CH585227A5 - Antibacterial penicillin and cephalosporin analogues - contg substd pyrimi-dine-carboxamido or-acetamido gp - Google Patents

Antibacterial penicillin and cephalosporin analogues - contg substd pyrimi-dine-carboxamido or-acetamido gp

Info

Publication number
CH585227A5
CH585227A5 CH1425772A CH1425772A CH585227A5 CH 585227 A5 CH585227 A5 CH 585227A5 CH 1425772 A CH1425772 A CH 1425772A CH 1425772 A CH1425772 A CH 1425772A CH 585227 A5 CH585227 A5 CH 585227A5
Authority
CH
Switzerland
Prior art keywords
substd
opt
pyrimi
dine
carboxamido
Prior art date
Application number
CH1425772A
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH1425772A priority Critical patent/CH585227A5/en
Priority to AR250301A priority patent/AR208171A1/en
Priority to IL42174A priority patent/IL42174A/en
Priority to IL43174A priority patent/IL43174A0/en
Priority to IE1588/73A priority patent/IE38222B1/en
Priority to ZA737223*A priority patent/ZA737223B/en
Priority to CA180,798A priority patent/CA1074295A/en
Priority to US05/398,512 priority patent/US4015000A/en
Priority to GB4434473A priority patent/GB1440216A/en
Priority to DE19732347533 priority patent/DE2347533A1/en
Priority to DD173731A priority patent/DD107288A5/xx
Priority to NL7313347A priority patent/NL7313347A/xx
Priority to AU60780/73A priority patent/AU489262B2/en
Priority to AT834873A priority patent/AT328614B/en
Priority to BE136150A priority patent/BE805443A/en
Priority to FR7334803A priority patent/FR2201075B1/fr
Priority to AT89875*A priority patent/ATA89875A/en
Priority to AT89875A priority patent/AT329184B/en
Priority to ES419189A priority patent/ES419189A1/en
Priority to SE7611410A priority patent/SE7611410L/en
Publication of CH585227A5 publication Critical patent/CH585227A5/en
Priority to US05/900,696 priority patent/US4202900A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Cpds. of formula (I): (where-S-A- is a residue of formulae (A) or (B): R3 is free or esterified COOH; R4 is H, lower alkoxy or opt. substd. methyl; R1 is H and R2 is opt. substd. phenyl, thienyl or furyl, or CR1-R2 is opt. substd. 4-7 C cycloalkyl; n and m are 0 or 1; B is opt. substd. 2,6-dioxo-or 2,6-dithioxo- or 2-thioxo-6-oxo-1,2,3,6-tetrahydropyrimidyl, 2,6-dihydroxy- or 2,6-dimercapto- or 2-mercapto-6-hydroxy- or 2,6-diamino- or 2-amino-6-hydroxy-or 2,6-dihalopyrimidyl, each bonded via the 4 or 5 posn.) are antibacterial cpds. esp. active against Gram-negative bacteria. They can be prepd. by standard methods, e.g., by reacting the corresp. 6-APA or 7-ACA with B(CH2)m-CONHCR,R2COOH.
CH1425772A 1972-09-27 1972-09-29 Antibacterial penicillin and cephalosporin analogues - contg substd pyrimi-dine-carboxamido or-acetamido gp CH585227A5 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
CH1425772A CH585227A5 (en) 1972-09-29 1972-09-29 Antibacterial penicillin and cephalosporin analogues - contg substd pyrimi-dine-carboxamido or-acetamido gp
AR250301A AR208171A1 (en) 1972-09-29 1973-01-01 PROCEDURE FOR OBTAINING NEW DERIVATIVES OF CEF-3-EM-4-CARBOXYL ACID
IL42174A IL42174A (en) 1972-09-29 1973-05-02 Substituted pyrimidine derivatives of penam-3-carbcoxylic acid and cephem-4-carbocyclic acid their manufacture and pharmaceutical compositions containing them
IL43174A IL43174A0 (en) 1972-09-29 1973-09-06 New derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid their manufacture and pharmaceutical compositions containing them
IE1588/73A IE38222B1 (en) 1972-09-29 1973-09-06 Derivatives of penam-3-carboxylic acid and cephem-4-carboxylicacid and processes for their manufacture
ZA737223*A ZA737223B (en) 1972-09-29 1973-09-11 New derivatives of peman-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture
CA180,798A CA1074295A (en) 1972-09-29 1973-09-11 Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture
US05/398,512 US4015000A (en) 1972-09-29 1973-09-18 6-Acylamino-penam-3-carboxylic and 7-acylamino-3-cephem-4-carboxylic acids
DE19732347533 DE2347533A1 (en) 1972-09-29 1973-09-21 NEW DERIVATIVES OF PENAM-3-CARBONIC ACID AND CEPHEM-4-CARBONIC ACID AND THE PROCESS FOR THEIR PRODUCTION
GB4434473A GB1440216A (en) 1972-09-29 1973-09-21 Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture
DD173731A DD107288A5 (en) 1972-09-29 1973-09-27
NL7313347A NL7313347A (en) 1972-09-29 1973-09-27
AU60780/73A AU489262B2 (en) 1973-09-27 new DERIVATIVES OF PENAM-3-CARBOXYLIC ACID AND CEPHEM-4-CARBOXYLIC ACID AND PROCESSES FOR THEIR MANUFACTURE
FR7334803A FR2201075B1 (en) 1972-09-29 1973-09-28
BE136150A BE805443A (en) 1972-09-29 1973-09-28 NEW DENAM-3-CARBOXYLIC ACID AND CEPHEM-4-CARBOXYLIC ACID DERIVATIVES AND METHODS FOR THEIR PREPARATION
AT834873A AT328614B (en) 1972-09-29 1973-09-28 PROCESS FOR THE PREPARATION OF NEW DERIVATIVES OF PENAM-3-CARBONIC ACID AND CEPHEM-4-CARBONIC ACID
AT89875*A ATA89875A (en) 1972-09-29 1973-09-28 PROCESS FOR PRODUCING NEW DERIVATIVES OF PENAM-3 AND CEPHEM-4 CARBONIC ACID
AT89875A AT329184B (en) 1972-09-29 1973-09-28 PROCESS FOR PRODUCING NEW DERIVATIVES OF PENAM-3 AND CEPHEM-4 CARBONIC ACID
ES419189A ES419189A1 (en) 1972-09-29 1973-09-28 Procedure for the obtaining of derivatives of penam-3-carboxylic acids and acids cefem-4-carboxilicos. (Machine-translation by Google Translate, not legally binding)
SE7611410A SE7611410L (en) 1972-09-29 1976-10-14 PROCEDURE FOR PREPARING NEW PERAM-3-CARBOXYLIC ACID DERIVATIVES
US05/900,696 US4202900A (en) 1972-09-27 1978-04-28 Derivatives of penam-3-carboxylic acid and a pharmaceutical composition containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1425772A CH585227A5 (en) 1972-09-29 1972-09-29 Antibacterial penicillin and cephalosporin analogues - contg substd pyrimi-dine-carboxamido or-acetamido gp

Publications (1)

Publication Number Publication Date
CH585227A5 true CH585227A5 (en) 1977-02-28

Family

ID=4399328

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1425772A CH585227A5 (en) 1972-09-27 1972-09-29 Antibacterial penicillin and cephalosporin analogues - contg substd pyrimi-dine-carboxamido or-acetamido gp

Country Status (3)

Country Link
BE (1) BE805443A (en)
CH (1) CH585227A5 (en)
ZA (1) ZA737223B (en)

Also Published As

Publication number Publication date
BE805443A (en) 1974-03-28
ZA737223B (en) 1974-08-28

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Legal Events

Date Code Title Description
PL Patent ceased