CH610903A5 - Process for the preparation of cephalosporanic acid derivatives - Google Patents
Process for the preparation of cephalosporanic acid derivativesInfo
- Publication number
- CH610903A5 CH610903A5 CH963977A CH963977A CH610903A5 CH 610903 A5 CH610903 A5 CH 610903A5 CH 963977 A CH963977 A CH 963977A CH 963977 A CH963977 A CH 963977A CH 610903 A5 CH610903 A5 CH 610903A5
- Authority
- CH
- Switzerland
- Prior art keywords
- denotes
- compounds
- preparation
- acid derivatives
- cephalosporanic acid
- Prior art date
Links
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical class 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP48037205A JPS5939439B2 (ja) | 1973-03-30 | 1973-03-30 | ７−置換−３−ｎ，ｓ含有複素環チオメチル−３−セフエム−４−カルボン酸誘導体の製造法 |
| JP48073898A JPS5852997B2 (ja) | 1973-06-29 | 1973-06-29 | ７− チカン −３− ヒドロキシアルキルチカンフクソカンチオメチル −３− セフエム −４− カルボンサンルイノ セイゾウホウ |
| JP13936473A JPS5716118B2 (enrdf_load_stackoverflow) | 1973-12-12 | 1973-12-12 | |
| JP741096A JPS5734837B2 (enrdf_load_stackoverflow) | 1973-12-26 | 1973-12-26 | |
| JP1308374A JPS5732074B2 (enrdf_load_stackoverflow) | 1974-01-30 | 1974-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH610903A5 true CH610903A5 (en) | 1979-05-15 |
Family
ID=27518056
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH963977A CH610903A5 (en) | 1973-03-30 | 1974-03-29 | Process for the preparation of cephalosporanic acid derivatives |
| CH963877A CH610902A5 (en) | 1973-03-30 | 1974-03-29 | Process for the preparation of cephalosporanic acid derivatives |
| CH442874A CH595388A5 (enrdf_load_stackoverflow) | 1973-03-30 | 1974-03-29 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH963877A CH610902A5 (en) | 1973-03-30 | 1974-03-29 | Process for the preparation of cephalosporanic acid derivatives |
| CH442874A CH595388A5 (enrdf_load_stackoverflow) | 1973-03-30 | 1974-03-29 |
Country Status (10)
| Country | Link |
|---|---|
| AR (1) | AR207752A1 (enrdf_load_stackoverflow) |
| BE (1) | BE812951A (enrdf_load_stackoverflow) |
| CH (3) | CH610903A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2415402C2 (enrdf_load_stackoverflow) |
| FR (1) | FR2223002B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1461948A (enrdf_load_stackoverflow) |
| NL (1) | NL180422C (enrdf_load_stackoverflow) |
| NO (2) | NO741137L (enrdf_load_stackoverflow) |
| NZ (1) | NZ173837A (enrdf_load_stackoverflow) |
| SE (1) | SE428297B (enrdf_load_stackoverflow) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4379924A (en) | 1973-12-25 | 1983-04-12 | Takeda Chemical Industries, Ltd. | Cephalosporin derivatives |
| US4093723A (en) | 1976-05-19 | 1978-06-06 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins |
| BE845338A (fr) * | 1975-09-02 | 1977-02-21 | Nouvelles cephalosporines, procede pour leur obtention et application pharmaceutique | |
| US4171433A (en) * | 1975-10-30 | 1979-10-16 | Smithkline Corporation | 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins |
| US4171362A (en) * | 1975-10-30 | 1979-10-16 | Smithkline Corporation | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them |
| IL50546A (en) * | 1975-10-30 | 1980-07-31 | Smithkline Corp | 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them |
| US4118491A (en) * | 1976-03-11 | 1978-10-03 | Smithkline Corporation | 7-Acyl-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them |
| US4171368A (en) * | 1975-10-30 | 1979-10-16 | Smithkline Corporation | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them |
| US4101656A (en) | 1976-07-12 | 1978-07-18 | Smithkline Corporation | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them |
| US4066762A (en) * | 1976-07-12 | 1978-01-03 | Smithkline Corporation | Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid |
| US4083975A (en) | 1976-09-24 | 1978-04-11 | Smithkline Corporation | 7-Acylamino-3-(3-sulfomethyl-1,2,4-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids |
| US4064242A (en) * | 1976-11-04 | 1977-12-20 | Smithkline Corporation | 7-Acylamino-3-[1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl]-3-cephem-4-carboxylic acids |
| US4117123A (en) * | 1977-06-09 | 1978-09-26 | Smithkline Corporation | 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids |
| US4260815A (en) | 1979-10-09 | 1981-04-07 | American Cyanamid Company | Process for preparing a solution of DL-mandelic acid |
| US4259521A (en) | 1979-10-09 | 1981-03-31 | American Cyanamid Company | Process for resolving DL-mandelic acid |
| EP1238971A4 (en) * | 1999-12-16 | 2003-02-26 | Sumitomo Pharma | SUBSTITUTED GUANIDINE DERIVATIVES |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
| DE1953861C2 (de) * | 1969-10-25 | 1982-12-23 | Fujisawa Pharmaceutical Co., Ltd., Osaka | 7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren |
| US3757014A (en) * | 1971-05-07 | 1973-09-04 | Bristol Myers Co | Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl - |
-
1974
- 1974-01-01 AR AR253054A patent/AR207752A1/es active
- 1974-03-28 BE BE142549A patent/BE812951A/xx not_active IP Right Cessation
- 1974-03-29 CH CH963977A patent/CH610903A5/xx not_active IP Right Cessation
- 1974-03-29 CH CH963877A patent/CH610902A5/xx not_active IP Right Cessation
- 1974-03-29 SE SE7404306A patent/SE428297B/xx unknown
- 1974-03-29 CH CH442874A patent/CH595388A5/xx not_active IP Right Cessation
- 1974-03-29 FR FR7411408A patent/FR2223002B1/fr not_active Expired
- 1974-03-29 NL NLAANVRAGE7404330,A patent/NL180422C/xx not_active IP Right Cessation
- 1974-03-29 NO NO741137A patent/NO741137L/no unknown
- 1974-03-29 NZ NZ173837A patent/NZ173837A/xx unknown
- 1974-03-29 DE DE2415402A patent/DE2415402C2/de not_active Expired
- 1974-03-29 GB GB1414374A patent/GB1461948A/en not_active Expired
-
1980
- 1980-05-12 NO NO80801402A patent/NO801402L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE812951A (fr) | 1974-09-30 |
| GB1461948A (en) | 1977-01-19 |
| NZ173837A (en) | 1978-07-28 |
| FR2223002B1 (enrdf_load_stackoverflow) | 1977-11-04 |
| FR2223002A1 (enrdf_load_stackoverflow) | 1974-10-25 |
| DE2415402A1 (de) | 1974-10-03 |
| NO801402L (no) | 1974-10-01 |
| CH595388A5 (enrdf_load_stackoverflow) | 1978-02-15 |
| NL180422B (nl) | 1986-09-16 |
| CH610902A5 (en) | 1979-05-15 |
| NO741137L (no) | 1974-10-01 |
| AR207752A1 (es) | 1976-10-29 |
| SE428297B (sv) | 1983-06-20 |
| DE2415402C2 (de) | 1985-12-19 |
| NL180422C (nl) | 1987-02-16 |
| NL7404330A (enrdf_load_stackoverflow) | 1974-10-02 |
| AU6735374A (en) | 1975-10-02 |
| SE7404306L (enrdf_load_stackoverflow) | 1974-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |