CL2016000959A1 - Adenovirus oncolíticos armados con genes heterologos - Google Patents

Adenovirus oncolíticos armados con genes heterologos

Info

Publication number
CL2016000959A1
CL2016000959A1 CL2016000959A CL2016000959A CL2016000959A1 CL 2016000959 A1 CL2016000959 A1 CL 2016000959A1 CL 2016000959 A CL2016000959 A CL 2016000959A CL 2016000959 A CL2016000959 A CL 2016000959A CL 2016000959 A1 CL2016000959 A1 CL 2016000959A1
Authority
CL
Chile
Prior art keywords
heterologous genes
oncolytic adenoviruses
armed
adenoviruses armed
oncolytic
Prior art date
Application number
CL2016000959A
Other languages
English (en)
Inventor
Brian Robert Champion
Alice Claire Noel Brown
Kerry David Fisher
Tamara Nicolson
Original Assignee
Psioxus Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1318880.0A external-priority patent/GB201318880D0/en
Priority claimed from GB201318885A external-priority patent/GB201318885D0/en
Priority claimed from GBGB1322851.5A external-priority patent/GB201322851D0/en
Priority claimed from GB201401159A external-priority patent/GB201401159D0/en
Priority claimed from GB201406470A external-priority patent/GB201406470D0/en
Application filed by Psioxus Therapeutics Ltd filed Critical Psioxus Therapeutics Ltd
Publication of CL2016000959A1 publication Critical patent/CL2016000959A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

ADENOVIRUS DEL GRUPO B QUE COMPRENDEN GENES HETEROLOGOS; COMPOSICIÓN QUE LOS COMPRENDE; Y MÉTODO DE TRATAMIENTO.
CL2016000959A 2013-10-25 2016-04-21 Adenovirus oncolíticos armados con genes heterologos CL2016000959A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1318880.0A GB201318880D0 (en) 2013-10-25 2013-10-25 Adenovirus
GB201318885A GB201318885D0 (en) 2013-10-25 2013-10-25 Adenovirus
GBGB1322851.5A GB201322851D0 (en) 2013-12-23 2013-12-23 Method
GB201401159A GB201401159D0 (en) 2014-01-23 2014-01-23 Adenovirus
GB201406470A GB201406470D0 (en) 2014-04-10 2014-04-10 Virus

Publications (1)

Publication Number Publication Date
CL2016000959A1 true CL2016000959A1 (es) 2016-12-02

Family

ID=51900851

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016000959A CL2016000959A1 (es) 2013-10-25 2016-04-21 Adenovirus oncolíticos armados con genes heterologos

Country Status (30)

Country Link
US (3) US9987314B2 (es)
EP (3) EP3021859B1 (es)
KR (1) KR102272932B1 (es)
CN (2) CN114457044A (es)
AU (1) AU2014338864C1 (es)
CA (2) CA3183645A1 (es)
CL (1) CL2016000959A1 (es)
CY (1) CY1119955T1 (es)
DK (1) DK3021859T3 (es)
EA (1) EA036414B1 (es)
ES (1) ES2661132T3 (es)
HR (1) HRP20180317T1 (es)
HU (1) HUE035875T2 (es)
IL (2) IL244944B (es)
LT (1) LT3021859T (es)
MX (1) MX2016005170A (es)
MY (1) MY175614A (es)
NO (1) NO3021859T3 (es)
NZ (1) NZ718931A (es)
PE (1) PE20160951A1 (es)
PH (1) PH12016500759B1 (es)
PL (1) PL3021859T3 (es)
PT (1) PT3021859T (es)
RS (1) RS57043B1 (es)
SA (1) SA516371011B1 (es)
SG (2) SG11201602887QA (es)
SI (1) SI3021859T1 (es)
TR (1) TR201802728T4 (es)
WO (1) WO2015059303A1 (es)
ZA (1) ZA201603646B (es)

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KR20210118757A (ko) * 2020-03-23 2021-10-01 (주)큐리진 STAT3 및 mTOR를 이중 특이적으로 표적하는 핵산서열을 포함한 항암 바이러스
KR20210118760A (ko) * 2020-03-23 2021-10-01 (주)큐리진 AR 및 mTOR를 이중 특이적으로 표적하는 핵산분자를 포함하는 항암바이러스
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