CH159045A - Process for the preparation of 1- (di- (a-menaphtyl)) - aminoethan-2-ol. - Google Patents

Process for the preparation of 1- (di- (a-menaphtyl)) - aminoethan-2-ol.

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Publication number
CH159045A
CH159045A CH159045DA CH159045A CH 159045 A CH159045 A CH 159045A CH 159045D A CH159045D A CH 159045DA CH 159045 A CH159045 A CH 159045A
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CH
Switzerland
Prior art keywords
menaphtyl
aminoethan
preparation
reaction
alcohol
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH159045A publication Critical patent/CH159045A/en

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Description

  

  Verfahren zur Darstellung von     1-[Di-(a.menaphtyl)l-aminoäthan-2-ol.       Gegenstand der vorliegenden Erfindung  ist ein Verfahren zur Darstellung von     1-          [Di-(a-menaphtyl)]-aminoäthan-2-ol,    welches  dadurch gekennzeichnet ist,     dass    man     Athanol-          amin    mit     a-Menaphtylehlorid        CloH7(a)0H2.        Cl     umsetzt, am besten bei einer zwischen<B>60-110 0</B>  liegenden Temperatur.  



  Das zur Herstellung von neuen Heilmit  teln und Farbstoffen verwendbare neue Ver  fahrensprodukt hat den Schmelzpunkt<B>80</B> bis  <B>810</B>     C;    das salzsaure Salz ist in Wasser und  Alkohol wenig löslich, ist     umkristallisierbar     aus Methylalkohol und schmilzt bei 211 bis  212<B>0 C.</B>    <I>Beispiel:</I>  Zu<B>36</B> Gewichtsteilen     Äthanolamin    werden  unter Rühren<B>106</B> Gewichtsteile     a-Menaphtyl-          chlorid    bei<B>90-100 0</B>     zugetropft;    darauf wer  den 42     Gewichtsteile    pulverisiertes     Natrium-          carbonat    langsam zugesetzt.

   Das Gemisch  wird unter Rühren noch 2 Stunden auf<B>100</B> bis    <B>105 0</B> gehalten. Nach dem Erkalten wird  Wasser und Äther zugesetzt. Die nach dem  Durchschütteln abgetrennte, über     Kalium-          carbonat    getrocknete Ätherlösung gibt beim  Destillieren unter<B>3</B> mm Druck um<B>283 0</B>  siedendes     1-[Di-a-menaphtyl]-aminoäthanol    in  einer Ausbeute von<B>92</B> Gewichtsteilen. Es  geht über als bräunliches<B>01,</B> das bald erstarrt  und einen Schmelzpunkt von<B>80-81 '</B> zeigt.  Das salzsaure Salz ist in Wasser und in  Alkohol wenig löslich, kristallisiert schön aus  Methylalkohol und schmilzt bei 211-212<B>0 C.</B>



  Process for the preparation of 1- [di- (a.menaphtyl) l-aminoethan-2-ol. The present invention relates to a process for the preparation of 1- [di- (a-menaphtyl)] -aminoethan-2-ol, which is characterized in that ethanolamine with a-menaphthyl chloride CloH7 (a) 0H2. Cl converts, preferably at a temperature between <B> 60-110 0 </B>.



  The new process product that can be used to manufacture new medicinal products and dyes has a melting point of <B> 80 </B> to <B> 810 </B> C; The hydrochloric acid salt is sparingly soluble in water and alcohol, can be recrystallized from methyl alcohol and melts at 211 to 212 <B> 0 C. </B> <I> Example: </I> To <B> 36 </B> parts by weight Ethanolamine are added dropwise with stirring <B> 106 </B> parts by weight of a-menaphthyl chloride at <B> 90-100 </B>; then the 42 parts by weight of powdered sodium carbonate were slowly added.

   The mixture is held at <B> 100 </B> to <B> 1050 </B> for a further 2 hours with stirring. After cooling down, water and ether are added. The ether solution, which is separated off after shaking and dried over potassium carbonate, gives boiling 1- [di-a-menaphtyl] -aminoethanol in a distillation under 3 mm pressure of 283 0 Yield of <B> 92 </B> parts by weight. It turns over as a brownish <B> 01 </B> that soon solidifies and shows a melting point of <B> 80-81 '</B>. The hydrochloric acid salt is sparingly soluble in water and alcohol, crystallizes nicely from methyl alcohol and melts at 211-212 <B> 0 C. </B>

Claims (1)

PATENTANSPRUCH Verfahren zur Darstellung von 1-[Di-(a- menaphtyl)]-aminoäthan-2-ol, dadurch gekenn zeichnet, dass man Äthanolamin mit a- Menaphtylchlorid umsetzt. PATENT CLAIM Process for the preparation of 1- [di- (a- menaphtyl)] - aminoethan-2-ol, characterized in that ethanolamine is reacted with a-menaphtyl chloride. Das zur Herstellung von neuen Heilmit teln und Farbstoffen verwendbare neue Ver fahrensprodukt hat den Schmelzpunkt<B>80</B> bis <B>81 ' C;</B> das salzsaure Salz ist in Wasser und Alkohol wenig löslich, ist umkristalli- sierbar aus Methylalkohol und schmilzt bei 211-212<B>0 C.</B> UNTERANSPRüCIIE: <B>1.</B> Verführen nach Patentanspruch, dadurch gekennzeichnet, dass man die Umsetzung bei etwa<B>60-110 0</B> C ausführt. 2. Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man die Umsetzung in Gegenwart von säurebindenden Mitteln ausführt. The new process product that can be used to manufacture new medicinal products and dyes has a melting point of <B> 80 </B> to <B> 81 ° C; </B> the hydrochloric acid salt is not very soluble in water and alcohol, is recrystalline sable from methyl alcohol and melts at 211-212 <B> 0 C. </B> SUBCLAIM: <B> 1. </B> Seduction according to patent claim, characterized in that the reaction is carried out at about <B> 60-110 0 </B> C executes. 2. The method according to claim, characterized in that the reaction is carried out in the presence of acid-binding agents. <B>3.</B> Verfahren nach Patentanspruch und Unter anspruch 2, dadurch gekennzeichnet, dass man als säurebindendes Mittel Kalium- earbonat verwendet. <B> 3. </B> Process according to claim and sub-claim 2, characterized in that potassium carbonate is used as the acid-binding agent.
CH159045D 1930-06-10 1931-06-08 Process for the preparation of 1- (di- (a-menaphtyl)) - aminoethan-2-ol. CH159045A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE159045X 1930-06-10
CH154820T 1931-06-08

Publications (1)

Publication Number Publication Date
CH159045A true CH159045A (en) 1932-12-15

Family

ID=25716513

Family Applications (1)

Application Number Title Priority Date Filing Date
CH159045D CH159045A (en) 1930-06-10 1931-06-08 Process for the preparation of 1- (di- (a-menaphtyl)) - aminoethan-2-ol.

Country Status (1)

Country Link
CH (1) CH159045A (en)

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