CH498122A - Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates - Google Patents
Verfahren zur Herstellung eines neuen TetrahydroazepinderivatesInfo
- Publication number
- CH498122A CH498122A CH197668A CH197668A CH498122A CH 498122 A CH498122 A CH 498122A CH 197668 A CH197668 A CH 197668A CH 197668 A CH197668 A CH 197668A CH 498122 A CH498122 A CH 498122A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- new
- tetrahydroazepine derivative
- tetrahydroazepine
- derivative
- Prior art date
Links
- SCEIUGQQBYRBPP-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-azepine Chemical class C1CCC=CNC1 SCEIUGQQBYRBPP-UHFFFAOYSA-N 0.000 title 1
Classifications
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
 
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| CH197668A CH498122A (de) | 1968-02-09 | 1968-02-09 | Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates | 
| IL30458A IL30458A (en) | 1968-02-09 | 1968-07-29 | 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it | 
| NL6811311A NL6811311A (forum.php) | 1968-02-09 | 1968-08-08 | |
| DK383268AA DK123526B (da) | 1968-02-09 | 1968-08-08 | Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf. | 
| FR163036A FR7915M (forum.php) | 1967-02-17 | 1968-08-14 | |
| ES357247A ES357247A1 (es) | 1968-02-09 | 1968-08-14 | Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina. | 
| AT797568A AT277257B (de) | 1968-02-09 | 1968-08-14 | Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates sowie seiner Säureadditionssalze | 
| GB38772/68A GB1225053A (en) | 1968-02-09 | 1968-08-14 | New tetrahydroazepine derivative, process for its production and compositions containing same | 
| DE19681795132 DE1795132A1 (de) | 1968-02-09 | 1968-08-14 | Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates | 
| FR1598948D FR1598948A (forum.php) | 1968-02-09 | 1968-08-14 | |
| BE719631D BE719631A (forum.php) | 1968-02-09 | 1968-08-16 | 
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| CH197668A CH498122A (de) | 1968-02-09 | 1968-02-09 | Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates | 
Publications (1)
| Publication Number | Publication Date | 
|---|---|
| CH498122A true CH498122A (de) | 1970-10-31 | 
Family
ID=4223010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| CH197668A CH498122A (de) | 1967-02-17 | 1968-02-09 | Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates | 
Country Status (10)
| Country | Link | 
|---|---|
| AT (1) | AT277257B (forum.php) | 
| BE (1) | BE719631A (forum.php) | 
| CH (1) | CH498122A (forum.php) | 
| DE (1) | DE1795132A1 (forum.php) | 
| DK (1) | DK123526B (forum.php) | 
| ES (1) | ES357247A1 (forum.php) | 
| FR (1) | FR1598948A (forum.php) | 
| GB (1) | GB1225053A (forum.php) | 
| IL (1) | IL30458A (forum.php) | 
| NL (1) | NL6811311A (forum.php) | 
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| DE2207430C3 (de) * | 1972-02-14 | 1982-05-13 | Pennwalt Corp., 19102 Philadelphia, Pa. | 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel | 
| US4160765A (en) * | 1976-11-17 | 1979-07-10 | Smithkline Corporation | Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds | 
| US4197297A (en) * | 1976-11-17 | 1980-04-08 | Smithkline Corporation | 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines | 
| US4171359A (en) * | 1978-04-12 | 1979-10-16 | Smithkline Corporation | Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | 
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators | 
| MXPA05013366A (es) | 2003-06-17 | 2006-04-05 | Arena Pharm Inc | Derivados de benzazepina utiles para el tratamiento de enfermedades asociadas con el receptor 5ht2c. | 
| EP2332919A3 (en) | 2003-06-17 | 2011-10-19 | Arena Pharmaceuticals, Inc. | Processes for preparing 3-benzazepines | 
| TW200510324A (en) * | 2003-08-11 | 2005-03-16 | Lilly Co Eli | 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist | 
| PT1838677E (pt) | 2004-12-21 | 2009-11-16 | Arena Pharm Inc | Formas cristalinas do cloridrato de (r)-8-cloro-1-metil- 2,3,4,5-tetra-hidro-1h-3-benzazepina | 
| PT1833473E (pt) | 2004-12-23 | 2009-12-17 | Arena Pharm Inc | Composições de modulador de receptor 5ht2c e métodos de utilização | 
| EP2518053A1 (en) | 2006-04-03 | 2012-10-31 | Arena Pharmaceuticals, Inc. | Process for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine | 
| WO2008070111A2 (en) | 2006-12-05 | 2008-06-12 | Arena Pharmaceuticals, Inc. | Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof | 
| EP2288585A1 (en) | 2008-03-04 | 2011-03-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine | 
| US8952197B2 (en) | 2009-06-18 | 2015-02-10 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-HT2C receptor agonists | 
| US9045431B2 (en) | 2010-06-02 | 2015-06-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-HT2C receptor agonists | 
| EP2611782A1 (en) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids | 
| NZ630494A (en) | 2010-09-01 | 2016-05-27 | Arena Pharm Inc | Administration of lorcaserin to individuals with renal impairment | 
| KR20180118801A (ko) | 2010-09-01 | 2018-10-31 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 체중 관리에 유용한 5-ht2c 작동제의 변형-방출 투여 형태 | 
| KR20130101524A (ko) | 2010-09-01 | 2013-09-13 | 아레나 파마슈티칼스, 인크. | 5-ht2c 아고니스트의 비-흡습성 염 | 
| MX2015004532A (es) | 2012-10-09 | 2016-01-20 | Arena Pharm Inc | Metodo de control del peso. | 
- 
        1968
        - 1968-02-09 CH CH197668A patent/CH498122A/de not_active IP Right Cessation
- 1968-07-29 IL IL30458A patent/IL30458A/en unknown
- 1968-08-08 DK DK383268AA patent/DK123526B/da unknown
- 1968-08-08 NL NL6811311A patent/NL6811311A/xx unknown
- 1968-08-14 DE DE19681795132 patent/DE1795132A1/de active Pending
- 1968-08-14 AT AT797568A patent/AT277257B/de not_active IP Right Cessation
- 1968-08-14 FR FR1598948D patent/FR1598948A/fr not_active Expired
- 1968-08-14 ES ES357247A patent/ES357247A1/es not_active Expired
- 1968-08-14 GB GB38772/68A patent/GB1225053A/en not_active Expired
- 1968-08-16 BE BE719631D patent/BE719631A/xx unknown
 
Also Published As
| Publication number | Publication date | 
|---|---|
| FR1598948A (forum.php) | 1970-07-15 | 
| DE1795132A1 (de) | 1972-01-05 | 
| BE719631A (forum.php) | 1969-02-17 | 
| NL6811311A (forum.php) | 1969-08-12 | 
| IL30458A0 (en) | 1968-09-26 | 
| AT277257B (de) | 1969-12-29 | 
| DK123526B (da) | 1972-07-03 | 
| GB1225053A (en) | 1971-03-17 | 
| ES357247A1 (es) | 1970-03-01 | 
| IL30458A (en) | 1972-03-28 | 
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Legal Events
| Date | Code | Title | Description | 
|---|---|---|---|
| PL | Patent ceased |