CN100413533C - Sustained release pharmaceutical compounds to prevent abuse of controlled substances - Google Patents

Sustained release pharmaceutical compounds to prevent abuse of controlled substances Download PDF

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Publication number
CN100413533C
CN100413533C CNB038087162A CN03808716A CN100413533C CN 100413533 C CN100413533 C CN 100413533C CN B038087162 A CNB038087162 A CN B038087162A CN 03808716 A CN03808716 A CN 03808716A CN 100413533 C CN100413533 C CN 100413533C
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CN
China
Prior art keywords
hydrocodone
conjugate
aminoacid
peptide
naltrexone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB038087162A
Other languages
Chinese (zh)
Other versions
CN1720059A (en
Inventor
T·皮卡里罗
R·J·科克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shire LLC
Original Assignee
Shire LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US35836802P priority Critical
Priority to US60/358,368 priority
Priority to US60/362,082 priority
Application filed by Shire LLC filed Critical Shire LLC
Publication of CN1720059A publication Critical patent/CN1720059A/en
Application granted granted Critical
Publication of CN100413533C publication Critical patent/CN100413533C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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