 4.Each

passage

17 and 19 can be communicated with chamber 16 fluids, is used for the treatment of the reception of material by lancet and means.Selectively,

admission passage

17 and 19 can directly admit lancet and means to be used for the treatment of the conveying of material, and is as described below.

As shown in Figure 4, catheterization equipment 1 is connected on the inserter 50.Syringe needle 51 extends from inserter 50, penetrates thin film 3 and stretches out by intubate 4 in primary importance.It is subcutaneous to use inserter 50 that the intubate 4 of equipment 1 is inserted the patient.After insertion, inserter 50 is removed and intubate 4 is left on and is used for the delivering therapeutic material in patient's body and extracts out after a while, for example, and when the two is removed when seat element (shown in Fig. 5), catheterization equipment 1 or this.Fig. 4 shows inserter 50 can be connected to catheterization equipment 1 from first direction of insertion 18, and this first direction of insertion is basically parallel to or aims at the axis 103 of intubate 4.The part of thin film 3 is held in and can enters, and so just explanation may be connected to adapter from the second direction 20 that is different from first direction 18.As shown in the figure, the angle between the both direction 18,20 is approximately 90 °.First direction 18 and second direction 20 can pre-determine by the location that enters chamber 17 and 19, in order to the reception of guided puncture parts.Selectively, can use, thereby the fluid between the intubate 4 of permission lancet and means and catheterization equipment is communicated with the delivering therapeutic material for chamber 16 any receive directions.By example, the other angle between first direction 18 and the second direction 20 is possible.Preferably, the angular range between first direction 18 and the second direction 20 is from about 5 ° to about 175 °, more preferably from about 30 ° to about 150 °.Preferably, the angle between first direction 18 and the second direction 20 is about at least 45 °, more preferably about 60 °, 75 °, 85 °, and most preferably about 90 °.It will be apparent to those skilled in the art that other closure is possible and is from many different angles.

As shown in Figure 5, catheterization equipment 1 is assembled in the seat element 100 of infusion set 90.In this embodiment, seat element 100 comprises base guiding device 101, and this base guiding device connects together with the guiding device 5 that is installed on the housing 2 of catheterization equipment 1.Guiding device 5 on the catheterization equipment 1 can be used for catheterization equipment 1 guiding and is aligned in the base guiding device 101 of seat element 100, and will connect guiding to adapter.Opening 102 in the part of the base guiding device 101 of seat element 100 can be used for the guiding device 5 of catheterization equipment 1 or resembles adapter or the connection of the equipment that inserter is such, direction is from the second direction except first direction 18 20, and first direction 18 is parallel to the axis 103 of intubate 4.Guiding device 5 can be elongated rectangular rail, and is as shown in this embodiment, perhaps pin, or the known alignment mechanism of other type.

Guard block 104,105 is illustrated in Fig. 5.Guard block 104,105 is protected on a plurality of sides and is sealed and cover catheterization equipment 1 to small part.Guard block 105 comprises lead arm 106 and lock arm 107, and is similar with lock arm to the guiding that may be arranged on the adapter.At U.S.5, the lock arm that discloses adapter in 522,803 in detail engages with the exemplary of infusion set, is incorporated herein by reference by integral body this its.Lead arm 106 is suitable for connecting with cooperating opening 110, and this cooperation opening 110 is formed in the inserter 50, as illustrated in Figures 5 and 6.

That Fig. 6 shows is selectable, the perspective view of embodiment shown in Fig. 5.Selectively, lead arm 106 can connect with the guiding device 101 of base 100, as shown in Figure 8, shows inserter 50 and has been removed.Lock arm 107 removable turning up the soil engage the opening 114 that is formed on base 100.Catheterization equipment 1 can be for the usefulness of transposing seat element 100 and catheterization equipment 1 with removable joint of seat element 100.For example, but be not limited to following content,, catheterization equipment 1 can be removed from seat element 100 by catheterization equipment 1 is skidded off seat element 100.Use the identical lead arm 106 of seat element 100 another catheterization equipment 1 can be slided in the same seat element 100.Advantage of the present invention is that same seat element can be reused repeatedly by the patient, has so just saved medical expense.In addition, interconvertible catheterization equipment and seat element can for example, but be not limited to for the usefulness of using different catheterization equipments in same seat element, and catheterization equipment has different size intubate 4, that is, and and the length of intubate 4 or diameter.Such transposing allows infusion set to be made into external member, and to satisfy the patient required by using these to make standard-sized element.

Fig. 7 shows catheterization equipment 1 and is installed on the seat element 100 by removable turning up the soil, and catheterization equipment 1 and base 100 protected

parts

104 and 105 cover.

Fig. 8 shows catheterization equipment 1 and is installed in the seat element 100, but is in the chosen position shown in Fig. 5-7.Particularly, catheterization equipment 1 is installed on the second direction 20, and wherein intubate 4 is installed on the seat element 100, is basically perpendicular to the principal plane 118 of seat element 100.Seat element 100 comprise a plurality of guiding devices 105 with opening 102 so that can carry out on these a plurality of orientation at least removable connection of catheterization equipment 1.As shown in Figure 8, the guiding device 5 of housing 2 and opening 102 removable the turning up the soil on the seat element 100 connect.The orientation that changes the guiding device 5 of housings 2 with respect to the guiding device on the seat element 100 101 and opening 102 can make the angle change between intubate 4 and the seat element 100, and this may expect in some cases.When the guiding device 5 of housing 2 was received in the opening 102 of seat element 100 slidably, guard block 104,105 also can engage with seat element 100.

As shown in Figure 9, in conjunction with Fig. 8, when catheterization equipment 1 was received in the opening 102 in the seat element 100 slidably, the inserter 50 that includes the syringe needle 51 that extends through intubate 4 was connected to catheterization equipment 1.Guard block 104,105 also engages with seat element 100.Selectively, adapter (adapter 450,550,650 that for example, describes below) can engage and be connected on the catheterization equipment 1 with seat element 100 in position that inserter 50 is illustrated or in the position that guard block 105 is illustrated.As shown in Figure 9, catheterization equipment 1 (is compared the parallel direction shown in Fig. 7) in vertical direction with inserter 50 and is engaged with seat element 100.

In Figure 10, catheterization equipment 1 is installed in and is in first direction 18 in the seat element 100, and intubate 4 is substantially parallel with the principal plane 118 of seat element 100 in the case.Frictional force between the guiding device 5 of dependence catheterization equipment 1 and the guiding device 101 of seat element 100, catheterization equipment 1 is retained in the seat element 100 slidably.When catheterization equipment 1 engaged with base 100, the lead arm 106 of guard block 105 was slidably engaged in the opening 122 that is formed at base 100.Can also use several methods that catheterization equipment 1 is engaged with seat element 100 for a person skilled in the art.For example, but be not limited to, mechanical means resemble wheel rim, groove or cock; Utilize binding agent to resemble adhesive, or utilize for example frictional force, the opening 102 in catheterization equipment 1 and the seat element 100 connect and the side of the side of the guiding device 5 by catheterization equipment 1 and opening 102 between frictional force remain there.Seat element 100 can further comprise locking device, and described locking device is fixed on catheterization equipment 1 in the seat element 100 removedly.In addition, catheterization equipment 1 can have locking device, resembles the engagement slot 14 shown in Fig. 2, is used for catheterization equipment 1 is fixed on seat element 100.Locking device can comprise further that disengaged part is used for release locking device.

Figure 11 and 12 shows the lock arm of guard block 105 or alternatively has the adapter of similar lock arm (as shown in Figure 52-57) and how can be bonded in the opening 107 in the seat element 100.Demonstrate intubate 4 and on parallel direction, extend, similar to Fig. 7.

Preferably, catheterization equipment 1 of the present invention is made by following material, but is not limited thereto the described material in place.Those skilled in the art will appreciate that other material also is possible and within the scope of the invention.

The housing 2 of catheterization equipment 1 of the present invention is preferably made by plastic material, more preferably polypropylene.Thin film of the present invention is preferably made by silicones, more preferably the self sealss silicones.Thin film surrounds lancet and means so that can be communicated with the intubate of catheterization equipment or with at least one cavity fluid on each receive direction preferably suitable for being punctured parts and piercing through and seal.

Go out the preferably soft intubate of the intubate 4 of catheterization equipment 1 as shown.Preferably, intubate 4 is made by plastic material.The preferred plastic material that is used for soft intubate 4 also is enough pliable and tough so that crooked and enough firm to avoid twisting together and to seal the material that medicine is supplied with when the patient moves.Further, described material should meet medical application, i.e. Zui Xiao skin irritation, nontoxic, nondecomposable etc. in vivo.Thermoplastic elastomer (TPE) is the type of material that satisfies these requirements.Such elastomer example includes, but are not limited to: polyester ether, ECDEL, styryl TPE, alkylene TPE, polyurethane-base TPE, amide groups TPE, polyolefin and silicone rubber.In a preferred embodiment, material is selected from polypropylene, C-FLEX TM, C-FLEXTM and polypropylene, LUPOLEN TM 1840H, LUPOLEN TM 3020D, PELLETHANE TM 2363-75D, PELLETHANE TM 2363-55D, the mixture of TECOTHANE TM and CARBOTHANE TM.

Alternate embodiments of the present invention is illustrated in Figure 13-25, and the same cannula equipment 1 that is installed in the dissimilar seat element 200 has been described.Figure 13-25 has shown that how the catheterization equipment of Fig. 1-12 can be installed in the dissimilar infusion sets, has illustrated the advantage of catheterization equipment of the present invention.

As shown in figure 13, catheterization equipment 1 engages with seat element 200 along first direction 18, and intubate 4 is basically parallel to the principal plane 218 of seat element 200 in this case.Figure 13 also shows inserter 50 and is connected to catheterization equipment 1 and extends through intubate 4 with syringe needle 51.Projection 22 is extended and is engaged slidably with the guiding device 5 of catheterization equipment 1 from inserter 50.

In this embodiment, seat element 200 comprises guiding device 201, and the guiding device 5 on described guiding device 201 and the catheterization equipment 1 connects together, as mentioned above.Intubate 4 extends through the opening 203 in the seat element 200, and the size of opening 203 is made into the intubate ring 210 that can admit catheterization equipment 1.Seat element 200 further comprises the guiding device 206,207 of setting, and described guiding device 206,207 is suitable at inserter 50 by the guiding device 208,209 of the corresponding guard block 204 of reception that slides when catheterization equipment 1 removes.When intubate 4 was fixed in patient's the skin and can therapeutant be flowed to the patient by intubate 4, guard block 204 can cover catheterization equipment 1.Can in Figure 16, be clear that guiding device 208,209; herein; the guiding device 206,207 of seat element 200 and the guiding device 208,209 of guard block 204 are suitable for rotatably connecting being in the same place, thereby guard block 204 is fixed to seat element 200 removedly.Preferably, guiding device 207,208 can comprise further that the projection 211 of being with barb is so that engage.Guiding device 206,209 also can comprise the projection 111 of being with barb.As shown in figure 13, seat element 200 preferably includes the guiding device 206,207 of two settings, is positioned on the opposite flank of seat element 200.Selectively; can use the guiding device 206,207 of any amount or only engage corresponding guiding device 208,209 or guiding device 208 respectively with guiding device 207, guiding device 206,207 and 208,209 can be the virtually any size that is enough to guard block 204 is fixed to removedly seat element 200.Other aligning, locking and/or guide can be provided.

Guard block 204 can comprise opening 212, can be clear that in Figure 15.Can draw together opening 212 with being used for the pipe fitting (not shown) that therapeutant is transported to catheterization equipment 201 inserted to pass, thereby when lid is on the seat element 200, therapeutant can be flowed to the patient by intubate 4.Guard block 204 can further comprise elongated opening 214, is positioned at the opposite flank of guard block 204.Preferably, opening 214 extends internally and goes along the profile of periphery 216 substantially from the periphery 216 of parts 204.The guard block side 218 of adjacent openings 214 provides the partially flexible surface to be used for grasping and has rotated guard block 204 so that engage or release base member 200.Yet, one skilled in the art would recognize that and can realize alternative joint and release by the common known any mechanism of those skilled in the art.

Figure 14 shows catheterization equipment 1, and it engages with seat element 200 along second direction 20, and intubate 4 is basically perpendicular to the principal plane of seat element 200 in the case.Figure 14 has also shown inserter 50, is connected to catheterization equipment 1 and extends through intubate 4 with syringe needle 51.The joint of inserter 50 and guard block 204 is as in the above described in Figure 13.In case inserter 50 is removed from catheterization equipment 1 and seat element 200, guard block 204 just can engage with the guiding device 206,207 of seat element 200, as shown in figure 15.In some embodiments, guard block can engage with seat element, and inserter also engages with seat element simultaneously, and is as described below.In the embodiment shown in fig. 15, intubate 4 is extended from the bottom of base 200.As mentioned above, pipe fitting can extend from opening 212.

Figure 16 shows the profile of equipment shown in Figure 15, and herein, guard block 204 engages with seat element 200, and catheterization equipment 1 is positioned in the seat element 200, and intubate 4 is stretched out principal plane 218 perpendicular to seat element 200 from seat element.The size and dimension that guard block 204 is made into can connect with seat element 200.

The guiding device 207 of seat element 200 and the guiding device 208 of guard block 204, the projection 211 of footprint band barb is shown as rotatably being fixed together on the paired guiding device 207,208 in inside.As mentioned above and as shown in figure 16, outside paired guiding device 207,208 does not comprise the projection 211 of being with barb, yet those skilled in the art will appreciate that in the guiding device 207,208 each can comprise the projection 211 of being with barb.The

admission passage

17 and 19 of catheterization equipment 1 is positioned under the thin film 3, is protected the protection of parts 204.

Figure 17 shows identical catheterization equipment 1, its guiding device 5 by being inserted into the catheterization equipment 1 in the base guiding device 201 engages with identical seat element 200, at this, intubate 4 is extended along first direction 18, is basically parallel to the principal plane 218 in seat element 200.Figure 17 shows paired guard block 250,252, thereby they can engage covering catheterization equipment 1 and seat element 200 with seat element 200.The size and dimension that guard block 250,252 is made into can connect together with covering base element 200 with seat element 200.As mentioned above, the alternative shape of seat element 200 and guard block 250,252 also is possible.Other structure that these a plurality of elements are combined together also can be used.

Guard block 250 comprises paired guiding device 254, and described guiding device 254 can be suitable for engaging the guiding device 207 of seat element 200.As mentioned above, seat element 200 can comprise guiding device 206.Guiding device 206 can slide on the periphery 258 of guard block 250 with projection 256.Guard block 250 can further comprise notch 260, is used to engage the edge 270 of seat element 200.Guard block 250 has covered the part of the thin film 3 of catheterization equipment 1; and when seat element 200 is attached on the skin the patient and intubate 4 when being used for the treatment of mass transport via the skin location, thereby guard block 250 can also splice protection parts 252 covering base elements 200.As shown in figure 17, guard block can comprise the part 264 of the thin film 3 that is used to cover catheterization equipment 1, and this part 264 can be by being different from guard block remainder and can be by syringe needle, the syringe needle 51 of inserter 50 for example, and the material that pierces through is made.For example, part 264 can one-body moldedly form on guard block 250 and by elastomer.Guard block 252 engages with guard block 250 slidably.

Figure 18 shows the guard block 250 that engages with seat element 200, described in top Figure 17.When guard block 250 engages with seat element 200, guard block 252 can be removed from guard block 250 and seat element 200.The syringe needle 51 of inserter 50 can be inserted in the thin film 3 of catheterization equipment 1 and along first direction 18 and extend through intubate 4.Inserter 50 can be removed and replace with guard block 252, perhaps selectively uses adapter, resembles following adapter 450,550,650, is used for the treatment of the conveying of material.

Figure 19 shows catheterization equipment 1 (under guard block 250,252), and it engages with seat element 200 along second direction 20, and inserter 50 makes syringe needle 51 along passing intubate 4 in the second direction insertion catheterization equipment 1.Figure 19 demonstrates the part 264 that syringe needle 51 pierces through guard block 250.When catheterization equipment 1 when second direction 20 engages with seat element 200, guard block 250,252 can keep engaging with seat element 200, thus when the syringe needle 51 of inserter 50 extends through intubate 4 protection seat element 200 and catheterization equipment 1.

Figure 20 shows the embodiment of above-mentioned Figure 17, demonstrates that guard block 250 engages with seat element 200 and guard block 252 also engages.Go out as shown, guard block 252 can engage from the direction that seat element 200 stretches out along being parallel to intubate 4.Figure 21 shows the compact size of described equipment when guard block 252 engages with guard block 250 and seat element 200.In this form, more sensing elements of equipment are covered and are protected, and assembly itself is easy to transportation and packing.As mentioned above, guard block 252 can be removed and adapter can be inserted and substitute guard block 252, have similar compact size.

Figure 22 shows the perspective view of catheterization equipment 1, and comprises several assembly forms, comprises seat element 100,200 and guard block 104,105,204,250,252.It is own that Figure 22 A shows catheterization equipment 1.Figure 22 B catheterization equipment 1 is inserted in the seat element 100.Guard block 104,105 covers seat element 100 and catheterization equipment 1, and while to small part thin film 3 can be accepted the insertion of inserter or adapter syringe needle so that the delivering therapeutic material.

Figure 22 C shows catheterization equipment 1, and it engages with seat element 200.Demonstrate guard block 204 and cover catheterization equipment 1 and seat element 200, address above.

Figure 22 D shows catheterization equipment 1, and it engages with seat element 200, and guard block 250,252 covers catheterization equipment 1 and seat element 200.

Figure 23 A-D shows the side view of catheterization equipment 1, described catheterization equipment 1 be different from the embodiment shown in Figure 22 B-D accordingly and engage.

Figure 24 A-D shows the vertical view of the embodiment shown in Figure 22 B-D respectively.

Figure 25 shows another embodiment of the present invention.Go out as shown, seat element 300 engages with guard block 350,352 and forms compact equipment.Demonstrate the adhesive linkage 310 that is used for seat element 300 is bonded on the patient skin and be connected seat element 300.

Figure 26 shows the profile of embodiment shown in Figure 25.Seat element 300 comprises that a plurality of protruding 320, described protruding 320 have basal surface 322, and these basal surfaces 322 form the basal surface 324 of seat element 300 together, shown in Figure 26 and 28.Inlet port 328 can be formed in the seat element 300, and wherein inlet port 328 links to each other with path 330, and this path 330 flows with the intubate 304 of extending from seat element 300 and is connected.Guard block 352 can be removed and can be with adapter, and adapter 450,550,650 for example as described below is inserted in the conveying that same position is used for the treatment of material.Adhesive linkage 310 be bonded on the basal surface 322 of seat element 300 and the material of its formation for being inserted into the needle pierces of device (not shown), extend through intubate 304.Selectively, adhesive linkage 310 can comprise opening, and intubate 304 can be stretched out by this opening.

Figure 27 shows the exploded view of embodiment shown in Figure 25.Go out as shown, guard block 352 comprises lead arm 306 and lock arm 307, is used for engaging of guard block 352 and seat element 300.Lock arm 307 can engage with seat element 300 by the respective openings 314 in the seat element 200 described in top Fig. 5 and 6.

Figure 28 shows the exploded bottom view of embodiment shown in Figure 25.Show the projection 320 that on seat element 300, has basal surface 322.Seat element 300 further comprises outer surface 332, and its periphery around seat element 300 is extended, and adhesive linkage 310 also can be bonded on this outer surface 332 except can being bonded on surperficial 322.Shown in Figure 25-28, the general shape of embodiment is a cylindrical shape, has adhesive linkage 310, seat element 300 and guard block 350,352, and their shape is made into can connect the equipment that together forms compactness.Those skilled in the art will appreciate that alternate shape is possible, including, but not limited to ellipse, rectangle and square, preferably the assembly of embodiment can form compact equipment.

Figure 29 A and 29B show the alternate embodiments of catheterization equipment 401.Catheterization equipment 401 comprises housing 402, thin film 403 and opening 405,407.Preferably, housing 402 is roughly cylindrical shape, though other shape also can.In the present embodiment, cylindrical shape comprises radially extends projection 413 (or flanges), limits opening 405 and 407, and is positioned in seat element for example in the seat element shown in Figure 30 A 400 time when it, can be used as guiding piece.As shown in the profile of Figure 29 B, thin film 403 limits cavity 406 in housing 402 housings 402, and this cavity 406 is positioned at housing 402 and is used for receiving puncture component from adapter (below be described).Intubate 404 is stretched out from housing 402 below cavity 406, shown in Figure 29 B.In this embodiment, housing 402 rotatably is attached on the seat element 400, and as shown in figure 30, therefore rotatable connection can make housing 402 rotation in seat element 400 after intubate 404 is inserted in the patient skin, and not mobile intubate 404 makes patient's pain minimization thus.Selectively, seat element 400 can turn to desired angle with respect to intubate 404, uses the inserter 50 such inserters that resemble shown in Fig. 4 to insert intubate 404 then.Shown in Figure 29 A, end portion 412 can be substantially circle so that be provided at rotation in the seat element 400.Yet to those skilled in the art, end portion 412 can be the arbitrary dimension and the shape that can move in seat element 400.

In Figure 30 A and B, can see that the intubate 404 of catheterization equipment 401 is connected on seat element 400 and the inserter 450.In this embodiment, seat element 400 comprises link 446, and this link 446 is suitable for receiving the end portion 412 of housing 402.The shape and size of link 446 and end portion 412 can be made and be convenient to housing 402 with respect to seat element 400 rotations.Equipment 401 further comprises adhesive linkage 410, is used for seat element 400 is bonded to patient's skin.Demonstrating adhesive linkage 410 is connected on the seat element 400, and adhesive linkage 410 can comprise cut-out 448, its be when rotation in the link 446 of end portion 412 at seat element 400 of housing 402 be that intubate 404 is used when changing intubate 404 with respect to the angle of skin.

Adapter 450 is connected on the catheterization equipment housing 402 by the opening in the housing 402 405,407 and (is also illustrated and illustrate below with reference to Figure 31 A).Adapter 450 can further comprise pipe fitting 452, is used for therapeutant is transported to intubate 404 so that carry to the patient.Adapter 450 can comprise button 454, is used for adapter 450 and discharges from housing 402.Selectively, adapter 450 can be used from any method that housing 402 discharges, include, but are not limited to push external part 456 on each sidepiece of adapter 450 to discharge gripper arms 458 (shown in Figure 31 A).

Adapter 450 before Figure 31 A shows and is connected with housing 402.Adapter 450 can comprise lock arm 458 and guiding device 470, and they are similar with guiding device to the lock arm of the used guard block of above-mentioned catheterization equipment 1.Lock arm 458 makes adapter 450 can be inserted in the opening 405 in the housing 402 and be locked in the appropriate location removedly to be used for the delivering therapeutic material.Adapter 450 also can comprise lancet and means 480, and this lancet and means 480 is connected to intubate 404 with adapter 450.Thereby lancet and means 480 can pass thin film 403 and be inserted into and enter in the intubate 404 or enter in the chamber 406 to flow with intubate 404 and are communicated with.Lancet and means 480 is suitable for rupturing in the precalculated position.This just makes adapter 450 to be used as inserter so that insert the intubate 404 of catheterization equipment 401.Lancet and means 480 can rupture in desired place then, thereby uses adapter 450 in a conventional manner.Lancet and means 480 extends through thin film and can pierce through thin film, but might not puncture thin film.For example, lancet and means can insert by preformed hole on the thin film.Term lancet and means used herein can comprise intubate, comprises rigid cannula or syringe needle, semi-rigid intubate, or soft intubate or be fit to pierce through any parts of thin film.

Shown in Figure 31 A and B, the seat element 400 of this embodiment can be deflection or hinged so that the rotation of housing 402 in seat element 401.Figure 31 B shows the intubate 404 that turns to skin and deflection so that the seat element 400 of rotation.Seat element 401 can further comprise hinge 472, and described hinge 472 is connected on the link 446.Hinge 472 can be used for intubate 404 is rotated to angle towards skin from being parallel to skin.The rotation of housing 402 also can make intubate 404 be placed in the skin, simultaneous syringe needle, for example syringe needle shown in the catheterization equipment 1 51.Adapter 450 can be connected at any angle and insertion equipment 480 can be inserted into the thin film 403 from a plurality of directions.

The intubate 404 that Figure 32 A is formed on the cavity 406 in the housing 402 and stretches out from cavity 406.Figure 32 B has shown from the part of the housing 402 of seat element 400 excisions.Show link 446 and be lobed periphery 474 of circular structure and central pit 476, this central authorities' pit 476 is suitable for receiving the end portion 412 of housing 402.A part that demonstrates seat element 400 is stretched out from link 446.Figure 32 C shows from being parallel to the intubate 404 of skin direction rotation.Figure 32 D shows the vertical view of catheterization equipment 401.

Figure 33 A-D shows catheterization equipment 401, and it has along being different from the intubate 404 that direction shown in the prior figures 30-32 is extended.Demonstrate intubate 404 and be basically perpendicular to intubate 404 extensions shown in Figure 31-32.Figure 33 B shows catheterization equipment 401 and is in intubate 404 from seat element 400 vertically extending states.Demonstrating adapter 450 is connected in the opening 405,407 that is in housing 402 on the housing 402 removedly.Opening 482 in the adhesive linkage 410 has been shown, so that intubate 404 extends through and enters in patient's the skin in Figure 33 B.Figure 33 C and D show respectively the vertical view at the catheterization equipment 401 shown in Figure 33 A and the B.

Figure 34 shows the housing 402 with opening 405,407.Demonstrate the central authorities that thin film 403 is in housing 402 and be used to receive insertion equipment, this insertion equipment is used for by the conveying of flowing of 404 pairs of therapeutants of intubate.Demonstrate end portion 412 and have and be roughly orthogonal shape, be used for matching with the link 446 of the similar shape of the seat element 400 shown in Figure 34 B.As mentioned above, housing 402 is rotatable in seat element 400.

Figure 35 shows the cavity 406 that is formed on housing 402 inside.Thin film 403 can cover the part of cavity 406.Cavity 406 in the top section 484 of intubate 404 and the housing 402 is connected.Cavity 406 can supply the usefulness of lancet and means from any receive direction insertion thin film 403 of adapter, and makes intubate 404 be communicated with the conveying that is used for the treatment of material with the adapter fluid.In this embodiment, demonstrating intubate 404 vertically stretches out from housing 402 with respect to the plane 418 of seat element 400.Showing paired opening 486 is positioned at and is used for receiving connector or guard block on two different directions on the housing 402.Seat element 400 also comprises substantially and is the link 446 of square shape, is used to receive the end portion 412 of housing 402.Adhesive linkage 410 can be bonded on patient's the skin.

Figure 36 A-E demonstrates catheterization equipment 401 from different perspectives.Figure 36 A shows the vertical view of catheterization equipment 401, and wherein adapter 450 is connected on the housing 402.Demonstrating intubate 404 extends along the direction that is basically parallel to seat element 400.Pipe fitting 452 is used to be connected to the armarium (not shown) with the delivering therapeutic material from adapter 450 extensions.Figure 36 B shows the catheterization equipment 401 from Figure 36 A, and wherein adapter 450 is removed.Figure 36 C shows the perspective view of the catheterization equipment 401 of Figure 36 A.Figure 36 D shows the rear view of catheterization equipment 401, and wherein adapter 450 is connected on the housing 402.

Figure 37 A-C shows catheterization equipment 401, and wherein intubate 404 is extended along the direction on the plane 418 that is basically perpendicular to seat element 400.Figure 37 A demonstrates adapter 450 and is connected in the cover in the opening 484 in the housing 402, wherein connects the plane that is parallel to seat element 400.Show into and second in the opening 488 is enclosed within the second party that adapter 450 can be inserted into is open upwards, wherein connect the plane 418 that is substantially perpendicular to seat element 400.Figure 37 B shows the side perspective view of catheterization equipment 401, and intubate 404 is extended below seat element 400.Figure 37 C shows the vertical view of equipment shown in Figure 37 A.

Figure 38 A shows the catheterization equipment among Figure 37 A, and its middle shell 402 is repositioned in the seat element 400, so intubate 404 is basically parallel to plane 418 extensions of seat element 400.Demonstrate adapter 450 and be connected to housing 402 along the direction that is parallel to the plane 418 of seat element 400.Figure 38 B is the vertical view of catheterization equipment 401 shown in Figure 38 A, can see at this, is connected from the lead arm 470 and the lock arm 458 of adapter 450 and forms removable being connected on the housing 402.

Figure 39 shows the catheterization equipment 501 that is connected on the inserter 550.Showing catheterization equipment 501 is removed from seat element so that demonstrate being connected of guiding device 505 of inserter 560 and catheterization equipment 501.

Shown in Figure 40 A and B, can catheterization equipment 501 be connected on the adapter 550 from the different height and distance place of patient skin, thereby intubate 504 can extend into the different depth in the patient skin.In Figure 40 A and Figure 41 A positioning element 507 has been shown, it is positioned at catheterization equipment 501 belows.Positioning element 507 can be positioned between base member 500 (shown in Figure 43) and the catheterization equipment 501, is used for changing the height and distance that catheterization equipment 501 is inserted into skin.Positioning element 507 can make catheterization equipment 501 be positioned in the adapter 550 more eminence in Figure 40 A, when compare with catheterization equipment residing position in adapter 550 among Figure 40 B that does not have positioning element (also seeing Figure 41 A and 41B).Use a plurality of guiding devices also catheterization equipment can be positioned at a plurality of height with respect to seat element.Catheterization equipment can make a catheterization equipment and seat element one be used from insertion depth more than one with respect to a plurality of height of seat element, makes infusion set be suitable for different separately patients and also therefore makes infusion set can be used for child and adult.Catheterization equipment 501 also comprises thin film 503, and this thin film 503 is suitable for receiving lancet and means 580 from adapter 550, intubate for example, thus adapter 550 is fluidly coupled to the conveying that intubate 504 is used for the treatment of material.It should be appreciated by those skilled in the art that intubate can be inflexible, such as, but be not limited to syringe needle, semirigid or soft.

Figure 41 A and B show the partial view of embodiment shown in Figure 40 A and the B.Figure 41 A shows permission connects catheterization equipment 501 and adapter 550 from two different directions embodiment.As shown in, thin film 503 is a monofilm, is installed on the housing 502.As described below, a plurality of thin film 503 also are possible.The lancet and means 580 that is shown as intubate can and pierce through thin film 503 and depend on that lancet and means 580 is received the direction the catheterization equipment 501 from adapter 550 extensions, lancet and means 580 can stop in one in two cavitys 512, and described two cavitys 512 are formed in the catheterization equipment 501.Two cavitys 512 can be communicated with by the path 514 mutual fluids that are formed in the catheterization equipment 501.Preferably, path 514 is arranged on housing 502 inside.This embodiment can make lancet and means 580 be communicated with intubate 504 fluids, no matter insertion equipment is inserted into the direction of passing thin film 503.Shown in Figure 41 A, lancet and means 580 is basic vertical with the intubate 504 of catheterization equipment 501, and cavity 512, and lancet and means 580 inserts in this cavity 512 and therein and stops, the communication paths 514 that flows and the cavity 516 that is connected with intubate 504.One skilled in the art would recognize that lancet and means 580 also can be inserted into the thin film 503 at the top from the direction that is basically parallel to intubate 504 from catheterization equipment 501.Lancet and means 580 also can insert and penetrate thin film 503 and lancet and means 580 can stop in intubate 504, and like this, lancet and means 580 can be directly flows with intubate 504 and is communicated with and do not link to each other by cavity 512 or path 514.

Figure 41 B shows catheterization equipment 501, and it can be connected to lancet and means 580 from both direction, and wherein lancet and means 580 any one direction from two is passed thin film 503 and is connected to single chamber 522.When lancet and means 580 passed thin film 503 and is inserted on the direction perpendicular to intubate 504 directions, insertion equipment can enter chamber 522 from the hole 524 the wall 523 of chamber 522.Figure 41 A also shows catheterization equipment 501 with B and is connected in the adapter 550 with different height.

Figure 42 A and B show the side view of catheterization equipment 501, and catheterization equipment 501 is connected in the adapter 550 with different height.

Figure 43 shows adapter 550, and it links to each other with catheterization equipment 501 and catheterization equipment 501 can be installed in the seat element 500.Go out as shown, adapter 550 connects along the direction that is parallel to seat element 500 principal planes.Adapter 550 comprises lancet and means 580, demonstrates lancet and means 580 and directly links to each other with intubate 504 by thin film 503.

Figure 44 demonstrates catheterization equipment 501 and is connected on the adapter 550 and is installed in the seat element 500.Intubate 504 is extended along the direction on the plane 518 that is parallel to seat element 500, perpendicular to the direction shown in Figure 42 A and the B.Adapter 550 comprises lead arm 506 and lock arm 507.As mentioned above, lead arm helps catheterization equipment 501 to be positioned in the seat element 500, and lock arm 507 locks together adapter 550 and seat element 500 removedly.Demonstrating lock arm 507 stretches into and locks the part of seat element 500 and enter in the opening 511 on the seat element 500.The sidepiece 513 of lock arm 507 comprises ridge 517 helping patient's lock arm 507 of holding with a firm grip, thereby and adapter 550 and seat element 500 is slided promotion lock connector 550 and seat element 500 removedly together.Gripper arms 507 also can be a deflection, so the patient can inwardly push so that discharge lock arm from seat element 500 on lock arm 507.Thin film 503 keeps exposed state at the top of catheterization equipment 501.

Figure 45 shows catheterization equipment 501 together with adapter 550 and pipe fitting 552 and seat element 500.Also show adhesive linkage 510 and have the cut-out of establishing for intubate 504 515.

Figure 46 shows catheterization equipment 501, and it is installed on the seat element 500, and intubate 504 is extended along the direction that is parallel to seat element 500 principal planes.Inserter 560 can be connected on seat element 500 and the catheterization equipment 501.Syringe needle 561 stretches out the thin film 503 that passes catheterization equipment and passes intubate 504 from inserter 560.Figure 47 shows at the catheterization equipment shown in Figure 46 501 and can rotate on perpendicular to the direction shown in Figure 46, and its be installed in seat element 500 identical shown in Figure 46 on.Intubate 504 is extended downwards from seat element 500.Also demonstrating inserter 560 is connected with catheterization equipment 501 with seat element 500 on perpendicular to the direction of direction shown in Figure 46.

Figure 48 shows inserter 560.Syringe needle 561 stretches out from inserter 560, and lead arm 563 can be stretched out the guiding device (do explanation and illustrate as top) of the catheterization equipment that is used for being slidingly connected in the both sides of syringe needle 561 so that guiding inserter 560 enters the position of catheterization equipment 501.

Figure 49 has shown the similar embodiment with embodiment shown in Figure 45, and it has seat element with angle 600.Seat element 600 with angle can clearerly in side view shown in Figure 51 be seen, wherein demonstrates adapter 650 and is inserted in the seat element 600 with principal plane 618 certain angles with respect to seat element.Can on comprising several directions shown in Figure 49, catheterization equipment 601 be installed in the seat element 600, make intubate 604 extend from the direction that seat element 600 edges are basically parallel to the principal plane 618 of seat element 600.Adapter 650 can be connected on seat element 600 and the catheterization equipment 601.Adapter 650 can comprise lancet and means 680, and this lancet and means 680 inserts the thin film 603 that passes catheterization equipment 601 so that be communicated with the skin that is used for therapeutant is transported to the patient at pipe fitting 652 to setting up fluid between the intubate 604.Adapter 650 also can comprise lock arm 607, and described lock arm 607 extends through opens 611 so that adapter 650 is locked onto on the seat element 600 removedly in the adapter 650.Also show adhesive linkage 610, it is connected on the seat element 600 and adhesive linkage 610 can be included as intubate 604 and the cut-out 615 established.Figure 50 shows the vertical view of embodiment shown in Figure 49.

Figure 52 show have a seat element with angle 600 broadcast tube apparatus 601.As mentioned above, adapter 650 can be connected with seat element 600.Adapter 650 comprises that further lead arm is positioned in the seat element 600 (not shown, as described in the embodiment among top Fig. 6) to help catheterization equipment 601.Lock arm 607 by the opening 611 in the seat element 600 with engage removedly at seat element 600.Demonstrate the part that lock arm 607 stretched into and locked removedly seat element 600, enter into the opening 611 of seat element 600.The sidepiece 613 of lock arm 607 can comprise that ridge 617 is to help patient hold with a firm grip lock arm and lock connector 650 and seat element 600 removedly.Gripper arms 607 also can be a deflection, so the patient can inwardly push on lock arm 507 so that discharge lock arm 607 from seat element 600.Figure 53-57 shows the perspective view of catheterization equipment shown in Figure 52 601.

Figure 58-65 shows another preferred embodiment of the present invention.In Figure 58 and 59, catheterization equipment 701 is made into cube and is positioned in the seat element 700, so the intubate 704 of catheterization equipment 701 is basically perpendicular to the first type surface 705 of seat element 700.As mentioned above, the catheterization equipment 701 of other shape also is possible.Catheterization equipment 701 can receive the insertion syringe needle (for example, in front described in Fig. 4 and illustrate) of inserter and the adapter 750 with intubate 751 from being basically parallel to intubate 704 directions.Catheterization equipment 701 can comprise at least one thin film 703, inserts syringe needle or lancet and means 751 and inserts by this thin film 703.Figure 58 and 59 shows the catheterization equipment 701 with two thin film 703, however, it will be understood by those skilled in the art that more thin film 703 is possible.Guard block or inserter also can be used for catheterization equipment 701 and seat element 700 substitutes adapter 750, as mentioned above.

In addition, Figure 58 and 59 illustrates, and adapter 750 can be connected with seat element 700 from the direction that is basically perpendicular to intubate 704, and lancet and means 751 can pierce through thin film 703 from the direction perpendicular to the adapter shown in Figure 58 750.The make of catheterization equipment 701 is that when not considering to receive the direction reception intubate 704 of lancet and means 751, intubate 704 is communicated with lancet and means 751 fluids.In Figure 58 and 59 illustrated embodiments, catheterization equipment comprises cavity 706, and its cavity 6 to aforementioned catheterization equipment 1 is similar.Selectively, catheterization equipment 701 can not comprise cavity 706, and wherein lancet and means 751 flows with intubate 704 and is communicated with, and is similar under the situation that does not have cavity 706 and receives lancet and means, is similar to the equipment described in top Figure 41 B.

But Figure 58 and 59 also shows the selection mechanism that is used for removing lock connector 750 and seat element 700.Adapter 750 comprises lock arm 707, is used for seat element 700 is removably locked onto adapter 750.Lock arm 707 further comprises trough of belt mouth projection 720, is used for being bonded on seat element 700 with angle protruding 722.The trough of belt mouth of adapter 750 projection 720 slidably engages with angle protruding 722 of seat element 700.Thereby projection 720 is interlocked with projection 722 and projection 720 connects in the gap of seat element 700 seat element 700 is locked onto adapter 750 releasedly.Seat element 700 can be discharged from adapter 750 by on projection 720, pushing.Adapter 750 can also comprise lead arm 706, so that engage the guiding device 705 of catheterization equipment 701 slidably.Certainly, can use alternate locking means to engage seat element 700 and adapter 751 releasedly.

Figure 58-60 shows intubate 704, and its first type surface 705 that is basically perpendicular to seat element 700 extends, so intubate 704 first type surface 705 that is basically perpendicular to seat element 700 penetrates patient's skin.Seat element 700 comprises opening 709, and the intubate 704 of catheterization equipment 701 can be extended by this opening 709.

Figure 61 shows intubate 704, and its first type surface 705 that is basically parallel to seat element 700 passes opening 709 and extends in seat element 700.Figure 62 and 63 show with catheterization equipment 701 before seat element 700 is connected, at this, intubate 704 will extend through opening 709, be basically parallel to the first type surface 705 of seat element 700.

Figure 64 shows the example of the inner portion 713 of catheterization equipment 701.In this embodiment, lancet and means 751 will directly insert in the passage 715, and be not used in the cavity of aforesaid mobile connection lancet and means 751 and intubate 704.Intubate adapter 751 can from shown in any direction two pierce through thin film 703 and directly thereby admission passages 715 and intubate 704 flow and be communicated with.

Though describe the present invention in conjunction with the preferred embodiments of the present invention at this, but it should be appreciated by those skilled in the art, do not specify in addition additional, revise, substitute and delete be can make and do not break away from aim of the present invention and the scope that claims limit.Therefore can be understood as with aforesaid detailed description as illustrating rather than limiting, following claim comprises all equivalents, is to limit aim of the present invention and scope.

Figure 65 shows the section of spheroid, and it is limited by two planes, and different sections is cut into spheroid in described two planes, and wherein said two planes have intersecting lens in spheroid.The shape of this section is of great use as the shape of catheterization equipment housing.As substituting of spheroid section, can use the ellipsoidal section that limits with the same manner, the i.e. ellipsoidal section that limits by two planes, different sections is cut into ellipsoid in described two planes, and wherein said two planes have intersecting lens in ellipsoid.

Claims

1. catheterization equipment (1,201,401 that is used for infusion set, 501,601,701), be used to be installed in seat element (100,200,300,400,500,600,700) in, described catheterization equipment comprises housing (2,402,502) and at least one thin film (3,403,503,603,703), described housing and described at least one thin film limit at least one together and are suitable for receiving connector (450,550,650,750) lancet and means (580,680) cavity (6,406,706), described catheterization equipment (1,201,401,501,601,701) further comprise intubate (4,304,404,504,604,704), this intubate is installed in described housing (2,402,502) in and with described at least one cavity (6,406,706) fluid is communicated with, and wherein said catheterization equipment can be from the described lancet and means (580,680) of first receive direction (18) receiving connector, and in addition can be from being different from second receive direction (20) receiving connector (450,550,650 of described first receive direction (18), 750) described lancet and means (580,680), thereby at the lancet and means (580 of adapter, 680) and described at least one cavity (6,402,502) provide fluid to be communicated with between, described catheterization equipment has and is used for catheterization equipment (1,201,401,501,601,701) be attached to the related device (101 of seat element, 210) device on (5), and described catheterization equipment is characterised in that described housing (2,402,502) geometry that has makes intubate (4,304,404,504,604,704) can along more than one direction (18,20) from seat element (100,200,300,400,500,600,700) stretch out.

2. catheterization equipment as claimed in claim 1 is characterized in that described catheterization equipment (1,201,401,501,601,701) comprises the thin film (3,403,503,603,703) that is used for each receive direction (18,20).

3. catheterization equipment as claimed in claim 1 or 2 is characterized in that described catheterization equipment comprises two thin film (3,403,503,603,703).

4. catheterization equipment as claimed in claim 1 is characterized in that the angle between first receive direction (18) and second receive direction (20) is at least 45 °.

5. catheterization equipment as claimed in claim 1 is characterized in that catheterization equipment (1,201,401,501,601,701) is suitable for receiving intubate (4,304,404,504,604,704) from other direction.

6. catheterization equipment as claimed in claim 5 is characterized in that the angle between described first receive direction (18) and described other direction (20) is 5 °-175 °.

7. catheterization equipment as claimed in claim 1 is characterized in that described thin film (3,403,503,603,703) is self-packing.

8. catheterization equipment as claimed in claim 7 is characterized in that described thin film (3,403,503,603,703) made by silicones.

9. catheterization equipment as claimed in claim 1 is characterized in that the housing (2,402,502) of described catheterization equipment (1,201,401,501,601,701) comprises guiding device (5,505).

10. catheterization equipment as claimed in claim 1 is characterized in that the housing (2,402,502) of described catheterization equipment (1,201,401,501,601,701) comprises locking device (14).

11. catheterization equipment as claimed in claim 10 is characterized in that the locking device (4) of described catheterization equipment (1,201,401,501,601,701) further comprises releasing device, is used to throw off locking device (14).

12. catheterization equipment as claimed in claim 9 is characterized in that guiding device (5,505) guide cannula equipment (1,201,401,501,601,701) with seat element (100,200,300,400,500,600,700) assembling, guide cannula equipment (1,201,401,501,601,701) with adapter (450,550,650,750) combination, and/or guide cannula equipment (1,201,401,501,601,701) with the combination of inserter (50,560).

13. catheterization equipment as claimed in claim 1 is characterized in that the housing (2,402,502) of described catheterization equipment (1,201,401,501,601,701) comprises a plurality of pits.

14. catheterization equipment as claimed in claim 1 is characterized in that described catheterization equipment (1,201,401,501,601,701) has drum.

15. catheterization equipment as claimed in claim 1 is characterized in that described catheterization equipment (1,201,401,501,601,701) comprises a cavity (6), this cavity is by membrane sealed.

16. seat element (100,200,300,400,500,600,700) catheterization equipment (1,201 that, is used for infusion set, 401,501,601,701) be installed in the described seat element, described catheterization equipment comprises housing (2,402,502) and at least one thin film (3,403,503,603,703), described housing and described at least one thin film limit at least one together and are suitable for receiving connector (450,550,650,750) lancet and means (580,680) cavity (6,406,706), described catheterization equipment (1,201,401,501,601,701) further comprise intubate (4,304,404,504,604,704), this intubate is installed in described housing (2,402,502) in and with described at least one cavity (6,406,706) fluid is communicated with, and wherein said catheterization equipment can be from the described lancet and means (580,680) of first receive direction (18) receiving connector, and in addition can be from being different from second receive direction (20) receiving connector (450,550,650 of described first receive direction (18), 750) described lancet and means (580,680), thereby at the lancet and means (580 of adapter, 680) and described at least one cavity (6,402,502) provide fluid to be communicated with between, described catheterization equipment has and is used for catheterization equipment (1,201,401,501,601,701) be attached to the related device (101 of seat element, 210) device on (5), and described catheterization equipment is characterised in that described housing (2,402,502) geometry that has makes intubate (4,304,404,504,604,704) can along more than one direction (18,20) from seat element (100,200,300,400,500,600,700) stretch out.

17. seat element as claimed in claim 16 is characterized in that described catheterization equipment (1,201,401,501,601,701) can be attached on the seat element (100,200,300,400,500,600,700) with differentiated levels.

18. seat element as claimed in claim 16 is characterized in that seat element (100,200,300,400,500,600,700) have catheterization equipment (1,201,401,501,601,701) on more than one direction, be attached to seat element (100,200,300,400,500,600,700) device on, described catheterization equipment has catheterization equipment (1,201,401,501,601,701) central axis.

19. as each the described seat element among the claim 16-18, it is characterized in that described seat element comprises guiding device (101,201), described guiding device is suitable for engaging with the guiding device (5) of catheterization equipment (1,201,401,501,601,701).

20., it is characterized in that described seat element comprises locking device as each the described seat element among the claim 16-18.

21. seat element as claimed in claim 20 is characterized in that described locking device is used for catheterization equipment (1,201,401,501,601,701) is locked onto on the seat element (100,200,300,400,500,600,700).

22. seat element as claimed in claim 20 is characterized in that described locking device is used for a connector is locked onto on the seat element (100,200,300,400,500,600,700).

23., it is characterized in that described catheterization equipment (1,201,401,501,601,701) can be with respect to the remainder rotation of seat element (100,200,300,400,500,600,700) as each the described seat element among the claim 16-18.

24. seat element as claimed in claim 23 is characterized in that described catheterization equipment (1,201,401,501,601,701) is attached on the seat element (100,200,300,400,500,600,700) by hinge (472).

25. one kind includes seat element (100,200,300,400,500,600,700) and adapter (450,550,650,750) infusion set, this seat element comprise as each describedly is used to insert the intravital catheterization equipment (1,201 of patient among the claim 1-15,401,501,601,701), described adapter (450,550,650,750) by conduit with seat element (100,200,300,400,500,600,700) link together described adapter (450 with armarium, 550,650,750) comprise adapter (450,550,650,750) lancet and means (580,680,751), this lancet and means is communicated with described catheter fluid; Seat element (100,200,300,400,500,600,700) comprises the first cover guiding device and the first cover locking device, is used for adapter is locked onto on the seat element (100,200,300,400,500,600,700); Described adapter (450,550,650,750) but comprise is suitable for the second cover guiding device that connects with the first cover guiding device and is suitable for locking device with second cover of delivery mode and the first cover locking means for engaging.