CH616402A5 - Process for the preparation of analogues of somatostatin - Google Patents

Process for the preparation of analogues of somatostatin Download PDF

Info

Publication number
CH616402A5
CH616402A5 CH706676A CH706676A CH616402A5 CH 616402 A5 CH616402 A5 CH 616402A5 CH 706676 A CH706676 A CH 706676A CH 706676 A CH706676 A CH 706676A CH 616402 A5 CH616402 A5 CH 616402A5
Authority
CH
Switzerland
Prior art keywords
gly
phe
boc
lys
thr
Prior art date
Application number
CH706676A
Other languages
English (en)
French (fr)
Inventor
Nedumparambil A Abraham
Hans Ueli Immer
Verner Robert Nelson
Kazimir Sestanj
Original Assignee
Ayerst Mckenna & Harrison
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/583,947 external-priority patent/US4081530A/en
Priority claimed from US05/594,159 external-priority patent/US4020157A/en
Application filed by Ayerst Mckenna & Harrison filed Critical Ayerst Mckenna & Harrison
Publication of CH616402A5 publication Critical patent/CH616402A5/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CH706676A 1975-06-04 1976-06-03 Process for the preparation of analogues of somatostatin CH616402A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/583,947 US4081530A (en) 1975-06-04 1975-06-04 Extended chain derivatives of somatostatin
US59415875A 1975-07-08 1975-07-08
US05/594,159 US4020157A (en) 1975-07-08 1975-07-08 Shortened analogs of somatostatin

Publications (1)

Publication Number Publication Date
CH616402A5 true CH616402A5 (en) 1980-03-31

Family

ID=27416418

Family Applications (1)

Application Number Title Priority Date Filing Date
CH706676A CH616402A5 (en) 1975-06-04 1976-06-03 Process for the preparation of analogues of somatostatin

Country Status (10)

Country Link
JP (1) JPS5236682A (enrdf_load_stackoverflow)
CH (1) CH616402A5 (enrdf_load_stackoverflow)
CS (1) CS207570B2 (enrdf_load_stackoverflow)
DE (1) DE2625330A1 (enrdf_load_stackoverflow)
FR (1) FR2313077A1 (enrdf_load_stackoverflow)
GB (1) GB1545818A (enrdf_load_stackoverflow)
IL (1) IL49731A0 (enrdf_load_stackoverflow)
NL (1) NL7606008A (enrdf_load_stackoverflow)
SE (1) SE7606314L (enrdf_load_stackoverflow)
SU (1) SU639446A3 (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115043928A (zh) * 2022-06-22 2022-09-13 四川吉晟生物医药有限公司 一种生长抑素的制备方法
FR3155702A1 (fr) 2023-11-27 2025-05-30 Id4Us Dispositif de capture à ultrasons et à dispense de lubrifiant sur sa surface de capture

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904594A (en) * 1973-07-02 1975-09-09 Salk Inst For Biological Studi Somatostatin and acylated des-(ala' 1', gly' 2') derivatives thereof
DE2416048A1 (de) * 1974-04-03 1975-10-30 Hoechst Ag Neue peptide mit biologischer wirkung
DE2519656A1 (de) * 1974-05-13 1975-11-27 Sandoz Ag Neue peptide und verfahren zu ihrer herstellung
US3931140A (en) * 1975-01-27 1976-01-06 American Home Products Corporation (H-gly-gly-tyr-ala)1 -somatostatin

Also Published As

Publication number Publication date
CS207570B2 (en) 1981-08-31
SU639446A3 (ru) 1978-12-25
SE7606314L (sv) 1976-12-05
IL49731A0 (en) 1976-08-31
JPS5236682A (en) 1977-03-22
FR2313077A1 (fr) 1976-12-31
GB1545818A (en) 1979-05-16
FR2313077B1 (enrdf_load_stackoverflow) 1978-11-17
DE2625330A1 (de) 1976-12-16
NL7606008A (nl) 1976-12-07

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