CH612197A5 - Process for the preparation of novel substituted 6-aryl-4H-s-triazolo[3,4-c]thieno[2,3-e]-1,4-diazepines - Google Patents
Process for the preparation of novel substituted 6-aryl-4H-s-triazolo[3,4-c]thieno[2,3-e]-1,4-diazepinesInfo
- Publication number
- CH612197A5 CH612197A5 CH26879A CH26879A CH612197A5 CH 612197 A5 CH612197 A5 CH 612197A5 CH 26879 A CH26879 A CH 26879A CH 26879 A CH26879 A CH 26879A CH 612197 A5 CH612197 A5 CH 612197A5
- Authority
- CH
- Switzerland
- Prior art keywords
- thieno
- aryl
- diazepines
- triazolo
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel substituted 6-aryl-4H-s-triazolo[3,4-c]thieno[2,3-e]- 1,4-diazepines of the accompanying formula I, in which the symbols R<1>, R<2> and R<3> have the meaning given in Patent Claim 1, are prepared by reaction of a corresponding 5-aryl-2-hydrazino-3H-[2,3-e]thieno-1,4-diazepine with an acid of the formula R<3>-COOH or a functional derivative of this acid with simultaneous cyclisation. The compounds of the formula I and their acid addition salts have useful therapeutic properties. They have an anxiolytic, antispasmodic and muscle-relaxant action and moreover exhibit an intensive anticonvulsive action.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2410030A DE2410030C3 (en) | 1974-03-02 | 1974-03-02 | 8-Bromo-6-phenyl-4H-s-triazolo [3,4-c] thieno [2,3-e] 1,4-diazepines, processes for their preparation and pharmaceutical compositions containing them |
DE2435041A DE2435041C3 (en) | 1974-07-20 | 1974-07-20 | 8-Substituted 6-aryl-4H-s-triazolo [3,4c] thieno [23e] 1,4-diazepines, process for their preparation, their use in medicaments and pharmaceutical preparations containing them |
DE19742445430 DE2445430B2 (en) | 1974-07-20 | 1974-09-24 | 1 - SUBSTITUTED 6-ARYL-4H-STRIAZOLO SQUARE CLIP ON 3.4C SQUARE BRACKET TO THIENO SQUARE BRACKET ON 2.3 SQUARE BRACKET TO 1,4-DIAZEPINE, METHOD OF MANUFACTURING THEM AND MEDICINAL PRODUCTS CONTAINING THESE |
DE2460776A DE2460776C2 (en) | 1974-07-20 | 1974-12-21 | 1-substituted 6-aryl-4H-s-triazolo- (3,4c) -thieno- (2,3e) -1,4-diazepines, processes for their production, pharmaceutical preparations containing them and intermediates and processes for the production of these intermediates |
CH251075A CH611900A5 (en) | 1974-03-02 | 1975-02-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH612197A5 true CH612197A5 (en) | 1979-07-13 |
Family
ID=27509061
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH26979A CH611901A5 (en) | 1974-03-02 | 1975-02-27 | Process for the preparation of novel substituted 6-aryl-4H-s-triazolo[3,4-c]thieno[2,3-e]-1,4-diazepines |
CH26879A CH612197A5 (en) | 1974-03-02 | 1975-02-27 | Process for the preparation of novel substituted 6-aryl-4H-s-triazolo[3,4-c]thieno[2,3-e]-1,4-diazepines |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH26979A CH611901A5 (en) | 1974-03-02 | 1975-02-27 | Process for the preparation of novel substituted 6-aryl-4H-s-triazolo[3,4-c]thieno[2,3-e]-1,4-diazepines |
Country Status (1)
Country | Link |
---|---|
CH (2) | CH611901A5 (en) |
-
1975
- 1975-02-27 CH CH26979A patent/CH611901A5/en not_active IP Right Cessation
- 1975-02-27 CH CH26879A patent/CH612197A5/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CH611901A5 (en) | 1979-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |