CN100527947C - Computer automatic analysis processing system for animal shuttle box - Google Patents
Computer automatic analysis processing system for animal shuttle box Download PDFInfo
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- CN100527947C CN100527947C CNB2007100049925A CN200710004992A CN100527947C CN 100527947 C CN100527947 C CN 100527947C CN B2007100049925 A CNB2007100049925 A CN B2007100049925A CN 200710004992 A CN200710004992 A CN 200710004992A CN 100527947 C CN100527947 C CN 100527947C
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- 238000000034 method Methods 0.000 claims abstract description 11
- 230000000638 stimulation Effects 0.000 claims abstract description 9
- 238000005286 illumination Methods 0.000 claims description 12
- 238000005424 photoluminescence Methods 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 3
- 229910052710 silicon Inorganic materials 0.000 claims description 2
- 239000010703 silicon Substances 0.000 claims description 2
- 238000002474 experimental method Methods 0.000 abstract description 12
- 238000012360 testing method Methods 0.000 description 2
- 229920005479 Lucite® Polymers 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 208000018459 dissociative disease Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
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- 230000011514 reflex Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012549 training Methods 0.000 description 1
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Abstract
The invention belongs to an animal experiment device, and particularly relates to shuttle experiment equipment controlled by a computer. The animal shuttle box computer automatic analysis processing system comprises: a shuttle box body [11], a background light irradiation device [12], a stimulation light irradiation device [13], an electrical stimulation device [14] and an image pickup device [15 ]; a main control computer [21], a video card [22], an interface circuit card [23], and shuttle experiment software [24 ]; the shuttle experiment software [24] sets shuttle experiment programs and parameters, controls the main control computer [21] to send background light, laser and electrical stimulation instructions, receives and processes video signals, and counts, records and displays experiment data. The invention can set various experimental modes, set the optimal experimental conditions according to the animal characteristics, automatically record the animal track with time coordinates, automatically give experimental data and statistic analysis, avoid the interference of external light sources to the experiment and ensure the repeatability of the experiment.
Description
Technical field
The invention belongs to a kind of animal experiment device capable, particularly a kind of experimental facilities that shuttles back and forth that computerizeds control.
Background technology
Shuttle back and forth and be meant if animal does not react to a certain signal specific (as light, sound) at the appointed time, then give punitive and stimulate (electro photoluminescence commonly used), make animal shuttle to the offside place of safety (passive conditioned reflex), then can form initiatively fugue reaction (active condition reflection) within a certain period of time after the repetition training.Animal not only will learn to avoid punitive to stimulate in official hour, also will learn and remember certain signal (as light, sound) and the relation that punitive stimulates, and could form the active condition reflection.Therefore, the complicated learning and memory forming process of the most approaching reflection animal of shuttling back and forth is one of best behaviouristics method of testing of research meiofauna learning and memory behavior.
The at present domestic and international employed experimental facilities that shuttles back and forth, the shuttle box system that develops as Bioseb company is made up of shuttle box testing cassete, stimulator and computer system, and adopts pressure sensor detects the positional information in shuttle box of animal.Though this cover system has adopted calculator, stimulator is by manual operation start; Once can only observe a sample; Data message only can obtain the passive total degree that shuttles back and forth, total degree, the latent period of carrying out camera bellows, the intertrial interval number of times etc. that shuttles back and forth that shuttles back and forth initiatively.Equally also there is this problem in the shuttle box of selling as Columbus company in addition, and the shuttle box system of the said firm is positioned in shuttle box rat by photoelectric sensor.Though whole box body adopts the lucite system to become, outward appearance is exquisite, does not have much othernesses with Bioseb company on practical operation and the information content obtained.Existing shuttle box has a common defective, and that is limited by external condition exactly, and the repeatability of test is poor.
Summary of the invention
The objective of the invention is: a kind of automaticity height is provided, obtain contain much information, science, standard and sensitive computer automatic analysis process system of animal shuttle box.
Technical scheme of the present invention is: a kind of computer automatic analysis process system of animal shuttle box, and it comprises: shuttle box and computer system;
Described shuttle box comprises: the casing that shuttles back and forth, background illumination injection device, thorn laser irradiation device, electrical stimulation device, camera head;
The described casing that shuttles back and forth [11] adopts light-proof material to make;
Described background illumination injection device uses a plurality of infrared light pipes as light source, and described a plurality of infrared light pipes are parallel to be distributed in both sides in the described casing that shuttles back and forth, and controls it by the bias light control circuit and ignite and illumination;
Described thorn laser irradiation device uses the blue light-emitting diode array as light source, is arranged in the described casing that shuttles back and forth, and controls it by the thorn laser control circuit and ignite and illumination;
The egersimeter of described electrical stimulation device is arranged in the described casing that shuttles back and forth, and controls the electric pulse that it produces adjustable constant intensity or two kinds of patterns of peak value random strength by the electro photoluminescence control circuit;
Described camera head is arranged at the described casing inner top that shuttles back and forth;
Described computer system comprises: main control computer, and video card, the interface circuit card, experiment software shuttles back and forth;
Described video card is accepted the vision signal of described camera head, passes to described main control computer and handles;
Described interface circuit clamping is instructed by described main control computer, controls described bias light control circuit, described thorn laser control circuit, described electro photoluminescence control circuit, described camera head work;
The described experiment software setting of shuttling back and forth shuttle back and forth experimental arrangement and parameter are controlled described main control computer and are sent bias light, thorn laser, electro photoluminescence instruction, receive and handle vision signal, statistics, record and show experimental data.
Use the present invention and can set the kinds of experiments mode,, set best experiment condition according to animalism, animal track that can the free coordinate of record chart, automatically provide experimental data and statistical analysis, and can avoid the interference of external light source, guarantee the repeatability of experiment experiment.
Description of drawings
Accompanying drawing 1 is the structure chart of the casing that shuttles back and forth among the present invention;
Accompanying drawing 2 is the theory diagram of computer system among the present invention and other circuit.
Embodiment
Embodiment 1: referring to accompanying drawing 1,2, and a kind of computer automatic analysis process system of animal shuttle box, it comprises: shuttle box 1 and computer system 2;
Described shuttle box 1 comprises: the casing 11 that shuttles back and forth, background illumination injection device 12, thorn laser irradiation device 13, electrical stimulation device 14, camera head 15;
The described casing 11 that shuttles back and forth adopts light-proof material to make;
Described background illumination injection device 12 uses a plurality of infrared light pipe 121 as light source, and described a plurality of infrared light pipe 121 is parallel to be distributed in both sides in the described casing 11 that shuttles back and forth, and it ignites and illumination by 122 controls of bias light control circuit;
Described thorn laser irradiation device 13 uses blue light-emitting diode array 131 as light source, be arranged in the described casing 11 that shuttles back and forth, and it ignites and illumination by 132 controls of thorn laser control circuit;
The egersimeter 141 of described electrical stimulation device 14 is arranged in the described casing 11 that shuttles back and forth, and it produces the electric pulse of adjustable constant intensity or two kinds of patterns of peak value random strength by 142 controls of electro photoluminescence control circuit;
Described camera head 15 is arranged at described casing 11 inner tops that shuttle back and forth;
Described computer system 2 comprises: main control computer 21, and video card 22, interface circuit card 23, experiment software 24 shuttles back and forth;
Described video card 22 is accepted the vision signal of described camera head 15, passes to described main control computer 21 and handles;
Described interface circuit card 23 is accepted described main control computer 21 instructions, controls described bias light control circuit 122, described thorn laser control circuit 132, described electro photoluminescence control circuit 142,15 work of described camera head;
Described experiment software 24 setting of shuttling back and forth shuttle back and forth experimental arrangement and parameter are controlled described main control computer 21 and are sent bias light, thorn laser, electro photoluminescence instruction, receive and handle vision signal, statistics, record and show experimental data.
Embodiment 2; Referring to accompanying drawing 1,2, as embodiment 1 described computer automatic analysis process system of animal shuttle box, 2 covers or the many cover of described shuttle box 1 for using simultaneously carries out 2 the road or the multichannel experiment of shuttling back and forth automatically; Described shuttle box 1 bottom can be extracted out, so that cleaning zoopery legacy; Described computer system 2 also comprises printer 25, so that experimental data output.
Embodiment 3: as embodiment 1 or 2 described computer automatic analysis process system of animal shuttle box, described electro photoluminescence control circuit 142 uses controllable silicon to produce the electric pulse of adjustable constant intensity or two kinds of patterns of peak value random strength.
Claims (3)
1. computer automatic analysis process system of animal shuttle box, it is characterized in that: it comprises: shuttle box [1] and computer system [2];
Described shuttle box [1] comprising: the casing that shuttles back and forth [11], background illumination injection device [12], thorn laser irradiation device [13], electrical stimulation device [14], camera head [15];
The described casing that shuttles back and forth [11] adopts light-proof material to make;
Described background illumination injection device [12] uses a plurality of infrared light pipes [121] as light source, the parallel interior both sides of the described casing that shuttles back and forth [11] that are distributed in of described a plurality of infrared light pipes [121], and control it by bias light control circuit [122] and ignite and illumination;
Described thorn laser irradiation device [13] uses blue light-emitting diode array [131] as light source, is arranged in the described casing that shuttles back and forth [11], and controls it by thorn laser control circuit [132] and ignite and illumination;
The egersimeter [141] of described electrical stimulation device [14] is arranged in the described casing that shuttles back and forth [11], and controls the electric pulse that it produces adjustable constant intensity or two kinds of patterns of peak value random strength by electro photoluminescence control circuit [142];
Described camera head [15] is arranged at the described casing that shuttles back and forth [11] inner top;
Described computer system [2] comprising: main control computer [21], video card [22], interface circuit card [23], the experiment software that shuttles back and forth [24];
Described video card [22] is accepted the vision signal of described camera head [15], passes to described main control computer [21] and handles;
Described interface circuit card [23] is accepted described main control computer [21] instruction, controls described bias light control circuit [122], described thorn laser control circuit [132], described electro photoluminescence control circuit [142], described camera head [15] work;
The described experiment software that shuttles back and forth [24] is provided with shuttle back and forth experimental arrangement and parameter, controls described main control computer [21] and sends bias light, thorn laser, electro photoluminescence instruction, receives and handle vision signal, statistics, record and show experimental data.
2. computer automatic analysis process system of animal shuttle box according to claim 1 is characterized in that: 2 covers or the many cover of described shuttle box [1] for using simultaneously, and described shuttle box [1] bottom can be extracted out; Described computer system [2] also comprises printer [25].
3. computer automatic analysis process system of animal shuttle box according to claim 1 and 2 is characterized in that: described electro photoluminescence control circuit [142] uses controllable silicon to produce the electric pulse of adjustable constant intensity or two kinds of patterns of peak value random strength.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100049925A CN100527947C (en) | 2007-02-14 | 2007-02-14 | Computer automatic analysis processing system for animal shuttle box |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100049925A CN100527947C (en) | 2007-02-14 | 2007-02-14 | Computer automatic analysis processing system for animal shuttle box |
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| CN101011036A CN101011036A (en) | 2007-08-08 |
| CN100527947C true CN100527947C (en) | 2009-08-19 |
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| CNB2007100049925A Expired - Fee Related CN100527947C (en) | 2007-02-14 | 2007-02-14 | Computer automatic analysis processing system for animal shuttle box |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101238984B (en) * | 2008-01-29 | 2010-07-21 | 中国航天员科研训练中心 | Animal dark avoidance computer automatic analysis processing system |
| CN101664340B (en) * | 2009-09-18 | 2011-05-18 | 中国医学科学院药用植物研究所 | Device for testing independent activity of animals |
| CN101965819B (en) * | 2010-07-30 | 2013-06-12 | 暨南大学 | Method for testing response behaviors of animals to infrared light |
| CN102119670B (en) * | 2011-03-07 | 2012-10-03 | 沈阳医学院 | Automated mechanical arm stimulating device for animal memory training system |
| ES2395938B1 (en) | 2011-07-19 | 2013-09-18 | Universidad Pablo De Olavide | DEVICE FOR ANIMAL EXPERIMENTATION IN NEUROSCIENCE RESEARCH |
| CN102388814B (en) * | 2011-09-01 | 2014-10-08 | 上海移数信息科技有限公司 | intelligent complex shuttle control analysis system |
| CN102499109A (en) * | 2011-10-20 | 2012-06-20 | 上海移数信息科技有限公司 | High-grade intelligent scene fear analysis system |
| CN104665759A (en) * | 2015-03-26 | 2015-06-03 | 河南中医学院 | Animal visual function determinator |
| CN105145400B (en) * | 2015-04-28 | 2018-02-16 | 中国航天员科研训练中心 | The animal light and shade shuttle Behavior Test system of compatible high strong electromagnetic pulse |
| CN111642460B (en) * | 2020-06-23 | 2022-06-28 | 山西省中医药研究院（山西省中医院） | Construction method of pineal body injury rat model |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1742568A (en) * | 2005-09-30 | 2006-03-08 | 中国人民解放军第三军医大学 | Shuttle-type exercising method for animal active avoidance response |
| CN1768578A (en) * | 2005-09-09 | 2006-05-10 | 宁波市微循环与莨菪类药研究所 | Computer control system for experimental animal operant behavior research and processing method thereof |
| CN2834160Y (en) * | 2005-09-30 | 2006-11-08 | 中国人民解放军第三军医大学 | Animal positive avoidance reaction training device |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1768578A (en) * | 2005-09-09 | 2006-05-10 | 宁波市微循环与莨菪类药研究所 | Computer control system for experimental animal operant behavior research and processing method thereof |
| CN1742568A (en) * | 2005-09-30 | 2006-03-08 | 中国人民解放军第三军医大学 | Shuttle-type exercising method for animal active avoidance response |
| CN2834160Y (en) * | 2005-09-30 | 2006-11-08 | 中国人民解放军第三军医大学 | Animal positive avoidance reaction training device |
Non-Patent Citations (1)
| Title |
|---|
| 一种全程控的大鼠穿梭箱主动回避反应实验系统及其应用. 卓豫，吴宝明，王景周，周毅.重庆医学，第35卷第10期. 2006 * |
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| CN101011036A (en) | 2007-08-08 |
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Effective date of registration: 20071214 Address after: 5104 mailbox postcode of Beijing: 100094 Applicant after: Chinese Astronaut Research and training center Co-applicant after: Medical Plants Inst. Chinese Academy of Medical Sciences Co-applicant after: Beijing 3D Tuomeng Digital Images Technology Co., Ltd. Address before: 5104 mailbox postcode of Beijing: 100094 Applicant before: Chinese Astronaut Research and training center Co-applicant before: Medical Plants Inst. Chinese Academy of Medical Sciences |
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