CH659473A5 - Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten. - Google Patents

Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten. Download PDF

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Publication number
CH659473A5
CH659473A5 CH4935/85A CH493585A CH659473A5 CH 659473 A5 CH659473 A5 CH 659473A5 CH 4935/85 A CH4935/85 A CH 4935/85A CH 493585 A CH493585 A CH 493585A CH 659473 A5 CH659473 A5 CH 659473A5
Authority
CH
Switzerland
Prior art keywords
alk
silybin
formula
silibinin
compound
Prior art date
Application number
CH4935/85A
Other languages
German (de)
English (en)
Inventor
Reinhard Dr Braatz
Klaus Dr Goerler
Guenter Dr Halbach
Hartwig Dr Soicke
Karlheinz Prof Dr Dr Schmidt
Original Assignee
Madaus & Co Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr
Publication of CH659473A5 publication Critical patent/CH659473A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Silicon Compounds (AREA)
CH4935/85A 1984-11-22 1985-11-19 Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten. CH659473A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843442639 DE3442639A1 (de) 1984-11-22 1984-11-22 Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten

Publications (1)

Publication Number Publication Date
CH659473A5 true CH659473A5 (de) 1987-01-30

Family

ID=6250903

Family Applications (1)

Application Number Title Priority Date Filing Date
CH4935/85A CH659473A5 (de) 1984-11-22 1985-11-19 Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten.

Country Status (29)

Country Link
JP (1) JPS61143377A (fr)
KR (1) KR870001020B1 (fr)
AR (1) AR240931A1 (fr)
AT (1) AT393268B (fr)
BE (1) BE903693A (fr)
CA (1) CA1337124C (fr)
CH (1) CH659473A5 (fr)
CS (1) CS273610B2 (fr)
DD (1) DD259191A1 (fr)
DE (1) DE3442639A1 (fr)
DK (1) DK164865C (fr)
EG (1) EG19424A (fr)
ES (1) ES8609311A1 (fr)
FI (1) FI84064C (fr)
FR (1) FR2573427B1 (fr)
GB (1) GB2167414B (fr)
HU (1) HU195503B (fr)
IE (1) IE58791B1 (fr)
IT (1) IT1190426B (fr)
LU (1) LU86163A1 (fr)
MX (1) MX168415B (fr)
NL (1) NL192387C (fr)
NO (1) NO160205C (fr)
PL (1) PL146890B1 (fr)
PT (1) PT81532B (fr)
SE (1) SE465676B (fr)
SU (1) SU1436875A3 (fr)
YU (1) YU43689B (fr)
ZA (1) ZA858951B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716918D0 (en) * 1987-07-17 1987-08-26 Inverni Della Beffa Spa Soluble derivatives of silybin
US5262439A (en) * 1992-04-30 1993-11-16 The Regents Of The University Of California Soluble analogs of probucol
WO2006094357A1 (fr) * 2005-03-11 2006-09-14 Howard Florey Institute Of Experimental Physiology And Medicine Composes flavonoides et utilisations correspondantes
JP5349486B2 (ja) 2007-11-15 2013-11-20 マダウス ゲーエムベーハー 肝炎の治療のためのシリビニン成分
RU2482844C2 (ru) * 2007-11-15 2013-05-27 Мадаус Гмбх Силибининовый компонент для лечения гепатита
DK2430017T3 (en) * 2009-05-14 2016-10-03 Madaus Gmbh PROCESS FOR THE PREPARATION OF AMORPHOUS silibinin.
CA3112680C (fr) 2012-07-05 2023-07-25 Nutramax Laboratories, Inc. Compositions comprenant un sulforaphane ou un precurseur de sulforaphane et un extrait ou une poudre de chardon marie
CN103113359B (zh) * 2013-02-22 2016-01-06 西安安健药业有限公司 水飞蓟宾二偏琥珀酸酯及其药用盐
CN103193768B (zh) * 2013-02-22 2016-03-30 西安安健药业有限公司 治疗肝病的水飞蓟宾二偏琥珀酸酯异构体
CN103172622B (zh) * 2013-02-22 2015-11-04 西安安健药业有限公司 水飞蓟宾二偏琥珀酸酯的活性异构体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963318A1 (de) * 1969-12-17 1971-06-24 Schwabe Willmar Gmbh & Co Silybinhalbester der Bernsteinsaeure und der Phthalsaeure,ihre Salze mit pharmakologisch vertraglichen Basen,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten

Also Published As

Publication number Publication date
SE8505487L (sv) 1986-05-23
YU43689B (en) 1989-10-31
EG19424A (en) 1995-02-28
SE8505487D0 (sv) 1985-11-20
DD259191A1 (de) 1988-08-17
AT393268B (de) 1991-09-25
DE3442639C2 (fr) 1989-08-10
NO160205B (no) 1988-12-12
FI854535A (fi) 1986-05-23
FI84064C (fi) 1991-10-10
ES549116A0 (es) 1986-09-01
DK164865C (da) 1993-01-18
SU1436875A3 (ru) 1988-11-07
PT81532A (de) 1985-12-01
ZA858951B (en) 1986-08-27
IE852808L (en) 1986-05-22
PT81532B (pt) 1987-11-11
DE3442639A1 (de) 1986-05-22
KR870001020B1 (ko) 1987-05-23
NL192387B (nl) 1997-03-03
AR240931A1 (es) 1991-03-27
GB2167414A (en) 1986-05-29
LU86163A1 (de) 1986-03-24
ES8609311A1 (es) 1986-09-01
FR2573427B1 (fr) 1989-03-10
IT1190426B (it) 1988-02-16
GB8528226D0 (en) 1985-12-18
DK537785D0 (da) 1985-11-21
IT8522932A0 (it) 1985-11-21
DK537785A (da) 1986-05-23
YU178685A (en) 1988-02-29
HU195503B (en) 1988-05-30
NO160205C (no) 1989-03-22
PL256374A1 (en) 1986-12-02
BE903693A (fr) 1986-05-22
GB2167414B (en) 1989-01-11
JPH0432073B2 (fr) 1992-05-28
NL8503171A (nl) 1986-06-16
FI84064B (fi) 1991-06-28
JPS61143377A (ja) 1986-07-01
PL146890B1 (en) 1989-03-31
SE465676B (sv) 1991-10-14
MX168415B (es) 1993-05-24
IE58791B1 (en) 1993-11-17
HUT40114A (en) 1986-11-28
CA1337124C (fr) 1995-09-26
CS837885A2 (en) 1990-08-14
DK164865B (da) 1992-08-31
AR240931A2 (es) 1991-03-27
ATA337185A (de) 1991-02-15
NO854655L (no) 1986-05-23
KR860004056A (ko) 1986-06-16
FR2573427A1 (fr) 1986-05-23
NL192387C (nl) 1997-07-04
FI854535A0 (fi) 1985-11-18
CS273610B2 (en) 1991-03-12

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Owner name: MADAUS AG

PL Patent ceased