CH425763A - Préparation des N-(tertiaire-aminoalkyl) benzamides substitués - Google Patents

Préparation des N-(tertiaire-aminoalkyl) benzamides substitués

Info

Publication number
CH425763A
CH425763A CH820062A CH820062A CH425763A CH 425763 A CH425763 A CH 425763A CH 820062 A CH820062 A CH 820062A CH 820062 A CH820062 A CH 820062A CH 425763 A CH425763 A CH 425763A
Authority
CH
Switzerland
Prior art keywords
benzamides
aminoalkyl
tertiary
substituted
preparation
Prior art date
Application number
CH820062A
Other languages
English (en)
French (fr)
Inventor
Leon Thominet Michel
Marcel Laville Claude
Original Assignee
Soc Et Scient Et Ind De L Ile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Soc Et Scient Et Ind De L Ile filed Critical Soc Et Scient Et Ind De L Ile
Publication of CH425763A publication Critical patent/CH425763A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH820062A 1961-07-25 1962-07-09 Préparation des N-(tertiaire-aminoalkyl) benzamides substitués CH425763A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR869010A FR1313758A (fr) 1961-07-25 1961-07-25 Nouveaux benzamides substitués et leur procédé de préparation

Publications (1)

Publication Number Publication Date
CH425763A true CH425763A (fr) 1966-12-15

Family

ID=8760052

Family Applications (1)

Application Number Title Priority Date Filing Date
CH820062A CH425763A (fr) 1961-07-25 1962-07-09 Préparation des N-(tertiaire-aminoalkyl) benzamides substitués

Country Status (11)

Country Link
US (2) US3177252A (US20030204162A1-20031030-M00001.png)
JP (2) JPS5145651B1 (US20030204162A1-20031030-M00001.png)
BR (1) BR6240890D0 (US20030204162A1-20031030-M00001.png)
CH (1) CH425763A (US20030204162A1-20031030-M00001.png)
DK (1) DK106557C (US20030204162A1-20031030-M00001.png)
ES (1) ES278660A1 (US20030204162A1-20031030-M00001.png)
FI (1) FI42075B (US20030204162A1-20031030-M00001.png)
FR (1) FR1313758A (US20030204162A1-20031030-M00001.png)
NL (1) NL281394A (US20030204162A1-20031030-M00001.png)
OA (1) OA01153A (US20030204162A1-20031030-M00001.png)
SE (2) SE372009B (US20030204162A1-20031030-M00001.png)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL281394A (US20030204162A1-20031030-M00001.png) * 1961-07-25
GB1019781A (US20030204162A1-20031030-M00001.png) * 1963-03-05
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
US3885033A (en) * 1967-04-03 1975-05-20 Ile De France Method of anesthetizing a mammal by administration of a substituted 2-arylalkyloxy benzamide
US3509166A (en) * 1968-01-15 1970-04-28 American Cyanamid Co Tetrahydro-pyridine derivatives of benzamide
JPS4940459B1 (US20030204162A1-20031030-M00001.png) * 1970-12-21 1974-11-02
GB1399632A (en) * 1972-07-13 1975-07-02 Leo Pharm Prod Ltd Sulphamoyl-benzoic acids
CA1082181A (en) * 1976-06-03 1980-07-22 Eric A. Watts Benzamide derivatives
US4255580A (en) * 1976-08-04 1981-03-10 Siociete D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene bis (oxy) benzamides and derivatives
US4140769A (en) 1976-12-23 1979-02-20 Miles Laboratories, Inc. 3-Substituted salicylamides
US4109005A (en) * 1977-05-11 1978-08-22 A. H. Robins Company, Inc. Method of increasing rate of gastric emptying with pyrrolidinylbenzamides
JPS54130599A (en) * 1978-03-31 1979-10-09 Taisho Pharmaceut Co Ltd Furoindole derivative
JPS54148743A (en) * 1978-05-12 1979-11-21 Asahi Chem Ind Co Ltd Production of methoclopramide
JPS6058224B2 (ja) * 1978-07-31 1985-12-19 旭化成株式会社 メトクロプラミドの製造方法
FR2446274A1 (fr) * 1979-01-15 1980-08-08 Delalande Sa Nouveaux derives de salicylamide, leur procede de preparation et leur application en therapeutique
US4301159A (en) * 1980-06-20 1981-11-17 Shionogi & Co., Ltd. N-(Diethylaminoethyl)-2-alkoxy-benzamide derivatives
US4440941A (en) * 1980-12-22 1984-04-03 Usv Pharmaceutical Corporation Aroyl-aminoacids, amides and esters thereof
US4536386B1 (en) * 1981-01-26 1995-03-07 Robins Co Inc A H Method of controlling emesis caused by cisplatin in cancer chemotherapy
US4666911A (en) * 1981-07-14 1987-05-19 Taiho Pharmaceutical Company Limited Allophanoylpiperazine compound and analgesic composition containing same as active ingredient
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
US5011992A (en) * 1984-06-28 1991-04-30 Bristol-Myers Squibb Company Pharmacologically active substituted benzamides
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
GB8708833D0 (en) * 1987-04-13 1987-05-20 Lilly S A E Organic compounds
IT1216120B (it) * 1988-03-17 1990-02-22 Poli Ind Chimica Spa Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono.
GB8823040D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823042D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823041D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
FR2640139A1 (fr) * 1988-12-14 1990-06-15 Delagrange Laboratoires Application de benzamides substitues comme gastromoteurs
IT1266992B1 (it) * 1993-04-16 1997-01-24 Alfa Wassermann Spa Composti eterociclici, a struttura correlabile alle banzammidi, attivi nelle patologie gastro-intestinali, ad attivita' procinetica ed
US20040192781A1 (en) * 2003-03-31 2004-09-30 Haley Eugene T. Method of administration for metoclopramide and pharmaceutical formulation therefor
US20050137265A1 (en) * 2003-03-31 2005-06-23 Haley Eugene T. Rapidly dissolving metoclopramide solid oral dosage and method thereof
AU2005263577C1 (en) 2004-07-16 2010-08-26 Proteosys Ag Muscarinic antagonists with PARP and SiR modulating activity as cytoprotective agents
US20100099772A1 (en) 2006-11-20 2010-04-22 Bean Bruce P Methods, compositions, and kits for treating pain and pruritis
US20110294791A1 (en) 2009-01-13 2011-12-01 Proteosys Ag Pirenzepine as an agent in cancer treatment
WO2011006073A1 (en) 2009-07-10 2011-01-13 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
TR201811221T4 (tr) 2011-08-25 2018-08-27 Evoke Pharma Inc Dişi gastroparezi ile ilişkili semptomların tedavisi.
EP2895457B1 (en) 2012-09-17 2020-05-20 Nektar Therapeutics Oligomer-containing benzamide-based compounds
CA2994545A1 (en) 2015-08-03 2017-02-09 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
BR112021001966A2 (pt) 2018-08-15 2021-04-27 Pharmacyl Ab composto, composição farmacêutica, uso de um composto, e, método para o tratamento de uma doença resultante de inflamação patológica
KR20210045414A (ko) 2018-08-15 2021-04-26 파마실 아베 병리학적 염증에 대한 새로운 의학적 치료
SG11202109713PA (en) 2019-03-11 2021-10-28 Nocion Therapeutics Inc Ester substituted ion channel blockers and methods for use
KR20210145166A (ko) 2019-03-11 2021-12-01 녹시온 테라퓨틱스 인코포레이티드 하전된 이온 채널 차단제 및 사용 방법
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
KR20210143791A (ko) 2019-03-11 2021-11-29 녹시온 테라퓨틱스 인코포레이티드 하전된 이온 채널 차단제 및 사용 방법
MX2022005335A (es) 2019-11-06 2022-08-17 Nocion Therapeutics Inc Bloqueadores de canales ionicos cargados y metodos de uso.
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US11717500B2 (en) 2020-02-03 2023-08-08 Pharmacyl Ab Treatment of spondyloarthritis
IL295950A (en) 2020-03-11 2022-10-01 Nocion Therapeutics Inc Charged ion channel blockers and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620543A (US20030204162A1-20031030-M00001.png) *
US2460139A (en) * 1945-07-21 1949-01-25 Wallace & Tiernan Inc Alkamine esters of 2-chloro-4-amino benzoic acid
US2691025A (en) * 1951-03-30 1954-10-05 Sterling Drug Inc N-(tertiary-aminoalkyl)-2, 4-disubstituted-benzamides and their preparation
US2810718A (en) * 1953-07-02 1957-10-22 Abbott Lab Basic salicylamides
GB797476A (en) * 1955-09-09 1958-07-02 Bristol Lab Inc Amides of trialkoxybenzoic acids
US2910488A (en) * 1958-01-22 1959-10-27 Merck & Co Inc Aniline derivatives
NL281394A (US20030204162A1-20031030-M00001.png) * 1961-07-25

Also Published As

Publication number Publication date
JPS5145651B1 (US20030204162A1-20031030-M00001.png) 1976-12-04
SE313555B (US20030204162A1-20031030-M00001.png) 1969-08-18
DK106557C (da) 1967-02-20
BR6240890D0 (pt) 1973-06-14
NL281394A (US20030204162A1-20031030-M00001.png)
ES278660A1 (es) 1962-10-16
US3312739A (en) 1967-04-04
OA01153A (fr) 1968-08-07
FR1313758A (fr) 1963-01-04
US3177252A (en) 1965-04-06
FI42075B (US20030204162A1-20031030-M00001.png) 1970-02-02
JPS5216104B1 (US20030204162A1-20031030-M00001.png) 1977-05-06
SE372009B (US20030204162A1-20031030-M00001.png) 1974-12-09

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