CH644352A5 - Process for the preparation of peptides - Google Patents
Process for the preparation of peptides Download PDFInfo
- Publication number
- CH644352A5 CH644352A5 CH94977A CH94977A CH644352A5 CH 644352 A5 CH644352 A5 CH 644352A5 CH 94977 A CH94977 A CH 94977A CH 94977 A CH94977 A CH 94977A CH 644352 A5 CH644352 A5 CH 644352A5
- Authority
- CH
- Switzerland
- Prior art keywords
- formula
- gly
- peptide
- phe
- preparation
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims description 78
- 238000000034 method Methods 0.000 title claims description 45
- 238000002360 preparation method Methods 0.000 title claims description 41
- 102000004196 processed proteins & peptides Human genes 0.000 title claims description 34
- 230000008569 process Effects 0.000 title claims description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 99
- 150000003839 salts Chemical class 0.000 claims description 50
- -1 L-3,4-dihydroxyphenylalanyl Chemical group 0.000 claims description 43
- 150000001875 compounds Chemical class 0.000 claims description 38
- 239000002253 acid Substances 0.000 claims description 30
- 125000003412 L-alanyl group Chemical group [H]N([H])[C@@](C([H])([H])[H])(C(=O)[*])[H] 0.000 claims description 28
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims description 21
- 125000003798 L-tyrosyl group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] 0.000 claims description 20
- 125000002435 L-phenylalanyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims description 15
- 125000005907 alkyl ester group Chemical group 0.000 claims description 12
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- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims description 2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
- C07K14/702—Enkephalins with at least 1 amino acid in D-form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Biophysics (AREA)
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- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2900/76A GB1577114A (en) | 1976-01-26 | 1976-01-26 | Biologically active peptides |
| GB848176 | 1976-03-03 | ||
| GB4882176 | 1976-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH644352A5 true CH644352A5 (en) | 1984-07-31 |
Family
ID=27254145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH94977A CH644352A5 (en) | 1976-01-26 | 1977-01-26 | Process for the preparation of peptides |
Country Status (11)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003000A (en) * | 1975-05-27 | 1977-01-11 | Sperry Rand Corporation | Sinusoidal oscillator with electronically variable frequency |
| US4261888A (en) * | 1976-04-12 | 1981-04-14 | Sandoz Ltd. | Organic compounds |
| FR2359817A1 (fr) * | 1976-07-27 | 1978-02-24 | Reckitt & Colmann Prod Ltd | Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant |
| GB1532148A (en) * | 1976-08-09 | 1978-11-15 | Searle & Co | 1-substituted enkepholin derivatives |
| HU178001B (en) * | 1976-09-16 | 1982-02-28 | Gyogyszekutato Intezet | Process for preparing new pentapeptides with morphine-like activity and derivatives thereof |
| DE2819277A1 (de) * | 1977-05-16 | 1978-11-23 | Sandoz Ag | Neue polypeptidderivate, ihre herstellung und verwendung |
| GB2000784B (en) * | 1977-07-05 | 1982-01-20 | American Home Prod | Analgesic polypetide |
| DE2862327D1 (en) * | 1977-07-22 | 1983-11-10 | Wellcome Found | Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them |
| US4264491A (en) * | 1977-10-03 | 1981-04-28 | Eli Lilly And Company | Analgesic compounds |
| HU182051B (en) * | 1978-05-02 | 1983-12-28 | Takeda Chemical Industries Ltd | Process for preparing tetrapeptide-hydrazyde derivatives |
| US4278596A (en) * | 1978-08-08 | 1981-07-14 | American Home Products Corporation | Analgesic pentapeptides |
| CA1175810A (en) * | 1979-03-30 | 1984-10-09 | Frank A. Momany | Synthetic peptides having pituitary growth hormone releasing activity |
| US4247543A (en) * | 1979-04-09 | 1981-01-27 | Sandoz Ltd. | Organic compounds |
| US4396606A (en) * | 1979-11-05 | 1983-08-02 | Addiction Research Foundation | Novel polypeptide analgesics |
| DE3163199D1 (en) * | 1980-07-17 | 1984-05-24 | Sandoz Ag | Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use |
| FR2488253A1 (fr) * | 1980-08-08 | 1982-02-12 | Roques Bernard | Nouveaux peptides et leur application en therapeutique |
| BR8208035A (pt) * | 1981-12-28 | 1983-11-22 | Beckman Instruments Inc | Peptideos sinteticos tendo atividade liberadora de hormonio do crescimento da pituitaria |
| US4491541A (en) * | 1982-11-10 | 1985-01-01 | Farmitalia Carlo Erba | Peptides |
| JPH0680079B2 (ja) * | 1984-11-09 | 1994-10-12 | エーザイ株式会社 | ポリペプチド |
| AU618029B2 (en) * | 1987-11-02 | 1991-12-12 | Imperial Chemical Industries Plc | Polypeptide compounds |
| NZ258345A (en) * | 1992-11-12 | 1996-03-26 | Biomeasure Inc | Peptides (opioid) capable of selectively binding to cell receptors |
| WO2010120691A2 (en) * | 2009-04-13 | 2010-10-21 | Elc Management Llc | Methionine sulfoxide peptide, compositions and methods of use |
| TW201920234A (zh) | 2017-09-11 | 2019-06-01 | 美商領導醫療有限公司 | 類鴉片促效劑肽及其用途 |
-
1977
- 1977-01-26 HU HU77WE548A patent/HU184704B/hu unknown
- 1977-01-26 JP JP763777A patent/JPS5291839A/ja active Pending
- 1977-01-26 CH CH94977A patent/CH644352A5/de not_active IP Right Cessation
- 1977-01-26 FR FR7702122A patent/FR2338925A1/fr active Granted
- 1977-01-26 DK DK33177A patent/DK33177A/da not_active Application Discontinuation
- 1977-01-26 FI FI770254A patent/FI70228C/fi not_active IP Right Cessation
- 1977-01-26 ES ES455365A patent/ES455365A1/es not_active Expired
- 1977-01-26 IL IL51332A patent/IL51332A/xx unknown
- 1977-01-26 NL NL7700785A patent/NL7700785A/xx not_active Application Discontinuation
- 1977-01-26 DE DE19772703109 patent/DE2703109A1/de not_active Ceased
- 1977-07-21 SE SE7708404A patent/SE7708404L/ unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7700785A (nl) | 1977-07-28 |
| SE7708404L (sv) | 1977-07-27 |
| IL51332A0 (en) | 1977-03-31 |
| JPS5291839A (en) | 1977-08-02 |
| ES455365A1 (es) | 1978-05-16 |
| FI770254A7 (enrdf_load_stackoverflow) | 1977-07-27 |
| HU184704B (en) | 1984-10-29 |
| FR2338925A1 (fr) | 1977-08-19 |
| FR2338925B1 (enrdf_load_stackoverflow) | 1980-08-08 |
| DE2703109A1 (de) | 1977-08-04 |
| IL51332A (en) | 1980-09-16 |
| DK33177A (da) | 1977-07-27 |
| FI70228C (fi) | 1986-09-15 |
| FI70228B (fi) | 1986-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |