CA2768318A1 - Novel .delta.9-elongase for production of polyunsaturated fatty acid-enriched oils - Google Patents
Novel .delta.9-elongase for production of polyunsaturated fatty acid-enriched oils Download PDFInfo
- Publication number
- CA2768318A1 CA2768318A1 CA2768318A CA2768318A CA2768318A1 CA 2768318 A1 CA2768318 A1 CA 2768318A1 CA 2768318 A CA2768318 A CA 2768318A CA 2768318 A CA2768318 A CA 2768318A CA 2768318 A1 CA2768318 A1 CA 2768318A1
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- Prior art keywords
- acid
- polyunsaturated fatty
- elongase
- cell
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- DJJCXFVJDGTHFX-XVFCMESISA-N uridine 5'-monophosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(=O)NC(=O)C=C1 DJJCXFVJDGTHFX-XVFCMESISA-N 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 150000004669 very long chain fatty acids Chemical class 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
- 235000013618 yogurt Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Fats And Perfumes (AREA)
- Edible Oils And Fats (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/505,293 | 2009-07-17 | ||
| US12/505,293 US8188335B2 (en) | 2009-07-17 | 2009-07-17 | Δ9-elongase for production of polyunsaturated fatty acid-enriched oils |
| PCT/US2010/041893 WO2011008803A2 (en) | 2009-07-17 | 2010-07-14 | Novel δ9-elongase for production of polyunsaturated fatty acid-enriched oils |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2768318A1 true CA2768318A1 (en) | 2011-01-20 |
Family
ID=42651221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2768318A Abandoned CA2768318A1 (en) | 2009-07-17 | 2010-07-14 | Novel .delta.9-elongase for production of polyunsaturated fatty acid-enriched oils |
Country Status (15)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102559364B (zh) | 2004-04-22 | 2016-08-17 | 联邦科学技术研究组织 | 用重组细胞合成长链多不饱和脂肪酸 |
| CA2884237C (en) | 2004-04-22 | 2020-09-08 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| AU2007291937B2 (en) | 2006-08-29 | 2014-05-15 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of fatty acids |
| CN102317459A (zh) | 2008-11-18 | 2012-01-11 | 联邦科学技术研究组织 | 产生ω-3脂肪酸的酶和方法 |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| US8293790B2 (en) | 2011-10-19 | 2012-10-23 | Dignity Sciences Limited | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof |
| US9096815B2 (en) * | 2011-11-29 | 2015-08-04 | Dignity Sciences Limited | Compositions comprising 20-carbon fatty acids and methods of making and using same |
| EA036786B1 (ru) | 2012-06-15 | 2020-12-21 | Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн | Выработка длинноцепочечных полиненасыщенных жирных кислот в растительных клетках |
| KR102535223B1 (ko) | 2013-12-18 | 2023-05-30 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 장쇄 다중불포화 지방산을 포함하는 지질 |
| PH12016502586B1 (en) | 2014-06-27 | 2023-07-19 | Commw Scient Ind Res Org | Lipid comprising docosapentaenoic acid |
| SG11201708106TA (en) | 2015-04-08 | 2017-10-30 | Euglena Co Ltd | Suppressive agent for rheumatoid arthritis, prophylactic agent for rheumatoid arthritis, therapeutic agent for rheumatoid arthritis, and food for suppressing rheumatoid arthritis |
| CN109563517A (zh) | 2016-06-01 | 2019-04-02 | 加拿大国家研究委员会 | 菟葵脂肪酸延伸酶及其在脂肪酸生产中的用途 |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR8108820A (pt) | 1980-09-24 | 1982-08-24 | Cetus Corp | Processo e sonda de diagnostico |
| US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| ATE53862T1 (de) | 1982-01-22 | 1990-06-15 | Cetus Corp | Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel. |
| US4683194A (en) | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US4943674A (en) | 1987-05-26 | 1990-07-24 | Calgene, Inc. | Fruit specific transcriptional factors |
| US5420034A (en) | 1986-07-31 | 1995-05-30 | Calgene, Inc. | Seed-specific transcriptional regulation |
| GB8507058D0 (en) | 1985-03-19 | 1985-04-24 | Efamol Ltd | Pharmaceutical & dietary compositions |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| GB8524276D0 (en) | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| GB8524275D0 (en) | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| US5107065A (en) | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| US5188958A (en) | 1986-05-29 | 1993-02-23 | Calgene, Inc. | Transformation and foreign gene expression in brassica species |
| CA1338457C (en) | 1986-08-22 | 1996-07-16 | Henry A. Erlich | Purified thermostable enzyme |
| US5004863B2 (en) | 1986-12-03 | 2000-10-17 | Agracetus | Genetic engineering of cotton plants and lines |
| US5416011A (en) | 1988-07-22 | 1995-05-16 | Monsanto Company | Method for soybean transformation and regeneration |
| IE63225B1 (en) | 1988-09-13 | 1995-04-05 | Efamol Holdings | Use of fatty acids in the treatment of myalgic encephalomyelitis |
| US5231020A (en) | 1989-03-30 | 1993-07-27 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
| US5106739A (en) | 1989-04-18 | 1992-04-21 | Calgene, Inc. | CaMv 355 enhanced mannopine synthase promoter and method for using same |
| US5175095A (en) | 1989-07-19 | 1992-12-29 | Calgene, Inc. | Ovary-tissue transcriptional factors |
| DE69103753T3 (de) | 1990-05-25 | 2008-01-24 | E.I. Dupont De Nemours And Co., Wilmington | Nukleotidsequenz des gens für stearoyl-acp-desaturase aus soja. |
| US5518908A (en) | 1991-09-23 | 1996-05-21 | Monsanto Company | Method of controlling insects |
| PH31293A (en) | 1991-10-10 | 1998-07-06 | Rhone Poulenc Agrochimie | Production of y-linolenic acid by a delta6-desaturage. |
| DK0616644T3 (da) | 1991-12-04 | 2003-10-27 | Du Pont | Fedtsyredesaturase-gener fra planter |
| ES2160591T3 (es) | 1991-12-06 | 2001-11-16 | Genentech Inc | Celulas transformadas por convertasas prohormonales. |
| US5912120A (en) | 1992-04-09 | 1999-06-15 | The United States Of America As Represented By The Department Of Health And Human Services, | Cloning, expression and diagnosis of human cytochrome P450 2C19: the principal determinant of s-mephenytoin metabolism |
| DE69333025T2 (de) | 1992-11-17 | 2004-04-29 | E.I. Du Pont De Nemours And Co., Wilmington | Für mikrosom delta 12 fettsäuredesaturase kodierende gene und verwandte enzyme von pflanzen |
| DK0686197T3 (da) | 1993-02-26 | 2000-09-04 | Calgene Llc | Geminivirusbaseret genekspressionssystem |
| US5750176A (en) | 1994-03-09 | 1998-05-12 | Abbott Laboratories | Transgenic non-human mammal milk comprising 2'-fucosyl-lactose |
| EP0750671A1 (en) | 1994-03-09 | 1997-01-02 | Abbott Laboratories | Transgenic animals producing oligosaccharides and glycoconjugates |
| CA2184687A1 (en) | 1994-03-09 | 1995-09-14 | Pedro Antonio Prieto | Humanized milk |
| US5631152A (en) | 1994-10-26 | 1997-05-20 | Monsanto Company | Rapid and efficient regeneration of transgenic plants |
| US5654402A (en) | 1994-10-26 | 1997-08-05 | Michigan State University | Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase |
| BRPI0620552A2 (pt) * | 2005-11-23 | 2011-11-22 | Du Pont | polinucleotìdeo isolado, polipeptìdeo delta-9 elongase, construção recombinante, célula vegetal, método para transformar uma célula, método para produção de uma planta transgênica, sementes transgênicas, método para fabricar ácidos graxos poliinsaturados de cadeia longa, óleos, método para produzir pelo menos um ácido graxo poliinsaturado, plantas de semente oleaginosa, sementes, alimentos, fragmento de ácido nucléico isolado e progênies de plantas |
| US7678560B2 (en) * | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
| EP2441843A1 (en) | 2007-02-12 | 2012-04-18 | E. I. du Pont de Nemours and Company | Production of arachidonic acid in oilseed plants |
| RS20090413A (en) | 2007-04-03 | 2010-06-30 | E. I. Du Pont De Nemours And Company | Multizymes and their use in making polyunsaturated fatty acids |
| US8119860B2 (en) * | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| AU2009302522B2 (en) | 2008-10-06 | 2015-03-26 | Abbott Laboratires | Delta-8 desaturase genes, enzymes encoded thereby and uses thereof |
-
2009
- 2009-07-17 US US12/505,293 patent/US8188335B2/en not_active Expired - Fee Related
-
2010
- 2010-07-14 CN CN201080041384.1A patent/CN102782124B/zh not_active Expired - Fee Related
- 2010-07-14 WO PCT/US2010/041893 patent/WO2011008803A2/en active Application Filing
- 2010-07-14 CA CA2768318A patent/CA2768318A1/en not_active Abandoned
- 2010-07-14 UA UAA201201733A patent/UA107468C2/uk unknown
- 2010-07-14 MX MX2012000825A patent/MX2012000825A/es active IP Right Grant
- 2010-07-14 NZ NZ597679A patent/NZ597679A/xx not_active IP Right Cessation
- 2010-07-14 RU RU2012103248/10A patent/RU2558302C2/ru not_active IP Right Cessation
- 2010-07-14 JP JP2012520732A patent/JP2012533303A/ja active Pending
- 2010-07-14 IN IN469DEN2012 patent/IN2012DN00469A/en unknown
- 2010-07-14 BR BRBR112012001125-1A patent/BR112012001125A2/pt not_active IP Right Cessation
- 2010-07-14 AU AU2010273508A patent/AU2010273508B2/en not_active Ceased
- 2010-07-14 MY MYPI2012000210A patent/MY160166A/en unknown
- 2010-07-16 AR ARP100102621A patent/AR077763A1/es unknown
- 2010-07-17 EP EP10737154A patent/EP2454365A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012001125A2 (pt) | 2015-09-01 |
| RU2558302C2 (ru) | 2015-07-27 |
| US8188335B2 (en) | 2012-05-29 |
| WO2011008803A3 (en) | 2011-04-07 |
| CN102782124A (zh) | 2012-11-14 |
| US20110016585A1 (en) | 2011-01-20 |
| WO2011008803A2 (en) | 2011-01-20 |
| NZ597679A (en) | 2013-06-28 |
| MX2012000825A (es) | 2012-04-19 |
| UA107468C2 (uk) | 2015-01-12 |
| AU2010273508A1 (en) | 2012-02-09 |
| MY160166A (en) | 2017-02-28 |
| IN2012DN00469A (enrdf_load_stackoverflow) | 2015-06-05 |
| EP2454365A2 (en) | 2012-05-23 |
| CN102782124B (zh) | 2015-04-22 |
| AU2010273508B2 (en) | 2015-02-05 |
| RU2012103248A (ru) | 2013-08-27 |
| JP2012533303A (ja) | 2012-12-27 |
| AR077763A1 (es) | 2011-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20150616 |
|
| FZDE | Discontinued |
Effective date: 20170714 |