CH149252A - Process for the preparation of 4-glycolylamino-3'-amino-4'-oxy-arsenobenzene. - Google Patents

Process for the preparation of 4-glycolylamino-3'-amino-4'-oxy-arsenobenzene.

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Publication number
CH149252A
CH149252A CH149252DA CH149252A CH 149252 A CH149252 A CH 149252A CH 149252D A CH149252D A CH 149252DA CH 149252 A CH149252 A CH 149252A
Authority
CH
Switzerland
Prior art keywords
amino
glycolylamino
preparation
arsenobenzene
oxy
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH149252A publication Critical patent/CH149252A/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Description

  

  Verfahren zur Darstellung von     4-Glykolylamino-3'-amino-4'-oxy-arsenobenzol,       Im Patent Nr. 144432 wurde die Dar  stellung des     4-Glykolylamino-3'-amino-4'-oxy-          arsenobenzols    durch\ Reduktion eines Ge  misches der entsprechenden     Arsinsäuren    be  schrieben.  



  Es wurde nun gefunden, dass man diese  Verbindung auch erhalten kann, indem man  die eine Komponente in Form ihres     Arsins     mit der andern Komponente in Form ihres       Arsinoxyds    oder des entsprechenden     Dichlor-          arsins    oder umgekehrt kondensiert.  



  Gegenstand dieses Patentes ist ein Ver  fahren zur     Darstellung    von     4-Glykolylairiino-          3'-amino-4'-oxyarsenobenzol,    welches dadurch  gekennzeichnet ist, dass man     4-Glykolylamino-          benzolarsinoxyd    mit     3-Amino-4-oxybenzol-          arsin    kondensiert.  



  Das Endprodukt ist ein gelbes, in ver  dünnter Natronlauge leicht lösliches Pulver.  Es zeichnet sieh durch geringe Giftigkeit und  hohen Heilwert aus.    <I>Beispiel:</I>  24,1     gr        4-Glykolylaminobenzolarsiiioxyd     werden in 500     cin3        1/zo    n alkoholischer Salz  säure gelöst und unter Rühren eine     Lösung     von 18,5     gr        3-Amino-4-oxyplienylarsin    in  250     em3    Alkohol zugegeben. Nach kurzer  Zeit beginnt sich das gebildete     Arsenobenzol     abzuscheiden. Nach einer Stunde wird abge  saugt und mit Wasser, Alkohol und Äther  nachgewaschen.

   Ausbeute 35     gr.  



  Process for the preparation of 4-glycolylamino-3'-amino-4'-oxy-arsenobenzene, In patent no. 144432 the presentation of the 4-glycolylamino-3'-amino-4'-oxy-arsenobenzene by \ reduction of a Ge mixture of the corresponding arsinic acids be written.



  It has now been found that this compound can also be obtained by condensing one component in the form of its arsine with the other component in the form of its arsine oxide or the corresponding dichloro arsine or vice versa.



  The subject of this patent is a process for the preparation of 4-glycolylamino-3'-amino-4'-oxyarsenobenzene, which is characterized in that 4-glycolylamino-benzolarsinoxide is condensed with 3-amino-4-oxybenzene arsine.



  The end product is a yellow powder that is easily soluble in dilute sodium hydroxide solution. It is characterized by low toxicity and high healing value. <I> Example: </I> 24.1 grams of 4-glycolylaminobenzolar oxide are dissolved in 500 cubic centimeters of alcoholic hydrochloric acid and a solution of 18.5 grams of 3-amino-4-oxyplienylarsine in 250 cubic meters of alcohol is added with stirring . After a short time, the arsenobenzene formed begins to separate out. After one hour, it is filtered off and washed with water, alcohol and ether.

   Yield 35 gr.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von 4-Calykoly1- amino-3'-amino-4'-oxyarsenobenzol, dadurch gekennzeichnet, dass man 4-Glykulyiamino- benzolarsinoxyd mit 3-Ainino-4-oxybenzolai-siii kondensiert. Das Endprodukt ist ein gelbes, in ver dünnter Natronlauge leicht lösliches Pulver. Es zeichnet sich durch geringe Giftigkeit und hohen Heilwert aus. Claim: Process for the preparation of 4-Calykoly1-amino-3'-amino-4'-oxyarsenobenzene, characterized in that 4-Glykulyiamino-benzolar oxide is condensed with 3-Ainino-4-oxybenzolai-siii. The end product is a yellow powder that is easily soluble in dilute sodium hydroxide solution. It is characterized by low toxicity and high healing value.
CH149252D 1929-08-27 1930-08-08 Process for the preparation of 4-glycolylamino-3'-amino-4'-oxy-arsenobenzene. CH149252A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE149252X 1929-08-27

Publications (1)

Publication Number Publication Date
CH149252A true CH149252A (en) 1931-08-31

Family

ID=5673226

Family Applications (1)

Application Number Title Priority Date Filing Date
CH149252D CH149252A (en) 1929-08-27 1930-08-08 Process for the preparation of 4-glycolylamino-3'-amino-4'-oxy-arsenobenzene.

Country Status (1)

Country Link
CH (1) CH149252A (en)

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